MA49508A - Procédés de traitement d'une insuffisance cardiaque avec des activateurs de sarcomères cardiaques - Google Patents
Procédés de traitement d'une insuffisance cardiaque avec des activateurs de sarcomères cardiaquesInfo
- Publication number
- MA49508A MA49508A MA049508A MA49508A MA49508A MA 49508 A MA49508 A MA 49508A MA 049508 A MA049508 A MA 049508A MA 49508 A MA49508 A MA 49508A MA 49508 A MA49508 A MA 49508A
- Authority
- MA
- Morocco
- Prior art keywords
- sarcomera
- activators
- cardiac
- processes
- heart failure
- Prior art date
Links
- 206010019280 Heart failures Diseases 0.000 title 1
- 239000012190 activator Substances 0.000 title 1
- 230000000747 cardiac effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762527983P | 2017-06-30 | 2017-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA49508A true MA49508A (fr) | 2020-05-06 |
Family
ID=63013097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA049508A MA49508A (fr) | 2017-06-30 | 2018-06-29 | Procédés de traitement d'une insuffisance cardiaque avec des activateurs de sarcomères cardiaques |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11576910B2 (fr) |
| EP (1) | EP3645002B1 (fr) |
| JP (2) | JP2020526483A (fr) |
| CN (1) | CN110996953A (fr) |
| AU (2) | AU2018290983B2 (fr) |
| BR (1) | BR112019028046A2 (fr) |
| CA (1) | CA3068588A1 (fr) |
| MA (1) | MA49508A (fr) |
| MX (2) | MX2020000190A (fr) |
| WO (1) | WO2019006235A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014239995B2 (en) | 2013-03-14 | 2018-07-26 | Amgen Inc. | Salt of omecamtiv mecarbil and process for preparing salt |
| MA49508A (fr) | 2017-06-30 | 2020-05-06 | Amgen Inc | Procédés de traitement d'une insuffisance cardiaque avec des activateurs de sarcomères cardiaques |
| GEP20227340B (en) | 2017-06-30 | 2022-01-25 | Amgen Inc | Synthesis of omecamtiv mecarbil |
| WO2020037164A1 (fr) | 2018-08-17 | 2020-02-20 | Amgen Inc. | Sel et formes cristallines d'omecamtiv mecarbil |
| TW202233189A (zh) * | 2020-11-12 | 2022-09-01 | 美商安進公司 | 藉由投與奧美卡替莫卡必爾治療心臟衰竭之方法 |
| TW202300479A (zh) | 2021-03-10 | 2023-01-01 | 美商安進公司 | 奧美卡替莫卡必爾之合成 |
| WO2023164452A2 (fr) * | 2022-02-22 | 2023-08-31 | Yale University | Méthodes de traitement, d'atténuation ou de prévention de l'insuffisance cardiaque, et méthodes de promotion de la croissance des muscles cardiaques |
| WO2024081611A1 (fr) * | 2022-10-11 | 2024-04-18 | Cytokinetics, Incorporated | Méthodes de traitement de l'insuffisance cardiaque par administration d'activateurs de sarcomère cardiaque |
| US11986474B1 (en) | 2023-06-27 | 2024-05-21 | Cytokinetics, Incorporated | Methods for treating heart failure by administering cardiac sarcomere activators |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4450150A (en) | 1973-05-17 | 1984-05-22 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery depots, and method for preparing and using the same |
| CN1296417A (zh) | 1998-02-10 | 2001-05-23 | 卫福有限公司 | 控释制剂 |
| GB2344287A (en) | 1998-12-03 | 2000-06-07 | Ferring Bv | Controlled release pharmaceutical formulation |
| AU2003279842A1 (en) | 2002-10-04 | 2004-05-04 | Microchips, Inc. | Medical device for controlled drug delivery and cardiac monitoring and/or stimulation |
| EP1765327B1 (fr) | 2004-06-17 | 2014-08-13 | Cytokinetics, Inc. | Composes, compositions et procedes associes |
| TW200808321A (en) | 2005-12-15 | 2008-02-16 | Cytokinetics Inc | Certain chemical entities, compositions and methods |
| MX2008014418A (es) | 2006-05-15 | 2008-11-27 | Wisconsin Alumni Res Found | Administracion pulmonar de la 1 alfa, 25-dihidroxivitamina d3 y co-administracion de la homona paratiroidea o calcitonina. |
| FR2902092B1 (fr) | 2006-06-07 | 2008-09-05 | Sapelem Soc Par Actions Simpli | Appareil de manutention de charge |
| RU2422134C1 (ru) | 2007-04-19 | 2011-06-27 | Донг-А Фармасьютикал. Ко., Лтд | Композиция биоразлагающихся микросфер, пригодная для контролируемого высвобождения контролирующего уровень глюкозы пептида, и ее состав |
| AU2014239995B2 (en) | 2013-03-14 | 2018-07-26 | Amgen Inc. | Salt of omecamtiv mecarbil and process for preparing salt |
