[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

MC1220A1 - Nouveaux derives d'imidazolidine - Google Patents

Nouveaux derives d'imidazolidine

Info

Publication number
MC1220A1
MC1220A1 MC781334A MC1334A MC1220A1 MC 1220 A1 MC1220 A1 MC 1220A1 MC 781334 A MC781334 A MC 781334A MC 1334 A MC1334 A MC 1334A MC 1220 A1 MC1220 A1 MC 1220A1
Authority
MC
Monaco
Prior art keywords
imidazolidine
new derivatives
derivatives
new
Prior art date
Application number
MC781334A
Other languages
English (en)
Inventor
H Link
K Bernauer
H Stohler
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH546578A external-priority patent/CH642944A5/de
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1220A1 publication Critical patent/MC1220A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MC781334A 1977-10-28 1978-10-13 Nouveaux derives d'imidazolidine MC1220A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
LU78407 1977-10-28
CH546578A CH642944A5 (en) 1978-05-19 1978-05-19 Urea derivatives
CH936778 1978-09-06

Publications (1)

Publication Number Publication Date
MC1220A1 true MC1220A1 (fr) 1979-07-20

Family

ID=27175218

Family Applications (1)

Application Number Title Priority Date Filing Date
MC781334A MC1220A1 (fr) 1977-10-28 1978-10-13 Nouveaux derives d'imidazolidine

Country Status (26)

Country Link
US (2) US4407814A (fr)
EP (1) EP0001813B1 (fr)
JP (1) JPS5470271A (fr)
AR (2) AR219560A1 (fr)
AT (2) AT366374B (fr)
AU (1) AU522536B2 (fr)
BR (1) BR7807097A (fr)
CA (1) CA1107744A (fr)
CU (1) CU34980A (fr)
DE (2) DE2846946A1 (fr)
DK (1) DK481678A (fr)
ES (3) ES474592A1 (fr)
FI (1) FI68618C (fr)
FR (1) FR2422643A1 (fr)
GB (1) GB2008102B (fr)
GR (1) GR70681B (fr)
IE (1) IE47962B1 (fr)
IL (1) IL55773A (fr)
IT (1) IT1099450B (fr)
MC (1) MC1220A1 (fr)
NL (1) NL7810563A (fr)
NO (1) NO151461C (fr)
NZ (1) NZ188721A (fr)
PH (1) PH13569A (fr)
PT (1) PT68705A (fr)
SE (1) SE7811194L (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI801184A (fi) * 1979-04-24 1980-10-25 Hoffmann La Roche Foerfarande foer framstaellning av imidazolidinderivat
DE2933917A1 (de) * 1979-08-22 1981-03-26 Basf Ag, 67063 Ludwigshafen 5-imino-imidazolidin-2-one und diese enthaltende herbizide.
DE3134933A1 (de) * 1981-09-03 1983-03-31 Hoechst Ag, 6230 Frankfurt "harnstoffderivate, verfahren zu ihrer herstellung und diese enthaltende medikamente sowie deren verwendung"
DE3382406D1 (de) * 1982-04-08 1991-10-17 Shell Int Research Neue hydantoine, ihre herstellung und verwendung.
US5112983A (en) * 1987-09-28 1992-05-12 Olin Corporation Process for producing 1,2,4-triazol-5-one using organic sulfonic acids and polymers thereof as a catalyst
FR2671348B1 (fr) * 1991-01-09 1993-03-26 Roussel Uclaf Nouvelles phenylimidazolidines, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
US5411981A (en) * 1991-01-09 1995-05-02 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
FR2693461B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
USRE35956E (en) * 1991-01-09 1998-11-10 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
FR2694290B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
FR2724169B1 (fr) * 1994-09-06 1997-01-03 Roussel Uclaf Nouvelles phenylimidazolidines eventuellement substituees, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
FR2715402B1 (fr) * 1994-01-05 1996-10-04 Roussel Uclaf Nouvelles phénylimidazolines éventuellement substituées, leur procédé et des intermédiaires de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
TW521073B (en) * 1994-01-05 2003-02-21 Hoechst Marion Roussel Inc New optionally substituted phenylimidazolidines, their preparation process, their use as anti-androgenic agent and the pharmaceutical compositions containing them
FR2741346B1 (fr) * 1995-11-16 1997-12-19 Roussel Uclaf Nouveau procede de preparation de derives phenylimidazolidine
FR2741342B1 (fr) * 1995-11-22 1998-02-06 Roussel Uclaf Nouvelles phenylimidazolidines fluorees ou hydroxylees, procede, intermediaires de preparation, application comme medicaments, nouvelle utilisation et compositions pharmaceutiques
WO2002000617A2 (fr) * 2000-06-28 2002-01-03 Bristol-Myers Squibb Company Modulateurs selectifs des recepteurs androgeniques et leurs methodes d'identification, d'elaboration et d'utilisation
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
EP1854798A3 (fr) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Composés de succinimide hétérocyclique fondu et leurs analogies, modulateurs de la fonction de récepteur d'hormone nucléaire
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP2299266A1 (fr) * 2003-12-19 2011-03-23 The Regents of the University of California Procédés et matériels pour évaluer les thérapies du cancer de la prostate
AU2005232526B2 (en) * 2004-02-24 2011-06-23 The Regents Of The University Of California Methods and materials for assessing prostate cancer therapies and compounds
US7709517B2 (en) * 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
ES2588606T3 (es) 2006-03-27 2016-11-03 The Regents Of The University Of California Modulador del receptor de andrógenos para el tratamiento del cáncer de próstata y enfermedades asociadas con el receptor de andrógenos
KR20160027254A (ko) 2006-03-29 2016-03-09 더 리전트 오브 더 유니버시티 오브 캘리포니아 디아릴티오히단토인 화합물
US8680291B2 (en) 2007-10-26 2014-03-25 The Regents Of The University Of California Diarylhydantoin compounds
EA023981B1 (ru) 2010-02-16 2016-08-31 Арагон Фармасьютикалс, Инк. Модуляторы рецептора андрогенов и их применение
EA037806B1 (ru) 2012-09-26 2021-05-24 Арагон Фармасьютикалз, Инк. Способ лечения неметастатического кастрационно-резистентного рака простаты
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
WO2019078920A1 (fr) 2017-10-16 2019-04-25 Aragon Pharmaceuticals, Inc. Anti-androgènes destinés au traitement du cancer de la prostate résistant à la castration, non métastatique

