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ZA9710574B - 2-imidazolinylaminobenzothiazole compounds useful as alpha-2 adrenoceptor agonists. - Google Patents

2-imidazolinylaminobenzothiazole compounds useful as alpha-2 adrenoceptor agonists.

Info

Publication number
ZA9710574B
ZA9710574B ZA9710574A ZA9710574A ZA9710574B ZA 9710574 B ZA9710574 B ZA 9710574B ZA 9710574 A ZA9710574 A ZA 9710574A ZA 9710574 A ZA9710574 A ZA 9710574A ZA 9710574 B ZA9710574 B ZA 9710574B
Authority
ZA
South Africa
Prior art keywords
imidazolinylaminobenzothiazole
alpha
compounds useful
adrenoceptor agonists
adrenoceptor
Prior art date
Application number
ZA9710574A
Inventor
Thomas Lee Cupps
Sophie Eva Bogdan
Raymond Todd Henry
Russell James Sheldon
William Lee Seibel
Jeffrey Joseph Ares
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of ZA9710574B publication Critical patent/ZA9710574B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
ZA9710574A 1996-11-25 1997-11-25 2-imidazolinylaminobenzothiazole compounds useful as alpha-2 adrenoceptor agonists. ZA9710574B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3175696P 1996-11-25 1996-11-25

Publications (1)

Publication Number Publication Date
ZA9710574B true ZA9710574B (en) 1998-06-10

Family

ID=21861233

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9710574A ZA9710574B (en) 1996-11-25 1997-11-25 2-imidazolinylaminobenzothiazole compounds useful as alpha-2 adrenoceptor agonists.

Country Status (6)

Country Link
AR (1) AR010644A1 (en)
AU (1) AU5433898A (en)
CO (1) CO4910168A1 (en)
PE (1) PE16199A1 (en)
WO (1) WO1998023612A1 (en)
ZA (1) ZA9710574B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5677321A (en) 1996-02-29 1997-10-14 Synaptic Pharmaceutical Corporation 5- and 6-(2-imidazolin-2-ylamino) and -(2-thiazolin-2-ylamino)-benzothiazoles as alpha-2 adrenergic ligands
CA2419653A1 (en) * 2000-09-08 2002-03-14 Warner-Lambert Company Prevention of acute sinusitis and sinus attack
US8555875B2 (en) 2008-12-23 2013-10-15 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
BR112014001951A2 (en) * 2011-07-25 2017-02-21 Allergan Inc n- (imidazolidin-2-ylidene) heterocyclopenta [b] pyridine derivatives as alpha 2 adrenergic receptor modulators
CN112538074A (en) * 2020-12-24 2021-03-23 艾希尔（深圳）药物研发有限公司 Preparation method of debrominated impurities of brimonidine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754832A (en) * 1969-08-14 1971-02-15 Beecham Group Ltd IMINAZOLINES
BE795970A (en) * 1972-02-29 1973-08-27 Pfizer NEW DERIVATIVES OF QUINOLEINE, QUINOXALINE AND QUINAZOLINE ER PHARMACEUTICAL COMPOSITION CONTAINING THEM
FR2521140A1 (en) * 1982-02-05 1983-08-12 Synthelabo IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
US5180721A (en) * 1989-05-22 1993-01-19 Allergan, Inc. Combinations of selective alpha-adrenergic agonists and antagonists useful in lowering intraocular pressure
US5021410A (en) * 1989-05-22 1991-06-04 Allergan, Inc. Combinations of selective alpha-adrenergic agonists and antagonists useful in lowering intraocular pressure
US5091528A (en) * 1990-09-12 1992-02-25 Allergan, Inc. 6- or 7- (2-imino-2-imidazolidine)-1,4-benzoxazines as α adrenergic agents
US5677321A (en) * 1996-02-29 1997-10-14 Synaptic Pharmaceutical Corporation 5- and 6-(2-imidazolin-2-ylamino) and -(2-thiazolin-2-ylamino)-benzothiazoles as alpha-2 adrenergic ligands

Also Published As

Publication number Publication date
PE16199A1 (en) 1999-03-12
AU5433898A (en) 1998-06-22
WO1998023612A1 (en) 1998-06-04
AR010644A1 (en) 2000-06-28
CO4910168A1 (en) 2000-04-24

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