Naqvi et al., 2022 - Google Patents
CRISPR–Cas12a-mediated DNA clamping triggers target-strand cleavageNaqvi et al., 2022
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- 7038455576158330738
- Author
- Naqvi M
- Lee L
- Montaguth O
- Diffin F
- Szczelkun M
- Publication year
- Publication venue
- Nature Chemical Biology
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Snippet
Clustered regularly interspaced short palindromic repeats (CRISPR)–Cas12a is widely used for genome editing and diagnostics, so it is important to understand how RNA-guided DNA recognition activates the cleavage of the target strand (TS) following non-target-strand (NTS) …
- 238000003776 cleavage reaction 0 title abstract description 160
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