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Interleukin 2 receptor subunit alpha (Q21113423)

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mammalian protein found in Homo sapiens

TAC antigen
interleukin-2 receptor subunit alpha
p55
IL-2 receptor subunit alpha
IL2RA
IL-2R subunit alpha
interleukin 2 receptor, alpha
CD25

Language	Label	Description	Also known as
English	Interleukin 2 receptor subunit alpha	mammalian protein found in Homo sapiens	TAC antigen interleukin-2 receptor subunit alpha p55 IL-2 receptor subunit alpha IL2RA IL-2R subunit alpha interleukin 2 receptor, alpha CD25

Statements

1 reference

13 November 2019

UniProt protein ID

interleukin-2 receptor alpha

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01589

Sushi/SCR/CCP superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01589

Sushi/SCR/CCP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

interleukin-2 receptor activity

determination method or standard

4 references

10 September 2018

Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01589&geneProductId=UniProtKB:P01589

determination method or standard

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01589&geneProductId=UniProtKB:P01589

determination method or standard

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01589&geneProductId=UniProtKB:P01589

determination method or standard

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01589&geneProductId=UniProtKB:P01589

determination method or standard

interleukin-2 receptor activity

determination method or standard

5 references

8 April 2019

Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

8 April 2019

Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

integral component of membrane

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

plasma membrane

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

8 April 2019

Interleukin 2 regulates its own receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

8 April 2019

Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

external side of plasma membrane

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

intracellular anatomical structure

determination method or standard

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01589&geneProductId=UniProtKB:P01589

determination method or standard

interleukin-2 receptor complex

determination method or standard

1 reference

8 April 2019

Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

biological process

Notch signaling pathway

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

positive regulation of T cell differentiation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

regulation of T cell tolerance induction

determination method or standard

1 reference

8 April 2019

Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

inflammatory response to antigenic stimulus

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

negative regulation of defense response to virus

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

immune system process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

activation-induced cell death of T cells

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

negative regulation of lymphocyte proliferation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

T cell homeostasis

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

regulation of T cell homeostatic proliferation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

cell surface receptor signaling pathway

determination method or standard

1 reference

8 April 2019

Interleukin 2 regulates its own receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

negative regulation of T cell proliferation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

negative regulation of immune response

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

immune response

determination method or standard

1 reference

8 April 2019

Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

positive regulation of T cell proliferation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

cell population proliferation

determination method or standard

1 reference

1 January 2018

Interleukin 2 regulates its own receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

inflammatory response

determination method or standard

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01589&geneProductId=UniProtKB:P01589

determination method or standard

negative regulation of inflammatory response

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

positive regulation of activated T cell proliferation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

apoptotic process

determination method or standard

1 reference

8 April 2019

Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

regulation of regulatory T cell differentiation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

cytokine-mediated signaling pathway

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

interleukin-2-mediated signaling pathway

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01589

determination method or standard

sushi/SCR/CCP domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01589

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000369293

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000369293

ENSP00000256876

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000256876

ENSP00000369287

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000369287

ENSP00000402024

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000402024

0 references

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(11 entries)

cywiki IL2RA
dewiki CD25
enwiki IL2RA
fawiki IL2RA
frwiki CD25
glwiki CD25
plwiki CD25
ruwiki CD25
trwiki CD25
ukwiki IL2RA
viwiki IL2RA

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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