| WO2014152198A1 (fr) * | 2013-03-14 | 2014-09-25 | Amgen Inc. | Composés hétérocycliques et leurs utilisations |
| US20180022710A1 (en) | 2015-01-29 | 2018-01-25 | Signal Pharmaceuticals, Llc | Isotopologues of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide |
| MX2017016347A (es) | 2015-06-26 | 2018-08-15 | Amgen Inc | Terapia de combinacion de activador de miosina cardiaca e inhibidor de corriente if del nodo sinusal. |
| MA49508A (fr) | 2017-06-30 | 2020-05-06 | Amgen Inc | Procédés de traitement d'une insuffisance cardiaque avec des activateurs de sarcomères cardiaques |
| GEP20227340B (en) | 2017-06-30 | 2022-01-25 | Amgen Inc | Synthesis of omecamtiv mecarbil |
| HUE052049T2 (hu) | 2018-07-09 | 2021-04-28 | Fis Fabbrica Italiana Sintetici Spa | Kristályos 2-fluor-3-nitrotoluol és eljárás annak elõállítására |
| US11608318B2 (en) | 2018-07-12 | 2023-03-21 | Assia Chemical Industries Ltd. | Solid state forms of Omecamtiv mecarbil and Omecamtiv mecarbil diHCl |
| WO2020037164A1 (fr) | 2018-08-17 | 2020-02-20 | Amgen Inc. | Sel et formes cristallines d'omecamtiv mecarbil |
| US20220042055A1 (en) | 2018-12-18 | 2022-02-10 | Amgen Inc. | Method of reducing aromatic nitro compounds |
| WO2021053175A1 (fr) | 2019-09-19 | 2021-03-25 | Synthon B.V. | Sels d'omecamtiv mecarbil et formes solides de ceux-ci |
| US20220340542A1 (en) | 2019-09-19 | 2022-10-27 | Synthon B.V. | Salts of omecamtiv mecarbil and solid forms thereof |
| EP4041198A4 (fr) | 2019-10-09 | 2023-08-16 | Dr. Reddy's Laboratories Limited | Formes solides de dichlorhydrate d'omecamtiv mecarbil et procédés associés |
| WO2021070124A1 (fr) | 2019-10-09 | 2021-04-15 | Dr. Reddy’S Laboratories Limited | Nouveaux procédés destinés à la préparation de l'omécamtiv mécarbil |
| WO2021136477A1 (fr) | 2020-01-03 | 2021-07-08 | 苏州科睿思制药有限公司 | Co-cristal de dichlorhydrate du composé i et son procédé de préparation et son utilisation |
| US20230090391A1 (en) | 2020-02-10 | 2023-03-23 | Amgen Inc. | Omecamtiv mecarbil tablet |
| TW202233189A (zh) | 2020-11-12 | 2022-09-01 | 美商安進公司 | 藉由投與奧美卡替莫卡必爾治療心臟衰竭之方法 |
| TW202300479A (zh) | 2021-03-10 | 2023-01-01 | 美商安進公司 | 奧美卡替莫卡必爾之合成 |
| WO2023205291A2 (fr) | 2022-04-21 | 2023-10-26 | The Board Of Regents Of The University Of Oklahoma | Ciblage de tissu myocardique pour l'administration d'agents thérapeutiques et d'imagerie |
-
2018
- 2018-06-29 MA MA049508A patent/MA49508A/fr unknown
- 2018-06-29 BR BR112019028046-4A patent/BR112019028046A2/pt active Search and Examination
- 2018-06-29 WO PCT/US2018/040181 patent/WO2019006235A1/fr active Application Filing
- 2018-06-29 MX MX2020000190A patent/MX2020000190A/es unknown
- 2018-06-29 EP EP18745732.0A patent/EP3645002B1/fr active Active
- 2018-06-29 US US16/625,958 patent/US11576910B2/en active Active
- 2018-06-29 CA CA3068588A patent/CA3068588A1/fr active Pending
- 2018-06-29 CN CN201880053343.0A patent/CN110996953A/zh active Pending
- 2018-06-29 JP JP2019570045A patent/JP2020526483A/ja active Pending
- 2018-06-29 AU AU2018290983A patent/AU2018290983B2/en active Active
-
2020
- 2020-01-08 MX MX2022015115A patent/MX2022015115A/es unknown
-
2023
- 2023-01-17 US US18/155,483 patent/US20230149394A1/en active Pending
- 2023-03-15 JP JP2023040600A patent/JP2023088944A/ja active Pending
- 2023-05-05 US US18/313,267 patent/US11931358B2/en active Active
-
2024
- 2024-02-15 AU AU2024200991A patent/AU2024200991A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US11931358B2 (en) | 2024-03-19 |
| MX2020000190A (es) | 2020-07-22 |
| EP3645002A1 (fr) | 2020-05-06 |
| EP3645002B1 (fr) | 2024-10-30 |
| JP2020526483A (ja) | 2020-08-31 |
| WO2019006235A1 (fr) | 2019-01-03 |
| AU2018290983A1 (en) | 2020-01-23 |
| US11576910B2 (en) | 2023-02-14 |
| US20230355615A1 (en) | 2023-11-09 |
| MX2022015115A (es) | 2023-01-18 |
| AU2018290983B2 (en) | 2023-11-23 |
| CA3068588A1 (fr) | 2019-01-03 |
| JP2023088944A (ja) | 2023-06-27 |
| BR112019028046A2 (pt) | 2020-07-07 |
| US20200155547A1 (en) | 2020-05-21 |
| CN110996953A (zh) | 2020-04-10 |
| AU2024200991A1 (en) | 2024-03-07 |
| US20230149394A1 (en) | 2023-05-18 |
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