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WO2024223385A1 - Fourniture de guidage respiratoire à un individu - Google Patents

Fourniture de guidage respiratoire à un individu Download PDF

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Publication number
WO2024223385A1
WO2024223385A1 PCT/EP2024/060462 EP2024060462W WO2024223385A1 WO 2024223385 A1 WO2024223385 A1 WO 2024223385A1 EP 2024060462 W EP2024060462 W EP 2024060462W WO 2024223385 A1 WO2024223385 A1 WO 2024223385A1
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WO
WIPO (PCT)
Prior art keywords
segment
breathing
length
individual
target
Prior art date
Application number
PCT/EP2024/060462
Other languages
English (en)
Inventor
Sheng Jin
Original Assignee
Koninklijke Philips N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips N.V. filed Critical Koninklijke Philips N.V.
Publication of WO2024223385A1 publication Critical patent/WO2024223385A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A63SPORTS; GAMES; AMUSEMENTS
    • A63BAPPARATUS FOR PHYSICAL TRAINING, GYMNASTICS, SWIMMING, CLIMBING, OR FENCING; BALL GAMES; TRAINING EQUIPMENT
    • A63B23/00Exercising apparatus specially adapted for particular parts of the body
    • A63B23/18Exercising apparatus specially adapted for particular parts of the body for improving respiratory function
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M21/02Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis for inducing sleep or relaxation, e.g. by direct nerve stimulation, hypnosis, analgesia
    • AHUMAN NECESSITIES
    • A63SPORTS; GAMES; AMUSEMENTS
    • A63BAPPARATUS FOR PHYSICAL TRAINING, GYMNASTICS, SWIMMING, CLIMBING, OR FENCING; BALL GAMES; TRAINING EQUIPMENT
    • A63B23/00Exercising apparatus specially adapted for particular parts of the body
    • A63B23/18Exercising apparatus specially adapted for particular parts of the body for improving respiratory function
    • A63B23/185Rhythm indicators
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/30ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
    • AHUMAN NECESSITIES
    • A47FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47GHOUSEHOLD OR TABLE EQUIPMENT
    • A47G9/00Bed-covers; Counterpanes; Travelling rugs; Sleeping rugs; Sleeping bags; Pillows
    • A47G9/10Pillows
    • A47G9/1045Pillows shaped as, combined with, or convertible into other articles, e.g. dolls, sound equipments, bags or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0022Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the tactile sense, e.g. vibrations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0027Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0044Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the sight sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0088Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus modulated by a simulated respiratory frequency
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/35Communication
    • A61M2205/3576Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3592Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/40Respiratory characteristics
    • A61M2230/42Rate

Definitions

  • the present invention relates to the field of breathing guidance.
  • a slow and regular breathing action is considered beneficial for relaxation. More specifically, research has shown that paced or guided breathing leads to a physiological effect or outcome in humans/mammals, including reduced blood pressure and improved oxygenation of blood.
  • One particularly useful use-case scenario for providing paced/guided breathing is to encourage or aid in falling asleep. More particularly, the physiological changes in an individual that result from paced/guided breathing are similar to those that occur whilst the individual is falling asleep.
  • One example device is a guided breathing hugging pillow.
  • the surface of the pillow can fluctuate up and down (e.g., by inflating/deflating an airbag) to simulate a breathing pattern for the individual.
  • the individual can feel and follow this pattern to control their breathing by tactile sensing while touching the pillow.
  • US patent application US 2019/030278 Al discloses a method that provides respiration entrainment cues to a user to encourage relaxation or a sleep state.
  • the entrainment cues include a rhythmic component associated with a target respiration rate.
  • US patent application US 2021/330910 Al discloses systems for hyperarousal disorder such as for determining settings that control respiratory therapy for slowing a patient’s breathing. They may be configured to determine an interim target breathing rate less than a current spontaneous rate. They may be configured to derive target inspiratory time and expiratory times based on the interim target breathing rate.
  • US patent application US 2008/035147 Al discloses a method for providing breathing cues that includes monitoring respiration of a user and determining a user breathing frequency including an inspiration portion and an expiration portion of the breathing.
