Abstract
Six new furostanol saponins (1-6), named fistulosaponins A-F, three known furostanol saponins (7-9), and seven known aromatic compounds were isolated from seeds of Welsh onion (Allium fistulosum). The structures of these compounds were characterized by spectroscopic analyses including 2D NMR spectroscopy, mass spectrometry, and acid hydrolysis. The protective effect of the saponins on hypoxia-induced human umbilical vein endothelial cell injury was evaluated.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology*
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Endothelial Cells / drug effects
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Humans
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Ischemia / drug therapy*
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Onions / chemistry*
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Saponins / chemistry
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Saponins / isolation & purification*
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Saponins / pharmacology*
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Seeds / chemistry
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Sterols / chemistry
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Sterols / isolation & purification*
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Sterols / pharmacology*
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Umbilical Veins / cytology
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Umbilical Veins / drug effects
Substances
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Drugs, Chinese Herbal
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Saponins
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Sterols