TAKAHATA et al., 1990 - Google Patents
Microencapsulation of a Slightly Soluble Drug by Surface Neutralization Method Using an Enteric PolymerTAKAHATA et al., 1990
View PDF- Document ID
- 1964565363378669097
- Author
- TAKAHATA H
- KOIDA Y
- KOBAYASHI M
- SAMEJIMA M
- Publication year
- Publication venue
- Chemical and pharmaceutical bulletin
External Links
Snippet
抄録 Succeeding our previous study on enteric microencapsulation by surface neutralization method for acidic drugs, a new means of application was developed for the encapsulation of non-acidic drugs. Indomethacin was chosen as a model drug in this study because of its low …
- 239000003814 drug 0 title abstract description 25
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1052398C (en) | Pharmaceuctical spheroid formulation | |
| EP0294103B1 (en) | A sustained-release preparation and production thereof | |
| CA2169376C (en) | Procedure for encapsulating nsaids | |
| KR101862887B1 (en) | Diversion-resistant microgranules and microtablets | |
| US3074852A (en) | Pharmaceuticals with delayed release | |
| US5780055A (en) | Cushioning beads and tablet comprising the same capable of forming a suspension | |
| JP2916152B2 (en) | Drug release rate control type preparation | |
| DK160601B (en) | PHARMACEUTICAL RESPONSIBLE, SUSTAINED RELEASE PREPARATION WITH CONTROLLED RELEASE OF A PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALT OF DEXTROMETHORPHAN AND PROCEDURES FOR PREPARING THEREOF | |
| EP1258249A1 (en) | Oral preparations for diabetes | |
| CA2075355A1 (en) | Pharmaceutical combination formulation | |
| WO2006026504A2 (en) | Mucoadhesive oral formulations of high permeability, high solubility drugs | |
| Hashimoto et al. | Preparation, characterization and taste-masking properties of polyvinylacetal diethylaminoacetate microspheres containing trimebutine | |
| EP1072257A1 (en) | Multiple-unit sustained release tablets | |
| Lorenzo-Lamosam et al. | Development of a microencapsulated form of cefuroxime axetil using pH-sensitive acrylic polymers | |
| US5028433A (en) | Readily absorbable drug formulation of NB-818 | |
| WO1999049868A1 (en) | Sustained-release composition containing cefaclor | |
| WO2009101658A1 (en) | Timed-release pharmaceutical preparation | |
| CA2028633A1 (en) | Sustained-release preparation of basic medical agent hydrochloride | |
| TAKAHATA et al. | Microencapsulation of a Slightly Soluble Drug by Surface Neutralization Method Using an Enteric Polymer | |
| Wang et al. | In-vivo and in-vitro evaluations of a modified-release oral dosage form of nifedipine by hybridization of hydroxypropyl-β-cyclodextrin and hydroxypropylcelluloses in dogs | |
| US20030212102A1 (en) | Novel solid dispersion compositions | |
| WO2002003955A1 (en) | Fast release bioadhesive microspheres for the sublingual administration of proximate principles | |
| EP2175839B1 (en) | Controlled release pharmaceutical composition of tolperisone hydrochloride | |
| SOGO et al. | Influence of heat treatment on dissolution and masking degree of bitter taste for a novel fine granule system | |
| JPH10218761A (en) | Multiple unit type sustained release tablet |