Motivation: Many drug discovery projects fail because the underlying target is finally found to be undruggable. Progress in structure elucidation of proteins now opens up a route to automatic structure-based target assessment. DoGSiteScorer is a newly developed automatic tool combining pocket prediction, characterization and druggability estimation and is now available through a web server.
Availability: The DoGSiteScorer web server is freely available for academic use at http://dogsite.zbh.uni-hamburg.de
Contact: rarey@zbh.uni-hamburg.de.