WO2023061148A1

WO2023061148A1 - Implant conveying device

Info

Publication number: WO2023061148A1
Application number: PCT/CN2022/119267
Authority: WO
Inventors: 张平海; 徐佳; 李光辉; 陶霖; 陈国明; 吴旭闻; 毛婷
Original assignee: 上海微创心通医疗科技有限公司
Priority date: 2021-10-12
Filing date: 2022-09-16
Publication date: 2023-04-20

Abstract

An implant conveying device, comprising a conveying pipe assembly (10) and at least one control-by-wire assembly (20). The control-by-wire assembly (20) comprises: a wire fixing component (21) and a wire release component (22), wherein the wire fixing component (21) is configured to be connected to a fixing end (022a) of a pull wire in a pull wire group (02); the wire release component (22) is movably arranged in an axial direction of the conveying pipe assembly (10), and the wire release component (22) is configured to be connected to a release end (022b) of the pull wire in the pull wire group (02); and when the wire release component (22) satisfies a preset condition, the wire release component (22) is separated from the release end (022b) of the pull wire. In this way, when the preset condition is satisfied, the wire release component (22) is separated from the release end (022b) of the pull wire, such that even if the release end (022b) of the pull wire forms a free end, the pull wire group (02) can be separated from a support (01). The release action of the pull wire group is simple, there are fewer friction strokes, and the effect on the stability of the support in a wire withdrawal process is small, such that the rate of a successful operation is increased, and the problems of an existing conveyor having a long wire withdrawal path and complex operation are solved.

Description

Implant delivery device

technical field

The invention relates to the technical field of medical devices, in particular to an implant delivery device.

Background technique

Interventional valve prosthesis implantation is a new minimally invasive valve replacement technology developed internationally in recent years. Its principle is that the valve prosthesis is loaded into the delivery system and delivered to the implantation site through a catheter. At the root of the artery, the valve prosthesis is fixed to the aortic annulus after release, replacing the degraded original valve and improving the heart function of the patient. This technology can treat heart valve diseases without thoracotomy and heart beating, eliminating the huge trauma caused by previous surgical thoracotomy and cardiac arrest.

At present, there are mainly two mechanisms for valve prosthesis implantation: self-expanding and ball-expanding, each of which has advantages and disadvantages. Among them, the ball-expanding valve prosthesis can provide stable support and stability during release, but due to its The reason for the stent material is that it cannot be recovered after release; the advantage of the self-expanding valve prosthesis is that it can be corrected, and it can be recovered and released again during the implantation process, but due to the nature of the self-expanding stent, it cannot During release, the morphology is not conducive to anchoring.

At present, there is a wire-controlled technology based on self-expanding valve prosthesis. The purpose of wire-control is to increase wire-control on the basis of self-expanding valve prosthesis, so as to realize a release mechanism similar to ball expansion, and improve the implantation process. stability, thereby improving the success rate of surgery.

In the wire-controlled technology, there are two factors that directly affect the success rate of the operation: one is thread withdrawal, that is, the conveyor withdraws the pull wire from the stent. Because of the friction between the wire and the bracket during the withdrawal process, the wire always exerts a force on the bracket, and this force is likely to cause the bracket to shift, resulting in failure of the operation; It is necessary to provide a break point, which is the prerequisite for thread withdrawal. The mechanism of thread breakage will affect the structure of the conveyor, increase the complexity of the operation, and affect the success rate of the operation.

In the prior art, there are problems such as long thread withdrawal path and complicated operation, resulting in poor stability of valve prosthesis and high difficulty of operation.

Contents of the invention

The object of the present invention is to provide an implant delivery device to solve the problems of long wire withdrawal path and complicated operation of the existing conveyor.

In order to solve the above technical problems, the present invention provides an implant delivery device, which includes: a delivery tube assembly and at least one wire control assembly; the wire control assembly includes: a wire fixing part and a wire detachment part;

The wire fixing part is used to connect with the fixed end of the stay wire in the stay wire set;

The wire detachment part is movably arranged along the axial direction of the delivery tube assembly, and the wire detachment part is used to connect with the detachment end of the pull wire in the pull wire group; when the wire detachment part satisfies the preset condition , the wire disengagement part is disengaged from the disengagement end of the pull wire.

Optionally, the wire fixing component is movably arranged along the axial direction of the delivery tube assembly.

Optionally, the wire detachment part is located at the proximal end of the wire fixing part, and when the wire detachment part does not meet the preset condition, the wire detachment part and the wire fixing part synchronously move along the delivery tube assembly axial movement.

Optionally, the delivery tube assembly includes an inner tube, and the wire fixing component is movably sleeved outside the inner tube.

Optionally, the preset condition includes mechanical movement of the wire breaking away component.

Optionally, the wire detachment part includes a pin-shaped part, the pin-shaped part has an opening, and the pin-shaped part is used for connecting the detachment end of the pull wire; the preset condition includes: the wire detachment part moving relative to the disengagement end of the pull wire, so that the disengagement end of the pull wire disengages from the opening.

Optionally, the delivery device further includes a traction member, the first end of the traction member is connected to the pin-shaped member, and the second end of the traction member extends proximally.

Optionally, when the disengagement end of the pull wire is connected to the wire disengagement part, the wire disengagement part is in a connected state, and the axial distance between the wire control assembly and the distal end of the delivery device is not greater than 300mm.

Optionally, the wire fixing part includes a driving part, and the driving part is movably arranged along the axial direction of the delivery tube assembly; the driving part has a first limiting structure, and the first limiting structure uses to limit the circumferential position of the pull wire around the delivery tube assembly.

Optionally, the first limiting structure includes a plurality of first through holes opened along the axial direction of the driving member, or, the first limiting structure includes a plurality of holes along the axial direction of the driving member. A first groove opened on the outer periphery of the driving member; the first through hole or the first groove is used for passing the pull wire.

Optionally, the wire fixing part further includes a fixing structure, and the fixing structure is used for connecting with the fixing end of the pull wire.

Optionally, the two different first through holes are used for the same pull wire to pass through and wind in turn, and the driving member and the two different first through holes thereon are jointly configured as the the fixed structure.

Optionally, the fixing structure includes: a first fixing ring, the first fixing ring is used for wrapping around the fixing end of the pull wire;

The radially inner dimension of the first fixing ring is smaller than the radially outer dimension of the driving member, and the first fixing ring is used to abut against the driving member; or

The first fixing ring is fixedly sleeved on the outer periphery of the driving member.

Optionally, the wire control assembly further includes: a wire deployment component; the delivery tube assembly includes an inner tube;

The wire deploying part is fixedly connected with the inner tube; the wire deploying part is used for changing the extending direction of the pulling wire to along the radial direction of the delivery tube assembly after the pulling wire converges on it Axial extension of the delivery tube assembly described above.

Optionally, the wire deployment part includes a transition piece, the transition piece has a second limiting structure, and the second limiting structure is used to limit the circumferential position of the pull wire around the delivery tube assembly.

Optionally, the second limiting structure includes a plurality of second through holes opened along the axial direction of the conversion member; or, the second limiting structure includes a plurality of holes along the axial direction of the conversion member. A second groove is provided on the outer periphery of the conversion member; the second through hole or the second groove is used for passing the pull wire.

Optionally, the wire deployment part further includes a transition structure, and the transition structure is used to gradually change the extension direction of the pull wire.

Optionally, the transition structure includes: a second fixing ring;

The second fixing ring is fixedly arranged relative to the conversion element, and the second fixing ring is used for winding the pull wire to change the extending direction.

Optionally, the transition piece has a hole opened along the axial direction of the delivery tube assembly, and the second limiting structure includes a plurality of third holes opened along the radial direction of the transition piece and communicated with the hole. The through hole; the transition structure includes the third through hole; the tunnel and the third through hole are used for passing the pull wire to change the extending direction.

Optionally, the delivery device of the implant includes more than two wire control assemblies, and the wire fixing parts of the wire control assemblies of the two or more wire control assemblies are used to connect with the pull wire group along the delivery tube. The components are offset radially and/or circumferentially from one another.

