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ZA739543B - Free-flowing, directly tablettable, pharmaceutically active substances - Google Patents

Free-flowing, directly tablettable, pharmaceutically active substances

Info

Publication number
ZA739543B
ZA739543B ZA00739543A ZA739543A ZA739543B ZA 739543 B ZA739543 B ZA 739543B ZA 00739543 A ZA00739543 A ZA 00739543A ZA 739543 A ZA739543 A ZA 739543A ZA 739543 B ZA739543 B ZA 739543B
Authority
ZA
South Africa
Prior art keywords
flowing
free
active substances
pharmaceutically active
directly tablettable
Prior art date
Application number
ZA00739543A
Inventor
P Seth
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA739543B publication Critical patent/ZA739543B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
ZA00739543A 1973-02-16 1973-12-18 Free-flowing, directly tablettable, pharmaceutically active substances ZA739543B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH233173 1973-02-16

Publications (1)

Publication Number Publication Date
ZA739543B true ZA739543B (en) 1975-03-26

Family

ID=4231310

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00739543A ZA739543B (en) 1973-02-16 1973-12-18 Free-flowing, directly tablettable, pharmaceutically active substances

Country Status (10)

Country Link
US (1) US3907983A (en)
JP (1) JPS49110820A (en)
AU (1) AU6401073A (en)
BE (1) BE811062A (en)
DE (1) DE2404609B2 (en)
FR (1) FR2218085B1 (en)
GB (1) GB1465781A (en)
IL (1) IL43853A0 (en)
NL (1) NL7400298A (en)
ZA (1) ZA739543B (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5438167B2 (en) * 1974-04-27 1979-11-19
US4291016A (en) * 1976-07-27 1981-09-22 Sandoz Ltd. Enteric coated mixture of 4-(2-hydroxy-3-isopropylamino-propoxy) indole and sodium lauryl sulphate
US4122157A (en) 1977-03-04 1978-10-24 Richardson-Merrell Inc. Nitrofurantoin sustained release tablet
JPS5668609A (en) 1979-11-07 1981-06-09 Nippon Kayaku Co Ltd Phthalazinol preparation
US4252786A (en) * 1979-11-16 1981-02-24 E. R. Squibb & Sons, Inc. Controlled release tablet
US4302440B1 (en) * 1980-07-31 1986-08-05 Easily-swallowed, powder-free and gastric-disintegrable aspirin tablet thinly-coated with hydroxypropyl methylcellulose and aqueous spray-coating preparation thereof
US4508702A (en) * 1982-06-14 1985-04-02 Key Pharmaceuticals, Inc. Sustained release aspirin
US4634587A (en) * 1982-07-09 1987-01-06 Key Pharmaceuticals, Inc. Sustained release quinidine dosage form
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
US4555399A (en) * 1983-11-18 1985-11-26 Key Pharmaceuticals, Inc. Aspirin tablet
SE457505B (en) * 1984-01-10 1989-01-09 Lejus Medical Ab LAMINATED ORAL PHARMACEUTICAL COMPOSITION AND PROCEDURES FOR ITS PREPARATION
GB2155330B (en) * 1984-03-08 1988-01-27 Squibb & Sons Inc Solvent granulation technique for forming solid formulations of nystatin
JPH0753663B2 (en) * 1984-10-09 1995-06-07 武田薬品工業株式会社 Thiamine salt granules, their production and tablets
WO1986003675A1 (en) * 1984-12-14 1986-07-03 Gerhard Gergely Particles from a hydrophobic or poorly soluble substance and process for rendering them hydrophilic
US4818539A (en) * 1985-02-05 1989-04-04 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4843098A (en) * 1985-02-05 1989-06-27 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4790991A (en) * 1985-02-05 1988-12-13 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4851392A (en) * 1985-02-05 1989-07-25 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4747881A (en) * 1985-02-05 1988-05-31 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
LU85943A1 (en) * 1985-06-12 1987-01-13 Galephar PHARMACEUTICAL TABLETS FOR THE EASY ADMINISTRATION OF PELLETS, THEIR PREPARATION AND THEIR USE
US4710519A (en) * 1985-09-30 1987-12-01 Basf Corporation Process for preparing spray dried acetaminophen powder and the powder prepared thereby
AU587863B2 (en) * 1985-10-07 1989-08-31 Basf Aktiengesellschaft Vitamin-containing granules and production thereof
US4837033A (en) * 1987-12-22 1989-06-06 Shin-Etsu Chemical Co., Ltd. Method for the preparation of a coated solid medicament
US5662922A (en) * 1992-01-20 1997-09-02 Christensen; Borge Holm Iron-containing composition for the prevention of anaemia and a method for producing the composition
DK6492D0 (en) * 1992-01-20 1992-01-20 Boerge Holm Christensen GRANT FEED
JP2669446B2 (en) * 1992-03-23 1997-10-27 信越化学工業株式会社 Raw material powder for pharmaceutical coating liquid
AU4198793A (en) 1992-07-24 1994-01-27 Takeda Chemical Industries Ltd. Microparticle preparation and production thereof
US5560927A (en) * 1995-07-28 1996-10-01 Isp Investments Inc. Co-processing method for making a free-flowing compressible powder and tablet therefrom
JP3555640B2 (en) * 1996-05-10 2004-08-18 ライオン株式会社 Multicapsulated microcapsules containing natural carotenoids, tablets, food and pharmaceutical compounds
US20070202182A1 (en) * 2006-02-26 2007-08-30 Kane Kevin M Preparing solid formulation of nanoparticles of pharmaceutical ingredient, including at least micron-sized particles
US20100034959A1 (en) * 2008-08-07 2010-02-11 Vector Corporation High solids, high molecular weight polymer coating

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1492034A1 (en) * 1965-05-18 1969-02-20 Merck Ag E Process for the production of solid, long-lasting preparations of sensitive active substances that are poorly soluble in water, preferably pharmaceuticals
AU1039170A (en) * 1969-02-24 1971-07-22 Abbott Laboratories Tableting medium
NL7112083A (en) * 1970-09-16 1972-03-20

Also Published As

Publication number Publication date
IL43853A0 (en) 1974-03-14
AU6401073A (en) 1975-07-03
BE811062A (en) 1974-08-16
US3907983A (en) 1975-09-23
NL7400298A (en) 1974-08-20
DE2404609B2 (en) 1978-05-18
JPS49110820A (en) 1974-10-22
FR2218085A1 (en) 1974-09-13
GB1465781A (en) 1977-03-02
FR2218085B1 (en) 1977-11-10
DE2404609A1 (en) 1974-09-05

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