| Entry |
|
|---|
| Name |
Oxybutynin (USAN/INN);
Anturol (TN);
Oxytrol (TN) |
|---|
| Product |
|
|---|
| Formula |
C22H31NO3
|
|---|
| Exact mass |
357.2304
|
|---|
| Mol weight |
357.49
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG02925 CYP3A5 substrate
|
|---|
| Remark |
| Product (DG00478): | D00465<US> D00722<JP/US> |
|
|---|
| Efficacy |
Antipollakisuria, Overactive bladder agent, Muscarinic acetylcholine receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
Enzyme: CYP3A4 [HSA: 1576], CYP3A5 [HSA: 1577]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G04 UROLOGICALS
G04B UROLOGICALS
G04BD Drugs for urinary frequency and incontinence
G04BD04 Oxybutynin
D00465 Oxybutynin (USAN/INN) <US>
USP drug classification [BR:br08302]
Genitourinary Agents
Antispasmodics, Urinary
Cholinergic Muscarinic Antagonists
Oxybutynin
D00465 Oxybutynin (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00478 Oxybutynin
D00465 Oxybutynin
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00478 Oxybutynin
D00465 Oxybutynin
DG02925 CYP3A5 substrate
DG00478 Oxybutynin
D00465 Oxybutynin
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00465 Oxybutynin (USAN/INN) <US>
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D00465
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00465
Rx-to-OTC switch list in the USA [br08315.html]
D00465
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00478 Oxybutynin
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00478 Oxybutynin
DG02925 CYP3A5 substrate
DG00478 Oxybutynin
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 26
1 C3b C 14.7700 -23.0300
2 C1b C 15.9824 -23.7300
3 O7a O 17.1949 -23.0300
4 C7a C 18.4073 -23.7300
5 C1d C 19.6197 -23.0300
6 C8y C 20.8322 -23.7300
7 C8x C 22.0446 -23.0300
8 C8x C 23.2570 -23.7300
9 C8x C 20.8322 -25.1300
10 C8x C 22.0446 -25.8300
11 C8x C 23.2570 -25.1300
12 C1y C 19.6197 -21.6300
13 C1x C 20.8173 -20.9385
14 C1x C 20.8172 -19.5385
15 C1x C 19.6047 -18.8386
16 C1x C 18.4071 -19.5301
17 C1x C 18.4072 -20.9301
18 O1a O 20.8322 -22.3300
19 O6a O 18.4073 -25.1300
20 C3b C 13.5576 -22.3300
21 C1b C 12.3451 -21.6300
22 N1c N 11.1140 -22.3410
23 C1b C 9.9088 -21.6453
24 C1b C 11.1143 -23.7299
25 C1a C 8.7265 -22.3281
26 C1a C 9.9138 -24.4234
BOND 27
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 6 7 1
7 7 8 2
8 6 9 2
9 9 10 1
10 10 11 2
11 8 11 1
12 5 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 12 17 1
19 5 18 1
20 4 19 2
21 1 20 3
22 20 21 1
23 21 22 1
24 22 23 1
25 22 24 1
26 23 25 1
27 24 26 1
|
|---|