Optionally, the wire fixing parts of more than two wire control assemblies are fixed to each other; or, the wire fixing parts of more than two wire control assemblies are mutually independent along the axial direction of the delivery tube assembly of the mobile.

Optionally, the stay wire set includes a plurality of stay wires, and the wire fixing component is used for converging and connecting fixed ends of the plurality of stay wires.

Optionally, the conveying device further includes at least one pull wire set, and the pull wire set includes at least one pull wire.

In summary, the implant delivery device provided by the present invention includes: a delivery tube assembly and at least one wire control assembly; the wire control assembly includes: a wire fixing part and a wire detachment part; the wire fixing part is used for The fixed ends of the stay wires in the stay wire group are connected; the wire disengagement part is movably arranged along the axial direction of the delivery tube assembly, and the wire disengagement part is used to connect with the disengagement ends of the stay wires in the stay wire group; When the wire disengagement part satisfies a preset condition, the wire disengagement part is disengaged from the disengagement end of the pull wire.

In such a configuration, the wire fixing part is connected to the fixed end of the pull wire, and the wire detachment part is connected to the detachment end of the pull wire. , so that the pull wire group can be separated from the bracket. The detachment action of the pull wire group is simple, the friction stroke is small, the stability of the bracket is less affected during the wire withdrawal process, the success rate of the operation is improved, and the problems of long wire withdrawal path and complicated operation of the existing conveyor are overcome.

Description of drawings

Those of ordinary skill in the art will understand that the provided drawings are for better understanding of the present invention, but do not constitute any limitation to the scope of the present invention. in:

FIG. 1 is a schematic diagram of an example of a wire-controlled valve prosthesis according to an embodiment of the present invention;

2 is a schematic diagram of another example of a wire-controlled valve prosthesis according to an embodiment of the present invention;

Fig. 3 is a schematic diagram of the assembly of the implant delivery device and the wire-controlled valve prosthesis according to the embodiment of the present invention;

4 is a schematic diagram of an implant delivery device according to an embodiment of the present invention;

5 is a schematic diagram of a delivery tube assembly according to an embodiment of the present invention;

Figures 6a to 6c are schematic diagrams of several preferred examples of the pin-shaped member of the embodiment of the present invention;

Figures 7a to 7c are schematic diagrams of several preferred examples of wire fixing components according to embodiments of the present invention;

8a to 8d are schematic diagrams of several preferred examples of the first through hole and the second through hole according to the embodiment of the present invention;

Fig. 9a and Fig. 9b are schematic diagrams of several preferred examples of wire deployment components according to the embodiment of the present invention;

Fig. 10 is a schematic diagram of assembly of a dismantling line and a conveying device according to an embodiment of the present invention;

Fig. 11 is an enlarged view of part A of Fig. 10;

Fig. 12 is a schematic diagram of a preferred example of two wire control assemblies of the delivery device according to the embodiment of the present invention;

Fig. 13 is an enlarged view of part B of Fig. 12;

Fig. 14 is a schematic diagram of another preferred example of two wire control assemblies of the delivery device according to the embodiment of the present invention;

Fig. 15 is an enlarged view of part C of Fig. 14;

Fig. 16 is a schematic structural view of the inner tube mechanism of the delivery device according to an embodiment of the present invention; Fig. 17 is a schematic structural view of the wire deployment part of the delivery device according to an embodiment of the present invention;

Fig. 18 is an A-A sectional view of the wire deployment part of the delivery system according to an embodiment of the present invention;

Fig. 19 is a schematic diagram of the connection relationship between the pull wire and the medical implant when the delivery system according to an embodiment of the present invention is loaded with the medical implant. In the illustration, the pull wire is connected to the medical implant in the form of radiation;

Fig. 20 is a schematic diagram of the connection relationship between the pull wire and the medical implant when the delivery device according to an embodiment of the present invention is loaded with the medical implant. In the illustration, the pull wire surrounds the medical implant in the circumferential direction;

Fig. 21 is a schematic structural view of the wire deployment part of the delivery device according to another embodiment of the present invention, the wire deployment part in the illustration does not include a base;

Fig. 22 is a schematic structural view of the wire deploying part of the delivery device according to another embodiment of the present invention, the wire deploying part in the illustration includes a base;

Fig. 23 is a schematic structural view of the line deployment part of the delivery system according to another embodiment of the present invention, and the viewing directions of Fig. 23 and Fig. 22 are different;

Fig. 24 is a schematic diagram of deflection of the extension direction of the pull wire of the delivery system according to another embodiment of the present invention when passing through the hole on the wire deployment component;

Fig. 25 is a schematic diagram of a partial structure of a medical device according to an embodiment of the present invention. In the figure, the medical implant is in a crimped state, and the medical device includes a wire deploying part, which is arranged on the medical implant. distal side;

Fig. 26 is a schematic diagram of the expansion of the medical stent in the medical device shown in Fig. 25;

Fig. 27 is a schematic diagram of a partial structure of a medical device according to an embodiment of the invention. In the figure, the medical implant is in a crimped state, and the medical device includes two wire deployment parts, which are respectively arranged on the medical implant. the proximal and distal sides of the object;

Fig. 28 is a schematic diagram of a partial structure of a medical device according to an embodiment of the present invention. In the figure, the medical device is in a crimped state, and the medical device includes a wire deploying part, and a wire deploying part is arranged inside the medical implant. And the angle formed by the part of the pull wire between the wire deployment part and the medical implant and the axis of the delivery system is 90°;

Fig. 29 is a schematic diagram of a partial structure of a medical device according to an embodiment of the present invention. In the figure, the medical device is in a crimped state, and the medical device includes a wire deploying part, and a wire deploying part is arranged inside the medical implant, and The angle formed by the portion of the pull wire between the wire deployment member and the medical implant and the axis of the delivery system is less than 90°.

In the attached picture:

01-bracket; 02-pull wire group; 021-fixed wire; 022-detachment wire; 022a-fixed end; 022b-detachment end;

10-transport tube assembly; 11-inner tube; 12-outer tube; 13-sheath tube; 14-tapered head; 20-wire control component; ; 211b-the first groove; 212-guy wire tube; The second through hole; 231b-the second groove; 232-the second fixing ring; 233-the channel; 234-the third through hole.

1000-inner tube mechanism, 1100-inner tube, 1200-wire deployment part, 1200a-proximal segment, 1200b-second segment, 1210-threading channel, 1201-guiding surface, 1201a-first sub-guiding surface, 1201b - second sub-guiding surface, 1201c - third sub-guiding surface, 1211 - first hole section, 1212 - second hole section, 1213 - third hole section, 1220 - installation through hole, 1230 - line deployment component body, 1231 -threading slot, 1240-rotating member, 1241-positioning slot, 1250-base, 1251-introduction channel, 2000-outer tube, 200-handle, 20-guy wire, 2-medical implant.

Detailed ways

In order to make the purpose, advantages and features of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments. It should be noted that the drawings are all in very simplified form and not drawn to scale, and are only used to facilitate and clearly assist the purpose of illustrating the embodiments of the present invention. In addition, the structures shown in the drawings are often a part of the actual structure. In particular, each drawing needs to display different emphases, and sometimes uses different scales.

As used in the present invention, the singular forms "a", "an" and "the" include plural objects, the term "or" is usually used in the sense of including "and/or", and the term "several" Usually, the term "at least one" is used in the meaning of "at least one", and the term "at least two" is usually used in the meaning of "two or more". In addition, the terms "first", "second "Two" and "third" are used for descriptive purposes only, and should not be understood as indicating or implying relative importance or implicitly indicating the quantity of the indicated technical features. Thus, a feature defined as "first", "second", and "third" may explicitly or implicitly include one or at least two of these features, the term "proximal end" is usually the end close to the operator, the term The "distal end" is usually the end close to the patient, that is, the end close to the lesion. "One end" and "the other end" as well as "proximal end" and "distal end" usually refer to the corresponding two parts, which not only include the end point, the term "installation" , "connected" and "connected" should be understood in a broad sense. For example, it can be fixed connection, detachable connection, or integrated; it can be mechanical connection or electrical connection; it can be direct connection or through The intermediary is indirectly connected, which can be the internal communication of two elements or the interaction relationship between two elements. In addition, as used in the present invention, an element is arranged on another element, usually only means that there is a connection, coupling, cooperation or transmission relationship between the two elements, and the relationship between the two elements can be direct or indirect through an intermediate element. connection, coupling, fit or transmission, but should not be understood as indicating or implying the spatial positional relationship between two elements, that is, one element can be in any orientation such as inside, outside, above, below or on one side of another element, unless the content Also clearly point out. Those of ordinary skill in the art can understand the specific meanings of the above terms in the present invention according to specific situations.

