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Naqvi et al., 2022 - Google Patents

CRISPR–Cas12a-mediated DNA clamping triggers target-strand cleavage

Naqvi et al., 2022

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Document ID
7038455576158330738
Author
Naqvi M
Lee L
Montaguth O
Diffin F
Szczelkun M
Publication year
Publication venue
Nature Chemical Biology

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Clustered regularly interspaced short palindromic repeats (CRISPR)–Cas12a is widely used for genome editing and diagnostics, so it is important to understand how RNA-guided DNA recognition activates the cleavage of the target strand (TS) following non-target-strand (NTS) …
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