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629779A (fr) *
US3134663A (en) * 1957-07-23 1964-05-26 Geigy Chem Corp Herbicidal composition and method employing hydantoins
FR1405725A (fr) * 1963-08-23 1965-07-09 Shell Int Research Procédé de préparation de la 5, 5-diméthyl-4-iminohydantoine
DK122816B (da) * 1968-03-28 1972-04-17 Ciba Geigy Ag Analogifremgangsmåde til fremstilling af 3-aryl-5-methylhydantoiner.
US3690863A (en) * 1968-04-19 1972-09-12 Du Pont Esters of 3-(carboxyamino)-and 3-(thiocarboxyamino)-2-substituted crotonamides andtheir use as herbicides
DK123717B (da) * 1968-11-25 1972-07-24 Sumitomo Chemical Co 3-(3',5'-Dihalogenphenyl)-imidazolidin-2,4-dionderivater med mirobicid virkning.
JPS4916937B1 (fr) * 1970-01-21 1974-04-25
US3676456A (en) * 1970-02-27 1972-07-11 Ciba Geigy Corp Derivatives of 3-aryl-5-alkylhydantoins
JPS5136332B1 (fr) * 1970-12-09 1976-10-07
US4044021A (en) * 1971-10-21 1977-08-23 American Cyanamid Company Tetrasubstituted imidazolidine diuretics useful in the treatment of hyperaldosteronism
IL45459A (en) * 1973-09-03 1978-01-31 Ciba Geigy Ag 1-(dichlorofluoromethylthio)-3-phenyl-imidazolidine-2,4-dione derivatives their preparation and their use as bactericides and fungicides
FR2329276A1 (fr) * 1975-10-29 1977-05-27 Roussel Uclaf Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant
JPS5315373A (en) * 1976-07-29 1978-02-13 Mitsubishi Chem Ind Ltd Hydantoin derivatives and fungicides containing same for agriculture and horiticulture
IL55774A (en) * 1977-10-28 1982-04-30 Sparamedica Ag Pharmaceutical compositions containing urea derivatives,certain such novel derivatives and their manufacture
US4358606A (en) * 1981-06-19 1982-11-09 Zoecon Corporation Esters of phenalkyloxycarbonylamino acids

