 | | DRUG: Oxybutynin chloride | |
| Entry |
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| Name |
Oxybutynin chloride (USP);
Oxybutynin hydrochloride (JP18);
Ditropan (TN);
Gelnique (TN) |
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| Product |
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| Generic |
OXYBUTYNIN (A-S Medication Solutions), OXYBUTYNIN (NCS HealthCare of KY), OXYBUTYNIN (NCS HealthCare of KY), OXYBUTYNIN (Zydus Lifesciences Limited), OXYBUTYNIN (Zydus Pharmaceuticals USA), OXYBUTYNIN CHLORIDE (A-S Medication Solutions), OXYBUTYNIN CHLORIDE (A-S Medication Solutions), OXYBUTYNIN CHLORIDE (A-S Medication Solutions), OXYBUTYNIN CHLORIDE (A-S Medication Solutions), OXYBUTYNIN CHLORIDE (A-S Medication Solutions), OXYBUTYNIN CHLORIDE (A-S Medication Solutions), OXYBUTYNIN CHLORIDE (A-S Medication Solutions), OXYBUTYNIN CHLORIDE (A-S Medication Solutions), OXYBUTYNIN CHLORIDE (A-S Medication Solutions), OXYBUTYNIN CHLORIDE (A-S Medication Solutions), OXYBUTYNIN CHLORIDE (ANI Pharmaceuticals), OXYBUTYNIN CHLORIDE (Accord Healthcare), OXYBUTYNIN CHLORIDE (Advagen Pharma Limited), OXYBUTYNIN CHLORIDE (Ajanta Pharma USA), OXYBUTYNIN CHLORIDE (American Health Packaging), OXYBUTYNIN CHLORIDE (American Health Packaging), OXYBUTYNIN CHLORIDE (Amneal Pharmaceuticals LLC), OXYBUTYNIN CHLORIDE (Aphena Pharma Solutions - Tennessee), OXYBUTYNIN CHLORIDE (Aphena Pharma Solutions - Tennessee), OXYBUTYNIN CHLORIDE (Aphena Pharma Solutions - Tennessee), OXYBUTYNIN CHLORIDE (Aphena Pharma Solutions - Tennessee), OXYBUTYNIN CHLORIDE (Aphena Pharma Solutions - Tennessee), OXYBUTYNIN CHLORIDE (Aphena Pharma Solutions - Tennessee), OXYBUTYNIN CHLORIDE (Aphena Pharma Solutions - Tennessee), OXYBUTYNIN CHLORIDE (AvKARE), OXYBUTYNIN CHLORIDE (AvKARE), OXYBUTYNIN CHLORIDE (AvPAK), OXYBUTYNIN CHLORIDE (Bionpharma), OXYBUTYNIN CHLORIDE (Bryant Ranch Prepack), OXYBUTYNIN CHLORIDE (Bryant Ranch Prepack), OXYBUTYNIN CHLORIDE (Bryant Ranch Prepack), OXYBUTYNIN CHLORIDE (Bryant Ranch Prepack), OXYBUTYNIN CHLORIDE (Bryant Ranch Prepack), OXYBUTYNIN CHLORIDE (Bryant Ranch Prepack), OXYBUTYNIN CHLORIDE (Bryant Ranch Prepack), OXYBUTYNIN CHLORIDE (Cardinal Health 107), OXYBUTYNIN CHLORIDE (Chartwell RX), OXYBUTYNIN CHLORIDE (Chartwell RX), OXYBUTYNIN CHLORIDE (DIRECT RX), OXYBUTYNIN CHLORIDE (Drug Ocean LLC), OXYBUTYNIN CHLORIDE (Golden State Medical Supply), OXYBUTYNIN CHLORIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), OXYBUTYNIN CHLORIDE (KVK-Tech), OXYBUTYNIN CHLORIDE (Lannett Company), OXYBUTYNIN CHLORIDE (Lannett Company), OXYBUTYNIN CHLORIDE (Leading Pharma), OXYBUTYNIN CHLORIDE (Major Pharmaceuticals), OXYBUTYNIN CHLORIDE (Major Pharmaceuticals), OXYBUTYNIN CHLORIDE (McKesson Corporation dba SKY Packaging), OXYBUTYNIN CHLORIDE (NCS HealthCare of KY), OXYBUTYNIN CHLORIDE (Northwind Pharmaceuticals), OXYBUTYNIN CHLORIDE (Northwind Pharmaceuticals), OXYBUTYNIN CHLORIDE (Northwind Pharmaceuticals), OXYBUTYNIN CHLORIDE (NuCare Pharmaceuticals), OXYBUTYNIN CHLORIDE (NuCare Pharmaceuticals), OXYBUTYNIN CHLORIDE (PD-Rx Pharmaceuticals), OXYBUTYNIN CHLORIDE (PD-Rx Pharmaceuticals), OXYBUTYNIN CHLORIDE (PD-Rx Pharmaceuticals), OXYBUTYNIN CHLORIDE (PD-Rx Pharmaceuticals), OXYBUTYNIN CHLORIDE (PD-Rx Pharmaceuticals), OXYBUTYNIN CHLORIDE (PD-Rx Pharmaceuticals), OXYBUTYNIN CHLORIDE (Preferred Pharmaceuticals), OXYBUTYNIN CHLORIDE (Proficient Rx LP), OXYBUTYNIN CHLORIDE (Proficient Rx LP), OXYBUTYNIN CHLORIDE (Proficient Rx LP), OXYBUTYNIN CHLORIDE (REMEDYREPACK), OXYBUTYNIN CHLORIDE (RISING PHARMA HOLDINGS), OXYBUTYNIN CHLORIDE (Redpharm Drug), OXYBUTYNIN CHLORIDE (Rising Pharma Holdings), OXYBUTYNIN CHLORIDE (Strides Pharma Science Limited), OXYBUTYNIN CHLORIDE (Teva Pharmaceuticals USA), OXYBUTYNIN CHLORIDE (TruPharma LLC), OXYBUTYNIN CHLORIDE (Upsher-Smith Laboratories), OXYBUTYNIN CHLORIDE (direct rx) |
