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Apparent fertility of human spermatozoa from the caput epididymidis

J Androl. 1989 Jul-Aug;10(4):263-9. doi: 10.1002/j.1939-4640.1989.tb00098.x.

Abstract

Fifty-one patients with obstructive azoospermia caused by blockage at the caput epididymidis have been followed for 4 years after undergoing "specific tubule" vasoepididymostomy, bypassing the corpus and cauda. The patency rate was 73%, and the pregnancy rate was 31%. There was no correlation between sperm count and pregnancy rate, but there was a strong correlation with sperm motility. With less than 20% motility, only 15% of the patients became pregnant, but with greater than 20% motility postoperatively, 58% became pregnant. If the wife was over 30 years old, only 21% got pregnant. If the wife was under 30, 67% got pregnant. "Redo" cases were just as likely to succeed as "first-time" attempts. In the "patent" cases, 43% of patients with spermatozoa that never reached or traversed the corpus or cauda epididymidis produced a pregnancy. Spermatozoa from the proximal caput produced a 33% pregnancy rate, whereas spermatozoa from the distal caput produced a 50% pregnancy rate. One-half of the pregnancies occurred more than 2 years postoperatively.

MeSH terms

  • Epididymis / cytology
  • Epididymis / physiology*
  • Epididymis / surgery
  • Fertility*
  • Humans
  • Infertility, Male / pathology
  • Infertility, Male / physiopathology
  • Male
  • Oligospermia / pathology
  • Oligospermia / physiopathology
  • Sperm Motility
  • Spermatozoa / cytology
  • Spermatozoa / physiology*
  • Vasectomy / methods