WO2023068955A1 - Method of acoustically analysing the state of an organism - Google Patents
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- WO2023068955A1 WO2023068955A1 PCT/RU2021/000444 RU2021000444W WO2023068955A1 WO 2023068955 A1 WO2023068955 A1 WO 2023068955A1 RU 2021000444 W RU2021000444 W RU 2021000444W WO 2023068955 A1 WO2023068955 A1 WO 2023068955A1
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- 238000000034 method Methods 0.000 title claims abstract description 18
- 238000004458 analytical method Methods 0.000 claims description 7
- 210000002216 heart Anatomy 0.000 claims description 5
- 210000004072 lung Anatomy 0.000 claims description 3
- 210000001835 viscera Anatomy 0.000 claims description 3
- 210000004204 blood vessel Anatomy 0.000 claims description 2
- 230000005236 sound signal Effects 0.000 claims description 2
- 210000001519 tissue Anatomy 0.000 claims 1
- 230000035935 pregnancy Effects 0.000 abstract description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 4
- 239000003814 drug Substances 0.000 abstract description 4
- 238000012544 monitoring process Methods 0.000 abstract description 3
- 230000007547 defect Effects 0.000 abstract description 2
- 238000013399 early diagnosis Methods 0.000 abstract description 2
- 230000007170 pathology Effects 0.000 abstract description 2
- 238000002604 ultrasonography Methods 0.000 abstract description 2
- 208000019693 Lung disease Diseases 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 208000019553 vascular disease Diseases 0.000 abstract 1
- 238000004891 communication Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 210000003754 fetus Anatomy 0.000 description 3
- 230000003321 amplification Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000003199 nucleic acid amplification method Methods 0.000 description 2
- 208000001871 Tachycardia Diseases 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 210000002458 fetal heart Anatomy 0.000 description 1
- 238000010295 mobile communication Methods 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 230000006794 tachycardia Effects 0.000 description 1
- 210000003954 umbilical cord Anatomy 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
Definitions
- the invention relates to the field of medicine, and more specifically to a method for acoustic analysis of the state of the organism.
- the present invention can be used to create new generation diagnostic systems in medicine, as well as to create socially oriented systems for early diagnosis of diseases of the heart, blood vessels and lungs, as well as for monitoring pregnancy.
- the present invention is based on the task of creating such a method of acoustic analysis of the state of the body, which would allow predicting the onset of critical events in the body, primarily associated with internal diseases, or a critical increase in any values of indicators describing pulmonary, cardiological and vascular processes in body.
- patent RU2644546 C1 ELECTRONIC MEDICAL STETHOSCOPE discloses an electronic medical stethoscope containing a piezoelectric type acoustic receiver connected to a matching stage, which is connected to an amplification and filtering device, a block of reference phonograms and an analysis block, a touch switch and an analog-to-digital converter, characterized in that the amplification device includes and filtering includes a low-noise amplifier, four bandpass filters, an adjustable power preamplifier and a power supply filter, and the output of the low-noise amplifier is connected to the first inputs of four bandpass filters connected in parallel, with bandwidths of 15-1000 Hz at the first, 100-500 Hz for the second, 15-2500 Hz for the third and 20-16000 Hz for the fourth, the outputs of the band-pass filters are connected to the input of an adjustable pre-amplifier, which is connected to the input of the final power amplifier, the second output of which is connected
- the objectives of the invention are solved and the disadvantages of the prototype are eliminated in the method of acoustic analysis of the state of the body implemented according to the present invention, which consists in receiving acoustic signals from an acoustic microphone array for a long time fixed on the body and consisting of rows of microphones, several microphones in a row and containing at least two rows of microphones and at least two microphones in a row, set the properties of the signals received from all microphones, including, but not limited to, signal amplitude, phase and frequency, Doppler shift, and the location of the signal source, including the location of the reflection of sound waves, including from the internal organs, tissues and vessels of the body, after which the received signals are stored, the range of signal properties is selected, which is considered normal, and a deviation of the parameters from the normal is signaled, indicating audio source for which deviation from normal is set.
- the present invention will be disclosed in the following description of a belt for determining the state of the body of the mother and fetus during pregnancy, containing an array of three rows of microphones with seven microphones in a row.
