YU39849B - Process for preparing 2-bromo-ergolene and 2-bromo-ergoline compounds - Google Patents

Process for preparing 2-bromo-ergolene and 2-bromo-ergoline compounds

Info

Publication number: YU39849B
Authority: YU; Yugoslavia
Prior art keywords: bromo; ergolene; preparing; ergoline compounds; ergoline
Prior art date: 1978-09-26

Application number

YU2268/78A

Other versions

YU226878A (en

Inventor

M Jurgec

R Rucman

B Stanovnik

M Tisler

Original Assignee

Lek Tovarna Farmacevtskih

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-09-26

Filing date

1978-09-26

Publication date

1985-04-30

1978-09-26 Application filed by Lek Tovarna Farmacevtskih filed Critical Lek Tovarna Farmacevtskih

1978-09-26 Priority to YU2268/78A priority Critical patent/YU39849B/en

1979-09-19 Priority to IT7950300A priority patent/IT1206988B/en

1979-09-20 Priority to CH8492/79A priority patent/CH649769A5/en

1979-09-21 Priority to DE19792938313 priority patent/DE2938313A1/en

1979-09-24 Priority to GR60103A priority patent/GR73015B/el

1979-09-24 Priority to NO793058A priority patent/NO153852C/en

1979-09-24 Priority to CY1240A priority patent/CY1240A/en

1979-09-24 Priority to DD79215747A priority patent/DD146048A5/en

1979-09-24 Priority to MX798393U priority patent/MX5864E/en

1979-09-24 Priority to IS2512A priority patent/IS2512A7/en

1979-09-24 Priority to PT70216A priority patent/PT70216A/en

1979-09-24 Priority to AR278180A priority patent/AR223496A1/en

1979-09-24 Priority to FI792957A priority patent/FI66185C/en

1979-09-24 Priority to BE1/9540A priority patent/BE878953A/en

1979-09-24 Priority to NZ191643A priority patent/NZ191643A/en

1979-09-24 Priority to HU79SA3200A priority patent/HU182576B/en

1979-09-24 Priority to LU81714A priority patent/LU81714A1/en

1979-09-24 Priority to AT0624379A priority patent/AT376439B/en

1979-09-24 Priority to GB7932989A priority patent/GB2031890B/en

1979-09-25 Priority to EG566/79A priority patent/EG14277A/en

1979-09-25 Priority to NL7907122A priority patent/NL7907122A/en

1979-09-25 Priority to JP12373279A priority patent/JPS5545699A/en

1979-09-25 Priority to FR7923816A priority patent/FR2437411A1/en

1979-09-25 Priority to RO7998760A priority patent/RO78936A/en

1979-09-25 Priority to BG044956A priority patent/BG32716A3/en

1979-09-25 Priority to PL1979218497A priority patent/PL120388B1/en

1979-09-25 Priority to IL58318A priority patent/IL58318A/en

1979-09-25 Priority to SE7907942A priority patent/SE433497B/en

1979-09-25 Priority to DK401979A priority patent/DK149956C/en

1979-09-25 Priority to CS796471A priority patent/CS215027B2/en

1979-09-25 Priority to MA18795A priority patent/MA18595A1/en

1979-09-25 Priority to UA2818045A priority patent/UA7078A1/en

1979-09-25 Priority to ES484445A priority patent/ES484445A1/en

1979-09-25 Priority to SU792818045A priority patent/SU1178324A3/en

1979-09-25 Priority to PH23062A priority patent/PH14986A/en

1979-09-25 Priority to AU51172/79A priority patent/AU529462B2/en

1979-09-26 Priority to BR7906175A priority patent/BR7906175A/en

1979-09-26 Priority to CA336,448A priority patent/CA1128038A/en

1979-09-26 Priority to IE1832/79A priority patent/IE49076B1/en

1979-09-26 Priority to ZA00795110A priority patent/ZA795110B/en

1980-09-23 Priority to IN1077/CAL/80A priority patent/IN154914B/en

1983-01-21 Publication of YU226878A publication Critical patent/YU226878A/en

1984-03-05 Priority to SG204/84A priority patent/SG20484G/en

1984-04-12 Priority to KE3392A priority patent/KE3392A/en

1984-06-14 Priority to HK491/84A priority patent/HK49184A/en

1985-04-30 Publication of YU39849B publication Critical patent/YU39849B/en

1985-12-30 Priority to MY131/85A priority patent/MY8500131A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)