Description is made below with reference to the accompanying drawings.

Please refer to Fig. 1 to Fig. 15, wherein, Fig. 1 is the schematic diagram of an example of the wire-controlled valve prosthesis of the embodiment of the present invention; Fig. 2 is the schematic diagram of another example of the wire-controlled valve prosthesis of the embodiment of the present invention; Fig. 3 is a schematic diagram of the implant delivery device of the embodiment of the present invention assembled with the wire-controlled valve prosthesis; FIG. 4 is a schematic diagram of the implant delivery device of the embodiment of the present invention; FIG. 5 is a delivery device of the embodiment of the present invention A schematic diagram of a pipe assembly; Figures 6a to 6c are schematic diagrams of several preferred examples of pin-shaped parts in embodiments of the present invention; Figures 7a to 7c are schematic diagrams of several preferred examples of wire fixing components in embodiments of the present invention; Figures 8a to Fig. 8d is a schematic diagram of several preferred examples of the first through hole and the second through hole of the embodiment of the present invention; Fig. 9a and Fig. 9b are schematic diagrams of several preferred examples of the wire deployment part of the embodiment of the present invention; Figure 11 is an enlarged view of part A of Figure 10; Figure 12 is a schematic diagram of a preferred example of two wire control components of the delivery device according to the embodiment of the present invention; Figure 13 is a diagram 12 is an enlarged view of part B; FIG. 14 is a schematic diagram of another preferred example of two wire control assemblies of the delivery device according to an embodiment of the present invention; FIG. 15 is an enlarged view of part C of FIG. 14 .

Figure 1 and Figure 2 show an implant, specifically a wire-controlled valve prosthesis, which includes: a stent 01 and at least one puller group 02, the stent 01 is preferably a self-expandable stent, which can expand radially or shrink. A part of the pull wire group 02 is arranged around the stent 01 in a circumferential direction, and the expansion or contraction of the stent 01 can be controlled by driving the pull wire group 02 . A pull wire group 02 includes at least one pull wire. In some embodiments, the pull wire can be divided into at least one fixing wire 021 and at least one detachment wire 022 according to different functions. The fixed wire 021 can be understood as a pull wire with fixed ends 022a at both ends, and both fixed ends 022a are connected to the wire fixing part 21 of the conveying device, thereby forming a loop. If there are more than two fixed wires 021, the latter fixed wire 021 passes through the ring of the previous fixed wire 021 to form a relationship of pin connection in turn; 022a is used to connect with the wire fixing part 21 of the delivery device, and the disengagement end 022b is used to be connected with the wire release part 22 of the delivery device. Then dismantling line 022 passes through the loop of the last fixed line 021, and pins the last fixed line 021. In such a configuration, after the disengagement part 22 and the disengagement end 022b are disengaged, the detachment wire 022 is equivalent to releasing the pinning of the last fixing wire 021, and several fixing wires 021 are also releasing the pinning relationship in turn, so that the entire pull wire group 02 and the bracket 01 break away from each other to complete the line withdrawal. In the example shown in FIG. 1 , the detachment line 022 forms a single coil loop. As shown in FIG. 2, in some other embodiments, the detachment line 022 forms a double coil loop. In some other embodiments, the pull wires are all used for detachment without distinguishing between the fixed wire and the detachment wire, or all the pull wires can be considered as the detachment wire 022 . In these embodiments, each pull wire has a fixed end 022a connected to the wire fixing member 21 of the delivery device and a disengaged end 022b connected to the wire release member 22 of the delivery device. With such configuration, after the wire disengagement part 22 is disengaged from the disengagement end 022b of the wire, the disengagement end 022b of the wire is released, so that the wire group 02 and the bracket 01 are disengaged from each other to complete wire withdrawal.

Based on the above-mentioned wire-controlled valve prosthesis, the pull wires can be extended to the proximal end for manipulation, which makes it easy for the pull wires to form crossing and entanglement with each other and affect the operation. Therefore, referring to FIG. 3 , FIG. 4 and FIG. 5 , an embodiment of the present invention provides an implant delivery device, which includes: a delivery tube assembly 10 and at least one wire control assembly 20; the wire control assembly 20 includes: The wire fixing part 21 and the wire breaking part 22; the wire fixing part 21 is used to connect with the fixed end 022a of the pull wire in the pull wire group 02; The axial direction of the tube 11, see the description of the inner tube 11 below for details), and the wire disengagement part 22 is used to connect with the disengagement end 022b of the pull wire in the pull wire group 02; when the wire disengagement part 22, when the preset condition is met, the wire disengagement component 22 is disengaged from the disengagement end 022b of the pull wire.

The wire disengagement part 22 disengages from the disengagement end 022b of the pull wire under preset conditions, and the preset conditions here may be different according to different structures of the wire disengagement part 22, for example, in some embodiments, the wire disengagement part 22 is a mechanical disengagement structure , then the preset condition can be that the wire detachment part 22 moves mechanically, such as the wire detachment part 22 mechanically moves, expands or unlocks, etc.; It may be energized; in some other embodiments, the wire detachment component 22 is a dissolving structure, and the preset condition may be waiting for a certain period of time and so on. Those skilled in the art can set specific preset conditions according to different structures of the wire breaking away part 22.

Please refer to FIG. 5, and in combination with FIG. 3 and FIG. 4, the delivery tube assembly 10 includes an inner tube 11, and the inside of the inner tube 11 can be used for passing a guide wire. The extension direction of the inner tube 11 is its axial direction, that is, the entire The axial direction of the delivery tube assembly 10 . It can be understood that since the inner tube 11 is bendable, its axial direction is not fixed as a straight line, but bends following the bending of the inner tube 11 . The proximal end of the inner tube 11 is connected to the handle 15 , and the wire fixing part 21 of the wire control assembly 20 is movably sleeved outside the inner tube 11 . Further, the delivery tube assembly 10 also includes an outer tube 12 and a sheath tube 13, the outer tube 12 is movably sleeved outside the wire control assembly 20, the sheath tube 13 is movably sleeved outside the outer tube 12, and the implant can be It is accommodated in the sheath tube 13 . Optionally, the distal end of the inner tube 11 is provided with a tapered head 14 to facilitate the passage of the delivery device. As for the specific structure of the delivery tube assembly 10, those skilled in the art can understand and configure it according to the prior art, which is not described in detail in the present invention.

In some embodiments, the wire fixing part 21 is movably arranged along the axial direction of the delivery tube assembly 10, the pull wire group 02 includes a plurality of pull wires, and the wire fixing part 21 is used for fixing a plurality of the pull wires. Terminal 022a is confluently connected. The wire fixing part 21 brings together the fixed ends 022a of multiple stay wires in the pull wire group 02 (it can be understood that if the pull wires include the fixing wires 021 and the dismounting wires 022, then the wire fixing part 21 collects the fixed ends of all the fixing wires 021 and the dismounting wires 022 022a), driving the wire fixing component 21 along the axial direction of the delivery tube assembly 10 can control the retraction and retraction of the pull wire group 02 . In some other embodiments, the wire fixing part 21 is fixedly arranged along the axial direction of the delivery tube assembly 10, for example, the wire fixing part 21 can be arranged at the handle at the proximal end, and the control is realized by directly driving the proximal end of the pull wire. The retraction and release of the pull wire group 02.

Preferably, when the detachment end 022b of the pull wire is connected to the wire detachment member 22, the wire detachment member 22 is in a connected state, and at this time the wire control assembly 20 is connected to the shaft at the distal end of the delivery device. The axial distance (should be understood as the axial distance between the proximal end of the wire control assembly 20 and the farthest end of the delivery device) is not greater than 300 mm. The wire fixing part 21 and the wire detaching part 22 are integrated in the distal part of the delivery tube assembly 10 close to each other, which simplifies the wire control structure of the delivery device. In addition, the retraction and detachment of the puller group 02 is simple, the friction stroke is less, and the stability of the bracket 01 is less affected during the withdrawal process, which improves the success rate of the operation and overcomes the problems of long withdrawal path and complicated operation of the existing conveyor .

Please refer to FIGS. 6a to 6c. In one example, the wire detachment member 22 is a mechanical detachment structure, which includes a pin-shaped member 221, and the pin-shaped member 221 has an opening; the preset condition includes: the The wire disengagement member 22 moves relative to the disengagement end 022b of the pull wire, so that the disengagement end 022b of the pull wire disengages from the opening. This embodiment does not limit the specific shape of the pin-shaped member 221. Figures 6a to 6c show spiral, L-shaped and hook-shaped pin-shaped members 221 respectively. Their common feature is that they have openings but not closures. When the shaped part 221 moves proximally relative to the disengagement end 022b, the pin-shaped part 221 can be deformed under force, so that the disengagement end 022b of the pull wire slips off from the pin-shaped part 221 . In an alternative example, the pin-shaped member 221 is in a spiral shape, and the number of turns of the spiral is between 1-3. The pin-shaped member 221 can be made of metal or non-metallic material, understandably, the force to deform the pin-shaped member 221 should be less than the tensile limit of the pull wire.

Preferably, the delivery device further includes a traction member 222, one end of the traction member 222 is connected to the pin-shaped member 221, and the other end of the traction member 222 extends proximally. The traction member 222 can be a traction wire or the like, which can be connected to the handle after extending proximally, and the operator can pull the traction member 222 through the handle at the proximal end, thereby moving the pin-shaped member 221 toward the proximal end. It should be noted that if the traction member 222 is a component such as a traction wire that can only be pulled but cannot transmit thrust, the pin-shaped member 221 can be configured to disengage from the pull wire when moving toward the proximal end. Of course, in some other embodiments, if the guide tube is used as the traction member 222, since it can transmit thrust, the moving direction of the pin-shaped member 221 and the pulling wire can be unrestricted. In order to reduce the size of the conveying device, it is preferable to use a pulling member such as a pulling wire as the pulling member 222 .

Further, the thread breaking part 22 is located at the proximal end of the thread fixing part 21, and when the thread breaking part 22 does not meet the preset condition, the thread breaking part 22 and the thread fixing part 21 synchronously move along the The axial movement of the delivery tube assembly 10 is described. When the preset condition is not met, all the pulling wires have substantially the same function, and they are all used to drive and control the contraction or expansion of the stent 01 . Therefore, the wire disengagement part 22 and the wire fixing part 21 should be configured to move synchronously along the axial direction of the delivery tube assembly 10, so that each pull wire is retracted synchronously.

Please refer to FIG. 7a to FIG. 7c, the wire fixing part 21 includes a driving member 211, and the driving member 211 is movably arranged along the axial direction of the delivery tube assembly 10; the driving member 211 has a first stop structure , the first limiting structure is used to limit the circumferential position of the pull wire around the delivery tube assembly 10 . Optionally, the delivery device also includes a pull-wire tube 212, the proximal end of the driver 211 is connected to the pull-wire tube 212, the pull-wire tube 212 extends to the proximal end and is connected to the handle, the operator can use the handle at the proximal end to Pull or push the pull wire tube 212 to the distal end, thereby driving the driving member 211 to move along the axial direction of the delivery tube assembly 10 . The driving part 211 can be arranged on the part near the distal end of the delivery tube assembly 10, and the driving part 211 can collect the pull wires of the converging pull wire group 02, thus, each pull wire of the pull wire group 02 is at the distal end of the entire delivery device, and the driving part 211 is controlled by the cable tube 212 , the wiring path of the cable group 02 is short, and each cable can be retracted synchronously, so that the release precision of the bracket 10 is high. Further, the setting of the first limiting structure can limit the circumferential position of each of the pull wires of the pull wire set 02, and avoid interlacing and entanglement among them.

Preferably, the first limiting structure includes a plurality of first through holes 211a (as shown in FIG. It includes a plurality of first grooves 211b (as shown in FIG. 7c ) opened on the outer periphery of the driving member 211 along the axial direction of the driving member 211; the first through hole 211a or the first groove 211b is used For the said stay wire to pass through. In the example shown in Fig. 7a and Fig. 7b, the driving member 211 is a multi-lumen tube, each of the first through holes 211a can accommodate one or more pull wires to pass through. Thus, the first through hole 211a limits the circumferential position of the pull wire. In this embodiment, the cross-sectional shape and quantity of the first through hole 211a and the first groove 211b are not limited, and Fig. 8a to Fig. 8d exemplarily show several preferred cross-sectional shapes of the first through hole 211a. It should be understood that Fig. 8a to Fig. 8d are only examples of the cross-sectional shape and quantity of the first through holes 211a rather than limiting the cross-sectional shape and quantity of the first through holes 211a. In the example shown in FIG. 7c, the driving member 211 is a gear-like structure with a plurality of first grooves 211b on its outer periphery, and each first through hole 211a can accommodate one or more pull wires to pass through. It is also possible to limit the circumferential position of the pull wire.

Further, the wire fixing part 21 also includes a fixing structure, and the fixing structure is used for connecting with the fixing end 022a of the pull wire. In the example shown in FIG. 7a, the different two first through holes 211a are used for the same pull wire to pass through and wind in sequence, and the driving member 211 and the different two first through holes thereon A through hole 211a is commonly configured as the fixing structure. Preferably, the same pull wire passes through two adjacent first through holes 211a in sequence, that is, the connection between the pull wire and the driving member 211 is completed. It can be understood that, in the exemplary example shown in FIG. 7a, the pull wire preferably forms a double-coil loop as shown in FIG. Two first through holes 211a.

In the example shown in FIG. 7b and FIG. 7c, the fixing structure includes: a first fixing ring 213, and the first fixing ring 213 is used for winding the fixing end 022a of the pull wire so that the pull wire and the wire The fixing part 21 forms the connection. It should be noted that the winding here may be a double wire winding, or a single wire itself forming a loop (such as forming by knotting or welding).

In some embodiments, the fixing structure includes a first fixing ring 213 additionally attached to the driving member 211. In the example shown in FIG. 7b, the radial inner dimension of the first fixing ring 213 is smaller than that of the driving member 211 , the first fixing ring 213 is used to abut against the driving member 211 . It should be noted that the radial inner dimension of the first fixing ring 213 refers to the smallest inner dimension of the first fixing ring 213 along the radial direction. Optionally, if the inner circumference of the first fixing ring 213 is circular, the radial inner dimension of the first fixing ring 213 is its inner diameter. If the inner periphery of the first fixing ring 213 is polygonal, the radial inner dimension of the first fixing ring 213 is the diameter of its inscribed circle. The same applies to the radial inner dimensions of the other components described below. The radial outer dimension of the driving member 211 refers to the maximum outer dimension of the driving member 211 along the radial direction. Optionally, if the outer circumference of the driving member 211 is circular, the radial outer dimension of the driving member 211 is its outer diameter. If the outer circumference of the driving member 211 is polygonal, the radial outer dimension of the driving member 211 is the diameter of its circumscribed circle. The same applies to the radial outer dimensions of the other components described below.

In an optional embodiment, the first fixing ring 213 is located at the proximal end of the driving member 211, and after the fixing end 022a of the pull wire is wound around the first fixing ring 213, it passes through the first through hole 211a toward the distal end. Extend, and then surround the bracket 01. When the driving member 211 is pulled toward the proximal end, the first fixing ring 213 is driven by the driving member 211 to move toward the proximal end together, so that the pull wire is pulled toward the proximal end. When the driving member 211 is pushed toward the distal end, the self-expanding of the stent 01 drives the pull wire to move toward the distal end, and drives the first fixing ring 213 to move toward the distal end and continue to abut against the driving member 211 . It should be understood that this embodiment does not limit the arrangement of the first fixing ring 213 at the proximal end of the driving member 211. In other embodiments, the relationship between the first fixing ring 213 and the driving member 211 may also be reversed, that is, the second A fixing ring 213 is arranged on the distal end of the driving member 211. At this time, when the driving member 211 is pushed toward the distal end, the stent 01 is driven to shrink for tightening the stay wire, and when the driving member 211 is pulled toward the proximal end, it is for loosening the stay wire. , the stent 01 is expanded.

In the example shown in FIG. 7 c , the first fixing ring 213 is fixedly sleeved on the outer periphery of the driving member 211 . Preferably, the first limiting structure of the driving member 211 includes a plurality of first grooves 211b formed on the outer periphery of the driving member 211 along the axial direction of the driving member 211 . The first fixing ring 213 and the driving member 211 can be connected by means of welding, bonding, mechanical limit, etc., and the inner circumference of the first fixing ring 213 and the first groove 211b form a closed hole, which can be used for fixing the pull wire The terminal 022a is wound around, and its principle is similar to the example shown in FIG. 7b , which will not be repeated here.

Preferably, the wire control assembly 20 further includes: a wire deployment part 23; the wire deployment part 23 is fixedly connected with the inner tube 11; After the radial direction of 10 merges with it, the extension direction of the pull wire is changed to extend along the axial direction of the delivery tube assembly 10 . The wire deployment part 23 is mainly used to change the extension direction of the pull wire. Preferably, the axial position of the wire deployment part 23 along the delivery tube assembly 10 is adapted to the loading position of the stent 01, more preferably, the distal end of the wire deployment part 23 is adapted to the position where the pull wire wraps around the stent 01, so as to Minimize the angle of the stay wires between the wire deployment part 23 and the bracket 01 relative to the radial direction of the bracket 01 as far as possible, and preferably make this part of the stay wires parallel to the radial direction of the bracket 01 .

Optionally, the wire deployment part 23 includes a conversion piece 231, and the conversion piece 231 has a second limiting structure, and the second limiting structure is used to limit the circumferential direction of the pull wire around the delivery tube assembly 10. Location. The arrangement of the second limiting structure can limit the circumferential position of each of the pull wires of the pull wire set 02 to avoid interlacing and entanglement among them.

Preferably, the second limiting structure includes a plurality of second through holes 231a penetrating through the axial direction of the conversion member 231; or, the second limiting structure includes a plurality of holes 231a along the conversion member 231 The second groove 231b axially opened on the outer periphery of the conversion member 231; the second through hole 231a or the second groove 231b is used for passing the pull wire. The structure and setting principle of the second through hole 231a and the second groove 231b are similar to the first through hole 211a and the first groove 211b on the driving member 211. In this embodiment, the second through hole 231a and the second groove 231b The cross-sectional shape of is not limited, and the second through hole 231a may be as shown in FIG. 8a to FIG. 8d.

Preferably, the wire deploying part 23 further includes a transition structure, and the transition structure is used to gradually change the extension direction of the pull wire. It should be noted that gradually changing the extension direction of the stay wire here means that the stay wire has a certain turning radius at the transition structure, rather than a sharp corner. Optionally, the gradual change may be, for example, a smooth change in the shape of an arc, or a multi-fold change formed by multiple fold lines. The arrangement of the transition structure can effectively reduce the abrasion of the stay wire.

Please refer to FIG. 9a, in an alternative example, the transition structure includes: a second fixing ring 232; It is used for changing the extending direction of the pulling wires. In the example shown in Fig. 9a, the outer circumference of the conversion member 231 has a second groove 231b opened in the axial direction, and the second fixing ring 232 and the conversion member 231 can be connected by means of welding, bonding, mechanical limit, etc. The inner circumference of the two fixing rings 232 and the second groove 231b form a closed hole, which can be used for the fixed end 022a of the backguy to wrap around to change the extension direction, which not only limits the circumferential position of the backguy, but also the second fixing ring 232. As a transitional structure, the pull wire can smoothly change the direction of extension. Of course, in other embodiments, the conversion member 231 having the second through hole 231a may also be used to cooperate with the second fixing ring 232 to change the extension direction of the pull wire, and the present invention is not limited thereto.

Please refer to FIG. 9b. In another alternative example, the conversion member 231 has a hole 233 opened along the axial direction of the delivery tube assembly 10, and the second limiting structure includes a plurality of The third through hole 234 opened radially of the member 231 and communicated with the hole 233; the transition structure includes the third through hole 234; the hole 233 and the third through hole 234 are used for the The extension direction is changed by passing the pull wire. The hole 233 can be in various forms such as a through hole, a blind hole or a ring groove, and the pull wire can pass through the hole 233 and then pass through the third through hole 234 to change the extending direction. In the example shown in FIG. 9 b , the hole 233 is annular and opens towards the proximal end along the axial direction of the conversion member 231 , and the side wall of the third through hole 234 serves as a transition structure. Preferably, the intersection of the side wall of the third through hole 234 and the channel 233 is an arc surface to form a smooth transition. With such a configuration, the outer circumference of the conversion piece 231 can no longer be provided with an additional second fixing ring 232, which reduces the radial outer dimension of the wire deployment part 23, reduces the contact height between the wire deployment part 23 and the implant, and reduces the impact on the implant. Interference during implant crimping.

Please refer to FIG. 16 , in another alternative example, the wire deploying part 1200 is disposed on the outer surface of the distal end of the inner tube 1100, and when the number of the wire deploying parts 1200 is more than two, More than two wire deployment parts 1200 are disposed on the inner tube 1100 at intervals in the axial direction. A threading channel 1210 is formed on the thread deployment part 1200, and a part of the surface of the threading channel 1210 is formed as a smooth guide surface 1201, and the guide surface 1201 is used to guide the threading channel 1210 when the pull wire 20 passes through the threading channel 1210. The pull wire 20 provides support force and deflects the extending direction of the pull wire 20 . Here, "smooth" means that there are no sharp edges on the guide surface 1201, that is, the guide surface 1201 is a continuous curved surface, or the guide surface 1201 includes a plurality of different surfaces, mostly A different surface can be a plane or a curved surface, and multiple different surfaces are connected with a smooth transition.

The optional structure of the line deploying part 1200 will be described in detail below.

In one embodiment of the present invention, as shown in Figure 17 and Figure 18, the guide surface 1201 includes a first sub-guiding surface 1201a, a second sub-guiding surface 1201b, and a first Three sub-guiding surfaces 1201c. Wherein, the axes of the first sub-guiding surface 1201a and the third sub-guiding surface 1201c are both straight lines, and the angle formed between them is 45°-135°. The axis of the second sub-guiding surface 1201b is an arc, so that on a section parallel to the axial direction of the wire deployment component 1200, at least a part of the outline of the second sub-guiding surface 1201 is a curve. In this way, when the distal end of the pull wire 20 passes through the threading channel 1210, under the support of the guide surface 1201, the pull wire 20 is at the exit of the threading channel 1210 (ie, the third sub-guiding The extension direction of the surface 1201c away from the end of the second sub-guiding surface 1201b) relative to the extension direction of the pull wire 20 at the entrance of the threading channel 1210, the deflection angle can be at least 45°～ Choose from a range of 135°.

Optionally, an installation through hole 1220 is formed on the wire deployment part 1200 , and the wire deployment part 1200 is installed on the inner tube 1100 through the installation through hole 1220 . The threading channel 1210 includes a threading hole (not marked in the figure), the threading hole includes a first hole segment 1211, the axis of the first hole segment 1211 is parallel to the axis of the installation through hole 1220, and, the Part of the hole wall of the first hole section 1211 can constitute the first sub-guiding surface 1201a. The first sub-guiding surface 1201a.

Further, the threading hole may also include a second hole segment 1212 and a third hole segment 1213 . Wherein, the proximal end of the second hole section 1212 is connected to the distal end of the first hole section 1212, and part of the hole wall of the second hole section 1212 constitutes the second sub-guiding surface 1201b. The proximal end of the third hole section 1213 is connected to the distal end of the second hole section 1212 , and part of the hole wall of the third hole section 1213 constitutes the third sub-guiding surface 1201c.

Further, the surface roughness Ra of the guide surface 1201 should be as small as possible, so as to further reduce the distance between the pull wire 20 and the guide surface 1201 during the process of releasing or recovering the medical implant 2 . the resulting friction. Preferably, the surface roughness Ra of the guide surface 1201 may be less than or equal to 0.2. In some implementations, the surface roughness Ra of the guide surface 1201 can be reduced by selecting materials, for example, the wire deployment component 1200 is made of relatively smooth materials such as polytetrafluoroethylene, ceramics, and glass, or , the wire deployment part 120 includes a base material and a lubricating coating, a channel for the pull wire 20 to pass is formed on the base material, and the lubricating coating is provided on a part of the surface of the channel to form the guide surface 1201 . In other implementations, the wire deployment part 1200 may be a metal structural member, and the surface roughness Ra of the guide surface 1201 is reduced by grinding, polishing, etc. the surface of the threading channel 1210, where , the material of the wire deploying part 1200 includes but not limited to any one of titanium carbonitride, titanium nitride, stainless steel, and nickel titanium.

Optionally, the number of the threading channel 1210 is set according to actual needs, and it may be one, or two, three, or more. As shown in Figures 16 to 18, when the number of the threading channels 1210 is more than two, preferably more than two threading channels 1210 are arranged at intervals around the installation through hole 1220 to reduce the wire deployment. The radial dimension of the component 1200 thereby reduces the radial dimension of the delivery system 1 . Optionally, outlets of a plurality of threading channels 1210 are located on the same circumference, or at least part of the outlets of the threading channels 1210 are located on different circumferences.

In addition, in this embodiment, as shown in FIGS. 16 to 18 , the wire deployment component 1200 has a streamlined shape, which includes a proximal segment 1200a and a distal segment 1200b axially connected, and the proximal segment The cross-sectional area of segment 1200a gradually increases in the direction from the proximal end to the distal end. The advantage of doing this is that the bending performance of the delivery system 1 can be improved, which is beneficial for the delivery system 1 to pass through tortuous blood vessels, and at the same time, there is less interference with blood vessels and less damage to blood vessels.

In addition, in this embodiment, the wire deployment part 1200 can be an integrated component or an assembled component, as long as the threading channel 1210 and the installation through hole 1220 can be formed on the wire deployment part 1200 .

Please refer to FIG. 21 again. In another embodiment of the present invention, the wire deploying part 1200 includes at least a wire deploying part body 1230 and a rotating part 1240 . A first insertion hole is formed at the center of the wire deployment component body 1230 as at least a part of the installation through hole 1220 . The thread deployment part body 1230 is also formed with a threading groove 1231 passing through the thread deployment part body 1230 in the axial direction. Optionally, the threading groove 1231 extends along the radial direction of the thread deployment part body 1230 , and open at the edge of the wire deploying part body 1230, the threading groove 1231 is a U-shaped groove or a fan-shaped groove. The rotating member 1240 is rotatably connected to the groove wall of the threading groove 1231 , and encloses at least part of the groove wall of the threading groove 1231 to form the threading channel 1210 . The rotating member 1240 has a circumferential surface, and a partial area of the circumferential surface constitutes the guide surface 1201 . Usually, at least a partial area of the side of the circumferential surface away from the opening constitutes the guide surface 1201, that is, at least a partial area of the circumferential surface facing the installation through hole 1220 constitutes the guide surface 1201. When the distal end of the pull wire 20 passes through the threading channel 1210 and abuts against the rotating member 1240 , the extending direction of the distal end of the pull wire 20 can be deflected (as shown in FIG. 24 ). That is to say, in this embodiment, part of the surface of the rotating member 1240 is used as a support when the direction of the pull wire 20 is deflected, so that the friction force between the pull wire 20 and the wire deployment part 1200 is rolling friction. , to reduce the loss of control.

In some implementations, the wire deployment component body 1230 may have a smaller axial dimension. Here, as shown in FIGS. 22 and 23 , the wire deployment component 1200 may further include a

base

1250, and 1250 is connected to the proximal end surface of the fixing base body 1230, and the base 1250 is also provided with a second insertion hole corresponding to the first insertion hole, and the second insertion hole is in common with the first insertion hole. The installation through hole 1220 is formed. And, the base 1250 may also be provided with an introduction channel 1251 communicating with the threading channel, and the distal end of the pull wire 20 passes through the introduction channel 1251 and then passes through the threading channel 1210 . The introduction channel 1251 can be set at the position of the base 1250 corresponding to the threading channel 1201 , which can be a hole (as shown in FIG. 22 and FIG. 23 ), such as a circular hole, a square hole, and the like. It should be noted that, in the embodiment of the present invention, there is no special limitation on the setting position of the introduction channel, as long as it can allow the distal end of the pull wire 20 to pass through and enter the threading channel 1210 . In addition, it is also preferable that the cross-sectional area of the base 1250 increases gradually from the proximal end to the distal end, so as to improve the bending performance of the delivery system 1 . It can be understood that the base 1250 and the wire deployment component body 1230 can be integrally formed, or formed separately and then connected together. Alternatively, the wire deployment member body 1230 may have a larger axial dimension, in this case, preferably, the cross section of the wire deployment member body 1230 increases gradually from the proximal end to the distal end. Further, in this embodiment, the rotating member 1240 may be a rotating shaft, and the rotating shaft is mounted on the groove wall of the threading groove 1231 through a bearing. Or, an installation shaft (not shown) is formed on the opposite two groove walls of the threading groove 1231, and the rotating member 1240 is a certain pulley, and the fixed pulley is rotatably installed on the installation shaft. And, the rotating member 1240 is preferably a metal structural member, and its material includes but not limited to any one of titanium carbonitride, titanium nitride, stainless steel, and nickel titanium. Preferably, a positioning groove 1241 is provided on the circumferential surface of the rotating member 1240, and the positioning groove 1241 extends one circle along the circumferential direction of the rotating member 1240, and part of the groove wall of the positioning groove 1241 (that is, the positioning The part of the groove 1241 facing the installation through hole) constitutes the guide surface 1201 . The pull wire 20 is restricted in the positioning groove 1241 when passing through the threading passage 1210, so as to prevent the pull wire 20 from having a large movement range in the axial direction of the rotating member 1240 from causing damage to the medical device. The release or retrieval of the implant 2 has adverse effects. Further preferably, in the longitudinal section of the rotating member 1240, the positioning groove 1241 is arc-shaped. The delivery system 1 provided by the embodiment of the present invention optimizes the structure of the wire deployment part 1200 to reduce the friction force of the pull wire 20 when passing through the threading channel 1210 on the wire deployment part 1200 , to reduce the problem of loss of control force when releasing or retrieving the medical implant 2, and then achieve improving the stable release or retrieving of the medical implant 2, reducing the release or retrieving of the medical implant 2 damage to human tissue. Not only that, when the delivery system 1 releases or recovers the medical implant 2, it can also well overcome the problem of axial displacement of the medical implant 2, and improve the positioning accuracy.

The embodiment of the present invention has no special limitation on the number and setting positions of the wire deployment parts 1200 included in the delivery device, as long as the distal end of the pull wire 20 can be turned under the action of the guide surface 1201 and is compatible with the medical Implant 2 is connected. For example, the line deployment part 1200 is one (as shown in Figure 25, Figure 26, Figure 28 and Figure 29), two (as shown in Figure 27), and more (not shown in the figure), so The wire deployment part 1200 can be arranged on the proximal side and/or the distal side of the medical implant 2 (as shown in Figure 25, Figure 26 and Figure 27), and the wire deployment part can also be arranged on the The inner side of the medical implant 2 (as shown in Figure 28 and Figure 29).

In a preferred embodiment, as shown in FIG. 25 , FIG. 26 and FIG. 27 , the conveyor includes at least one wire deployment part 1200 , and in the axial direction of the conveyor system 1 , any one of the wire deployment parts 1200 The distance between the wire deployment part 1200 and the medical implant 2 is greater than or equal to zero (as shown in FIG. 25 and FIG. 27 ), and when the medical implant 2 is in the crimped state, the wire deployment The guide surface 1201 of the component 1200 deflects the extension direction of the pull wire 20 by a predetermined angle. Specifically, when the wire deployment part 1200 is arranged on the proximal side of the medical implant 2, and the distance between the distal end of the wire deployment part 1200 and the proximal end of the medical implant 2 is greater than or is equal to 0, and at the same time, the guide surface 1201 deflects the extension direction of the pull wire 20 by 90° to 135° (that is, the part of the pull wire 20 between the wire deployment part 1200 and the medical implant 2 and the The angle α formed by the axes of the conveyors is 90°-135°). And/or, the wire deployment part 1200 is arranged on the distal side of the medical implant 2, and the distance between the proximal end of the wire deployment part 1200 and the distal end of the medical implant is greater than or equal to 0 , and at the same time, the guide surface 1201 deflects the extension direction of the pull wire by 45° to 90° (that is, the part of the pull wire 20 between the wire deployment part 1200 and the medical implant 2 and the delivery The angle α formed by the axis of the device is 45°～90°). The purpose of this setting is that when the medical implant 2 is compressed, there is no axial overlap between the medical implant 2 and the wire deployment part 1200, and the two do not contact, which can improve the overall medical performance. The flexibility of the device, so that the medical device can better adapt to tortuous blood vessels. Preferably, the medical implant 2 is arranged coaxially with the inner tube 1100 .

In addition, those skilled in the art can understand that when the medical implant 2 is released and radially expanded, the part of the pull wire 20 between the wire deploying part 1200 and the medical implant 2 and the The included angle α formed by the axis of the inner tube 1100 will change accordingly. For example, when the wire deploying part 1200 is arranged on the proximal side of the medical implant 2, the medical implant After the implant 2 is released, the angle of the included angle α decreases. When the wire deployment component 1200 is arranged on the distal side of the medical implant 2, after the medical implant 2 is released, The angle of the included angle α increases.

Please refer to FIG. 10 and FIG. 11 , which show the assembly relationship between the pull wire and the conveying device. It should be understood that, in the example shown in FIG. 10 and FIG. 11 , only one pull wire in the pull wire set 02 is shown, but actually the pull wire set 02 may include multiple pull wires. In this example, the pull wire forms a single coil loop, the fixed end 022a of the pull wire is wound into a loop and fixed on the first fixed ring 213, and then the pull wire passes through the first through hole 211a of the driver 211 and extends to the distal end , then pass through the second through hole 231a of the conversion piece 231, and stretch out from the far end of the conversion piece 231 to form a loop (the loop can form a pinned relationship with other backguys in the backguy set 02, or be directly used to drive stent), and then the pull wire passes through the second through hole 231a of the conversion part 231 again, extends to the proximal end, and then passes through the first through hole 211a of the driving part 211 again, and is connected with the pin-shaped part 221. It should be understood that the example shown in Fig. 10 and Fig. 11 is only an example of the assembly relationship between the pull wire and the conveying device and is not limiting.

Please refer to FIG. 12 and FIG. 13 , in conjunction with FIG. 3 , in some embodiments, the delivery device includes more than two wire control assemblies 20 , and more than two wire fixing parts 21 of the wire control assemblies 20 The parts used to connect with the pull wire set 02 (such as the first limiting structure and the fixing structure, etc.) are staggered along the radial direction and/or circumferential direction of the delivery tube assembly 10 .

Optionally, the wire-controlled valve prosthesis includes more than two pull-wire groups 02 arranged at intervals in the axial direction, and correspondingly, the delivery device includes more than two wire-controlled assemblies 20, and each wire-controlled assembly 20 corresponds to control A cable set 02.

In some embodiments, the first limiting structures and/or fixing structures of the wire fixing parts 21 of more than two wire control assemblies 20 are coaxially arranged inside and outside around the inner tube 11 . Preferably, the first limiting structure and/or the fixing structure for controlling the wire fixing part 21 of the pull wire group 02 at the far end is located inside, and is used for controlling the first stop structure and/or fixing structure of the wire fixing part 21 of the pull wire group 02 at the proximal end. A limiting structure and/or fixing structure is located on the outside.

Taking the example shown in FIG. 3 as an example, it includes two pull wire groups 02 located at the inflow channel and the outflow channel respectively (that is, located at the far and near ends of the bracket 01 ). Correspondingly, as shown in FIG. 12 and FIG. 13 , the delivery device includes two wire control assemblies 20 , wherein the diameter of the driving member 211 of the wire control assembly 20 connected to the pull wire set 02 located at the proximal end is relatively large, The diameter of the drive element 211 of the wire control assembly 20 connected to the pull wire set 02 at the distal end is relatively small; the first through holes 211a of the two drive elements 211 are respectively arranged coaxially around the axis of the inner tube. Further, the two driving parts 211 are respectively connected to one puller tube 212 , so that the two driving parts 211 can be driven independently, so that the two wire fixing parts 21 can move independently of each other along the axial direction of the delivery tube assembly 10 . With such a configuration, the two wire control assemblies 20 can independently drive their corresponding pull wire groups 02 without mutual interference. Of course, in some other embodiments, the wire fixing parts 21 of the two wire control assemblies 20 are fixed to each other, for example, the two driving parts 211 are connected to the same pull wire tube 212, at this time, the two pull wire groups 02 will be driven simultaneously to retract. Tight or loose.

It should be understood that the wire fixing parts 21 of the two wire control assemblies 20 are fixed to each other, not only can it be understood that the two wire control assemblies 20 have their own independent driving parts 211, as shown in Figure 14 and Figure 15, in some embodiments Among them, the two wire control assemblies 20 can also share the same driving part 211, which can also be understood as the driving parts 211 of the two wire control assemblies 20 are fused with each other and integrally formed. Further, the parts (such as the first through hole 211 a ) of the wire fixing parts 21 of more than two wire control assemblies 20 used to connect with the pull wire group are arranged in a staggered circumferential direction around the inner tube 11 to prevent the pull wires from intersecting and scratching each other. When the wire fixing parts 21 of the two wire control assemblies 20 are fixed to each other, the two pull wire groups 02 will be driven simultaneously to tighten or loosen. Of course, the wire disengagement parts 22 of the two wire control assemblies 20 are not limited to be controlled simultaneously, but preferably can be driven independently. Preferably, only one dismantling wire 022 and multiple fixing wires 021 are set in each pull wire group 02, and correspondingly, only one wire disengagement part 22 can be set in each wire control assembly 20, and the structure of the conveying device is simple and easy to use After separating the dismantling line 022 of a backguy group 02, the backguys connected by the rest of the pins can be released. Simplified the steps of thread withdrawal operation.

Optionally, in some embodiments, the pull wire set 02 can be integrated into the conveying device, that is, the conveying device includes at least one pull wire set 02, and the pull wire set includes at least one pull wire. Please refer to the above for the specific structure and configuration of the pull wire group 02, and will not repeat them here.

It should be noted that the above several embodiments can be combined with each other. The above description is only a description of the preferred embodiments of the present invention, and does not limit the scope of the present invention. Any changes and modifications made by those of ordinary skill in the field of the present invention based on the above disclosures shall fall within the protection scope of the claims.

