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MA22554A1 - Derives d'imidazo (1,2-a) (pyrrolo, thieno ou furano) (3,2-d) azepines, compositions les renfermant et methodes pour leur utilisation - Google Patents

Derives d'imidazo (1,2-a) (pyrrolo, thieno ou furano) (3,2-d) azepines, compositions les renfermant et methodes pour leur utilisation

Info

Publication number
MA22554A1
MA22554A1 MA22844A MA22844A MA22554A1 MA 22554 A1 MA22554 A1 MA 22554A1 MA 22844 A MA22844 A MA 22844A MA 22844 A MA22844 A MA 22844A MA 22554 A1 MA22554 A1 MA 22554A1
Authority
MA
Morocco
Prior art keywords
4alkyl
substituted
hydroxycarbonyl
represents hydrogen
4alkyloxy
Prior art date
Application number
MA22844A
Other languages
English (en)
Inventor
Janssens Fe
Diels Gsm
Cooyman Lp
Leenaerts Je
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MA22554A1 publication Critical patent/MA22554A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Lubricants (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Paper (AREA)
  • Detergent Compositions (AREA)
MA22844A 1991-06-13 1992-06-11 Derives d'imidazo (1,2-a) (pyrrolo, thieno ou furano) (3,2-d) azepines, compositions les renfermant et methodes pour leur utilisation MA22554A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71448791A 1991-06-13 1991-06-13

Publications (1)

Publication Number Publication Date
MA22554A1 true MA22554A1 (fr) 1992-12-31

Family

ID=24870247

Family Applications (1)

Application Number Title Priority Date Filing Date
MA22844A MA22554A1 (fr) 1991-06-13 1992-06-11 Derives d'imidazo (1,2-a) (pyrrolo, thieno ou furano) (3,2-d) azepines, compositions les renfermant et methodes pour leur utilisation

Country Status (26)