  • the computer-implemented method comprises obtaining a recorded length for each of at least two different segments in a sample breathing cycle of the individual, each recorded length being the length of a respective segment in the sample breathing; obtaining a sample breathing rate of the individual; obtaining a desired breathing rate for the individual; and determining, for a further breathing cycle of the individual, for at least one of the at least two different segments, a target length by processing the recorded length for said segment, the desired breathing rate for the individual, and the sample breathing rate for the individual, wherein the target length for said segment is proportional to the recorded length for said segment; and generating a control signal for the output device to provide a user-perceptible output for guiding the individual to breathe, in accordance with the target length.
  • Embodiments provide a technique for paced or guided breathing, in which the length of a segment of the paced breathing is controlled to be proportional to the length of the respective segment during a sample breathing cycle (i.e., an initial breathing cycle before paced breathing is provided).
  • the proposed approach provides a more natural breathing cycle for the individual, as it will more closely match the rhythm of their own breathing cycle. This increases a likelihood of adherence to the paced breathing cycle, increased for an individual in following paced breathing guidance and improved outcomes for the individual undergoing paced breathing.
  • the computer-implemented method may comprise that the at least two different segments comprise an inhalation segment, an exhalation segment and at least one breath holding segment.
  • a ratio between the target length of the inhalation segment and the recorded length of the inhalation segment is greater than a ratio between the target length of said breath holding segment and the recorded length of said breath holding segment; and/or a ratio between the target length of the exhalation segment and the recorded length of the exhalation segment is greater than a ratio between the target length of said breath holding segment and the recorded length of said breath holding segment.
  • the target length is proportional to the recorded length for said segment multiplied by a ratio of the sample breathing rate and the desired breathing rate.
  • At least two different segments comprise at least one breath holding segment. This approach recognizes that a natural breath cycle of an individual will contain a breath hold, allowing for improved control and adherence for paced breathing guidance.
  • At least one breath holding segment comprises at least one of a postinhalation breath holding segment and a post-exhalation breath holding segment.
  • the target length is the same as the recorded length of the sample breathing cycle. This approach recognizes that holding of a breath may be difficult or disruptive to an individual undergoing paced breathing guidance. By setting the target length of a breath holding segment to be the same as that of a sample breathing cycle, this disruption is advantageously avoided whilst still facilitating a change to the breathing rate of the individual.
  • the difference between the target length and the recorded length is non-zero.
  • the target length is proportional to the recorded length for said segment multiplied by a ratio of the sample breathing rate and the desired breathing rate.
  • the target length is proportional to a weight that changes responsive to the sampled breathing rate. For example, user may have longer or shorter target length for the breach holding segment when the user’s breath rate is lower. Hence, a weight can be added to realize the adjustment of the target length.
  • the at least two different segments comprise an inhalation segment and an exhalation segment. This facilitates control or guidance over two known segments of a breathing cycle of the individual.
  • a ratio between the target length of the inhalation segment and the recorded length of the inhalation segment is greater than a ratio between the target length of said breath holding segment and the recorded length of the breath holding segment; and/or a ratio between the target length of the exhalation segment and the recorded length of the exhalation segment is greater than a ratio between the target length of said breath holding segment and the recorded length of the breath holding segment.
  • a ratio between the target length of the inhalation segment and the recorded length of the inhalation segment is the same as a ratio between the target length of said breath holding segment and the recorded length of said breath holding segment; and/or a ratio between the target length of the exhalation segment and the recorded length of the exhalation segment is the same as a ratio between the target length of said breath holding segment and the recorded length of said breath holding segment.
  • the target lengths of each segment are proportional to the recorded length for said segment multiplied by a ratio of the sample breathing rate and the desired breathing rate.
  • the target length is proportional to the recorded length for said segment multiplied by a ratio of the sample breathing rate and the desired breathing rate.
  • the method comprises obtaining a recorded length for all segments in the sample breathing cycle; determining a target length for all segments in the sample breathing cycle, wherein the sum of all target lengths, when defined in seconds, is equal to 60 times the reciprocal of the desired breathing rate, when defined in breaths per minute.
  • the step of obtaining a desired breathing rate comprises obtaining a desired breathing rate for each segment for a of the plurality of further breathing cycles of the individual; and for each of the plurality of further breathing cycles, the step of determining a target length for each segment comprises processing the recorded length for said segment, the desired breathing rate for the breathing cycle of the individual, and the sample breathing rate for the individual, wherein the target length for said segment is proportional to the recorded length for said segment.
