ZA899114B - Amino acid derivatives - Google Patents

Amino acid derivatives

Info

Publication number: ZA899114B
Authority: ZA; South Africa
Prior art keywords: amino acid; acid derivatives; derivatives; amino; acid
Prior art date: 1988-11-30

Application number

ZA899114A

Other languages

English (en)

Inventor

Joachim Gante

Gante Joachim

Peter Raddatz

Raddatz Peter

Johannes Sombroek

Sombroek Johannes

Claus J Schmitges

J Schmitges Claus

Klaus Otto Minck

Otto Minck Klaus

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-11-30

Filing date

1989-11-29

Publication date

1990-08-29

1989-11-29 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

1990-08-29 Publication of ZA899114B publication Critical patent/ZA899114B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/80—Antihypertensive peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Crystallography & Structural Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA899114A 1988-11-30 1989-11-29 Amino acid derivatives ZA899114B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3840289A DE3840289A1 (de)	1988-11-30	1988-11-30	Aminosaeurederivate

Publications (1)

Publication Number	Publication Date
ZA899114B true ZA899114B (en)	1990-08-29

Family

ID=6368134

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA899114A ZA899114B (en)	1988-11-30	1989-11-29	Amino acid derivatives

Country Status (8)

Country	Link
US (1)	US5215967A (xx)
EP (1)	EP0371390A3 (xx)
JP (1)	JPH02193955A (xx)
AU (1)	AU622734B2 (xx)
CA (1)	CA2004001A1 (xx)
DE (1)	DE3840289A1 (xx)
HU (1)	HU205769B (xx)
ZA (1)	ZA899114B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW209870B (xx) *	1990-01-18	1993-07-21	Pfizer
EP0483403A1 (en) *	1990-10-31	1992-05-06	Hoechst Aktiengesellschaft	Derivatives of amino acids as inhibitors of renin, methods for their preparation, medicaments containing them and their use
US7141609B2 (en)	1992-08-25	2006-11-28	G.D. Searle & Co.	α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
ATE172717T1 (de)	1992-08-25	1998-11-15	Searle & Co	Hydroxyethylaminosulfonamide verwendbar als inhibitoren retroviraler proteasen
DE4425143A1 (de) *	1994-07-15	1996-01-18	Basf Ag	Substituierte Pyrimidinverbindungen und deren Verwendung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1258748A (en) *	1981-10-08	1989-08-22	Daniel F. Veber	Renin inhibitory peptides
CA1245217A (en) *	1981-12-10	1988-11-22	Joshua S. Boger	Renin inhibitory peptides having phe su13 xx deletion
AU573735B2 (en) *	1983-02-07	1988-06-23	Aktiebolaget Hassle	Peptide analogue enzyme inhibitors
EP0190891A3 (en) *	1985-01-31	1988-04-20	Kissei Pharmaceutical Co. Ltd.	Novel amino acid derivatives
ATE116994T1 (de) *	1986-06-10	1995-01-15	Merck Patent Gmbh	Reninhemmende aminosäurederivate.
DE3619508A1 (de) *	1986-06-10	1987-12-17	Merck Patent Gmbh	Aminosaeurederivate
US5032577A (en) *	1986-12-31	1991-07-16	Abbott Laboratories	Peptidylaminodiols
US4758584A (en) *	1987-02-05	1988-07-19	Ciba-Geigy Corporation	Antihypertensive 5-amino-4-hydroxyvaleryl derivatives substituted by sulphur-containing groups

1988
- 1988-11-30 DE DE3840289A patent/DE3840289A1/de not_active Withdrawn
1989
- 1989-11-23 EP EP19890121592 patent/EP0371390A3/de not_active Withdrawn
- 1989-11-28 AU AU45639/89A patent/AU622734B2/en not_active Ceased
- 1989-11-28 CA CA002004001A patent/CA2004001A1/en not_active Abandoned
- 1989-11-29 ZA ZA899114A patent/ZA899114B/xx unknown
- 1989-11-30 JP JP1309437A patent/JPH02193955A/ja active Pending
- 1989-11-30 HU HU896326A patent/HU205769B/hu unknown
- 1989-11-30 US US07/443,530 patent/US5215967A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE3840289A1 (de)	1990-05-31
HU896326D0 (en)	1990-02-28
AU4563989A (en)	1990-06-07
US5215967A (en)	1993-06-01
CA2004001A1 (en)	1990-05-31
EP0371390A2 (de)	1990-06-06
EP0371390A3 (de)	1991-01-30
HU205769B (en)	1992-06-29
AU622734B2 (en)	1992-04-16
HUT53374A (en)	1990-10-28
JPH02193955A (ja)	1990-07-31

Publication	Publication Date	Title
ZA902185B (en)	1990-12-28	Amino acid derivatives
AU3079789A (en)	1989-09-07	Amino acid derivatives
EP0416373A3 (en)	1992-05-27	Amino acid derivatives
ZA882347B (en)	1988-09-23	Amino acid derivatives
ZA887322B (en)	1989-06-28	Amino acid derivatives
ZA902444B (en)	1990-12-28	Amino acid derivatives
ZA893199B (en)	1990-01-31	Amino acid derivatives
ZA892720B (en)	1989-12-27	Amino acid derivatives
ZA887373B (en)	1989-06-28	Amino acid derivatives
ZA883782B (en)	1989-01-25	Amino acid derivatives
ZA899114B (en)	1990-08-29	Amino acid derivatives
ZA892059B (en)	1989-11-29	Amino acid derivatives
ZA902395B (en)	1990-12-28	Amino acid derivatives
ZA891265B (en)	1989-11-29	Amino acid derivatives
GB8707515D0 (en)	1987-05-07	Amino acid derivatives
ZA907585B (en)	1991-07-31	Amino acid derivatives
HRP930443A2 (en)	1996-12-31	Amino acid derivatives
ZA89906B (en)	1989-10-25	Amino acid derivatives
ZA894285B (en)	1990-02-28	Amino acid derivatives
ZA891659B (en)	1989-11-29	Amino acid derivatives
ZA891464B (en)	1989-12-27	Amino acid derivatives
IE882767L (en)	1989-03-18	Amino acid derivatives
IE880986L (en)	1988-10-03	Amino acid derivatives
IE891189L (en)	1989-10-14	Amino acid derivatives
IE890695L (en)	1989-09-04	Amino acid derivatives