ZA985018B - 9-oxime erythromycin derivatives. - Google Patents

9-oxime erythromycin derivatives.

Info

Publication number: ZA985018B
Authority: ZA; South Africa
Prior art keywords: erythromycin derivatives; oxime erythromycin; oxime; derivatives; erythromycin
Prior art date: 1997-06-11

Application number

ZA9805018A

Inventor

Yong-Jin Wu

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-11

Filing date

1998-06-10

Publication date

1999-12-10

1998-06-10 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

1999-12-10 Publication of ZA985018B publication Critical patent/ZA985018B/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Epidemiology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

ZA9805018A 1997-06-11 1998-06-10 9-oxime erythromycin derivatives. ZA985018B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US4934997P	1997-06-11	1997-06-11

Publications (1)

Publication Number	Publication Date
ZA985018B true ZA985018B (en)	1999-12-10

Family

ID=21959341

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9805018A ZA985018B (en)	1997-06-11	1998-06-10	9-oxime erythromycin derivatives.

Country Status (31)

Country	Link
EP (1)	EP0988308A1 (en)
JP (1)	JP2000513026A (en)
KR (1)	KR20010013660A (en)
CN (1)	CN1259135A (en)
AP (1)	AP9801253A0 (en)
AR (1)	AR012244A1 (en)
AU (1)	AU7226798A (en)
BG (1)	BG103947A (en)
BR (1)	BR9810021A (en)
CA (1)	CA2293335A1 (en)
CO (1)	CO4940506A1 (en)
CZ (1)	CZ9904388A3 (en)
EA (1)	EA199901016A1 (en)
GT (1)	GT199800074A (en)
HN (1)	HN1998000073A (en)
HR (1)	HRP980316A2 (en)
HU (1)	HUP0002252A3 (en)
ID (1)	ID24529A (en)
IL (1)	IL132767A0 (en)
IS (1)	IS5251A (en)
MA (1)	MA26505A1 (en)
NO (1)	NO996108L (en)
OA (1)	OA11225A (en)
PA (1)	PA8451801A1 (en)
PE (1)	PE79899A1 (en)
PL (1)	PL337606A1 (en)
TN (1)	TNSN98083A1 (en)
TR (1)	TR199902995T2 (en)
TW (1)	TW448174B (en)
WO (1)	WO1998056800A1 (en)
ZA (1)	ZA985018B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HN1998000159A (en) *	1997-10-29	1999-02-09	Monsanto Co	DERIVATIVES OF 9- AMINO - 3 CETO ERITROMICINA
WO2000017218A1 (en)	1998-09-22	2000-03-30	Pfizer Products Inc.	Carbamate and carbazate ketolide antibiotics
FR2786188B1 (en) *	1998-11-24	2002-10-31	Hoechst Marion Roussel Inc	NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
US6258785B1 (en)	1998-12-02	2001-07-10	Pfizer Inc.	Crystalline 9-E-(O-methyl)oxime of 11, 12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)1H-imadazol-1-yl)propyl)hydrazono))-3-oxoerythromycin
EP1298138B1 (en) *	1998-12-10	2006-11-02	Pfizer Products Inc.	Carbamate and Carbazate Ketolide Antibiotics
US6284732B1 (en) *	1998-12-18	2001-09-04	Bio-Rad Laboratories, Inc.	Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases
WO2000063225A2 (en) *	1999-04-16	2000-10-26	Kosan Biosciences, Inc.	Macrolide antiinfective agents
OA11945A (en)	1999-05-24	2006-04-13	Pfizer Prod Inc	13-Methyl erythromycin derivatives.
PT1181300E (en) *	1999-06-07	2004-02-27	Abbott Lab	DERIVATIVES 6-O-CARBAMATE OF CETOLID
ID27331A (en) *	1999-09-29	2001-03-29	Pfizer Prod Inc	MAKING ANTIBIOTIC-ANTIBIOTIC KETOLIDA CARBAMATE
EP1114826A3 (en) *	1999-12-29	2001-10-31	Pfizer Products Inc.	Novel antibacterial and prokinetic macrolides
EP1439186A3 (en) *	1999-12-29	2004-11-03	Pfizer Products Inc.	Intermediates for novel antibacterial and prokinetic macrolides
US6946446B2 (en)	2000-02-24	2005-09-20	Abbott Laboratories	Anti-infective agents useful against multidrug-resistant strains of bacteria
US6403776B1 (en)	2000-07-05	2002-06-11	Pfizer Inc.	Synthesis of carbamate ketolide antibiotics
WO2003090761A1 (en) *	2002-04-25	2003-11-06	Abbott Laboratories	9-oxime macrolide antibacterials
TW200420573A (en)	2002-09-26	2004-10-16	Rib X Pharmaceuticals Inc	Bifunctional heterocyclic compounds and methods of making and using same
US7601695B2 (en) *	2003-03-10	2009-10-13	Optimer Pharmaceuticals, Inc.	Antibacterial agents
CN102816194A (en)	2004-02-27	2012-12-12	瑞伯-X医药品有限公司	Macrocyclic compounds and methods of making and using the same
WO2009055557A1 (en)	2007-10-25	2009-04-30	Cempra Pharmaceuticals, Inc.	Process for the preparation of macrolide antibacterial agents
EP3031460A1 (en)	2008-10-24	2016-06-15	Cempra Pharmaceuticals Inc.	Biodefenses using triazole-containing macrolides
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
EP2475253B1 (en)	2009-09-10	2016-10-26	Cempra Pharmaceuticals, Inc.	Methods for treating malaria, tuberculosis and mac diseases
CN102146085B (en) *	2010-02-09	2014-03-26	北京理工大学	9-oxime-ether ketolide derivative, and preparation method and medical composite thereof
DK2550286T3 (en)	2010-03-22	2016-02-29	Cempra Pharmaceuticals Inc	CRYSTALLINE FORMS OF A MACROLID AND APPLICATIONS THEREOF
US9051346B2 (en)	2010-05-20	2015-06-09	Cempra Pharmaceuticals, Inc.	Process for preparing triazole-containing ketolide antibiotics
KR20180110181A (en)	2010-09-10	2018-10-08	셈프라 파마슈티컬스, 인크.	Hydrogen bond forming fluoro ketolides for treating diseases
MX2014011537A (en)	2012-03-27	2015-02-10	Cempra Pharmaceuticals Inc	Parenteral formulations for administering macrolide antibiotics.
RU2015138796A (en)	2013-03-14	2017-04-19	Семпра Фармасьютикалс, Инк.	METHODS AND COMPOSITIONS FOR TREATMENT OF RESPIRATORY DISEASES
EP2968384A4 (en)	2013-03-15	2017-02-15	Cempra Pharmaceuticals, Inc.	Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL114589A (en) *	1990-11-21	1999-12-22	Roussel Uclaf	Intermediates for the preparation of erythromycin derivatives
US5527780A (en) *	1992-11-05	1996-06-18	Roussel Uclaf	Erythromycin derivatives
FR2718450B1 (en) *	1994-04-08	1997-01-10	Roussel Uclaf	New erythromycin derivatives, their preparation process and their use as drugs.

