NLK (kinaza)
| Nemo-slična kinaza | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | NLK; DKFZp761G1211; FLJ21033 | ||||||||||
| Vanjski ID | OMIM: 609476 HomoloGene: 88836 GeneCards: NLK Gene | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 51701 | n/a | |||||||||
| Ensembl | ENSG00000087095 | n/a | |||||||||
| UniProt | Q9UBE8 | n/a | |||||||||
| RefSeq (mRNA) | NM_016231 | n/a | |||||||||
| RefSeq (protein) | NP_057315 | n/a | |||||||||
| Lokacija (UCSC) |
Chr 17: 23.39 - 23.55 Mb | n/a | |||||||||
| PubMed pretraga | [1] | n/a | |||||||||
Serin/treonin protein kinaza NLK je enzim koji je kod ljudi kodiran NLK genom.[1][2][3]
Reference
[уреди | уреди извор]- ^ Brott BK, Pinsky BA, Erikson RL (1998). „Nlk is a murine protein kinase related to Erk/MAP kinases and localized in the nucleus”. Proc Natl Acad Sci U S A. 95 (3): 963—8. PMC 18639
. PMID 9448268. doi:10.1073/pnas.95.3.963.
- ^ Kehrer-Sawatzki H, Moschgath E, Maier C, Legius E, Elgar G, Krone W (2000). „Characterization of the Fugu rubripes NLK and FN5 genes flanking the NF1 (Neurofibromatosis type 1) gene in the 5' direction and mapping of the human counterparts”. Gene. 251 (1): 63—71. PMID 10863097. doi:10.1016/S0378-1119(00)00188-8.
- ^ „Entrez Gene: NLK nemo-like kinase”.
Literatura
[уреди | уреди извор]- Bonaldo MF, Lennon G, Soares MB (1997). „Normalization and subtraction: two approaches to facilitate gene discovery.”. Genome Res. 6 (9): 791—806. PMID 8889548. doi:10.1101/gr.6.9.791.
- Volorio S; Simon G; Repetto M; et al. (1999). „Sequencing analysis of forty-eight human image cDNA clones similar to Drosophila mutant protein.”. DNA Seq. 9 (5-6): 307—15. PMID 10524757. doi:10.3109/10425179809008469.
- Kortenjann M, Wehrle C, Nehls MC, Boehm T (2002). „Only one nemo-like kinase gene homologue in invertebrate and mammalian genomes.”. Gene. 278 (1-2): 161—5. PMID 11707333. doi:10.1016/S0378-1119(01)00710-7.
- Wistow G; Bernstein SL; Wyatt MK; et al. (2002). „Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts.”. Mol. Vis. 8: 196—204. PMID 12107411.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241
- Ishitani T; Kishida S; Hyodo-Miura J; et al. (2003). „The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling.”. Mol. Cell. Biol. 23 (1): 131—9. PMC 140665
- Ishitani T, Ninomiya-Tsuji J, Matsumoto K (2003). „Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling.”. Mol. Cell. Biol. 23 (4): 1379—89. PMC 141159
- Yasuda J; Tsuchiya A; Yamada T; et al. (2003). „Nemo-like kinase induces apoptosis in DLD-1 human colon cancer cells.”. Biochem. Biophys. Res. Commun. 308 (2): 227—33. PMID 12901858. doi:10.1016/S0006-291X(03)01343-3.
- Yasuda J; Yokoo H; Yamada T; et al. (2004). „Nemo-like kinase suppresses a wide range of transcription factors, including nuclear factor-kappaB.”. Cancer Sci. 95 (1): 52—7. PMID 14720327. doi:10.1111/j.1349-7006.2004.tb03170.x.
- Smit L; Baas A; Kuipers J; et al. (2004). „Wnt activates the Tak1/Nemo-like kinase pathway.”. J. Biol. Chem. 279 (17): 17232—40. PMID 14960582. doi:10.1074/jbc.M307801200.
- Kanei-Ishii C; Ninomiya-Tsuji J; Tanikawa J; et al. (2004). „Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK.”. Genes Dev. 18 (7): 816—29. PMC 387421
- Kanei-Ishii C; Nomura T; Tanikawa J; et al. (2004). „Differential sensitivity of v-Myb and c-Myb to Wnt-1-induced protein degradation.”. J. Biol. Chem. 279 (43): 44582—9. PMID 15308626. doi:10.1074/jbc.M407831200.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928
- Kojima H; Sasaki T; Ishitani T; et al. (2005). „STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation.”. Proc. Natl. Acad. Sci. U.S.A. 102 (12): 4524—9. PMC 555521
- Kimura K; Wakamatsu A; Suzuki Y; et al. (2006). „Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.”. Genome Res. 16 (1): 55—65. PMC 1356129
- Lim J; Hao T; Shaw C; et al. (2006). „A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.”. Cell. 125 (4): 801—14. PMID 16713569. doi:10.1016/j.cell.2006.03.032.
- Gohda J; Irisawa M; Tanaka Y; et al. (2007). „HTLV-1 Tax-induced NFkappaB activation is independent of Lys-63-linked-type polyubiquitination.”. Biochem. Biophys. Res. Commun. 357 (1): 225—30. PMID 17418100. doi:10.1016/j.bbrc.2007.03.125.
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