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Jeon et al., 2018 - Google Patents

Direct observation of DNA target searching and cleavage by CRISPR-Cas12a

Jeon et al., 2018

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Document ID
16223832654657555936
Author
Jeon Y
Choi Y
Jang Y
Yu J
Goo J
Lee G
Jeong Y
Lee S
Kim I
Kim J
Jeong C
Lee S
Bae S
Publication year
Publication venue
Nature communications

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Cas12a (also called Cpf1) is a representative type VA CRISPR effector RNA-guided DNA endonuclease, which provides an alternative to type II CRISPR–Cas9 for genome editing. Previous studies have revealed that Cas12a has unique features distinct from Cas9, but the …
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
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