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OBJECTIVE: Panic disorder with or without agoraphobia has a chronic relapsing course. Factors associated with poor outcome include early onset of illness and phobic avoidance. Several, but not all, authors have found a worse clinical course for women. ...

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American Journal of PsychiatryRegular Article01 July 1999

Recurrence After Recovery From Major Depressive Disorder During 15 Years of Observational Follow-Up

Timothy I. Mueller, M.D.,
Andrew C. Leon, Ph.D.,
Martin B. Keller, M.D.,
David A. Solomon, M.D.,
Jean Endicott, Ph.D.,
William Coryell, M.D.,
Meredith Warshaw, M.S.S., M.A., and
Jack D. Maser, Ph.D.

OBJECTIVE: The recurrence of an affective disorder in people who initially recover from major depressive disorder was characterized by using the unique longitudinal prospective follow-up data from the National Institute of Mental Health Collaborative ...

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American Journal of PsychiatryRegular Article01 February 2000

Multiple Recurrences of Major Depressive Disorder

David A. Solomon, M.D.,
Martin B. Keller, M.D.,
Andrew C. Leon, Ph.D.,
Timothy I. Mueller, M.D.,
Philip W. Lavori, Ph.D.,
M. Tracie Shea, Ph.D.,
William Coryell, M.D.,
Meredith Warshaw, M.S.S., M.A.,
Carolyn Turvey, Ph.D.,
Jack D. Maser, Ph.D., and
Jean Endicott, Ph.D.

OBJECTIVE: The authors of this study examined multiple recurrences of unipolar major depressive disorder. METHOD: A total of 318 subjects with unipolar major depressive disorder were prospectively followed for 10 years within a multicenter naturalistic ...

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