[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Zaidan et al., 2018 - Google Patents

The multi-faceted role of Gata3 in developmental haematopoiesis

Zaidan et al., 2018

View HTML
Document ID
18328874974163128673
Author
Zaidan N
Ottersbach K
Publication year
Publication venue
Royal Society Open Biology

External Links

Snippet

The transcription factor Gata3 is crucial for the development of several tissues and cell lineages both during development as well as postnatally. This importance is apparent from the early embryonic lethality following germline Gata3 deletion, with embryos displaying a …
Continue reading at royalsocietypublishing.org (HTML) (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology

Similar Documents

Publication Publication Date Title
Zaidan et al. The multi-faceted role of Gata3 in developmental haematopoiesis
Kueh et al. Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment
Alvarez et al. Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality
Wang et al. Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell transcriptome level
Yin et al. Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity
Grajkowska et al. Isoform-specific expression and feedback regulation of E protein TCF4 control dendritic cell lineage specification
Pu et al. Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration
King et al. The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells
Zhao et al. Loss of β-catenin impairs the renewal of normal and CML stem cells in vivo
Gascoyne et al. The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development
Gao et al. Hedgehog signaling is dispensable for adult hematopoietic stem cell function
Park et al. Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs
Johnson et al. Cis-regulatory mechanisms governing stem and progenitor cell transitions
Yang et al. Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow
Frelin et al. GATA-3 regulates the self-renewal of long-term hematopoietic stem cells
Downing The core-binding factor leukemias: lessons learned from murine models
Galvis et al. Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung
Wilkinson et al. Transcriptional regulation of haematopoietic stem cells
Famili et al. Discrete roles of canonical and non-canonical Wnt signaling in hematopoiesis and lymphopoiesis
Castro et al. The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity
Andoniadou et al. HESX1-and TCF3-mediated repression of Wnt/β-catenin targets is required for normal development of the anterior forebrain
Goodnough et al. Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors
Storer et al. Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis
Liang et al. Neural development is dependent on the function of specificity protein 2 in cell cycle progression
Bera et al. RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia