Mechanisms of Firing Patterns in Fast-Spiking Cortical Interneurons
Figure 7
Voltage Traces and Firing Patterns of the Model Neuron in Response to a Noisy Current Step
(A) Delayed tonic firing for θm = −24 mV, gd = 0.39 mS/cm2, Iapp = 3.35 μA/cm2.
(B) Delayed stuttering for θm = −24 mV, gd = 1.8 mS/cm2, Iapp = 4.2 μA/cm2.
(C) Delayed tonic firing for θm = −28 mV, gd = 0.39 mS/cm2, Iapp = 1.25 μA/cm2. In all three panels, the variance of the noise is D = 0.01 μA2 × ms/cm4. The time course of the mean applied current, Iapp, is also plotted. The membrane potentials during the delay periods are magnified in the panels on the right. Note the presence of subthreshold oscillations in (A) and (B). The peaks of these oscillations are denoted by the arrows.