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- Pathogenomics is a field which uses high-throughput screening technology and bioinformatics to study encoded microbe resistance, as well as virulence factors (VFs), which enable a microorganism to infect a host and possibly cause disease. This includes studying genomes of pathogens which cannot be cultured outside of a host. In the past, researchers and medical professionals found it difficult to study and understand pathogenic traits of infectious organisms. With newer technology, pathogen genomes can be identified and sequenced in a much shorter time and at a lower cost, thus improving the ability to diagnose, treat, and even predict and prevent pathogenic infections and disease. It has also allowed researchers to better understand genome evolution events - gene loss, gain, duplication, rearrangement - and how those events impact pathogen resistance and ability to cause disease. This influx of information has created a need for bioinformatics tools and databases to analyze and make the vast amounts of data accessible to researchers, and it has raised ethical questions about the wisdom of reconstructing previously extinct and deadly pathogens in order to better understand virulence. (en)
- La Patogenomica è lo studio che usa i dat raccolti dalla genomica e metagenomica, attraverso il sequenziamento o i microarray di DNA, per capire la diversità microbica e le interazioni di un microbo coinvolto nello stato di malattina.La maggior parte delle ricerche di Patogenomica si occupa di agenti patogeni che colpiscono la salute umana; tuttavia, esistono studi anche per i vegetali e gli animali. (it)
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- La Patogenomica è lo studio che usa i dat raccolti dalla genomica e metagenomica, attraverso il sequenziamento o i microarray di DNA, per capire la diversità microbica e le interazioni di un microbo coinvolto nello stato di malattina.La maggior parte delle ricerche di Patogenomica si occupa di agenti patogeni che colpiscono la salute umana; tuttavia, esistono studi anche per i vegetali e gli animali. (it)
- Pathogenomics is a field which uses high-throughput screening technology and bioinformatics to study encoded microbe resistance, as well as virulence factors (VFs), which enable a microorganism to infect a host and possibly cause disease. This includes studying genomes of pathogens which cannot be cultured outside of a host. In the past, researchers and medical professionals found it difficult to study and understand pathogenic traits of infectious organisms. With newer technology, pathogen genomes can be identified and sequenced in a much shorter time and at a lower cost, thus improving the ability to diagnose, treat, and even predict and prevent pathogenic infections and disease. It has also allowed researchers to better understand genome evolution events - gene loss, gain, duplication, (en)
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- Patogenomica (it)
- Pathogenomics (en)
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