Yarbrough et al., 1990 - Google Patents
A single base mutation in the androgen receptor gene causes androgen insensitivity in the testicular feminized rat.Yarbrough et al., 1990
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- 1307869039941181045
- Author
- Yarbrough W
- Quarmby V
- Simental J
- Joseph D
- Sar M
- Lubahn D
- Olsen K
- French F
- Wilson E
- Publication year
- Publication venue
- Journal of Biological Chemistry
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Snippet
The complete form of androgen insensitivity is an inherited X-linked syndrome in which genetic males fail to undergo masculinization in utero due to defective functioning of the androgen receptor (AR). The molecular basis of androgen insensitivity was investigated in …
- 108010080146 androgen receptors 0 title abstract description 172
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
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