Bacillolysin
| Bacillolysin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.24.28 | ||||||||
| CAS no. | 9080-56-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Bacillolysin (EC 3.4.24.28, Bacillus metalloendopeptidase, Bacillus subtilis neutral proteinase, anilozyme P 10, Bacillus metalloproteinase, Bacillus neutral proteinase, megateriopeptidase) is an enzyme.[1][2][3][4][5][6][7][8][9][10] This enzyme catalyses the following chemical reaction
- Similar, but not identical, to that of thermolysin
This enzyme is present in many Bacillus species, including B. subtilis, B. amyloliquefaciens, B. megaterium, B. mesentericus, B. cereus and B. stearothermophilus.
References
[edit]- ^ Morihara K, Tsuzuki H, Oka T (March 1968). "Comparison of the specificities of various neutral proteinases from microorganisms". Archives of Biochemistry and Biophysics. 123 (3): 572–88. doi:10.1016/0003-9861(68)90179-3. PMID 4967801.
- ^ Millet J, Acher R (July 1969). "[Specificity of megateriopeptidase: an amino-endopeptidase with hydrophobic characteristics]". European Journal of Biochemistry. 9 (4): 456–62. doi:10.1111/j.1432-1033.1969.tb00631.x. PMID 4980359.
- ^ Feder J, Keay L, Garrett LR, Cirulis N, Moseley MH, Wildi BS (October 1971). "Bacillus cereus neutral protease". Biochimica et Biophysica Acta (BBA) - Protein Structure. 251 (1): 74–8. doi:10.1016/0005-2795(71)90061-4. PMID 5002444.
- ^ Holmquist B, Vallee BL (January 1976). "Esterase activity of zinc neutral proteases". Biochemistry. 15 (1): 101–7. doi:10.1021/bi00646a016. PMID 2276.
- ^ Vasantha N, Thompson LD, Rhodes C, Banner C, Nagle J, Filpula D (September 1984). "Genes for alkaline protease and neutral protease from Bacillus amyloliquefaciens contain a large open reading frame between the regions coding for signal sequence and mature protein". Journal of Bacteriology. 159 (3): 811–9. doi:10.1128/JB.159.3.811-819.1984. PMC 215730. PMID 6090391.
- ^ Yang MY, Ferrari E, Henner DJ (October 1984). "Cloning of the neutral protease gene of Bacillus subtilis and the use of the cloned gene to create an in vitro-derived deletion mutation". Journal of Bacteriology. 160 (1): 15–21. doi:10.1128/JB.160.1.15-21.1984. PMC 214674. PMID 6090407.
- ^ Takagi M, Imanaka T, Aiba S (September 1985). "Nucleotide sequence and promoter region for the neutral protease gene from Bacillus stearothermophilus". Journal of Bacteriology. 163 (3): 824–31. doi:10.1128/JB.163.3.824-831.1985. PMC 219205. PMID 2993245.
- ^ Sidler W, Niederer E, Suter F, Zuber H (July 1986). "The primary structure of Bacillus cereus neutral proteinase and comparison with thermolysin and Bacillus subtilis neutral proteinase". Biological Chemistry Hoppe-Seyler. 367 (7): 643–57. doi:10.1515/bchm3.1986.367.2.643. PMID 3092843.
- ^ Pauptit RA, Karlsson R, Picot D, Jenkins JA, Niklaus-Reimer AS, Jansonius JN (February 1988). "Crystal structure of neutral protease from Bacillus cereus refined at 3.0 A resolution and comparison with the homologous but more thermostable enzyme thermolysin". Journal of Molecular Biology. 199 (3): 525–37. doi:10.1016/0022-2836(88)90623-7. PMID 3127592.
- ^ Stoeva S, Kleinschmidt T, Mesrob B, Braunitzer G (January 1990). "Primary structure of a zinc protease from Bacillus mesentericus strain 76". Biochemistry. 29 (2): 527–34. doi:10.1021/bi00454a029. PMID 2302386.
External links
[edit]- Bacillolysin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
