Pu et al., 2016 - Google Patents
Mfsd2a+ hepatocytes repopulate the liver during injury and regenerationPu et al., 2016
View HTML- Document ID
- 3251187342562359940
- Author
- Pu W
- Zhang H
- Huang X
- Tian X
- He L
- Wang Y
- Zhang L
- Liu Q
- Li Y
- Li Y
- Zhao H
- Liu K
- Lu J
- Zhou Y
- Huang P
- Nie Y
- Yan Y
- Hui L
- Lui K
- Zhou B
- Publication year
- Publication venue
- Nature communications
External Links
Snippet
Hepatocytes are functionally heterogeneous and are divided into two distinct populations based on their metabolic zonation: the periportal and pericentral hepatocytes. During liver injury and regeneration, the cellular dynamics of these two distinct populations remain …
- 210000003494 Hepatocytes 0 title abstract description 257
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Pu et al. | Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration | |
| Huch et al. | In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration | |
| Kimura et al. | Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart | |
| Gauvrit et al. | HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development | |
| Hämäläinen et al. | Tissue-and cell-type–specific manifestations of heteroplasmic mtDNA 3243A> G mutation in human induced pluripotent stem cell-derived disease model | |
| Hammond et al. | The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/β-catenin signaling | |
| Blaas et al. | Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours | |
| Lorent et al. | Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy | |
| Fu et al. | A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development | |
| Kawaguchi et al. | Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis | |
| Cohen et al. | Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment | |
| Eferl et al. | AP-1: a double-edged sword in tumorigenesis | |
| Zhao et al. | Pre-existing beta cells but not progenitors contribute to new beta cells in the adult pancreas | |
| Fabian et al. | Lifelong single-cell profiling of cranial neural crest diversification in zebrafish | |
| Jin et al. | Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury | |
| Zaidan et al. | The multi-faceted role of Gata3 in developmental haematopoiesis | |
| Dong et al. | Identification of a regulatory pathway inhibiting adipogenesis via RSPO2 | |
| Liu et al. | Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle | |
| Jain | The many faces of RET dysfunction in kidney | |
| Dischinger et al. | NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer | |
| Witzel et al. | Isl2b regulates anterior second heart field development in zebrafish | |
| Pastore et al. | TFEB regulates murine liver cell fate during development and regeneration | |
| Liang et al. | Neural development is dependent on the function of specificity protein 2 in cell cycle progression | |
| Jones et al. | A comprehensive analysis of fibroblast growth factor receptor 2b signaling on epithelial tip progenitor cells during early mouse lung branching morphogenesis | |
| San et al. | Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2 |