1998
- 1998-05-15 IL IL13276798A patent/IL132767A0/en unknown
- 1998-05-15 BR BR9810021-1A patent/BR9810021A/en not_active IP Right Cessation
- 1998-05-15 WO PCT/IB1998/000741 patent/WO1998056800A1/en not_active Application Discontinuation
- 1998-05-15 CA CA002293335A patent/CA2293335A1/en not_active Abandoned
- 1998-05-15 HU HU0002252A patent/HUP0002252A3/en unknown
- 1998-05-15 EA EA199901016A patent/EA199901016A1/en unknown
- 1998-05-15 KR KR1019997011672A patent/KR20010013660A/en not_active Application Discontinuation
- 1998-05-15 PL PL98337606A patent/PL337606A1/en unknown
- 1998-05-15 CN CN98805848A patent/CN1259135A/en active Pending
- 1998-05-15 EP EP98919394A patent/EP0988308A1/en not_active Withdrawn
- 1998-05-15 JP JP11501928A patent/JP2000513026A/en active Pending
- 1998-05-15 AU AU72267/98A patent/AU7226798A/en not_active Abandoned
- 1998-05-15 CZ CZ19994388A patent/CZ9904388A3/en unknown
- 1998-05-15 ID IDW991570A patent/ID24529A/en unknown
- 1998-05-15 TR TR1999/02995T patent/TR199902995T2/en unknown
- 1998-05-19 HN HN1998000073A patent/HN1998000073A/en unknown
- 1998-05-21 PA PA19988451801A patent/PA8451801A1/en unknown
- 1998-06-04 AP APAP/P/1998/001253A patent/AP9801253A0/en unknown
- 1998-06-05 GT GT199800074A patent/GT199800074A/en unknown
- 1998-06-08 PE PE1998000470A patent/PE79899A1/en not_active Application Discontinuation
- 1998-06-08 TW TW087109086A patent/TW448174B/en active
- 1998-06-09 AR ARP980102703A patent/AR012244A1/en unknown
- 1998-06-10 TN TNTNSN98083A patent/TNSN98083A1/en unknown
- 1998-06-10 MA MA25105A patent/MA26505A1/en unknown
- 1998-06-10 ZA ZA9805018A patent/ZA985018B/en unknown
- 1998-06-11 HR HR60/049,349A patent/HRP980316A2/en not_active Application Discontinuation
- 1998-06-11 CO CO98033538A patent/CO4940506A1/en unknown
1999
- 1999-11-16 IS IS5251A patent/IS5251A/en unknown
- 1999-12-03 BG BG103947A patent/BG103947A/en unknown
- 1999-12-03 OA OA9900269A patent/OA11225A/en unknown
- 1999-12-10 NO NO996108A patent/NO996108L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
PL337606A1 (en)	2000-08-28
EP0988308A1 (en)	2000-03-29
KR20010013660A (en)	2001-02-26
TW448174B (en)	2001-08-01
TR199902995T2 (en)	2000-02-21
AR012244A1 (en)	2000-09-27
NO996108L (en)	2000-02-10
NO996108D0 (en)	1999-12-10
TNSN98083A1 (en)	2005-03-15
EA199901016A1 (en)	2000-06-26
IL132767A0 (en)	2001-03-19
CZ9904388A3 (en)	2002-10-16
HUP0002252A3 (en)	2002-01-28
PE79899A1 (en)	1999-08-25
CA2293335A1 (en)	1998-12-17
BR9810021A (en)	2000-09-19
HN1998000073A (en)	1999-01-08
PA8451801A1 (en)	2000-05-24
IS5251A (en)	1999-11-16
BG103947A (en)	2000-07-31
HUP0002252A2 (en)	2000-12-28
JP2000513026A (en)	2000-10-03
GT199800074A (en)	1999-11-27
ID24529A (en)	2000-07-20
CN1259135A (en)	2000-07-05
AU7226798A (en)	1998-12-30
MA26505A1 (en)	2004-12-20
WO1998056800A1 (en)	1998-12-17
OA11225A (en)	2003-07-17
HRP980316A2 (en)	1999-04-30
CO4940506A1 (en)	2000-07-24
AP9801253A0 (en)	1999-12-04