YU2268/78A 1978-09-26 1978-09-26 Process for preparing 2-bromo-ergolene and 2-bromo-ergoline compounds YU39849B (en)

Priority Applications (45)

Application Number	Priority Date	Filing Date	Title
YU2268/78A YU39849B (en)	1978-09-26	1978-09-26	Process for preparing 2-bromo-ergolene and 2-bromo-ergoline compounds
IT7950300A IT1206988B (en)	1978-09-26	1979-09-19	OF ALCALOIDS OF THE SIGNAL CONCERNED BROMURATION PROCEDURE
CH8492/79A CH649769A5 (en)	1978-09-26	1979-09-20	METHOD FOR SELECTIVELY BROWNING ERGOTAL CALOIDS AND RELATED COMPOUNDS.
DE19792938313 DE2938313A1 (en)	1978-09-26	1979-09-21	IMPROVEMENTS IN OR REGARDING BROWNING PROCESSES
GR60103A GR73015B (en)	1978-09-26	1979-09-24
NO793058A NO153852C (en)	1978-09-26	1979-09-24	PROCEDURE FOR THE PREPARATION OF SELECTIVE BROMATED ORGANIC COMPOUNDS.
CY1240A CY1240A (en)	1978-09-26	1979-09-24	Process for the preparation of brominated ergot alkaloids
DD79215747A DD146048A5 (en)	1978-09-26	1979-09-24	IMPROVEMENTS IN OR WITH REGARD TO COMBUSTION PROCESSES
MX798393U MX5864E (en)	1978-09-26	1979-09-24	IMPROVED PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 2-BROMO-ERGOLENE AND 2-BROMO-ERGOLINE
IS2512A IS2512A7 (en)	1978-09-26	1979-09-24	Improvement of the method of placing bromine into special compounds
PT70216A PT70216A (en)	1978-09-26	1979-09-24	Process for preparing brominated compounds
AR278180A AR223496A1 (en)	1978-09-26	1979-09-24	PROCEDURE FOR OBTAINING DERIVATIVES OF 2-BROMOLISERGICO ACID OR 2-BRMOOL-9,10-DIHIDROLISERGICO
FI792957A FI66185C (en)	1978-09-26	1979-09-24	NYTT FOERFARANDE FOER BROMERING AV FOERENINGAR
BE1/9540A BE878953A (en)	1978-09-26	1979-09-24	PROCESS FOR BROMINATING ALKALOIDS OF RYE ERGOT
NZ191643A NZ191643A (en)	1978-09-26	1979-09-24	Bromination of ergot alkaloids with a bromine complex of 3-bromo-6-chloro-2-methylimidazo (1,2-b) pyridazine
HU79SA3200A HU182576B (en)	1978-09-26	1979-09-24	Process for selective brominating ergotalkaloides and lysergic acid derivatives at the 2 position
LU81714A LU81714A1 (en)	1978-09-26	1979-09-24	PROCESS FOR BROMINATING ALKALOIDS OF RYE ERGOT
AT0624379A AT376439B (en)	1978-09-26	1979-09-24	METHOD FOR PRODUCING ERGOTAL CALALID
GB7932989A GB2031890B (en)	1978-09-26	1979-09-24	Process for the preparation of brominated ergot alkaloids
RO7998760A RO78936A (en)	1978-09-26	1979-09-25	PROCESS FOR THE PREPATATION OF ALPHAERGOCRYPTIN DERIVATIVES
ES484445A ES484445A1 (en)	1978-09-26	1979-09-25	Process for the preparation of brominated ergot alkaloids
JP12373279A JPS5545699A (en)	1978-09-26	1979-09-25	Manufacture of bromide of ergot alkaloids
FR7923816A FR2437411A1 (en)	1978-09-26	1979-09-25	PROCESS FOR BROMINATING ALKALOIDS IN RYE ERGOT AND COMPOUNDS OBTAINED
EG566/79A EG14277A (en)	1978-09-26	1979-09-25	Improvements in or relating to bromination process
BG044956A BG32716A3 (en)	1978-09-26	1979-09-25	Method for obtaining of bromine alcaloids
PL1979218497A PL120388B1 (en)	1978-09-26	1979-09-25	Method of manufacture of ergot alkaloids bromine derivatives
IL58318A IL58318A (en)	1978-09-26	1979-09-25	Process for the bromination of ergot alkaloids
SE7907942A SE433497B (en)	1978-09-26	1979-09-25	SET TO BRROME ERGOTAL CALOIDS
DK401979A DK149956C (en)	1978-09-26	1979-09-25	PROCEDURE FOR THE PREPARATION OF BROOM-CONTAINED ERGOTAL KALOIDS
CS796471A CS215027B2 (en)	1978-09-26	1979-09-25	Method of preparation of 2-bromergot alcaloids
MA18795A MA18595A1 (en)	1978-09-26	1979-09-25	PROCESS FOR THE FORMATION OF ALCOHOLIDES OF RYE ERGOT
UA2818045A UA7078A1 (en)	1978-09-26	1979-09-25	METHOD OF OBTAINING 2-BROMO-DERIVATIVE ARGOALKALOIDS
NL7907122A NL7907122A (en)	1978-09-26	1979-09-25	Bromination method.
SU792818045A SU1178324A3 (en)	1978-09-26	1979-09-25	Method of producing 2-bromine derivatives of ergoalkaloids
PH23062A PH14986A (en)	1978-09-26	1979-09-25	Improvements in or relating to bromination processes
AU51172/79A AU529462B2 (en)	1978-09-26	1979-09-25	Bromination of ergot alkaloids
BR7906175A BR7906175A (en)	1978-09-26	1979-09-26	PROCESS FOR THE PRODUCTION OF A COMPOUND
CA336,448A CA1128038A (en)	1978-09-26	1979-09-26	Bromination process of ergot alkaloids
IE1832/79A IE49076B1 (en)	1978-09-26	1979-09-26	Process for the preparation of brominated ergot alkaloids
ZA00795110A ZA795110B (en)	1978-09-26	1979-09-26	Bromination processes
IN1077/CAL/80A IN154914B (en)	1978-09-26	1980-09-23
SG204/84A SG20484G (en)	1978-09-26	1984-03-05	Process for the preparation of brominated ergot alkaloids
KE3392A KE3392A (en)	1978-09-26	1984-04-12	Process for the preparation of brominated ergot alkaloids
HK491/84A HK49184A (en)	1978-09-26	1984-06-14	Process for the preparation of brominated ergot alkaloids
MY131/85A MY8500131A (en)	1978-09-26	1985-12-30	Process for the preparation of brominated ergot alkaloids

