Abstract
Morin is a natural polyphenol, originally isolated from members of the Moraceae family that can be extracted from leaves, fruits, stems and branches of numerous plants. Several evidence have demonstrated that Morin could have a beneficial effect on several human diseases. In fact, Morin exerts antioxidant, antidiabetic, anti-inflammatory, antitumoral, antihypertensive, antibacterial, hypouricemic, and neuroprotective effects, by modulating the activity of many enzymes. In some cases, Morin shows a systemic protective action, reducing negative side effects of several drugs, without interfering with their functions. In addition, in vitro and in vivo studies demonstrated that Morin exhibits very low toxicity levels and its chronic administration is well tolerated. All these findings suggest that Morin could be used, either alone or in combination with other drugs, to prevent many human pathologies.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / metabolism
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Anti-Bacterial Agents / pharmacology
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Anti-Inflammatory Agents, Non-Steroidal / chemistry
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Anti-Inflammatory Agents, Non-Steroidal / metabolism
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Anti-Inflammatory Agents, Non-Steroidal / pharmacology
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Antihypertensive Agents / chemistry
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Antihypertensive Agents / metabolism
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Antihypertensive Agents / pharmacology
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / metabolism
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Antineoplastic Agents / pharmacology
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Antioxidants / chemistry
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Antioxidants / metabolism
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Antioxidants / pharmacology
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Biological Products / chemistry
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Biological Products / metabolism
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Biological Products / pharmacology*
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Flavonoids / chemistry
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Flavonoids / metabolism
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Flavonoids / pharmacology*
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Humans
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Hypoglycemic Agents / chemistry
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Hypoglycemic Agents / metabolism
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Hypoglycemic Agents / pharmacology
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Neuroprotective Agents / chemistry
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Neuroprotective Agents / metabolism
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Neuroprotective Agents / pharmacology
Substances
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Anti-Bacterial Agents
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Anti-Inflammatory Agents, Non-Steroidal
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Antihypertensive Agents
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Antineoplastic Agents
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Antioxidants
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Biological Products
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Flavonoids
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Hypoglycemic Agents
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Neuroprotective Agents
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morin