  • This technique allows for an evolution or change of the paced breathing guidance over time, for instance, to allow a gradual transition of the paced breathing towards a final target breathing rate over at least one of the plurality of further breathing cycles.
  • the desired breathing rate initially starts at the sample breathing rate and gradually changes to a target breathing rate.
  • a computer program product comprising computer program code means which, when executed on a computing device having a control system, cause the control system to perform all of the steps of any herein disclosed method.
  • a system for providing paced breathing guidance to an individual comprising an output device for providing user-perceptible outputs to an individual and a control system.
  • the control system is configured to perform the computer-implemented method according to an aspect of the invention.
  • the control system is configured to obtain a recorded length for each of at least two different segments in a sample breathing cycle of the individual, each recorded length being the length of a respective segment in a sample breathing cycle of the individual; obtain a sample breathing rate of the individual; obtain a desired breathing rate for the individual; and determining, for a further breathing cycle of the individual, for at least one of the at least two different segments, a target length by processing the recorded length for said segment, the sample breathing rate and the desired breathing rate for the individual, wherein the target length for said segment is proportional to the recorded length for said segment; and generate a control signal for the output device to provide a user-perceptible output for guiding the individual to breathe, for the breathing cycle, in accordance with the target length.
  • FIG. 1 illustrates a system in which embodiments can be employed
  • Fig. 2 conceptually illustrates a breathing cycle
  • Fig. 3 is a flowchart illustrating a proposed method
  • Fig. 4 illustrates a display for obtaining recorded lengths of different segments of a sample breathing cycle.
  • the invention provides a mechanism for guiding the length of a plurality of different segments of a plurality of breathing cycles.
  • a recorded length of each of the plurality of segments in a sample breathing cycle is obtained.
  • the recorded length of each segment is used, together with a sample breathing rate and a desired breathing rate, to define a target length of each segment in each of a plurality of breathing cycles.
  • Each target length is proportional to the corresponding recorded length.
  • Embodiments are based on the recognition that different individuals will have different rhythms to their breathing cycles. Compliance or adherence to paced breathing guidance is more difficult if the rhythm of the individual’s breathing does not match that of the paced breathing guidance. By controlling segments of paced breathing cycles to be proportional to recorded length(s) of said segments, an ease of following paced breathing is increased.
  • Proposed approaches find particular advantage in guided sleep scenarios, but can be employed in any circumstance in which paced breathing guidance is desired.
  • Fig. 1 illustrates a system 100 in which embodiments can be employed, for improved contextual understanding.
  • the system 100 comprises a control system 110 and an output device 190.
  • the output device 190 is here configured to controllably provide a user-perceptible output for providing paced or guided breathing to an individual.
  • the control system 110 defines or controls the operation of the output device, as later described.
  • output device 190 could be used to provide a user- perceptible output.
  • the output device 190 is configured to provide tactile guidance of breathing for an individual. In this way, the output device 190 is able to provide a user-perceptible output in the form of a tactile output for paced or guided breathing.
  • the output device 190 here comprises a moveable member 191 that is able to move to guide the breathing of an individual.
  • the moveable member 191 can therefore be controlled to move to provide the tactile guidance to the individual, i.e., provide a tactile output to the individual.
  • the moveable member 191 may move or fluctuate a surface of the output device according to a desired breathing rate and/or pattern, to guide the individual to follow the breathing rate and/or pattern.
  • a moveable member 191 is an airbag with controllable inflation and deflation.
  • Another example is a piston-based system for providing tactile feedback.
  • Yet another example is a motor-driven paddle.
  • Other examples will be apparent to the skilled person.
  • the output device may be formed as a (huggable) pillow or cushion, e.g., with a soft surface material. This is natural for an individual to hug or squeeze when preparing to sleep or when falling asleep, to ensure that the output device is able to provide the tactile feedback in a natural manner. However, this is not essential.
  • the output device may be a hand-held device that can be squeezed or held in the hand, e.g., a soft toy, stress ball or the like.
  • a moveable member for facilitating the provision of paced or guided breathing to an individual using a user-perceptible output
  • a moveable member is a screen configured to provide a visual output that can be used to provide paced/guided breathing (e.g., using a pulsating icon or the like).
  • a speaker or buzzer for providing an audible output that can be used to provide paced/guided breathing.