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
YU2268/78A YU39849B (en)	1978-09-26	1978-09-26	Process for preparing 2-bromo-ergolene and 2-bromo-ergoline compounds

Publications (2)

Publication Number	Publication Date
YU226878A YU226878A (en)	1983-01-21
YU39849B true YU39849B (en)	1985-04-30

Family

ID=25557457

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU2268/78A YU39849B (en)	1978-09-26	1978-09-26	Process for preparing 2-bromo-ergolene and 2-bromo-ergoline compounds

Country Status (45)

Country	Link
JP (1)	JPS5545699A (en)
AR (1)	AR223496A1 (en)
AT (1)	AT376439B (en)
AU (1)	AU529462B2 (en)
BE (1)	BE878953A (en)
BG (1)	BG32716A3 (en)
BR (1)	BR7906175A (en)
CA (1)	CA1128038A (en)
CH (1)	CH649769A5 (en)
CS (1)	CS215027B2 (en)
CY (1)	CY1240A (en)
DD (1)	DD146048A5 (en)
DE (1)	DE2938313A1 (en)
DK (1)	DK149956C (en)
EG (1)	EG14277A (en)
ES (1)	ES484445A1 (en)
FI (1)	FI66185C (en)
FR (1)	FR2437411A1 (en)
GB (1)	GB2031890B (en)
GR (1)	GR73015B (en)
HK (1)	HK49184A (en)
HU (1)	HU182576B (en)
IE (1)	IE49076B1 (en)
IL (1)	IL58318A (en)
IN (1)	IN154914B (en)
IS (1)	IS2512A7 (en)
IT (1)	IT1206988B (en)
KE (1)	KE3392A (en)
LU (1)	LU81714A1 (en)
MA (1)	MA18595A1 (en)
MX (1)	MX5864E (en)
MY (1)	MY8500131A (en)
NL (1)	NL7907122A (en)
NO (1)	NO153852C (en)
NZ (1)	NZ191643A (en)
PH (1)	PH14986A (en)
PL (1)	PL120388B1 (en)
PT (1)	PT70216A (en)
RO (1)	RO78936A (en)
SE (1)	SE433497B (en)
SG (1)	SG20484G (en)
SU (1)	SU1178324A3 (en)
UA (1)	UA7078A1 (en)
YU (1)	YU39849B (en)
ZA (1)	ZA795110B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives
CN104016982A (en) *	2014-06-26	2014-09-03	华东理工大学	Method for preparing fumigaclavine C by using macroporous resin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH507249A (en) *	1968-05-31	1971-05-15	Sandoz Ag	Process for the preparation of 2-bromo-a-ergocryptine
YU39786B (en) *	1976-12-23	1985-04-30	Lek Tovarna Farmacevtskih	Process for preparing 2-bromo-alfa-ergocriptine
YU216177A (en) *	1977-09-09	1984-02-29	Rudolf Rucman	Process for preparing 2-bromo ergosine

1978
- 1978-09-26 YU YU2268/78A patent/YU39849B/en unknown
1979
- 1979-09-19 IT IT7950300A patent/IT1206988B/en active
- 1979-09-20 CH CH8492/79A patent/CH649769A5/en not_active IP Right Cessation
- 1979-09-21 DE DE19792938313 patent/DE2938313A1/en active Granted
- 1979-09-24 GR GR60103A patent/GR73015B/el unknown
- 1979-09-24 NZ NZ191643A patent/NZ191643A/en unknown