Also Published As

Publication number Publication date
DK481678A (da) 1979-04-29
BR7807097A (pt) 1979-05-08
AR220004A1 (es) 1980-09-30
EP0001813A1 (fr) 1979-05-16
ATA18281A (de) 1981-09-15
IL55773A0 (en) 1978-12-17
AR219560A1 (es) 1980-08-29
IT1099450B (it) 1985-09-18
FR2422643B1 (fr) 1982-10-29
JPS5470271A (en) 1979-06-05
ATA768978A (de) 1981-08-15
JPS625145B2 (fr) 1987-02-03
AU522536B2 (en) 1982-06-10
AT366671B (de) 1982-04-26
SE7811194L (sv) 1979-04-29
ES480109A1 (es) 1980-04-01
AT366374B (de) 1982-04-13
NZ188721A (en) 1984-11-09
US4482739A (en) 1984-11-13
US4407814A (en) 1983-10-04
IL55773A (en) 1982-02-28
GB2008102A (en) 1979-05-31
IE782130L (en) 1979-04-28
AU4096178A (en) 1980-05-01
NO783642L (no) 1979-05-02
FI68618B (fi) 1985-06-28
GR70681B (fr) 1982-12-20
GB2008102B (en) 1982-07-07
DE2846946A1 (de) 1979-05-03
FI68618C (fi) 1985-10-10
NL7810563A (nl) 1979-05-02
CU34980A (es) 1981-12-04
ES480114A1 (es) 1980-04-01
DE2861289D1 (en) 1982-01-14
NO151461B (no) 1985-01-02
FR2422643A1 (fr) 1979-11-09
EP0001813B1 (fr) 1981-11-04
CA1107744A (fr) 1981-08-25
NO151461C (no) 1985-04-17
PH13569A (en) 1980-06-26
FI783170A (fi) 1979-04-29
PT68705A (en) 1978-11-01
ES474592A1 (es) 1980-04-01
IT7829040A0 (it) 1978-10-24
IE47962B1 (en) 1984-08-08

Similar Documents

Publication Publication Date Title
MC1220A1 (fr) Nouveaux derives d'imidazolidine
BE869612A (fr) Preparation d'oligoimides
BE868532A (fr) Nouveaux derives de la thiazolidine
FR2348190A1 (fr) Derives quaternaires d'halo-alcanoates gras de dialkylamino-propylamides
BE857519A (fr) Nouveaux derives d'acides azolyl-carboxyliques
FR2348926A1 (fr) Nouveaux derives de l'adenine
BE853574A (fr) Nouveaux derives d'acides m-phenyl-phenoxy-propioniques
FR2298328A1 (fr) Nouveaux derives d'imidazole
BE848962A (fr) Nouveaux derives de l'indazole
MC1184A1 (fr) Derives d'oxadiazolopyrimidine
BE853578A (fr) Derives de thiouree
FR2332747A1 (fr) Derives d'a-aminocetones
BE866208A (fr) Derives de l'isoquinoleine hydrogenee
FR2322604A1 (fr) Derives 3-triazolylthio d'ureido-7a-methoxy-ou demethoxycephalosporines
BE856975A (fr) Nouveaux derives d'acides phenoxyphenoxy-alcanecarboxyliques
MC1183A1 (fr) Derives d'oxadiazolopyrimidine
BE859567A (fr) Derives piperidylideniques de benzo-xanthenes
BE862769A (fr) Nouveaux derives de la piperidine
PL204041A1 (pl) Sposob wytwarzania nowych pochodnych 4"-aminooleandomycyny
BE868590A (fr) Derives alpha-acetyleniques et alpha-vinyliques d'amino-acides
BE866933A (fr) Nouveaux derives de fortmicine
BE850089A (fr) Nouveaux derives de l'hydrazine
BE857512A (fr) Nouveaux derives de l'imidazole
BE873266A (fr) Nouveaux derives de 11-alcanoyl-4"-deoxy-4"-isonitrilo-oleandomycine
BE851463A (fr) Nouveaux derives d'indolizine

Legal Events

Date Code Title Description
YP Annual fee paid