- acoustic signals are received from an acoustic microphone array fixed on the body of a pregnant woman for a long time, the properties of the signals received from all microphones are established, first of all, receiving signals from the heart of the mother and fetus and establishing the location of the signal source, including the place where sound waves are reflected, in including from the internal organs, tissues and vessels of the body of the mother and fetus.
- the received signals are stored, a range of signal properties is selected, which is considered normal, and a deviation of the parameters from the normal is signaled, indicating the source of the sound signal for which the deviation from the normal is set.
- this is the loss of the fetal pulse, clamping of the umbilical cord, arrhythmia and tachycardia of the mother's heart.
- the claimed method has high versatility, constancy and flexibility, unlike ultrasound, it is harmless, allows you to achieve better results, is universal for various types of diseases, does not depend on movement, allows you to quickly identify the appearance of pathologies and defects in the body, allows to classify the processes of the onset of critical events in the body according to the intensity and nature of the signals, including the state of pregnancy.
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- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
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- Medicinal Chemistry (AREA)
- Radiology & Medical Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
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Abstract
The invention relates to the field of medicine, and more particularly to a method of acoustically analysing the state of an organism. The present invention can be used in the creation of next-generation diagnostic systems for use in medicine, as well as in the creation of community-based systems for the early diagnosis of heart diseases, vascular diseases and lung diseases, as well as for monitoring pregnancy. By comparison with other known methods, the claimed method is highly versatile, consistent and flexible, is not harmful like ultrasound, makes it possible to obtain better results, is universally applicable to different types of disorders, does not rely on movement, makes it possible to quickly identify the onset of pathologies and defects in an organism, and makes it possible to classify processes indicative of critical events in an organism, inter alia pregnancy, according to the intensity and nature of signals.
Description
СПОСОБ АКУСТИЧЕСКОГО АНАЛИЗА СОСТОЯНИЯ ОРГАНИЗМА. METHOD FOR ACOUSTIC ANALYSIS OF ORGANISM STATE.
ОПИСАНИЕ. DESCRIPTION.
Изобретение относится к области медицины, а более конкретно - к способу акустического анализа состояния организма. The invention relates to the field of medicine, and more specifically to a method for acoustic analysis of the state of the organism.
Настоящее изобретение может найти применение при создании диагностических систем нового поколения в медицине, а также для создания социально-ориентированных систем ранней диагностики заболеваний сердца, сосудов и легких, а также при мониторинге беременности. The present invention can be used to create new generation diagnostic systems in medicine, as well as to create socially oriented systems for early diagnosis of diseases of the heart, blood vessels and lungs, as well as for monitoring pregnancy.
В основу настоящего изобретения положена задача создания такого способа акустического анализа состояния организма, который позволил бы предсказывать наступление критических событий в организме, в первую очередь, связанных с внутренними заболеваниями, либо критическим ростом каких-либо значений показателей, описывающих легочные, кардиологические и сосудистые процессы в организме. The present invention is based on the task of creating such a method of acoustic analysis of the state of the body, which would allow predicting the onset of critical events in the body, primarily associated with internal diseases, or a critical increase in any values of indicators describing pulmonary, cardiological and vascular processes in body.
