Koike et al., 2014 - Google Patents
Ring1B promotes hepatic stem/progenitor cell expansion through simultaneous suppression of Cdkn1a and Cdkn2a in miceKoike et al., 2014
View PDF- Document ID
- 1025883831136700753
- Author
- Koike H
- Ueno Y
- Naito T
- Shiina T
- Nakata S
- Ouchi R
- Obana Y
- Sekine K
- Zheng Y
- Takebe T
- Isono K
- Koseki H
- Taniguchi H
- Publication year
- Publication venue
- Hepatology
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Snippet
Polycomb‐group (PcG) proteins play crucial roles in self‐renewal of stem cells by suppressing a host of genes through histone modifications. Identification of the downstream genes of PcG proteins is essential for elucidation of the molecular mechanisms of stem cell …
- 210000000130 stem cell 0 title abstract description 110
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12N15/09—Recombinant DNA-technology
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- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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