The Journal of Neuropsychiatry and Clinical Neurosciences
Articles In Advance
Publication date: 04 December 2024
Memory impairments are common chronic and functionally important consequences of traumatic brain injury (TBI). Among patients with persistent verbal memory impairments due to TBI-related cholinergic deficits, donepezil (an acetylcholinesterase inhibitor) ...
https://doi.org/10.1176/appi.neuropsych.20230055Publication date: 04 December 2024
Objective: The purpose of this study was to compare functional vision loss (FVL) among adults and children, including its presentation and the biopsychosocial factors that may contribute to FVL development. Methods: PubMed, Scopus, and PsycInfo databases ...
https://doi.org/10.1176/appi.neuropsych.20240027Publication date: 04 December 2024
https://doi.org/10.1176/appi.neuropsych.20240044Publication date: 19 November 2024
Objective: Apathy is common in Huntington’s disease (HD) and difficult to treat. Multiple recent calls have been made to increase understanding of apathy across the spectrum of HD severity. Functional status is an important outcome in HD trials; however, ...
https://doi.org/10.1176/appi.neuropsych.20230225Publication date: 19 November 2024
https://doi.org/10.1176/appi.neuropsych.20230227Publication date: 19 November 2024
Objective: Research suggests that disrupted interoception contributes to the development and maintenance of functional neurological disorder (FND); however, no functional neuroimaging studies have examined the processing of interoceptive signals in ...
https://doi.org/10.1176/appi.neuropsych.20240070Publication date: 19 November 2024
https://doi.org/10.1176/appi.neuropsych.20240175Publication date: 10 October 2024
Objective: This article describes the design, methods, and participant characteristics of the second phase of the Concussion Assessment, Research, and Education (CARE) Consortium study (“CARE 2.0”) of the effects of concussion and repetitive head impact ...
https://doi.org/10.1176/appi.neuropsych.20240022Publication date: 10 October 2024
Objective: The authors proposed catatonia diagnostic criteria that require the presence of three neuropsychiatric symptom clusters, rated over 24 hours; this system differs from other symptom clustering proposals and is intended to increase diagnostic ...
https://doi.org/10.1176/appi.neuropsych.20230100Publication date: 10 October 2024
Objective: Posttraumatic stress disorder (PTSD) is a highly heterogeneous disorder, which makes it difficult to link clinical phenotypes with biomarkers to improve treatment outcomes. Findings from previous studies suggest that cognitive measures such as ...
https://doi.org/10.1176/appi.neuropsych.20240058Publication date: 10 October 2024
Objective: Functional neurological disorder (FND) is a core neuropsychiatric condition that includes both physical and mental symptoms. Recently, a validated clinical phenotype termed neuroconnective endophenotype (NEP), which includes several physical and ...
https://doi.org/10.1176/appi.neuropsych.20240016Publication date: 22 August 2024
Objective: Responsive and human-centered neurotechnology development requires attention to public perceptions, particularly among groups underserved by existing treatments. Methods: The authors conducted a preregistered nationally representative survey (...
https://doi.org/10.1176/appi.neuropsych.20230190Publication date: 22 August 2024
Objective: Neuropsychiatric symptoms (NPSs) have been linked to cognitive decline. This study explored ethnic differences and the effects of baseline NPSs on incident mild cognitive impairment (MCI) among 386 Hispanic and non-Hispanic participants from the ...
https://doi.org/10.1176/appi.neuropsych.20230180Publication date: 08 August 2024
Objective: The purpose of the present study was to assess the psychiatric manifestations of early to middle stages of fragile X-associated tremor-ataxia syndrome (FXTAS) and their relationship with executive function and FMR1 cytosine-guanine-guanine (CGG) ...
https://doi.org/10.1176/appi.neuropsych.20230215Publication date: 08 August 2024
Objective: Cognitive impairment is a common nonmotor symptom in Parkinson’s disease (PD). Individuals of Latino background are traditionally underrepresented in research on PD. Despite the fact that Latinos comprise 18% of the U.S. population, they ...
https://doi.org/10.1176/appi.neuropsych.20240006Publication date: 08 August 2024
Objectives: Mild traumatic brain injury (mTBI) can lead to psychiatric and somatic symptoms for some patients, including posttraumatic headache (PTH) and depression. This study attempted to further establish the relationship between PTH and depression ...
https://doi.org/10.1176/appi.neuropsych.20230143Publication date: 22 July 2024
Page00Psychotic symptoms frequently occur in idiopathic Parkinson’s disease (PD) and often require treatment with antipsychotic therapy. Most antipsychotics have the potential to worsen the motor symptoms of PD; quetiapine, clozapine, and pimavanserin are ...
https://doi.org/10.1176/appi.neuropsych.20230231Publication date: 22 July 2024
Objective: Neurobehavioral dysregulation (NBD), a core clinical feature of traumatic encephalopathy syndrome, encompasses neuropsychiatric symptoms reported among individuals with a history of repetitive head impact exposure, including contact sport ...
https://doi.org/10.1176/appi.neuropsych.20230133Publication date: 22 July 2024
Objective: Functional neurological disorders (FNDs) are increasingly recognized in the general population and neurology clinics, and there is evidence that patients with neurological disorders are more likely to have a FND. This study was designed to ...
https://doi.org/10.1176/appi.neuropsych.20230126Publication date: 11 July 2024
Objective: Loneliness reportedly increases the risk of dementia, especially Alzheimer’s disease (AD). The authors’ previous study demonstrated associations between loneliness and structural abnormalities observed in early-stage AD. The present study ...
https://doi.org/10.1176/appi.neuropsych.20230167