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Randomized Controlled Trial: Multimodal Anxiety and Social Skill Intervention for Adolescents with Autism Spectrum Disorder

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Abstract

Anxiety is common among adolescents with autism spectrum disorders (ASD) and may amplify the core social disability, thus necessitating combined treatment approaches. This pilot, randomized controlled trial evaluated the feasibility and preliminary outcomes of the Multimodal Anxiety and Social Skills Intervention (MASSI) program in a sample of 30 adolescents with ASD and anxiety symptoms of moderate or greater severity. The treatment was acceptable to families, subject adherence was high, and therapist fidelity was high. A 16 % improvement in ASD social impairment (within-group effect size = 1.18) was observed on a parent-reported scale. Although anxiety symptoms declined by 26 %, the change was not statistically significant. These findings suggest MASSI is a feasible treatment program and further evaluation is warranted.

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Notes

  1. Participants in both groups (treatment and wait-list) had medication changes during the trial, despite being requested at baseline to delay or minimize medication regimen changes. During the trial, seven of the 15 participants in the MASSI group and nine of the 15 WL participants had medication dosage changes.

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Acknowledgments

This project was supported by a grant from the National Institute of Mental Health [1K01MH079945-01; PI: S. W. White]. We thank the participants in this study, their parents, and their teachers.

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Authors and Affiliations

  1. Department of Psychology, Virginia Polytechnic Institute and State University, 109 Williams Hall (0436), Blacksburg, VA, 24061, USA

    Susan W. White & Thomas Ollendick

  2. Columbia Clinic for Anxiety and Related Disorders, Columbia University, New York, NY, USA

    Anne Marie Albano

  3. Commonwealth Autism Service, Virginia Commonwealth University, Richmond, VA, USA

    Donald Oswald

  4. Autism Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Cynthia Johnson

  5. Yale Child Study Center, School of Nursing, Yale University, New Haven, CT, USA

    Lawrence Scahill

  6. Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA

    Michael A. Southam-Gerow

  7. Department of Pediatrics, Virginia Commonwealth University, Richmond, VA, USA

    Michael A. Southam-Gerow

  8. Department of Statistics, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA

    Inyoung Kim

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  1. Susan W. White
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Correspondence to Susan W. White.

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White, S.W., Ollendick, T., Albano, A.M. et al. Randomized Controlled Trial: Multimodal Anxiety and Social Skill Intervention for Adolescents with Autism Spectrum Disorder. J Autism Dev Disord 43, 382–394 (2013). https://doi.org/10.1007/s10803-012-1577-x

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