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Waidner et al., 2011 - Google Patents

A microRNA of infectious laryngotracheitis virus can downregulate and direct cleavage of ICP4 mRNA

Waidner et al., 2011

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Document ID
17893610277834716550
Author
Waidner L
Burnside J
Anderson A
Bernberg E
German M
Meyers B
Green P
Morgan R
Publication year
Publication venue
Virology

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Snippet

Viral microRNAs regulate gene expression using either translational repression or mRNA cleavage and decay. Two microRNAs from infectious laryngotracheitis virus (ILTV), iltv-miR- I5 and iltv-miR-I6, map antisense to the ICP4 gene. Post-transcriptional repression by these …
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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