  • the output device may also comprise a device control system 192, configured to control the operation of the output device (e.g., the moveable member, screen or speaker).
  • the device control system 192 may, for instance, comprise a microcontroller and/or other control logic for controlling the operation of output device 190.
  • the control system 110 is configured to control or define the operation of the output device 190.
  • the control system 110 here comprises an input control interface 111, a data processor 112 and an output control interface 113.
  • the data processor 112 of the control system 110 is configured to control the operation of the output device 190 via the output control interface 113.
  • the output control interface 113 is communicatively coupled to the output device to control the operation thereof.
  • the output control interface 113 may be communicatively coupled to the device control system 192, to control the operation of the output device using the capabilities of the device control system 192, e.g., using a control signal Sc.
  • the control system may control the operation of the device control system 192 by providing instructions for execution by the device control system.
  • the communication between the output control interface 113 and the output device 190 may be wired or wireless.
  • Suitable wireless communication protocols that may be used to communicate with the tactile breathing guidance device 190 include an infrared link, Zigbee, Bluetooth, a wireless local area network protocol such as in accordance with the IEEE 802. 11 standards, a 2G, 3G, 4G or 5G telecommunication protocol, and so on.
  • Other formats will be readily apparent to the person skilled in the art.
  • the control system 110 is configured to determine a target length for each of a plurality of segments of a plurality of breathing cycles.
  • the control system 110 controls the output device to provide a user-perceptible output to breathe, for each breathing cycle, in accordance with the target length of each of the at least two different segments.
  • Fig. 2 is a Figure that illustrates a single breathing cycle 200 of an individual.
  • An x-axis represents time t (e.g., in seconds) and a y-axis represents volume V of air (e.g., in m 3 ) in the individual’s lungs.
  • a breathing cycle 200 can be conceptually divided into a plurality of different segments.
  • a segment is therefore a part or portion of a breathing cycle.
  • the plurality of segments may include at least an inhalation segment 210 (where an individual is breathing in) and an exhalation segment 230 (where the individual is breathing out).
  • the breathing cycle 200 may further include at least one breath holding segment 220, 240.
  • a breath holding segment may be labelled an inhalation breath holding segment 220, which takes place between an inhalation 210 and exhalation 230 segment.
  • Another example of a breath holding segment may be labelled an exhalation breath holding segment 240, which takes place after an exhalation segment 230, and before the next breathing cycle.
  • One or both of the inhalation and exhalation breath holding segments can be omitted in some scenarios.
  • a breathing cycle may comprise a plurality of inhalation segments, e.g., a first inhalation segment during which a volume of air increases at a first rate, and a second inhalation segment, during which a volume of air increases at a second, different rate.
  • a breathing cycle may comprise a plurality of temporally separated inhalation segments, e.g., separated by one or more breath holding segments and/or exhalation segments.
  • a breathing cycle 200 may comprise one or more inhalation segments 210, one or more exhalation segments 230 and (optionally) one or more breath holding segments 220, 240.
  • the precise arrangement of a breathing cycle may, for instance, be dependent upon a specific individual and/or a desired paced breathing guidance for the individual, e.g., to target deep inhalation or deep exhalation for certain medical conditions or pathologies.
  • the present invention proposes a technique for determining a target length for a plurality of different segments of a plurality of breathing cycles.
  • a user-perceptible output (provided by an output device) is then controlled to guide an individual to breath in accordance with the determined target lengths.
  • the present disclosure provides a technique for setting a target length that makes use of recorded lengths of a sample breathing cycle of the individual. This allows the target lengths of each segment to be turned to the sample breathing cycle to more closely match the rhythm or pattern of breathing of the individual. This increases a likelihood of compliance.
  • the output device may be controlled to control the timings of different forms of feedback or user-perceptible outputs responsive to the target lengths of each segment.
  • the target length of each segment may define for how long a first form of feedback or user- perceptible output is provided until said form of feedback is ended.
  • the timing of different forms of feedback may be sequentially controlled in accordance with the target length of each segment.
  • a movement (or non-movement) of the moveable member may be controlled to correspond to a length of a breathing segment.
  • movement in a first direction may represent an inhalation segment
  • a lack of movement may represent a breath holding segment
  • a movement in a second (different) direction may represent an exhalation segment.
