WO2022227911A1

WO2022227911A1 - Adjustable stent-type thrombectomy device

Info

Publication number: WO2022227911A1
Application number: PCT/CN2022/081333
Authority: WO
Inventors: 彭亚; 李�真; 邢雷; 戴威骏
Original assignee: 常州凯尼特医疗科技有限公司
Priority date: 2021-04-30
Filing date: 2022-03-17
Publication date: 2022-11-03
Also published as: CN113520519A

Abstract

An adjustable stent-type thrombectomy device, comprising an expandable stent (10) that comprises a proximal end and a distal end (11); a cannula (30), the distal end of the cannula (30) being connected to the proximal end of the expandable stent (10), the proximal end of the cannula (30) being provided with a connector (32), and the connector (32) having a fixing point and an opening (321); a first operating wire (21) that passes through the opening (321) and is slidable in the cannula (30), the first operating wire (21) being fixedly connected to the distal end (11) of the expandable stent (10); and a second operating wire (22) that is fixedly connected to the fixing point of the connector (32), the proximal ends of the first operating wire (21) and the second operating wire (22) being used for handheld operation outside the body. In the present invention, no operation handle is needed, and not only is the expansion diameter of the stent controllable, but because the expansion and contraction of the stent can be realized by means of relative movement between a support wire and a traction wire, the operation controllability is increased, and control can be conducted by both the left and right hands together, without needing to consider the problem of control habit by one single hand. In addition, the first operating wire (21) and the second operating wire (22) can be operated independently, such that the problem of extending to the distal end (11) during the contraction of the expandable stent (10) can be prevented, thus reducing the possibility of accidental fall off of thrombi.

Description

An adjustable bracket type thrombus removal device

technical field

The invention relates to the field of interventional medical instruments, in particular to an adjustable stent-type thrombectomy device.

Background technique

The principle of cerebral artery stent thrombectomy is to use the microcatheter technology. The stent thrombectomy device reaches the intracranial artery along the lower extremity artery through the arterial channel in the body, and then the thrombectomy device at the front of the catheter actively "captures" the thrombus blocking the blood vessel and restores the blood vessel. unobstructed. During the operation, the doctor only needs to make an incision in the patient's thigh, and then the stent can be sent into the blood vessel to reach the diseased site, saving the patient the pain of undergoing craniotomy.

Chinese invention patent CN109223107A discloses a thrombus removal device, including: a bolus removal bracket, a delivery system and a push handle. Through the cooperation between the push handle shell and the push handle, the control of the expandable stent is realized. However, it is known from clinical experience that there are habitual problems with one-handed control, and there is also the problem of poor operation feel. In addition, expandable stents instead extend distally during retraction, increasing the likelihood of accidental thrombus dislodgement during retrieval.

At the same time, when the existing thrombectomy stent is in use, during the withdrawal of the stent, due to the small space in the inner lumen of the guide catheter, the thrombectomy stent will accumulate at the distal end during the withdrawal process. The accumulation phenomenon will affect the smooth withdrawal of the thrombectomy stent into the guide catheter, and may even lead to the thrombus falling off or the failure of thrombectomy in severe cases.

SUMMARY OF THE INVENTION

The invention discloses an adjustable bracket-type thrombectomy device, aiming at solving the technical problems existing in the prior art.

The present invention adopts following technical scheme:

An adjustable stent-type thrombectomy device, comprising: an expandable stent, including a proximal end and a distal end, the expandable stent can radially expand or collapse when the distance between the proximal end and the distal end is compressed or stretched; A sleeve, the distal end of the sleeve is connected to the proximal end of the expandable stent, and the proximal end of the sleeve is provided with a connecting piece; the connecting piece has a fixing point and a perforation; the first operating wire passes through the perforation and can slide in the sleeve; An operation wire is fixedly connected with the distal end of the expandable stent; the second operation wire is fixedly connected to the fixing point of the connector; the proximal ends of the first operation wire and the second operation wire are used for external hand-held operation.

As a preferred technical solution, the expandable stent includes a metal woven mesh stent or a laser engraved mesh stent.

As a preferred technical solution, the expandable stent converges on the distal end, and/or the expandable stent converges on the proximal end.

As a preferred technical solution, the second operation wire has higher mechanical strength than the first operation wire.

