In four experiments, we examined whether the phenomenon of illusory conjunctions is constrained by feature similarity. Specifically, are illusory conjunctions more likely to occur between items with similar features than between items with dissimilar features? Feature similarity was manipulated in two dimensions: color and shape. Experiment 1 demonstrated that more illusory conjunctions occur between items with similar colors than between items with dissimilar colors. A similar effect was found for letter similarity in Experiment 2. Experiments 3 and 4 demonstrated that the similarity effect is still obtained for illusory conjunctions even when identification of the relevant features is near perfect. These findings introduce a new constraint in the process of feature integration. Additional implications of the similarity constraint for theories of feature integration are discussed.