  • a pitch of a tone emitted by the speaker may be controlled to correspond to a particular segment. For instance, an increasing pitch may represent an inhalation segment, a maintained pitch may represent a breath holding segment and a decreasing pitch may represent an exhalation segment.
  • an appearance of an icon may be modified responsive to a segment.
  • the icon may be: expanded in size during an inhalation segment; maintained in size during a breath holding segment; and reduced in size during an exhalation segment.
  • Other suitable examples e.g., color changing icons or the like
  • Fig. 3 is a flowchart that illustrates a method 300 for providing paced breathing guidance to an individual.
  • the method 300 makes use of the proposed technique(s) in order to provide the paced breathing.
  • the method 300 comprises a step 310 of obtaining a recorded length for at least two different segments of a breathing cycle.
  • Each recorded length is the monitored or determined length of a respective segment in a sample breathing cycle of the individual.
  • a sample breathing cycle represents a historic or ground-truth breathing cycle of the individual (i.e., a breathing cycle that actually occurred).
  • the length of a segment may be defined as a measure of time, e.g., in seconds, milliseconds or using other suitable unit of time.
  • An alternative label for a length of a segment is therefore a period.
  • the method 300 also comprises a step 320 of obtaining a sample breathing rate.
  • a sample breathing rate represents a current, historic or previous breathing rate (e.g., in breaths per unit time) of the individual.
  • the sample breathing cycle used to determine the recorded length may, for instance, be one (or an average) of the breathing cycles used in determining the sample breathing rate.
  • the method 300 also comprises a step 330 of obtaining a desired breathing rate.
  • the desired breathing rate represents a target or desirable breathing rate for the individual, e.g., according to a particular paced breathing guidance protocol, a user-defined desired breathing rate or any other form of predetermined desired breathing rate.
  • the precise mechanism by which a desired breathing rate is defined or obtained is immaterial to the underlying inventive concept.
  • the method 300 also comprises a step 340 of determining, for a plurality of (future/guided) breathing cycles, a target length for at least one of the at least two different segments of the breathing cycle.
  • each of the plurality of breathing cycles is a different future or guided breathing cycle for the individual.
  • the plurality of breathing cycles may be temporally adjacent to one another, e.g., to form a sequence or series of breathing cycles for paced breathing guidance.
  • the plurality of breathing cycles may comprise a sequence or series of breathing cycles, more particularly a sequence or series of paced breathing cycles for paced breathing guidance.
  • Step 340 comprises processing the recorded lengths, the sample breathing rate and the desired breathing rate to determine the target length.
  • each target length may be determined by processing at least the corresponding recorded length (for the same segment of a breathing cycle), the sample breathing rate and the desired breathing rate.
  • the target length is proportional to the recorded length for said segment.
  • step 340 A number of example approaches for performing step 340 will be described later in this disclosure. Some described approaches share a same common recognition that the target length of a segment should be controlled to be proportional (i.e., calculated via multiplication) of the recorded length of the segment.
  • the method 300 also comprises a step 350 of controlling, for each of the plurality of (future/guided) breathing cycles, the output device to provide a user-perceptible output for guiding the individual to breathe, for said breathing cycle, in accordance with the target length for each of the at least two different segments.
  • Step 350 may comprise controlling the user-perceptible output through a sequence of different states or forms, each representing a different segment of the breathing cycle.
  • the length during which the user-perceptible output is held in each state is controlled to be equal to the target length, to thereby provide paced breathing in accordance with the target length for each of the at least two different segments.
  • step 350 may change a user-perceptible output to follow a sequence of segments, each having target lengths.
  • the state/form of a user-perceptible output should therefore differ between adjacent segments. Non-adjacent segments (e.g., breath holding segments separated by an inhalation/exhalation segment) may share a same user-perceptible output.
  • the step 330 of obtaining a desired breathing rate comprises obtaining a same (i.e., single) desired breathing rate for each of the plurality of (future) breathing cycles.
  • the step 330 of obtaining a desired breathing rate comprises obtaining a different desired breathing rate for each segment of each of the plurality of breathing cycles.
  • the step 330 obtaining a desired breathing rate may comprise obtaining a desired breathing rate for each segment of each of the plurality of breathing cycles of the individual.
  • the step of determining a target length for each segment may comprises processing the recorded length for said segment, the desired breathing rate for the breathing cycle of the individual, and the sample breathing rate for the individual.