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| Formula |
C22H31NO3. HCl
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| Exact mass |
393.2071
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| Mol weight |
393.95
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG02925 CYP3A5 substrate
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| Remark |
| Product (DG00478): | D00465<US> D00722<JP/US> |
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| Efficacy |
Antipollakisuria, Overactive bladder agent, Muscarinic acetylcholine receptor antagonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Metabolism |
Enzyme: CYP3A4 [HSA: 1576], CYP3A5 [HSA: 1577]
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G04 UROLOGICALS
G04B UROLOGICALS
G04BD Drugs for urinary frequency and incontinence
G04BD04 Oxybutynin
D00722 Oxybutynin chloride (USP) <JP/US>
USP drug classification [BR:br08302]
Genitourinary Agents
Antispasmodics, Urinary
Cholinergic Muscarinic Antagonists
Oxybutynin
D00722 Oxybutynin chloride (USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
125 Diaphoretics, anhidrotics
1259 Others
D00722 Oxybutynin chloride (USP); Oxybutynin hydrochloride (JP18)
2 Agents affecting individual organs
25 Urogenital and anal organ agents
259 Miscellaneous
2590 Miscellaneous
D00722 Oxybutynin chloride (USP); Oxybutynin hydrochloride (JP18)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00478 Oxybutynin
D00722 Oxybutynin chloride
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00478 Oxybutynin
D00722 Oxybutynin chloride
DG02925 CYP3A5 substrate
DG00478 Oxybutynin
D00722 Oxybutynin chloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00722 Oxybutynin chloride (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00722 Oxybutynin hydrochloride
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00722
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00478 Oxybutynin
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00478 Oxybutynin
DG02925 CYP3A5 substrate
DG00478 Oxybutynin
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| Other DBs |
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| KCF data |
ATOM 27
1 X Cl 40.2271 -21.8179
2 C3b C 28.3117 -21.2592
3 C1b C 29.5266 -21.9607
4 O7a O 30.7417 -21.2592
5 C7a C 31.9567 -21.9607
6 C1d C 33.1717 -21.2592
7 C8y C 34.3868 -21.9607
8 C8x C 35.6018 -21.2592
9 C8x C 36.8167 -21.9607
10 C8x C 34.3868 -23.3637
11 C8x C 35.6018 -24.0652
12 C8x C 36.8167 -23.3637
13 C1y C 33.1717 -19.8562
14 C1x C 34.3718 -19.1632
15 C1x C 34.3717 -17.7602
16 C1x C 33.1567 -17.0588
17 C1x C 31.9565 -17.7518
18 C1x C 31.9566 -19.1548
19 O1a O 34.3868 -20.5577
20 O6a O 31.9567 -23.3637
21 C3b C 27.0967 -20.5577
22 C1b C 25.8816 -19.8562
23 N1c N 24.6479 -20.5687
24 C1b C 23.4400 -19.8715
25 C1b C 24.6482 -21.9606
26 C1a C 22.2552 -20.5558
27 C1a C 23.4450 -22.6556
BOND 27
1 2 3 1
2 3 4 1
3 4 5 1
4 5 6 1
5 6 7 1
6 7 8 1
7 8 9 2
8 7 10 2
9 10 11 1
10 11 12 2
11 9 12 1
12 6 13 1
13 13 14 1
14 14 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 13 18 1
19 6 19 1
20 5 20 2
21 2 21 3
22 21 22 1
23 22 23 1
24 23 24 1
25 23 25 1
26 24 26 1
27 25 27 1
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