Наиболее близким к данному изобретению является патент RU2644546 С1 ЭЛЕКТРОННЫЙ МЕДИЦИНСКИЙ СТЕТОСКОП. В данном изобретении раскрыт электронный медицинский стетоскоп, содержащий акустический приемник пьезоэлектрического типа, соединенный с согласующим каскадом, который соединен с устройством усиления и фильтрации, блок эталонных фонограмм и блок анализа, сенсорный переключатель и аналого-цифровой преобразователь, отличающийся тем, что в состав устройства усиления и фильтрации входят малошумящий усилитель, четыре полосовых фильтра, регулируемый предварительный усилитель мощности и фильтр цепи питания, причем выход малошумящего усилителя соединен с первыми входами четырех полосовых фильтров, соединенных по параллельной схеме, с полосами пропускания 15-1000 Гц у первого, 100-500 Гц у второго, 15-2500 Гц у третьего и 20-16000 Гц у четвертого, выходы полосовых фильтров подключены к входу регулируемого предварительного усилителя мощности, который подключен к входу оконечного усилителя мощности, второй выход которого соединен с
головными телефонами, а первый выход последовательно соединен с аналого- цифровым преобразователем, контроллером, приемопередатчиком устройства беспроводной связи, причем выход приемопередатчика устройства беспроводной связи соединен с входами гарнитуры устройства беспроводной связи, мобильным терминалом связи и персональным компьютером, второй вход контроллера соединен с блоком анализа, выход которого соединен с входом блока эталонных фонограмм, автономный источник питания, своим выходом подключенный к сенсорному переключателю, выход которого соединен с фильтром цепи питания, который соединен с переключателем режимов для коммутации малошумящего усилителя с входами первого, второго, третьего и четвертого полосовых фильтров. Closest to this invention is patent RU2644546 C1 ELECTRONIC MEDICAL STETHOSCOPE. This invention discloses an electronic medical stethoscope containing a piezoelectric type acoustic receiver connected to a matching stage, which is connected to an amplification and filtering device, a block of reference phonograms and an analysis block, a touch switch and an analog-to-digital converter, characterized in that the amplification device includes and filtering includes a low-noise amplifier, four bandpass filters, an adjustable power preamplifier and a power supply filter, and the output of the low-noise amplifier is connected to the first inputs of four bandpass filters connected in parallel, with bandwidths of 15-1000 Hz at the first, 100-500 Hz for the second, 15-2500 Hz for the third and 20-16000 Hz for the fourth, the outputs of the band-pass filters are connected to the input of an adjustable pre-amplifier, which is connected to the input of the final power amplifier, the second output of which is connected to headphones, and the first output is connected in series with an analog-to-digital converter, a controller, a transceiver of the wireless communication device, and the output of the transceiver of the wireless communication device is connected to the headset inputs of the wireless communication device, a mobile communication terminal and a personal computer, the second input of the controller is connected to the analysis unit, the output of which is connected to the input of the block of reference phonograms, an autonomous power source, its output connected to the touch switch, the output of which is connected to the filter of the power circuit, which is connected to the mode switch for switching the low-noise amplifier with the inputs of the first, second, third and fourth band-pass filters.
Однако рассмотренный прототип имеет следующие существенные недостатки: However, the considered prototype has the following significant drawbacks:
- не является универсальным и постоянно действующим; - is not universal and permanent;
- не позволяет установить детальные параметры сигналов, а только их общие, интегральные характеристики, принимаемые на слух; - does not allow you to set the detailed parameters of the signals, but only their general, integral characteristics, taken by ear;
- не позволяет точно установить место в организме, из которого исходит акустический сигнал. - does not allow you to accurately determine the place in the body from which the acoustic signal comes.
Задачи изобретения решены и недостатки прототипа устранены в реализованном согласно настоящему изобретению способе акустического анализа состояния организма, заключающегося в том, что принимают акустические сигналы от акустической микрофонной решетки в течение длительного времени закрепленной на теле и состоящей из рядов микрофонов по несколько микрофонов в ряду и содержащей по меньше мере два ряда микрофонов и по меньше мере два микрофона в ряду, устанавливают свойства принятых от всех микрофонов сигналов, включая, но не ограничиваясь амплитудой, фазой и частотой сигнала, доплеровским сдвигом и расположением источника сигналов, включая место отражения звуковых волн, в том числе от внутренних органов, тканей и сосудов организма, после чего принятые сигналы сохраняют, выбирают диапазон свойств сигналов, который считают нормальным и сигнализируют об отклонения параметров от нормального с указанием
источника звукового сигнала, для которого установлено отклонение от нормального. The objectives of the invention are solved and the disadvantages of the prototype are eliminated in the method of acoustic analysis of the state of the body implemented according to the present invention, which consists in receiving acoustic signals from an acoustic microphone array for a long time fixed on the body and consisting of rows of microphones, several microphones in a row and containing at least two rows of microphones and at least two microphones in a row, set the properties of the signals received from all microphones, including, but not limited to, signal amplitude, phase and frequency, Doppler shift, and the location of the signal source, including the location of the reflection of sound waves, including from the internal organs, tissues and vessels of the body, after which the received signals are stored, the range of signal properties is selected, which is considered normal, and a deviation of the parameters from the normal is signaled, indicating audio source for which deviation from normal is set.
