ZA917766B - Hybrid growth factors. - Google Patents

Hybrid growth factors.

Info

Publication number: ZA917766B
Authority: ZA; South Africa
Prior art keywords: growth factors; hybrid growth; hybrid; factors; growth
Prior art date: 1990-09-28

Application number

ZA917766A

Other languages

English (en)

Inventor

Jonathan I Rosen

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-28

Filing date

1991-09-27

Publication date

1993-03-29

1991-09-27 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

1993-03-29 Publication of ZA917766B publication Critical patent/ZA917766B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5403—IL-3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Hematology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)

ZA917766A 1990-09-28 1991-09-27 Hybrid growth factors. ZA917766B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US58995890A	1990-09-28	1990-09-28

Publications (1)

Publication Number	Publication Date
ZA917766B true ZA917766B (en)	1993-03-29

Family

ID=24360286

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA917766A ZA917766B (en)	1990-09-28	1991-09-27	Hybrid growth factors.

Country Status (8)

Country	Link
EP (1)	EP0503050A4 (fr)
JP (1)	JPH05502463A (fr)
AU (2)	AU8735991A (fr)
CA (1)	CA2069746A1 (fr)
IE (1)	IE913426A1 (fr)
PT (1)	PT99107A (fr)
WO (1)	WO1992006116A1 (fr)
ZA (1)	ZA917766B (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5718893A (en) *	1984-04-15	1998-02-17	Foster; Preston F.	Use of G-CSF to reduce acute rejection
AU651152B2 (en) *	1990-08-29	1994-07-14	Genetics Institute, Llc	Multidomain hematopoiesis stimulators
US6057133A (en) *	1992-11-24	2000-05-02	G. D. Searle	Multivariant human IL-3 fusion proteins and their recombinant production
US5738849A (en) *	1992-11-24	1998-04-14	G. D. Searle & Co.	Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
PT670898E (pt) *	1992-11-24	2004-02-27	Searle & Co	Polipeptidos de multiplas mutacoes de interleucina-3 (il-3)
US6153183A (en)	1992-11-24	2000-11-28	G. D. Searle & Company	Co-administration of interleukin-3 mutant polypeptides with CSF's or cytokines for multi-lineage hematopoietic cell production
US5501962A (en) *	1993-06-21	1996-03-26	G. D. Searle & Co.	Interleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the same
WO1995028427A1 (fr) *	1994-04-15	1995-10-26	Imclone Systems Incorporated	Lymphokine chimere composee de l'interleukine 3 et d'une muteine de l'interleukine 6
US5536495A (en) *	1994-04-15	1996-07-16	Foster; Preston F.	Use of G-CSF to reduce acute rejection
ITFI940106A1 (it) *	1994-05-27	1995-11-27	Menarini Ricerche Sud Spa	Molecola ibrida di formula gm-csf-l-epo o epo-l-gm-csf per la stimolaz ione eritropoietica
IT1271688B (it) *	1994-08-04	1997-06-04	Menarini Ricerche Sud Spa	Molecole ibride per il trattamento antitumorale loro preparazione e loro uso in composizioni farmaceutiche
AU705064B2 (en) *	1995-04-26	1999-05-13	Kyowa Hakko Kogyo Co. Ltd.	Novel polypeptides
US6066318A (en)	1995-10-05	2000-05-23	G.D. Searle & Co.	Multi-functional hematopoietic fusion proteins between sequence rearranged C-MPL receptor agonists and other hematopoietic factors
ATE209354T1 (de) *	1996-09-20	2001-12-15	Ortho Mcneil Pharm Inc	Methode zur in vitro-bestimmung der bioaktivität von erythropoietin
US6967092B1 (en)	1996-10-25	2005-11-22	Mc Kearn John P	Multi-functional chimeric hematopoietic receptor agonists
CZ130199A3 (cs) *	1996-10-25	1999-07-14	G. D. Searle & Co.	Cirkulárně permutovaní agonisté receptoru erythropoietinu
KR100497423B1 (ko) *	1996-10-25	2005-07-07	지.디. 썰 엘엘씨	다기능 키메라 조혈 수용체 아고니스트
US6187564B1 (en) *	1997-07-10	2001-02-13	Beth Israel Deaconess Medical Center	DNA encoding erythropoietin multimers having modified 5′ and 3′ sequences and its use to prepare EPO therapeutics
US6165476A (en) *	1997-07-10	2000-12-26	Beth Israel Deaconess Medical Center	Fusion proteins with an immunoglobulin hinge region linker
ES2208798T3 (es) *	1997-09-01	2004-06-16	Aventis Pharma Deutschland Gmbh	Eritropoyetina humana recombinante con un perfil de glicosilacion ventajoso.
AU2866599A (en) *	1998-02-17	1999-08-30	Hyseq, Inc.	A novel interleukin-3 and uses thereof
BR9917606A (pt) *	1998-11-06	2002-12-31	Bio Sidus S A	Procedimento para a purificação de eritropoetina humana recombinante a partir de sobrenadantes de cultivo de células e eritropoetina humana recombinante obtida com tal procedimento
DE60109625T3 (de)	2000-05-15	2017-08-03	F. Hoffmann-La Roche Ag	Flüssige arzneizubereitung enthaltend ein erythropoietin derivat
US7220407B2 (en)	2003-10-27	2007-05-22	Amgen Inc.	G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
CA2586365A1 (fr)	2004-11-05	2006-05-26	Northwestern University	Utilisation de scf et de scf dans le traitement de l'ischemie cerebrale et des troubles neurologiques
PE20130557A1 (es)	2010-03-04	2013-05-19	Pfenex Inc	Metodo para producir proteinas de interferon recombinantes solubles sin desnaturalizacion
EP2552949B1 (fr)	2010-04-01	2016-08-17	Pfenex Inc.	Procédés pour la production de g-csf dans une cellule hôte de pseudomonas
TWI502016B (zh)	2012-07-31	2015-10-01	Asahi Kasei E Materials Corp	Epoxy resin compositions, epoxy resins and hardened products
LT6161B (lt)	2013-09-27	2015-06-25	Uab Profarma	Granuliocitų kolonijas stimuliuojančio faktoriaus sulieti baltymai su kitais augimo faktoriais, optimaliai su kamieninių ląstelių faktoriumi, ir jų gavimo būdas