Publication	Publication Date	Title
ZA985018B (en)	1999-12-10	9-oxime erythromycin derivatives.
ZA9811940B (en)	2000-06-30	Novel erythromycin derivatives.
ZA9811939B (en)	2000-06-30	Novel macrolides.
PL348333A1 (en)	2002-05-20	Macrolides
AU9277698A (en)	1999-05-17	9-amino-3-keto erythromycin derivatives
ZA985016B (en)	1999-12-10	C-4"-substituted macrolide derivatives.
ZA98986B (en)	1998-08-05	3'-n-oxide,3'-N-dimethylamine, 9-oxime erythromycin A derivatives
ZA200103289B (en)	2002-08-28	Novel macrolide antibiotics.
ZA9710648B (en)	1998-06-23	Erythromycin A derivatives.
IL134220A0 (en)	2001-04-30	6,9-bridged erythromycin derivatives
IL134996A0 (en)	2001-05-20	6,11-bridged erythromycin derivatives
HK1031383A1 (en)	2001-06-15	2-Halo-5-o-substituted ketolide derivatives
ZA200107346B (en)	2002-11-27	Erythromycin derivatives.
ZA989830B (en)	1999-05-04	Erythromycin a derivatives
AU8925398A (en)	1999-03-22	3-descladinose 6-o-substituded erythromycin derivatives
ZA983902B (en)	1999-11-08	Erythromycin derivatives.
EP1044985A4 (en)	2001-04-18	Erythromycin derivatives
ZA981572B (en)	1998-09-01	Erythromycin a derivatives
ZA978546B (en)	1998-04-01	Erythromycin A derivatives.
MXPA99011001A (en)	2003-09-10	Multicyclic erythromycin derivatives.
ZA989848B (en)	1999-04-29	6,11-bridged erythromycin derivatives
SI1027361T1 (en)	2004-02-29	6,11-bridged erythromycin derivatives
SI1015467T1 (en)	2004-06-30	6,9-bridged erythromycin derivatives
GB9700702D0 (en)	1997-03-05	Erythromycin derivatives
SI0966477T1 (en)	2004-02-29	3'-n-oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives