[go: up one dir, main page]
More Web Proxy on the site http://driver.im/
Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Comment
  • Published:

Categorization of the gut microbiota: enterotypes or gradients?

Nature Reviews Microbiology volume 10, pages 591–592 (2012)Cite this article

Subjects

Abstract

Grouping the microbiota of individual subjects into compositional categories, or enterotypes, based on the dominance of certain genera may have oversimplified a complex situation.

Access through your institution
Buy or subscribe

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Roy, A. The God of Small Things. (Random House, 1997).

    Google Scholar 

  2. Arumugam, M. et al. Nature 473, 174–180 (2011).

    Article  CAS  Google Scholar 

  3. The Human Microbiome Project Consortium. Nature 486, 207–214 (2012).

  4. Claesson, M. J. et al. Proc. Natl Acad. Sci. USA 108 (Suppl. 1), 4586–4591 (2011).

    Article  CAS  Google Scholar 

  5. Siezen, R. J. & Kleerebezem, M. Microb. Biotechnol. 4, 550–553 (2011).

    Article  CAS  Google Scholar 

  6. Falush, D. et al. Science 299, 1582–1585 (2003).

    Article  CAS  Google Scholar 

  7. Muegge, B. D. et al. Science 332, 970–974 (2011).

    Article  CAS  Google Scholar 

  8. Walker, A. W. et al. ISME J. 5, 220–230 (2011).

    Article  CAS  Google Scholar 

  9. Wu, G. D. et al. Science 334, 105–108 (2011).

    Article  CAS  Google Scholar 

  10. De Filippo, C. et al. Proc. Natl Acad. Sci. USA 107, 14691–14696 (2010).

    Article  Google Scholar 

  11. O'Toole, P. W. & Claesson, M. J. Internat. Dairy J. 20, 281–291 (2010).

    Article  CAS  Google Scholar 

  12. Claesson, M. J. et al. Nature 13 Jul 2012 (doi: 10.1038/nature11319).

  13. Yong, E. Gut microbial 'enterotypes' become less clear-cut. NatureNews [online] (21 Mar 2012).

  14. Huse, S. M. et al. PLoS ONE 7, e34242 (2012).

    Article  CAS  Google Scholar 

  15. Faust, K. et al. PLoS Comput. Biol. 8, e1002606 (2012).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The authors are supported in part by Science Foundation Ireland, the Health Research Board, Ireland, and the Irish Government Department of Agriculture Food and the Marine.

Author information

Authors and Affiliations

  1. Marcus J. Claesson and Paul W. O'Toole are at the Department of Microbiology and the Alimentary Pharmabiotic Centre, Ian B. Jeffery, University College Cork, Western Road, Cork, Ireland.,

    Ian B. Jeffery, Marcus J. Claesson & Paul W. O'Toole

  2. Fergus Shanahan is at the Alimentary Pharmabiotic Centre and the Department of Medicine, University College Cork, Western Road, Cork, Ireland.,

    Fergus Shanahan

Authors
  1. Ian B. Jeffery
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Marcus J. Claesson
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Paul W. O'Toole
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Fergus Shanahan
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Paul W. O'Toole.

Ethics declarations

Competing interests

F. Shanahan declares an association with the following companies: Alimentary Health Ltd, GlaxoSmithKline Ltd and the Procter and Gamble Co. The content of this paper was neither influenced nor constrained by that fact. I. B. Jeffery, M. J. Claesson and P. W. O'Toole declare no competing financial interests.

Related links

Related links

FURTHER INFORMATION

Paul W. O'Toole's homepage

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jeffery, I., Claesson, M., O'Toole, P. et al. Categorization of the gut microbiota: enterotypes or gradients?. Nat Rev Microbiol 10, 591–592 (2012). https://doi.org/10.1038/nrmicro2859

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrmicro2859

This article is cited by

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research