Abstract
Multi-modal imaging guided photothermal therapy with single-walled carbon nanotubes affords effective destruction of primary tumors together with cancer cells in sentinel lymph nodes. This results in remarkably prolonged mouse survival compared to mice treated by elimination of only the primary tumor by either surgery or conventional photothermal therapy.
Keywords:
biomaterials; photothermal therapy; single-walled carbon nanotubes; tumor metastasis.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cell Line, Tumor
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Combined Modality Therapy
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Disease Models, Animal
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Female
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Hyperthermia, Induced / methods*
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Infrared Rays
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Lung Neoplasms / pathology
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Lung Neoplasms / prevention & control
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Lung Neoplasms / secondary
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Lymph Nodes / pathology*
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Lymphatic Metastasis / pathology
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Lymphatic Metastasis / prevention & control*
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Mammary Neoplasms, Animal
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Mice
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Mice, Inbred BALB C
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Nanotubes, Carbon*
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Neoplasms, Experimental / pathology
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Neoplasms, Experimental / therapy*
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Phototherapy / methods*
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Random Allocation
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Survival Analysis