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ME00058B - Derivati aminoindazola, postupak izrade i međuproizvodi ovog postupka kao medicinski produkti i farmaceutske kompozicije koje ih sadrži - Google Patents

Derivati aminoindazola, postupak izrade i međuproizvodi ovog postupka kao medicinski produkti i farmaceutske kompozicije koje ih sadrži

Info

Publication number
ME00058B
ME00058B MEP-2008-161A MEP2008161A ME00058B ME 00058 B ME00058 B ME 00058B ME P2008161 A MEP2008161 A ME P2008161A ME 00058 B ME00058 B ME 00058B
Authority
ME
Montenegro
Prior art keywords
procedure
heteroarylalkyl
derivatives
aminoindasol
intermediates
Prior art date
Application number
MEP-2008-161A
Other languages
English (en)
French (fr)
Inventor
Rosset Gilles Dutruc
Dominique Lesuisse
Thomas Rooney
Franck Halley
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of ME00058B publication Critical patent/ME00058B/me

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    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P31/14—Antivirals for RNA viruses
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
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    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

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  • Neurology (AREA)
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  • Communicable Diseases (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pronalazak se odnosi na nove derivate indazola koji imaju opštu formulu (I): pri čemu je R O, S ili NH; R3 je alkil, aril,arilalkil, heteroaril, heteroarilalkil, aril, heterociklil, cikloalkil, alkenil itd., radikal; navedeni radikali su opciono supstituisanisa 1 ili više supstituenata; R4, R5, R6 i R7 su nezavisno izabrani od sledećih radikala: vodonika, halogena, CN, N02, NH2,OH, COOH, C(O)OR8, -O-C(O)R8, NR8R9, NHC(O)R8, C(O)NR8R9, NHC(S)R8, C(S)NR8R9, SR8, S(O)R8, S02R8,NHS02R8, S02NR8R9, trifluorometil, trifluorometoksi, alkil, alkoksi, aril, arilalkil, heteroaril, heteroarilalkil, heterociklil,cikloalkil, alkenil itd., navedeni radikali su opciono supstituisani sa 1 ili više supstituenata.
MEP-2008-161A 2002-03-11 2003-03-07 Derivati aminoindazola, postupak izrade i međuproizvodi ovog postupka kao medicinski produkti i farmaceutske kompozicije koje ih sadrži ME00058B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0202997A FR2836915B1 (fr) 2002-03-11 2002-03-11 Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
EP03744396.7A EP1487804B1 (fr) 2002-03-11 2003-03-07 Derives d'aminoindazoles comme inhibiteurs de proteine-kinase
PCT/FR2003/000752 WO2003078403A2 (fr) 2002-03-11 2003-03-07 Derives d’aminoindazoles comme inhibiteurs de proteine-kinase

Publications (1)

Publication Number Publication Date
ME00058B true ME00058B (me) 2010-10-10

Family

ID=27763685

Family Applications (2)

Application Number Title Priority Date Filing Date
MEP-161/08A MEP16108A (en) 2002-03-11 2003-03-07 Derives d'aminoindazoles comme inhibiteurs de proteine-kinase
MEP-2008-161A ME00058B (me) 2002-03-11 2003-03-07 Derivati aminoindazola, postupak izrade i međuproizvodi ovog postupka kao medicinski produkti i farmaceutske kompozicije koje ih sadrži

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MEP-161/08A MEP16108A (en) 2002-03-11 2003-03-07 Derives d'aminoindazoles comme inhibiteurs de proteine-kinase

Country Status (30)

Country Link
US (1) US6949579B2 (me)
EP (1) EP1487804B1 (me)
JP (2) JP4648630B2 (me)
KR (1) KR101068770B1 (me)
CN (2) CN101962365A (me)
AR (1) AR038915A1 (me)
AU (1) AU2003242809B8 (me)
BR (1) BR0308373A (me)
CA (1) CA2478542C (me)
FR (1) FR2836915B1 (me)
GT (1) GT200300057A (me)
HR (1) HRP20040824B1 (me)
IL (2) IL163831A0 (me)
JO (1) JO2326B1 (me)
MA (1) MA27230A1 (me)
ME (2) MEP16108A (me)
MX (1) MXPA04007478A (me)
MY (1) MY138269A (me)
NO (1) NO329384B1 (me)
NZ (1) NZ535147A (me)
PA (1) PA8568301A1 (me)
PE (1) PE20040155A1 (me)
PL (1) PL370478A1 (me)
RS (1) RS52396B (me)
RU (1) RU2345070C2 (me)
SV (1) SV2003001494A (me)
TW (1) TWI329103B (me)
UY (1) UY27713A1 (me)
WO (1) WO2003078403A2 (me)
ZA (1) ZA200406687B (me)

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