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Beitel et al., 1994 - Google Patents

Complete androgen insensitivity due to mutations in the probable α-helical segments of the DNA-binding domain in the human androgen receptor

Beitel et al., 1994

Document ID
9922401391048116707
Author
Beitel L
Prior L
Vaslliou D
Gottlleb B
Kaufman M
Lumbroso R
Alvarado C
McGillivray B
Triflro M
Pinsky L
Publication year
Publication venue
Human Molecular Genetics

External Links

Snippet

We describe different single-amlno acid aberrations in the DNA-binding domain (DBD) of the human androgen receptor (hAR) in three families with complete androgen Insensitivity. No additional alteration was found in the translated portion of each mutant gene. In one …
Continue reading at academic.oup.com (other versions)

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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
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