  • the target length for said segment will remain proportional to the recorded length for said segment.
  • the above approach allows, for instance, for the paced breathing guidance to gradually or incrementally change the guided breathing provided to the individual (in step 350).
  • the desired breathing rate may gradually reduce for successive breathing cycles, to encourage a gradual reduction in the breathing rate of the individual.
  • the desired breathing rate for each of the plurality of breathing cycles initially starts at the sample breathing rate and gradually (i.e., sequentially with the plurality of breathing cycles) changes to a target breathing rate.
  • a target breathing rate may, for instance, be an ultimate goal of the paced breathing guidance.
  • the plurality of breathing cycles comprises a sequence of no fewer than 10 breathing cycles, with the desired breathing rate for each breathing cycle sequentially decreasing through the sequence.
  • the difference between the desired breathing rate of each breathing cycle in the sequence may be equal (for example) to a first value, being a difference between the sample breathing rate and the target breathing rate, divided by the total number of breathing cycles in the sequence. This provides an even and gradual decrease in the desired breathing rate output to the individual.
  • a desired breathing rate may reduce at a first speed for a first set/sequence of breathing cycles before reducing at a second speed for a second set/sequence of breathing cycles.
  • each calculated time allocation for each segment will start from the beginning of next breath cycle.
  • the previously calculated segment lengths will still be valid for the rest of the breath cycle.
  • step 340 is performed by determining the target length of at least one segment of each of the plurality of breathing cycles by adjusting or defining the length of each segment proportionally to the ratio of the sample breathing rate and the desired breathing rate. More particularly, each segment may be controlled to be proportional to the recorded length for said segment multiplied by the ratio of the sample breathing rate and the desired breathing rate.
  • the target length TTS of at least one of, any and/or each given segment in a (future/guided) breathing cycle may be calculated using the following equation: where Rs is the sample breathing rate; RT is the desired breathing rate for the breathing cycle (both of which are defined in breaths per minute) and TRS is the recorded length of the segment in the sample breathing cycle.
  • the desired breathing rate may differ for different (future/guided) breathing cycles of the individual.
  • Equation (1) is functionally equivalent to the following equation: where TT is the total length of a target breathing cycle that achieves the desired breathing rate and TR is the total recorded length of the sample breathing cycle.
  • step 340 is performed by setting the target length for each a first subset of one or segments to be the same as its corresponding recorded length and setting the target length for each other segment (not in the first subset) to be proportional to the ratio of the sample breathing rate and the desired breathing rate (i.e., proportional to Rs RT).
  • the target length of each segment in the first subset of one or more segments may be held at the recorded target length.
  • the target length of each breath holding segment of a breathing cycle may be maintained at the recorded length of said breathing hold segment.
  • the target length of each breath holding segment may be held at the recorded target length of said breath holding segment.
  • the target length of each other segment may be proportionally controlled, e.g., so that the ratio between any pair of other segments remains the same as during the sample breathing cycle.
  • the target lengths of the segments, which are not part of the first subset of one or more segments are controlled so that overall length of the breathing cycle achieves the desired breathing rate.
  • the target lengths of those segments not in the first subset of one or more segments contribute 100% of the modification(s) to target the desired breathing rate.
  • Equation (3) is functionally equivalent to the following equation:
  • TTS T _ T ’ RS (4)
  • step 340 is performed by setting, for each of a plurality of subsets of one or more segments, the target length for each segment in that subset such that the segment contributes a particular percentage to the change in the total length of the breathing cycle to achieve the desired breathing rate.
  • the target length of segments in a same subset may be maintained to be proportional to one another.
  • the length of each a second subset of segments of a breathing cycle may be modified such that the second subset contributes X% (e.g., 20%) to the change of the total length of the breathing cycle to achieve the desired breathing rate
  • a third subset of segments of the breathing cycle e.g., the inhalation and exhalation segments
  • the target length of each segment remains proportional to the recorded length of said segment, with different weights being applied to the segment dependent upon to which subset said segment belongs.
  • the value of X may be defined or determined by a user via a user interface, or may be predetermined based on pre-test results from several tested individuals. In some examples, the value of X is between 5 and 40, e.g., between 10 and 30, e.g., 20.
  • the breath holding segments are adjusted slightly, whilst inhalation and exhalation segments will be adjusted heavily.