Country Link
US (1) US5461050A (fr)
EP (2) EP0518434A1 (fr)
JP (1) JP3182421B2 (fr)
KR (1) KR100247504B1 (fr)
CN (1) CN1033587C (fr)
AT (1) ATE247118T1 (fr)
AU (1) AU652841B2 (fr)
CA (1) CA2102889C (fr)
DE (1) DE69233161T2 (fr)
ES (1) ES2204892T3 (fr)
FI (1) FI104077B (fr)
HR (1) HRP920156A2 (fr)
HU (1) HU221013B1 (fr)
IE (1) IE921919A1 (fr)
IL (1) IL101851A (fr)
MA (1) MA22554A1 (fr)
MX (1) MX9202860A (fr)
NO (2) NO300689B1 (fr)
NZ (1) NZ242775A (fr)
PL (1) PL170376B1 (fr)
SI (1) SI9200104A (fr)
TN (1) TNSN92049A1 (fr)
TW (1) TW218382B (fr)
WO (1) WO1992022553A1 (fr)
ZA (1) ZA924327B (fr)
ZM (1) ZM2892A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them
GR1001385B (el) * 1992-10-12 1993-10-29 Janssen Pharmaceutica Nv Παράγωγα ιμιδαζο 1,2-α (πυρρολο,?ειενο η φουρανο) 3,2-d αζεπίνης συν?έσεις και μέ?οδοι χρήσεως.
DE69328976T2 (de) * 1992-12-04 2001-02-15 Janssen Pharmaceutica N.V., Beerse Antiallergisch triazolo (pyrrolo, thieno oder furano) azepinderivate
CA2150805C (fr) * 1992-12-04 2006-08-15 Frans Eduard Janssens Derives de l'imidazo[1,2-a](pyrrolo, thieno ou furano) [2,3-d]azepine ayant une action antiallergique
PL177224B1 (pl) * 1993-07-13 1999-10-29 Janssen Pharmaceutica Nv Nowy związek, pochodna imidazoazepiny, środek farmaceutyczny i sposób wytwarzania pochodnej imidazoazepiny
TW382017B (en) * 1995-12-27 2000-02-11 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives
TW527186B (en) 1996-03-19 2003-04-11 Janssen Pharmaceutica Nv Fused imidazole derivatives as multidrug resistance modulators
JP3882224B2 (ja) * 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
WO1999013871A2 (fr) * 1997-09-18 1999-03-25 Janssen Pharmaceutica N.V. Derives d'imidazole fusionnes aux fins de l'amelioration de la biodisponibilite d'agents pharmaceutiques
TR200101711T2 (tr) * 1998-12-19 2001-12-21 Janssen Pharmaceutica N.V. Antihistaminik spiro bileşikler.
TWI225488B (en) * 1999-12-21 2004-12-21 Janssen Pharmaceutica Nv Derivatives of homopiperidinyl substituted benzimidazole analogues
DK1401838T3 (da) 2001-06-12 2014-06-16 Janssen Pharmaceutica Nv Hidtil ukendte substituerede tetracykliske imidazolderivater, fremgangsmåder til fremstilling deraf, farmaceutiske præparater, der omfatter disse, og deres anvendelse som et lægemiddel
CN1852748A (zh) * 2003-07-23 2006-10-25 埃克塞里艾克西斯公司 用作药物的氮杂䓬衍生物
BRPI0608847A2 (pt) 2005-03-08 2010-02-02 Janssen Pharmaceutica Nv derivados de diaza-espiro-[4,4]-nonano substituìdos e seu uso como antagonistas de neurocinina
TWI498115B (zh) * 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
CN103570731B (zh) * 2012-07-30 2016-05-18 中国科学院广州生物医药与健康研究院 嘧啶并三环或嘧啶并四环类化合物及其药用组合物和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4148903A (en) * 1977-07-28 1979-04-10 Merck & Co., Inc. Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines
GB8900380D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
HRP920156A2 (en) 1995-12-31
DE69233161D1 (de) 2003-09-18
CA2102889C (fr) 2002-11-26
EP0588859B1 (fr) 2003-08-13
US5461050A (en) 1995-10-24
CA2102889A1 (fr) 1992-12-14
JPH06507890A (ja) 1994-09-08
KR100247504B1 (ko) 2000-05-01
ES2204892T3 (es) 2004-05-01
FI935557A0 (fi) 1993-12-10
ZM2892A1 (en) 1994-05-25
EP0518434A1 (fr) 1992-12-16
CN1033587C (zh) 1996-12-18
SI9200104A (en) 1992-12-31
ATE247118T1 (de) 2003-08-15
AU1901192A (en) 1993-01-12
NO934493L (no) 1994-01-04
HU9303554D0 (en) 1994-04-28
NO934493D0 (no) 1993-12-09
CN1068116A (zh) 1993-01-20
HUT70428A (en) 1995-10-30
NZ242775A (en) 1995-03-28
FI104077B1 (fi) 1999-11-15
EP0588859A1 (fr) 1994-03-30
MX9202860A (es) 1992-12-01
PL170376B1 (pl) 1996-12-31
IE921919A1 (en) 1992-12-16
AU652841B2 (en) 1994-09-08
TNSN92049A1 (fr) 1993-06-08
WO1992022553A1 (fr) 1992-12-23
IL101851A (en) 1996-05-14
FI104077B (fi) 1999-11-15
DE69233161T2 (de) 2004-05-27
FI935557A (fi) 1993-12-10
IL101851A0 (en) 1992-12-30
JP3182421B2 (ja) 2001-07-03
TW218382B (fr) 1994-01-01
ZA924327B (en) 1993-12-13
NO300689B1 (no) 1997-07-07
HU221013B1 (hu) 2002-07-29

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MA22554A1 (fr) Derives d'imidazo (1,2-a) (pyrrolo, thieno ou furano) (3,2-d) azepines, compositions les renfermant et methodes pour leur utilisation
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