- 1979-09-24 IS IS2512A patent/IS2512A7/en unknown
- 1979-09-24 BE BE1/9540A patent/BE878953A/en not_active IP Right Cessation
- 1979-09-24 GB GB7932989A patent/GB2031890B/en not_active Expired
- 1979-09-24 MX MX798393U patent/MX5864E/en unknown
- 1979-09-24 HU HU79SA3200A patent/HU182576B/en unknown
- 1979-09-24 LU LU81714A patent/LU81714A1/en unknown
- 1979-09-24 AR AR278180A patent/AR223496A1/en active
- 1979-09-24 NO NO793058A patent/NO153852C/en unknown
- 1979-09-24 FI FI792957A patent/FI66185C/en not_active IP Right Cessation
- 1979-09-24 AT AT0624379A patent/AT376439B/en not_active IP Right Cessation
- 1979-09-24 PT PT70216A patent/PT70216A/en unknown
- 1979-09-24 DD DD79215747A patent/DD146048A5/en not_active IP Right Cessation
- 1979-09-24 CY CY1240A patent/CY1240A/en unknown
- 1979-09-25 BG BG044956A patent/BG32716A3/en unknown
- 1979-09-25 EG EG566/79A patent/EG14277A/en active
- 1979-09-25 UA UA2818045A patent/UA7078A1/en unknown
- 1979-09-25 FR FR7923816A patent/FR2437411A1/en active Granted
- 1979-09-25 PH PH23062A patent/PH14986A/en unknown
- 1979-09-25 MA MA18795A patent/MA18595A1/en unknown
- 1979-09-25 SU SU792818045A patent/SU1178324A3/en active
- 1979-09-25 DK DK401979A patent/DK149956C/en not_active IP Right Cessation
- 1979-09-25 AU AU51172/79A patent/AU529462B2/en not_active Ceased
- 1979-09-25 ES ES484445A patent/ES484445A1/en not_active Expired
- 1979-09-25 RO RO7998760A patent/RO78936A/en unknown
- 1979-09-25 IL IL58318A patent/IL58318A/en unknown
- 1979-09-25 PL PL1979218497A patent/PL120388B1/en unknown
- 1979-09-25 NL NL7907122A patent/NL7907122A/en not_active Application Discontinuation
- 1979-09-25 JP JP12373279A patent/JPS5545699A/en active Granted
- 1979-09-25 CS CS796471A patent/CS215027B2/en unknown
- 1979-09-25 SE SE7907942A patent/SE433497B/en not_active IP Right Cessation
- 1979-09-26 BR BR7906175A patent/BR7906175A/en unknown
- 1979-09-26 IE IE1832/79A patent/IE49076B1/en not_active IP Right Cessation
- 1979-09-26 ZA ZA00795110A patent/ZA795110B/en unknown
- 1979-09-26 CA CA336,448A patent/CA1128038A/en not_active Expired
1980
- 1980-09-23 IN IN1077/CAL/80A patent/IN154914B/en unknown
1984
- 1984-03-05 SG SG204/84A patent/SG20484G/en unknown
- 1984-04-12 KE KE3392A patent/KE3392A/en unknown
- 1984-06-14 HK HK491/84A patent/HK49184A/en not_active IP Right Cessation
1985
- 1985-12-30 MY MY131/85A patent/MY8500131A/en unknown

