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ZA813385B - Dibenzoxazepine derivative,process for preparing the same,and pharmaceutical composition comprising the same - Google Patents

Dibenzoxazepine derivative,process for preparing the same,and pharmaceutical composition comprising the same

Info

Publication number
ZA813385B
ZA813385B ZA00813385A ZA813385A ZA813385B ZA 813385 B ZA813385 B ZA 813385B ZA 00813385 A ZA00813385 A ZA 00813385A ZA 813385 A ZA813385 A ZA 813385A ZA 813385 B ZA813385 B ZA 813385B
Authority
ZA
South Africa
Prior art keywords
same
preparing
pharmaceutical composition
lowering activity
activity
Prior art date
Application number
ZA00813385A
Other languages
English (en)
Inventor
Kazuo Sasahara
Sasahara Kazuo
Masamitsu Honda
Honda Masamitsu
Masuo Koizumi
Koizumi Masuo
Yasushi Murakami
Murakami Yasushi
Tomohiro Neichi
Neichi Tomohiro
Hiroshi Nakakimura
Nakakimura Hiroshi
Yukifumi Noda
Noda Yukifumi
Hiroshi Matsushita
Matsushita Hiroshi
Shun Ichi Hata
Ichi Hata Shun
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of ZA813385B publication Critical patent/ZA813385B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D267/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02Seven-membered rings
    • C07D267/08Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/16Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D267/20[b, f]-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA00813385A 1980-05-28 1981-05-20 Dibenzoxazepine derivative,process for preparing the same,and pharmaceutical composition comprising the same ZA813385B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7017680A JPS56166180A (en) 1980-05-28 1980-05-28 Dibenzoxazepine derivative and its preparation

Publications (1)

Publication Number Publication Date
ZA813385B true ZA813385B (en) 1982-06-30

Family

ID=13423954

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00813385A ZA813385B (en) 1980-05-28 1981-05-20 Dibenzoxazepine derivative,process for preparing the same,and pharmaceutical composition comprising the same

Country Status (11)

Country Link
US (1) US4435391A (xx)
EP (1) EP0040860B1 (xx)
JP (1) JPS56166180A (xx)
KR (1) KR850000212B1 (xx)
AT (1) ATE6645T1 (xx)
CA (1) CA1162189A (xx)
DE (1) DE3162614D1 (xx)
HU (1) HU183456B (xx)
IL (1) IL62894A (xx)
MX (1) MX157054A (xx)
ZA (1) ZA813385B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0240721A3 (en) * 1986-03-12 1991-01-02 Chugai Seiyaku Kabushiki Kaisha Therapeutic agent for the treatment of peripheral circulatory disorders
CA2200598C (en) * 1994-09-28 1999-12-07 Shuji Jinno Novel anti-oxidative, tricyclic, condensed heterocyclic compound
WO1996033983A1 (fr) * 1995-04-25 1996-10-31 Daiichi Radioisotope Laboratories, Ltd. Derives n-oxyde de dibenzoxazepine et medicament les contenant en tant que principe actif
JP4582366B2 (ja) * 1998-11-30 2010-11-17 東レ・ファインケミカル株式会社 ピロリジン誘導体の製造法
US7550499B2 (en) * 2004-05-12 2009-06-23 Bristol-Myers Squibb Company Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
WO2006078621A2 (en) * 2005-01-19 2006-07-27 Bristol-Myers Squibb Company 2-phenoxy-n- (1, 3 , 4-thiadizol-2-yl) pyridin-3-amine derivatives and related compounds as p2y1 receptor inhibitors for the treatment of thromboembolic disorders
WO2007002634A1 (en) * 2005-06-27 2007-01-04 Bristol-Myers Squibb Company Carbocycle and heterocycle antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
ATE502924T1 (de) * 2005-06-27 2011-04-15 Bristol Myers Squibb Co Lineare harnstoffmimetika-antagonisten des p2y1- rezeptors zur behandlung von thromboseleiden
ES2352796T3 (es) * 2005-06-27 2011-02-23 Bristol-Myers Squibb Company Antagonistas cíclicos unidos a c del receptor p2y1 útiles en el tratamiento de afecciones trombóticas.
KR20080027890A (ko) * 2005-06-27 2008-03-28 브리스톨-마이어스 스큅 컴퍼니 혈전성 증상의 치료에 유용한 p2y1 수용체의 n-연결헤테로시클릭 길항제
US20080090805A1 (en) * 2005-10-17 2008-04-17 Acadia Pharmaceuticals Inc. Cb-1 modulating compounds and their use
CA2625423A1 (en) * 2005-10-17 2007-04-26 Acadia Pharmaceuticals Inc. Cb-1 modulating compounds and their use
US7960569B2 (en) * 2006-10-17 2011-06-14 Bristol-Myers Squibb Company Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
ES2535730T3 (es) 2007-12-05 2015-05-14 Janssen Pharmaceutica, N.V. Agonistas TRPA1 de dibenzoazepinas y dibenzooxazepinas
WO2019173761A1 (en) * 2018-03-09 2019-09-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services C-abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH473141A (de) 1965-12-30 1969-05-31 Wander Ag Dr A Verfahren zur Herstellung 11-aminoalkylierter Dibenz(b,f)-1,4-oxazepine und Dibenzo(b,f)-1,4-thiazepine
US3646009A (en) 1967-03-15 1972-02-29 Boehringer & Soehne Gmbh Anti-diabetically active sulfonyl-semicarbazides
US3458516A (en) 1968-02-16 1969-07-29 American Cyanamid Co 11-(piperazinyl)dibenz(b,f)(1,4)oxazepines and analogous thiazepines
US3676460A (en) 1969-03-28 1972-07-11 Sumitomo Chemical Co Benzoxazepine derivatives
JPS5576869A (en) * 1978-12-06 1980-06-10 Chugai Pharmaceut Co Ltd Dibenzoxazepine derivative and its preparation

Also Published As

Publication number Publication date
KR830006249A (ko) 1983-09-20
EP0040860A1 (en) 1981-12-02
DE3162614D1 (en) 1984-04-19
ATE6645T1 (de) 1984-03-15
IL62894A0 (en) 1981-07-31
MX157054A (es) 1988-10-24
IL62894A (en) 1984-10-31
EP0040860B1 (en) 1984-03-14
KR850000212B1 (ko) 1985-03-06
JPS56166180A (en) 1981-12-21
JPH0223550B2 (xx) 1990-05-24
HU183456B (en) 1984-05-28
US4435391A (en) 1984-03-06
CA1162189A (en) 1984-02-14

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