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Isobutyl nitrite, C4H9NO2, is an alkyl nitrite, an ester of isobutanol and nitrous acid. Its chemical structure is (CH3)2CH-CH2-ONO.
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Names | |||
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Preferred IUPAC name
2-Methylpropyl nitrite | |||
Other names
Isobutyl nitrite
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Identifiers | |||
3D model (JSmol)
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ChEBI | |||
ChemSpider | |||
ECHA InfoCard | 100.008.018 | ||
PubChem CID
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UNII | |||
CompTox Dashboard (EPA)
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Properties | |||
C4H9NO2 | |||
Molar mass | 103.11976 | ||
Appearance | Colorless liquid | ||
Odor | Almond-like[2] | ||
Density | 0.87 g/mL | ||
Boiling point | 67 °C (153 °F; 340 K) | ||
Slightly soluble | |||
Hazards | |||
Occupational safety and health (OHS/OSH): | |||
Main hazards
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Highly flammable | ||
Legal status | |||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Isobutyl nitrite is a pungent colorless liquid. It acts as a vasodilator, and is used as an inhalant recreational drug, poppers.
Applications
editIsobutyl nitrite is one of the compounds used as poppers, an inhalant drug that induces a brief euphoria. Also, it is used as part of the antidote package for cyanide poisoning.[medical citation needed]
Safety
editMay cause headaches, dizziness and fainting. Isobutyl nitrite is poisonous to people with glucose-6-phosphate dehydrogenase deficiency.[5]
References
edit- ^ Merck Index, 11th Edition, 5032.
- ^ CDC - NIOSH Pocket Guide to Chemical Hazards
- ^ Therapeutic Goods (Poisons Standard—October 2024) Instrument 2024 (Cth)
- ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
- ^ Bubp, Jeff; Jen, Marilyn; Matuszewski, Karl (September 2015). "Caring for Glucose-6-Phosphate Dehydrogenase (G6PD)–Deficient Patients: Implications for Pharmacy". Pharmacy and Therapeutics. 40 (9): 572–574. ISSN 1052-1372. PMC 4571844. PMID 26417175.