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ZA887047B - Pharmaceutical products containing a 7-diphenylmethylenebicycloheptane or 7-diphenylmethylenebicycloheptene derivative,the use of these compounds as medicaments,and new 7-diphenylmethylenebicycloheptanes and 7-diphenylmethylenebicycloheptenes and processes for the preparation thereof - Google Patents

Pharmaceutical products containing a 7-diphenylmethylenebicycloheptane or 7-diphenylmethylenebicycloheptene derivative,the use of these compounds as medicaments,and new 7-diphenylmethylenebicycloheptanes and 7-diphenylmethylenebicycloheptenes and processes for the preparation thereof

Info

Publication number
ZA887047B
ZA887047B ZA887047A ZA887047A ZA887047B ZA 887047 B ZA887047 B ZA 887047B ZA 887047 A ZA887047 A ZA 887047A ZA 887047 A ZA887047 A ZA 887047A ZA 887047 B ZA887047 B ZA 887047B
Authority
ZA
South Africa
Prior art keywords
diphenylmethylenebicycloheptenes
diphenylmethylenebicycloheptene
diphenylmethylenebicycloheptanes
diphenylmethylenebicycloheptane
medicaments
Prior art date
Application number
ZA887047A
Inventor
Herbert Siegel
Siegel Herbert
Ernold Granzer
Granzer Ernold
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA887047B publication Critical patent/ZA887047B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Indole Compounds (AREA)
ZA887047A 1987-09-23 1988-09-21 Pharmaceutical products containing a 7-diphenylmethylenebicycloheptane or 7-diphenylmethylenebicycloheptene derivative,the use of these compounds as medicaments,and new 7-diphenylmethylenebicycloheptanes and 7-diphenylmethylenebicycloheptenes and processes for the preparation thereof ZA887047B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873731913 DE3731913A1 (en) 1987-09-23 1987-09-23 A pharmaceutical composition comprising A 7-DIPHENYLMETHYLENBICYCLOHEPTAN- OR 7 DIPHENYLMETHYLENBICYCLOHEPTEN DERIVATIVE, USE THESE COMPOUNDS AS DRUGS AND NEW 7-DIPHENYLMETHYLENBICYCLOHEPTANE AND 7-DIPHENYLMETHYLENBICLOHEPTENE AND METHOD FOR PRODUCING

Publications (1)

Publication Number Publication Date
ZA887047B true ZA887047B (en) 1989-06-28

Family

ID=6336607

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA887047A ZA887047B (en) 1987-09-23 1988-09-21 Pharmaceutical products containing a 7-diphenylmethylenebicycloheptane or 7-diphenylmethylenebicycloheptene derivative,the use of these compounds as medicaments,and new 7-diphenylmethylenebicycloheptanes and 7-diphenylmethylenebicycloheptenes and processes for the preparation thereof

Country Status (13)

Country Link
US (1) US5141937A (en)
EP (1) EP0308839A3 (en)
JP (1) JPH01113351A (en)
KR (1) KR890005041A (en)
AU (1) AU612177B2 (en)
DE (1) DE3731913A1 (en)
DK (1) DK527388A (en)
FI (1) FI884343A (en)
HU (2) HU204431B (en)
IL (1) IL87818A0 (en)
NO (1) NO884207L (en)
PT (1) PT88572B (en)
ZA (1) ZA887047B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4348993A (en) * 1992-06-19 1994-01-24 James Black Foundation Limited Bicyclooctane and bicycloheptane derivatives
RU2345981C2 (en) 2003-07-28 2009-02-10 Смитклайн Бичем Корпорейшн CYCLOALKYLIDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS BASED ON THEM, THEIR USE AND METHOD OF SELECTIVE BONDING ER α - AND ER β -ESTROGEN RECEPTORS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4550186A (en) * 1983-07-11 1985-10-29 Duke University Binuclear copper (II) carboxylates formed from amine-carboxyboranes
DE3410498A1 (en) * 1984-03-22 1985-10-03 Hoechst Ag, 6230 Frankfurt N-BICYCLOHEPTYL AND N-BICYCLOHEPTENYL IMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS

Also Published As

Publication number Publication date
JPH01113351A (en) 1989-05-02
NO884207L (en) 1989-03-28
AU2273088A (en) 1989-03-23
DE3731913A1 (en) 1989-04-06
KR890005041A (en) 1989-05-11
HUT48199A (en) 1989-05-29
FI884343A0 (en) 1988-09-21
DK527388D0 (en) 1988-09-22
IL87818A0 (en) 1989-03-31
HU204431B (en) 1992-01-28
AU612177B2 (en) 1991-07-04
PT88572A (en) 1988-10-01
PT88572B (en) 1992-11-30
HU200991B (en) 1990-09-28
NO884207D0 (en) 1988-09-22
DK527388A (en) 1989-03-24
FI884343A (en) 1989-03-24
EP0308839A3 (en) 1989-09-20
HU902054D0 (en) 1990-07-28
US5141937A (en) 1992-08-25
EP0308839A2 (en) 1989-03-29

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