Медицински целесообразно основной акцент сделать на приеме акустических сигналы от сердца и лёгких. It is medically advisable to focus on receiving acoustic signals from the heart and lungs.
Технически и медицински целесообразно принятые сигналы накапливать во внешних системах It is technically and medically expedient to accumulate the received signals in external systems
Не менее целесообразно информацию при отклонении сигналов от нормальных оперативно передавать врачам. It is no less expedient to promptly transfer information to doctors in case of deviation of signals from normal ones.
За счет реализации заявленного авторами способа достигаются следующие технические результаты: By implementing the method claimed by the authors, the following technical results are achieved:
- мониторинг является универсальным и постоянно действующим; - monitoring is universal and permanent;
- позволяет установить детальные параметры сигналов; - allows you to set the detailed parameters of the signals;
- позволяет за счет разницы фаз на акустической решетке точно установить место, из которого исходит сигнал; - allows, due to the phase difference on the acoustic grating, to accurately determine the place from which the signal comes;
Настоящее изобретение будет раскрыто в нижеследующем описании пояса для определения состояния организма матери и плода во время течения беременности, содержащего решетку из трех рядов микрофонов по семь микрофонов в ряду. При этом принимают акустические сигналы от акустической микрофонной решетки в течение длительного времени закрепленной на теле беременной, устанавливают свойства принятых от всех микрофонов сигналов, в первую очередь, принимая сигналы от сердца матери и плода и устанавливая расположение источника сигналов, включая место отражения звуковых волн, в том числе от внутренних органов, тканей и сосудов организма матери и плода. The present invention will be disclosed in the following description of a belt for determining the state of the body of the mother and fetus during pregnancy, containing an array of three rows of microphones with seven microphones in a row. At the same time, acoustic signals are received from an acoustic microphone array fixed on the body of a pregnant woman for a long time, the properties of the signals received from all microphones are established, first of all, receiving signals from the heart of the mother and fetus and establishing the location of the signal source, including the place where sound waves are reflected, in including from the internal organs, tissues and vessels of the body of the mother and fetus.
После чего принятые сигналы сохраняют, выбирают диапазон свойств сигналов, который считают нормальным и сигнализируют об отклонения параметров от нормального с указанием источника звукового сигнала, для которого установлено отклонение от нормального. В первую очередь это пропадание пульса плода, пережатие пуповины, аритмия и тахикардия сердца матери. After that, the received signals are stored, a range of signal properties is selected, which is considered normal, and a deviation of the parameters from the normal is signaled, indicating the source of the sound signal for which the deviation from the normal is set. First of all, this is the loss of the fetal pulse, clamping of the umbilical cord, arrhythmia and tachycardia of the mother's heart.
При этом по месту расположения сердца плода возможно определить его прилежание (головкой вверх, вниз или горизонтально).
По сравнению со способами известными авторам, заявляемый способ обладает высокой универсальностью, постоянством и гибкостью, в отличие от ультразвука безвреден, позволяет достичь лучших результатов, является универсальным для различных типов заболеваний, не зависит от движения, позволяет быстро установить появление патологий и дефектов организма, позволяет классифицировать процессы наступления критических событий в организме по интенсивности и характеру сигналов, включая состояние беременности.
At the same time, according to the location of the fetal heart, it is possible to determine its diligence (head up, down or horizontally). Compared with the methods known to the authors, the claimed method has high versatility, constancy and flexibility, unlike ultrasound, it is harmless, allows you to achieve better results, is universal for various types of diseases, does not depend on movement, allows you to quickly identify the appearance of pathologies and defects in the body, allows to classify the processes of the onset of critical events in the body according to the intensity and nature of the signals, including the state of pregnancy.