  • inhalation hold segment and exhalation hold segment may be adjusted by 20%, while inhalation and exhalation segments may be adjusted by 80%.
  • the target length for each breath holding segment may be proportional to a weight that changes responsive to the sampled breathing rate.
  • the target length for each breathing holding segment may be changed differently depending upon the sampled breathing rate. This, for instance, allows a different ratio to be used for breath holding segments when the sample breathing rate is lower compared to when the sample breathing rate is higher.
  • a weight can be applied to (e.g., used to multiply) the ratio for breath holding segments to compensate the formula (for the first or third approaches).
  • a value of the weight is responsive to the sampled breathing rate, e.g., may switch between or have different values dependent upon the sampled breathing rate.
  • Suitable values for the weight can be defined by pre-test of several test subjects or may be defined via a user interface. For instance, the pre-rest or user interface definition may define one or more ranges for the sampled breathing rate, each associated with a different weight to be applied to the ratio for the breath holding segments. Other suitable approaches for defining the relationship between a sampled breathing rate and a value of a weight will be apparent to the suitably skilled person.
  • a breath holding segment may have a maximum change of no more than 25%.
  • a breath holding segment may have a maximum change of no more than 50%.
  • a user or other individual may directly input or record the lengths of each segment.
  • an individual who is not necessarily the same individual for which paced breathing guidance is to be provided, can monitor the length of breathing segments of a sample breathing cycle (e.g., using a stopwatch or the like) and input the monitored lengths into a user interface to provide the recorded length of the segments.
  • an interactive user interface may be provided that enables an individual to mark points labelling the start and/or end points of different segments.
  • Fig. 4 conceptually illustrates one example of a display 400 of a user interface that allows an individual to record or mark the recorded lengths for each of a plurality of segments of a sample breathing cycle.
  • a control program (such as a mobile application running on a mobile device with touchable display) provides or presents a display 400 at a user interface to the individual.
  • the user interface may, for instance, provide a visual representation or display 400 of a normal breath 405 conceptually divided into different breath segments (“Inhale”, “Hold”, “Exhale”, “Hold”).
  • Each breath segment may be associated with two touch points 410, 420, 430, 440, 450 or interactive buttons, that identifying the start and/or end of the breath segment.
  • an “Inhale” breath segment may be associated with a first and second touch point.
  • adjacent breath segments may share a single touch point, e.g., to end one segment and start the next.
  • the control program may guide or instruct the user to take a normal breath, and during breathing, the user will move through and touch the touch points of each breath segment as they breathe according to the breath segments.
  • a user inhales, they may move from the first touch point 410 to the second touch point 420.
  • a third touch point 430 As the user holds their breath, they may move from the second touch point 420 to a third touch point 430.
  • An internal timer may monitor and record the times at which the individual touches a touch point one by one. With each recorded timestamp, the program will then be able calculate the time of each breath segment, i.e., the time difference between touching the two touch points associated with the breath segment.
  • An alternative approach to using a plurality of touch points for each segment is to simply provide an interactive user interface with which the user engages or interacts (e.g., presses and releases) to indicate the start/end of a breathing segment. For instance, a user may interact with the user interface to indicate the initiation of an inhale, before disengaging with the user interface to indicate a breath hold, before engaging again with the user interface to indicate an exhale, before disengaging again to indicate another breath hold, before engaging again to indicate an end to the breath hold.
  • breath or respiratory sensor that directly monitors the breathing of the individual.
  • Such a sensor would be able to monitor for different breath segments, e.g., by monitoring for movement or other characteristic changes that represent a movement through a breathing cycle.
  • breath sensors are well known in the art, such as those that directly monitor a (physical) movement of the chest or abdomen or those that monitor a visual motion of the chest/abdomen (e.g., using a camera). Yet other approaches monitor a fogging or defogging of a mask worn by the individual. Yet other approaches make use of microphones to monitor a sound of different breathing segments.
  • a wide variety of different respiratory monitoring systems are known in the art, any of which can be employed in the present invention. Some examples techniques are set out in Vanegas, Erik, Raul Igual, and Inmaculada Plaza. "Sensing systems for respiration monitoring: A technical systematic review.” Sensors 20.18 (2020): 5446. Others will be readily apparent to the skilled person.
  • the sample breathing rate for obtaining in step 220, can be trivially determined by multiplying 60 seconds with the reciprocal of the sum of all the recorded lengths for all segments of the sample breathing cycle.