Claims

An implant delivery device, characterized by comprising: a delivery tube assembly and at least one wire control assembly; the wire control assembly includes: a wire fixing part and a wire detaching part;

The wire fixing part is used to connect with the fixed end of the stay wire in the stay wire set;

The wire detachment part is movably arranged along the axial direction of the delivery tube assembly, and the wire detachment part is used to connect with the detachment end of the pull wire in the pull wire group; when the wire detachment part satisfies the preset condition , the wire disengagement part is disengaged from the disengagement end of the pull wire.
The implant delivery device according to claim 1, characterized in that, the wire fixing member is movably arranged along the axial direction of the delivery tube assembly.
The implant delivery device according to claim 2, characterized in that, the wire detachment part is located at the proximal end of the wire fixing part, and when the wire detachment part does not meet the preset condition, the wire detachment part Moves in the axial direction of the delivery tube assembly synchronously with the wire fixing member.
The implant delivery device according to claim 2, wherein the delivery tube assembly includes an inner tube, and the wire fixing component is movably sleeved outside the inner tube.
The implant delivery device according to claim 1, wherein the preset condition includes mechanical movement of the wire breaking away component.
The implant delivery device according to claim 5, wherein the wire disengagement member comprises a pin-shaped member having an opening for receiving the disengagement end of the pull wire. connection; the predetermined condition includes: the wire disengagement member moves relative to the disengagement end of the pull wire, so that the disengagement end of the pull wire disengages from the opening.
The implant delivery device according to claim 6, characterized in that, the delivery device further comprises a traction member, the first end of the traction member is connected to the pin-shaped member, and the second end of the traction member The end extends proximally.
The implant delivery device according to claim 1, characterized in that, when the detachment end of the pull wire is connected to the wire detachment part, the wire detachment part is in a connected state, and at this time the wire control assembly The axial distance from the distal end of the delivery device is no greater than 300mm.
The implant delivery device according to claim 1, characterized in that, the wire fixing part comprises a driving part, and the driving part is movably arranged along the axial direction of the delivery tube assembly; the driving part has A first limiting structure, the first limiting structure is used to limit the circumferential position of the pull wire around the delivery tube assembly.
The implant delivery device according to claim 9, characterized in that, the first limiting structure includes a plurality of first through holes opened through the axial direction of the driving member, or, the first The limiting structure includes a plurality of first grooves opened on the outer periphery of the driving member along the axial direction of the driving member; the first through hole or the first groove is used for passing the pull wire.
The implant delivery device according to claim 10, wherein the wire fixing part further comprises a fixing structure, and the fixing structure is used to be connected with the fixing end of the pulling wire.
The implant delivery device according to claim 11, characterized in that, the two different first through holes are used for the same pull wire to pass through and wind in turn, and the driving member is different from the one on it. The two first through holes are jointly configured as the fixing structure.
The implant delivery device according to claim 11, wherein the fixing structure comprises: a first fixing ring, the first fixing ring is used for wrapping around the fixing end of the pull wire;

The radially inner dimension of the first fixing ring is smaller than the radially outer dimension of the driving member, and the first fixing ring is used to abut against the driving member; or

The first fixing ring is fixedly sleeved on the outer periphery of the driving member.
The implant delivery device according to claim 1, wherein the wire control assembly further comprises: a wire deployment component; the delivery tube assembly includes an inner tube;

The wire deploying part is fixedly connected with the inner tube; the wire deploying part is used for changing the extending direction of the pulling wire to along the radial direction of the delivery tube assembly after the pulling wire converges on it Axial extension of the delivery tube assembly described above.
The implant delivery device according to claim 14, characterized in that, the wire deployment part comprises a transition piece, the transition piece has a second limiting structure, and the second limiting structure is used to limit the A pull wire surrounds a circumferential location of the delivery tube assembly.
The implant delivery device according to claim 15, characterized in that, the second limiting structure includes a plurality of second through holes opened through the axial direction of the conversion member; or, the second The limiting structure includes a plurality of second grooves opened on the outer periphery of the conversion member along the axial direction of the conversion member; the second through hole or the second groove is used for passing the pull wire.
The implant delivery device according to claim 15, wherein the wire deployment part further comprises a transition structure, and the transition structure is used to gradually change the extension direction of the pull wire.
The implant delivery device according to claim 17, wherein the transition structure comprises: a second fixing ring;

The second fixing ring is fixedly arranged relative to the conversion element, and the second fixing ring is used for winding the pull wire to change the extending direction.
The implant delivery device according to claim 17, wherein the conversion member has a hole opened along the axial direction of the delivery tube assembly, and the second limiting structure includes a plurality of holes along the conversion direction. The third through hole opened in the radial direction of the member and communicated with the channel; the transition structure includes the third through hole; the channel and the third through hole are used to pass through the pull wire to change the extension direction.
The implant delivery device according to claim 14, wherein a threading channel is formed on the wire deployment part, and a part of the surface of the threading channel is formed as a smooth guide surface, and the guide surface is used for The pull wire is supported when the pull wire passes through the threading channel, and the extending direction of the pull wire is deflected.
The implant delivery device according to claim 20, wherein the guide surface comprises a first sub-guidance surface, a second sub-guidance surface and a third sub-guidance surface which are sequentially and smoothly connected from the proximal end to the distal end. surface, wherein the axes of the first sub-guiding surface and the third sub-guiding surface are straight lines, and the angle formed by the axis of the first sub-guiding surface and the axis of the third sub-guiding surface is The angle is 45°-135°, and the axis of the second sub-guiding surface is an arc.
The implant delivery device according to claim 21, characterized in that, the threading channel includes a threading hole, and the threading hole includes a first hole segment, and part of the hole wall of the first hole segment constitutes the second hole wall. A sub-guiding surface.
The implant delivery device according to claim 22, wherein the threading hole further comprises a second hole segment and a third hole segment; the proximal end of the second hole segment is connected to the first hole segment The distal end of the second hole segment communicates with the second sub-guiding surface, the proximal end of the third hole segment communicates with the distal end of the second hole segment, and the third hole segment Part of the hole wall of the segment constitutes said third sub-guiding surface.
The implant delivery device according to claim 21, wherein the wire deployment member comprises a proximal portion and a distal portion axially connected, and the cross-sectional area of the proximal portion is along the proximal direction. The direction of the distal end gradually increases.
The implant delivery device according to claim 20, characterized in that, the wire deploying part comprises a wire deploying part body and a rotating part, and the wire deploying part body is formed with a threading groove extending through and extending along its axial direction. , the rotating member is rotatably connected to the groove wall of the threading groove, and forms the threading channel with at least part of the groove wall of the threading groove; the rotating member has a circumferential surface, and the circumferential surface A part of the area constitutes the guide surface.
The implant delivery device according to claim 25, characterized in that, the threading groove extends radially along the body of the wire deployment part and opens at the edge of the body of the wire deployment part, and the rotating At least a partial area of the side of the circumferential surface of the member facing away from the opening forms the guide surface.
The implant delivery device according to claim 25, wherein a positioning groove extending one circle along the circumferential direction of the rotating member is formed on the peripheral surface of the rotating member, and a part of the positioning groove is A wall forms the guide surface.
The implant delivery device according to claim 27, characterized in that, on the longitudinal section of the rotating member, the positioning groove is arc-shaped.
The implant delivery device according to claim 25, wherein the wire deployment part further comprises a base, the base is connected to the proximal end surface of the wire deployment part body, and the base is provided with An introduction channel connected with the threading channel, and the cross-sectional area of the base gradually increases from the proximal end to the distal end.
The implant delivery device according to any one of claims 20-29, characterized in that, the wire deployment part is further provided with an installation through hole, so that the wire deployment part can be fitted into the target tube body Above; the number of the threading channel is at least one, and when the number of the threading channel is multiple, a plurality of the threading channels are arranged at intervals around the installation through hole.
The implant delivery device according to any one of claims 20-29, characterized in that, the surface roughness Ra of the guide surface is less than or equal to 0.2.
The implant delivery device according to claim 1, characterized in that, the implant delivery device comprises more than two wire control assemblies, and more than two wire fixing parts of the wire control assemblies The parts used for connecting with the puller group are staggered with each other along the radial direction and/or circumferential direction of the delivery tube assembly.
The implant delivery device according to claim 32, characterized in that, the wire fixing parts of more than two wire control assemblies are fixed to each other; or, the wire fixing parts of more than two wire control assemblies The wire fixing members move independently of each other along the axial direction of the delivery tube assembly.
The implant delivery device according to claim 1, characterized in that, the pulling wire group includes a plurality of the pulling wires, and the wire fixing part is used for converging and connecting fixed ends of the plurality of pulling wires.
The implant delivery device according to claim 1, characterized in that the delivery device further comprises at least one puller wire set, and the puller wire set includes at least one puller wire.