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The changes of age-related molecules in the trophocytes and fat cells of queen honeybees (Apis mellifera)

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Abstract

Queen honeybees (Apis mellifera) have much longer lifespans than worker bees. Although the expression of age-related molecules in the trophocytes and fat cells of young and old workers have been determined, the expression of age-related molecules in queens is unknown. In this study, we examined the expression of age-related molecules in the trophocytes and fat cells of young and old queens. Molecular analyses detected no differences in telomerase activity or telomere lengths between trophocytes and fat cells from young and old queens, indicating that these cells do not divide in adulthood. Further assays showed that old queens has higher non-homogeneous cellular morphology, senescence-associated β-galactosidase (SA-β-Gal) activity, accumulation of lipofuscin granules, lipid peroxidation, and protein oxidation compared to young queens. These results demonstrate that age-related molecules can be used to evaluate aging in the trophocytes and fat cells of queens and to lay the foundation for further study of the mechanisms that delay cellular aging in the trophocytes and fat cells of queens.

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Acknowledgments

This work was supported by CMRPD 190631 grant from Chang Gung Memorial Hospital, Taiwan.

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Authors and Affiliations

  1. Department of Biomedical Sciences, Chang Gung University, 259, Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, 333, Taiwan

    Chin-Yuan Hsu

  2. Graduate Institute of Basic Medical Science, Chang Gung University, Tao-Yuan, Taiwan

    Yu-Shan Hsieh & Chin-Yuan Hsu

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  1. Yu-Shan Hsieh
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Correspondence to Chin-Yuan Hsu.

Additional information

Modifications des molécules liées à l’âge dans les trophocytes et les cellules adipeuses des reines d’abeilles ( Apis mellifera )

Vieillissement/ trophocyte / cellule adipeuse / reine / abeille

Altersabhängige molekulare Veränderungen im Fettkörper von Königinnen der Honigbiene ( Apis mellifera )

Alterung / Trophozyten / Fettzelle / Königin / Honigbiene

Manuscript editor: David Tarpy

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Hsieh, YS., Hsu, CY. The changes of age-related molecules in the trophocytes and fat cells of queen honeybees (Apis mellifera). Apidologie 42, 728–739 (2011). https://doi.org/10.1007/s13592-011-0085-x

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  • DOI: https://doi.org/10.1007/s13592-011-0085-x

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