  • the sample breathing rate can be separately recorded or monitored, e.g., using standard respiratory rate monitoring mechanisms or techniques.
  • each step of the flow chart may represent a different action performed by a control system, and may be performed by a respective module of the control system.
  • Embodiments may therefore make use of a control system.
  • the control system can be implemented in numerous ways, with software and/or hardware, to perform the various functions required.
  • a processor is one example of a control system which employs one or more microprocessors that may be programmed using software (e.g., microcode) to perform the required functions.
  • a control system may however be implemented with or without employing a processor, and also may be implemented as a combination of dedicated hardware to perform some functions and a processor (e.g., one or more programmed microprocessors and associated circuitry) to perform other functions.
  • control system components that may be employed in various embodiments of the present disclosure include, but are not limited to, conventional microprocessors, application specific integrated circuits (ASICs), and field-programmable gate arrays (FPGAs).
  • ASICs application specific integrated circuits
  • FPGAs field-programmable gate arrays
  • a processor or control system may be associated with one or more storage media such as volatile and non-volatile computer memory such as RAM, PROM, EPROM, and EEPROM.
  • the storage media may be encoded with one or more programs that, when executed on one or more processors and/or control systems, perform the required functions.
  • Various storage media may be fixed within a processor or control system or may be transportable, such that the one or more programs stored thereon can be loaded into a processor or control system.
  • the output device is controllable to provide user-perceptible outputs that can be used to provide paced breathing guidance. More particularly, the control system may be configured to control the operation of the output device in order to controllably provide a user- perceptible output for providing paced breathing guidance in accordance with the target lengths of different segments of a breathing cycle.
  • Non-transitory storage medium that stores or carries a computer program or computer code that, when executed by a control system, causes the control system to carry out any herein described method.
  • a single processor or other unit may fulfill the functions of several items recited in the claims.
  • the mere fact that certain measures are recited in mutually different dependent claims does not indicate that a combination of these measures cannot be used to advantage.
  • a computer program may be stored/distributed on a suitable medium, such as an optical storage medium or a solid-state medium supplied together with or as part of other hardware, but may also be distributed in other forms, such as via the Internet or other wired or wireless telecommunication systems.

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Abstract

L'invention concerne un mécanisme de guidage de la longueur d'une pluralité de segments différents d'une pluralité de cycles respiratoires. Une longueur enregistrée de chacun de la pluralité de segments dans un cycle respiratoire échantillon est obtenue. La longueur enregistrée de chaque segment est utilisée, conjointement avec une fréquence respiratoire d'échantillon et une fréquence respiratoire souhaitée, pour définir une longueur cible de chaque segment dans chacun d'une pluralité de cycles respiratoires. Chaque longueur cible est proportionnelle à la longueur enregistrée correspondante.
PCT/EP2024/060462 2023-04-27 2024-04-18 Fourniture de guidage respiratoire à un individu WO2024223385A1 (fr)

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CNPCT/CN2023/091158 2023-04-27
CN2023091158 2023-04-27
EP23179491.8 2023-06-15
EP23179491 2023-06-15

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080035147A1 (en) 2006-08-11 2008-02-14 Todd Kirby Systems and Methods for Controlling Breathing Rate
US20190030278A1 (en) 2017-07-26 2019-01-31 Bose Corporation Entraining respiration
WO2019240778A1 (fr) * 2018-06-12 2019-12-19 Vardas Solutions LLC Procédés et systèmes pour administrer un rythme respiratoire étalonné à une fréquence de résonance
US20210330910A1 (en) 2018-02-15 2021-10-28 ResMed Pty Ltd Method and apparatus for treating hyperarousal disorder

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080035147A1 (en) 2006-08-11 2008-02-14 Todd Kirby Systems and Methods for Controlling Breathing Rate
US20190030278A1 (en) 2017-07-26 2019-01-31 Bose Corporation Entraining respiration
US20210330910A1 (en) 2018-02-15 2021-10-28 ResMed Pty Ltd Method and apparatus for treating hyperarousal disorder
WO2019240778A1 (fr) * 2018-06-12 2019-12-19 Vardas Solutions LLC Procédés et systèmes pour administrer un rythme respiratoire étalonné à une fréquence de résonance

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