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Kim et al., 2017 - Google Patents

Efficient modification of λ-DNA substrates for single-molecule studies

Kim et al., 2017

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Document ID
10624178375752747189
Author
Kim Y
De La Torre A
Leal A
Finkelstein I
Publication year
Publication venue
Scientific reports

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Snippet

Single-molecule studies of protein-nucleic acid interactions frequently require site-specific modification of long DNA substrates. The bacteriophage λ is a convenient source of high quality long (48.5 kb) DNA. However, introducing specific sequences, tertiary structures, and …
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/6802—General aspects
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