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ZA929390B - The use of D-fenfluramine and fenfluramine compounds in the treatment of hypertension in insulin-resistant subjects. - Google Patents

The use of D-fenfluramine and fenfluramine compounds in the treatment of hypertension in insulin-resistant subjects.

Info

Publication number
ZA929390B
ZA929390B ZA929390A ZA929390A ZA929390B ZA 929390 B ZA929390 B ZA 929390B ZA 929390 A ZA929390 A ZA 929390A ZA 929390 A ZA929390 A ZA 929390A ZA 929390 B ZA929390 B ZA 929390B
Authority
ZA
South Africa
Prior art keywords
fenfluramine
hypertension
insulin
treatment
compounds
Prior art date
Application number
ZA929390A
Inventor
Michel Wierzbicki
Pierre Hugon
Jacques Duhault
Joseph Espinal
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA929390B publication Critical patent/ZA929390B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA929390A 1991-12-06 1992-12-03 The use of D-fenfluramine and fenfluramine compounds in the treatment of hypertension in insulin-resistant subjects. ZA929390B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9115122A FR2684552B1 (en) 1991-12-06 1991-12-06 USE OF D-FENFLURAMINE AND FENFLURAMINE DERIVATIVES IN THE TREATMENT OF HYPERTENSION IN INSULIN RESISTANT SUBJECTS.

Publications (1)

Publication Number Publication Date
ZA929390B true ZA929390B (en) 1993-06-07

Family

ID=9419739

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA929390A ZA929390B (en) 1991-12-06 1992-12-03 The use of D-fenfluramine and fenfluramine compounds in the treatment of hypertension in insulin-resistant subjects.

Country Status (6)

Country Link
EP (1) EP0545805A1 (en)
JP (1) JPH07103021B2 (en)
AU (1) AU657015B2 (en)
CA (1) CA2084641A1 (en)
FR (1) FR2684552B1 (en)
ZA (1) ZA929390B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9549909B2 (en) 2013-05-03 2017-01-24 The Katholieke Universiteit Leuven Method for the treatment of dravet syndrome
US20170174614A1 (en) 2015-12-22 2017-06-22 Zogenix International Limited Metabolism resistant fenfluramine analogs and methods of using the same
CA3007286A1 (en) 2015-12-22 2017-06-29 Zogenix International Limited Fenfluramine compositions and methods of preparing the same
MX2019001799A (en) 2016-08-24 2019-06-13 Zogenix International Ltd Formulation for inhibiting formation of 5-ht 2b agonists and methods of using same.
US10682317B2 (en) 2017-09-26 2020-06-16 Zogenix International Limited Ketogenic diet compatible fenfluramine formulation
WO2019216919A1 (en) 2018-05-11 2019-11-14 Zogenix International Limited Compositions and methods for treating seizure-induced sudden death
EP3806835A1 (en) 2018-06-14 2021-04-21 Zogenix International Limited Compositions and methods for treating respiratory depression with fenfluramine
US11612574B2 (en) 2020-07-17 2023-03-28 Zogenix International Limited Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452815A (en) * 1980-06-16 1984-06-05 Massachusetts Institute Of Technology Method of utilizing d,l-fenfluramine for modifying feeding behavior
US4309445A (en) * 1980-06-16 1982-01-05 Massachusetts Institute Of Technology d-Fenfluramine for modifying feeding behavior
FR2502952A1 (en) * 1981-04-07 1982-10-08 Science Union & Cie NEW BENFLUOREX HYDROCHLORIDE DRUG FOR THE TREATMENT OF DIABETES
US4649161A (en) * 1986-06-16 1987-03-10 Massachusetts Institute Of Technology Method for treating depression with d-fenfluramine

Also Published As

Publication number Publication date
AU657015B2 (en) 1995-02-23
EP0545805A1 (en) 1993-06-09
AU2992492A (en) 1993-06-10
FR2684552A1 (en) 1993-06-11
FR2684552B1 (en) 1995-04-28
JPH05310564A (en) 1993-11-22
JPH07103021B2 (en) 1995-11-08
CA2084641A1 (en) 1993-06-07

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