Also Published As

Publication number	Publication date
CY1240A (en)	1984-06-29
JPS6239158B2 (en)	1987-08-21
RO78936A (en)	1982-07-06
DE2938313A1 (en)	1980-04-10
DK401979A (en)	1980-03-27
SU1178324A3 (en)	1985-09-07
HK49184A (en)	1984-06-22
IS1161B6 (en)	1984-05-10
FI792957A (en)	1980-03-27
IL58318A0 (en)	1979-12-30
ES484445A1 (en)	1980-09-01
PL218497A1 (en)	1980-07-14
CH649769A5 (en)	1985-06-14
LU81714A1 (en)	1980-04-21
EG14277A (en)	1990-06-30
GB2031890A (en)	1980-04-30
IN154914B (en)	1984-12-22
SG20484G (en)	1985-03-08
BE878953A (en)	1980-03-24
IT7950300A0 (en)	1979-09-19
GB2031890B (en)	1983-02-02
KE3392A (en)	1984-06-08
AU5117279A (en)	1980-04-03
ATA624379A (en)	1984-04-15
AR223496A1 (en)	1981-08-31
FR2437411B1 (en)	1983-03-18
AU529462B2 (en)	1983-06-09
PT70216A (en)	1979-10-01
UA7078A1 (en)	1995-06-30
IL58318A (en)	1982-07-30
FR2437411A1 (en)	1980-04-25
MY8500131A (en)	1985-12-31
IT1206988B (en)	1989-05-17
HU182576B (en)	1984-02-28
MX5864E (en)	1984-08-13
NO153852B (en)	1986-02-24
CS215027B2 (en)	1982-06-25
NO793058L (en)	1980-03-27
ZA795110B (en)	1981-05-27
GR73015B (en)	1984-01-25
FI66185B (en)	1984-05-31
CA1128038A (en)	1982-07-20
PH14986A (en)	1982-03-05
IE791832L (en)	1980-03-26
IE49076B1 (en)	1985-07-24
SE7907942L (en)	1980-03-27
DK149956B (en)	1986-11-03
NO153852C (en)	1986-06-04
MA18595A1 (en)	1980-04-01
FI66185C (en)	1984-09-10
DD146048A5 (en)	1981-01-21
NZ191643A (en)	1982-05-25
AT376439B (en)	1984-11-26
IS2512A7 (en)	1988-03-27
BG32716A3 (en)	1982-09-15
JPS5545699A (en)	1980-03-31
NL7907122A (en)	1980-03-28
SE433497B (en)	1984-05-28
DK149956C (en)	1987-05-18
DE2938313C2 (en)	1988-07-07
PL120388B1 (en)	1982-02-27
YU226878A (en)	1983-01-21
BR7906175A (en)	1980-05-27

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