Claims
ФОРМУЛА ИЗОБРЕТЕНИЯ CLAIM
Способ акустического анализа состояния организма, заключающий в том, что принимают акустические сигналы от акустической микрофонной решетки в течение длительного времени закрепленной на теле и состоящей из рядов микрофонов по несколько микрофонов в ряду и содержащей по меньше мере два ряда микрофонов и по меньше мере два микрофона в ряду, устанавливают свойства принятых от всех микрофонов сигналов, включая, но не ограничиваясь амплитудой, фазой и частотой сигнала, доплеровским сдвигом и расположением источника сигналов, включая место отражения звуковых волн, в том числе от внутренних органов, тканей и сосудов организма, после чего принятые сигналы сохраняют, выбирают диапазон свойств сигналов, который считают нормальным и сигнализируют об отклонении параметров от нормального с указанием источника звукового сигнала, для которого установлено отклонение от нормального. A method for acoustic analysis of the state of the body, which consists in receiving acoustic signals from an acoustic microphone array fixed on the body for a long time and consisting of rows of microphones with several microphones in a row and containing at least two rows of microphones and at least two microphones in a row. row, set the properties of the signals received from all microphones, including, but not limited to, the amplitude, phase and frequency of the signal, the Doppler shift and the location of the signal source, including the place of reflection of sound waves, including from the internal organs, tissues and blood vessels of the body, after which the received signals are stored, a range of signal properties is selected, which is considered normal, and a deviation of the parameters from normal is signaled, indicating the source of the sound signal for which the deviation from normal is set.
Способ по п.1, отличающийся тем, что в первую очередь принимают акустические сигналы от сердца и лёгких. The method according to claim 1, characterized in that, first of all, they receive acoustic signals from the heart and lungs.
Способ по п.1, отличающийся тем, что принятые сигналы накапливают во внешних системах The method according to claim 1, characterized in that the received signals are accumulated in external systems
Способ по п.1, отличающийся тем, что информацию при отклонении сигналов от нормальных оперативно передают врачам. The method according to claim 1, characterized in that information is promptly transmitted to doctors when the signals deviate from normal.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2192777C2 (en) * | 2000-04-07 | 2002-11-20 | Константинов Константин Викторович | Method for carrying out bioacoustic correction of psychophysiological organism state |
| RU2196500C2 (en) * | 1999-03-01 | 2003-01-20 | Институт коллоидной химии и химии воды им. А.В.Думанского НАН Украины | Diagnosis method and method for preparing fluid preparation for diagnosing human organism state |
| RU2234241C2 (en) * | 2002-09-11 | 2004-08-20 | Гольцов Владимир Викторович | Method and device for processing pulse wave signals, method for measuring pulse wave and method for processing parameter-measuring signals reflecting condition of organism organs and/or systems |
| RU2301091C2 (en) * | 2004-12-01 | 2007-06-20 | Общество с ограниченной ответственностью "Научно-медицинское предприятие "СВЯТОГОР" | Method for adjusting changed physiological human organism states |
| RU2729713C1 (en) * | 2019-12-16 | 2020-08-11 | Общество с ограниченной ответственностью (ООО) "АЛЬТОНИКА" | Measuring terminal for remote monitoring of railway transport workers |
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2021
- 2021-10-19 WO PCT/RU2021/000444 patent/WO2023068955A1/en active Application Filing
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| RU2196500C2 (en) * | 1999-03-01 | 2003-01-20 | Институт коллоидной химии и химии воды им. А.В.Думанского НАН Украины | Diagnosis method and method for preparing fluid preparation for diagnosing human organism state |
| RU2192777C2 (en) * | 2000-04-07 | 2002-11-20 | Константинов Константин Викторович | Method for carrying out bioacoustic correction of psychophysiological organism state |
| RU2234241C2 (en) * | 2002-09-11 | 2004-08-20 | Гольцов Владимир Викторович | Method and device for processing pulse wave signals, method for measuring pulse wave and method for processing parameter-measuring signals reflecting condition of organism organs and/or systems |
| RU2301091C2 (en) * | 2004-12-01 | 2007-06-20 | Общество с ограниченной ответственностью "Научно-медицинское предприятие "СВЯТОГОР" | Method for adjusting changed physiological human organism states |
| RU2729713C1 (en) * | 2019-12-16 | 2020-08-11 | Общество с ограниченной ответственностью (ООО) "АЛЬТОНИКА" | Measuring terminal for remote monitoring of railway transport workers |
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