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES522315A0 (es) *	1982-05-12	1984-08-16	Harvard College	Un procedimiento para obtener una proteina hibrida.
US4935352A (en) *	1985-10-21	1990-06-19	Takeda Chemical Industries, Ltd.	Expression vector for animal cell line and use thereof
US4935233A (en) *	1985-12-02	1990-06-19	G. D. Searle And Company	Covalently linked polypeptide cell modulators
CA1339346C (fr) *	1986-08-01	1997-08-26	Ian Allister Ramshaw	Vaccin chimerique recombinant
JPH04500508A (ja) *	1988-07-20	1992-01-30	イミュネックス・コーポレーション	非グリコシル化　ヒト　インターロイキン―３　組成物
US5166322A (en) *	1989-04-21	1992-11-24	Genetics Institute	Cysteine added variants of interleukin-3 and chemical modifications thereof
CA2035868A1 (fr) *	1989-07-06	1991-01-07	Richard C. Svrluga	Molecules hybrides
AU632372B2 (en) *	1989-08-22	1992-12-24	Immunex Corporation	Fusion proteins comprising gm-csf and il-3
US5073627A (en) *	1989-08-22	1991-12-17	Immunex Corporation	Fusion proteins comprising GM-CSF and IL-3
IL96477A0 (en) *	1989-12-01	1991-08-16	Amgen Inc	Megakaryocyte production
AU651152B2 (en) *	1990-08-29	1994-07-14	Genetics Institute, Llc	Multidomain hematopoiesis stimulators

1991
- 1991-09-26 WO PCT/US1991/007053 patent/WO1992006116A1/fr not_active Application Discontinuation
- 1991-09-26 AU AU87359/91A patent/AU8735991A/en not_active Abandoned
- 1991-09-26 JP JP3517013A patent/JPH05502463A/ja active Pending
- 1991-09-26 EP EP19910918221 patent/EP0503050A4/en not_active Withdrawn
- 1991-09-26 CA CA002069746A patent/CA2069746A1/fr not_active Abandoned
- 1991-09-27 ZA ZA917766A patent/ZA917766B/xx unknown
- 1991-09-27 IE IE342691A patent/IE913426A1/en not_active Application Discontinuation
- 1991-09-27 PT PT99107A patent/PT99107A/pt not_active Application Discontinuation
1995
- 1995-02-06 AU AU11576/95A patent/AU1157695A/en not_active Abandoned

Also Published As

Publication number	Publication date
IE913426A1 (en)	1992-04-08
EP0503050A1 (fr)	1992-09-16
AU8735991A (en)	1992-04-28
PT99107A (pt)	1992-08-31
EP0503050A4 (en)	1994-07-06
WO1992006116A1 (fr)	1992-04-16
JPH05502463A (ja)	1993-04-28
CA2069746A1 (fr)	1992-03-29
AU1157695A (en)	1995-04-13

Publication	Publication Date	Title
ZA917766B (en)	1993-03-29	Hybrid growth factors.
DE69107059D1 (en)	1995-03-09	Sigma-delta-modulator.
AR244753A1 (es)	1993-11-30	Azocolorantes.
EP0456063A3 (en)	1992-07-08	1-h-3-aryl-pyrrolidin-2,4-dion-derivatives
GB2251034B (en)	1995-05-17	Shrouded aerofoils
EP0679163A4 (fr)	1997-07-16	Facteur-3 de croissance et de differenciation.
EP0565582A4 (fr)	1995-01-11	Nouveaux medicaments anti-inflammatoires suppresseurs de cytokine.
DE69104185D1 (en)	1994-10-27	Luftreservoir.
DE69112211D1 (en)	1995-09-21	Luftreinigungsvorrichtung.
DE69111595D1 (en)	1995-08-31	Squarylium- und crokonyliumfarbstoffe.
ZA928647B (en)	1993-06-21	Novel hybrid transforming growth factors.
EP0649734A3 (fr)	1996-02-07	Emballage.
DE69106281D1 (en)	1995-02-09	Phenanthrenderivat.
DE69102074D1 (en)	1994-06-23	Thermographische elemente.
DE69102644D1 (en)	1994-07-28	Demodulationsreferenzsignalquelle.
DE69110012D1 (en)	1995-06-29	Linienerkennungsverfahren.
DE69114491D1 (en)	1995-12-14	Olefincopolymere.
AR245079A1 (es)	1993-12-30	Procedimiento para preparar acido peroxomonosulfurico (acido de caro)
DE59102290D1 (en)	1994-08-25	Thermo-fixierstation mit bandtransport.
ZA931481B (en)	1993-09-23	Implants.
EP0481950A3 (en)	1992-09-02	1,4-dideoxy-4-fluoronojirimycin
EP0586848A3 (fr)	1995-01-25	Implant.
DE59100097D1 (en)	1993-06-03	Plungerzylinder.
IL96902A0 (en)	1992-03-29	T cell growth factor
ZA919371B (en)	1993-05-27	Containers.