As a preferred technical solution, the second manipulation wire has a larger diameter than the first manipulation wire.

As a preferred technical solution, the second operation wire adopts a material with higher mechanical strength than the first operation wire.

As a preferred technical solution, the distal end and the proximal end of the first operation wire and/or the second operation wire have different diameters.

As a preferred technical solution, the distal end of the first operation wire and/or the second operation wire has a smaller diameter than the proximal end.

As a preferred technical solution, the proximal portion of the first operating wire and/or the second operating wire has a non-slip surface.

As a preferred technical solution, the distal portion of the first operating wire and/or the second operating wire has a smooth surface.

As a preferred technical solution, the non-slip surface is a non-slip coating, or a non-slip scribe, or an anti-slip glue layer.

As a preferred technical solution, the smooth surface is a hydrophilic coating.

As a preferred technical solution, the proximal portion of the first operating wire and/or the second operating wire is marked with a color.

As a preferred technical solution, the proximal end sections of the first operation wire and the second operation wire are marked with different colors.

As a preferred technical solution, the first operation wire and the second operation wire respectively have multiple sections of different color marks.

As a preferred technical solution, the expandable stent, and/or the first operating wire, and/or the second operating wire are made of nickel-titanium alloy material or developable alloy material.

As a preferred technical solution, the distal end of the expandable stent has a developing spring.

As a preferred technical solution, the first developing ring at the distal end of the expandable stent.

As a preferred technical solution, the proximal end of the expandable stent has a second developing ring.

As a preferred technical solution, a catheter is also included, and the catheter can accommodate the expandable stent in a collapsed state therein.

As a preferred technical solution, the distal end of the catheter has a third developing ring.

As a preferred technical solution, it further includes: a first operation part, which is detachably fixed to the first operation wire; and a second operation part, which is detachably fixed to the second operation wire.

As a preferred technical solution, the first operating portion includes a first housing and a second housing that are oppositely disposed and separable; a first housing for accommodating and fixing the first operating wire is defined between the first housing and the second housing. fixed slot;

The second operating portion includes a third housing and a fourth housing that are disposed oppositely and are separable; a second fixing groove for accommodating and fixing the second operating wire is defined between the third housing and the fourth housing.

As a preferred technical solution, the second operation part has a larger size than the first operation part.

As a preferred technical solution, a side surface of the first operating portion has a first limiting portion; a side surface of the second operating portion has a second limiting portion, and the second limiting portion has a plurality of limiting positions; the first limiting portion It can be detachably connected with multiple limit positions of the second limit part.

As a preferred technical solution, the first limiting portion is a rack snap protrusion; the second limiting portion is a rack snap groove, which can define multiple limiting positions; the rack snap protrusion can be inserted into the rack snap groove Multiple limit positions in .

As a preferred technical solution, the second limiting portion is a card slot, and the card slot can define multiple limiting positions; the first limiting portion is a locking protrusion, and the locking protrusion can be inserted into the multiple limiting positions in the card slot.

As a preferred technical solution, the first operation part and/or the second operation part includes scale marks.

As a preferred technical solution, the first operation part and/or the second operation part has a non-slip gripping part.

As a preferred technical solution, it also includes: a third operation part; the third operation part includes a fifth casing and a sixth casing sleeved on the first operation wire and the second operation wire, and the fifth casing can be relative to the first operation wire and the sixth casing. The six housings rotate to limit the relative movement of the first operating wire and the second operating wire.

The technical solution adopted in the present invention can achieve the following beneficial effects: the adjustable stent-type thrombectomy device of the present invention does not need to operate a handle, not only the expansion diameter of the stent is controllable, but also the relative movement between the support wire and the traction wire realizes the expansion of the stent. The expansion and contraction make the operation more controllable, and the left and right hands can be controlled together, so there is no need to consider the habitual problem of one-handed control. At the same time, since the first operation wire and the second operation wire can be independently controlled, the problem of extending to the distal end during the contraction of the expandable stent can be avoided, and the possibility of accidental thrombus falling off can be reduced.

Description of drawings

In order to illustrate the technical solutions of the embodiments of the present invention more clearly, the following briefly introduces the accompanying drawings used in the description of the embodiments, which constitute a part of the present invention, and the exemplary embodiments of the present invention and their descriptions explain the present invention. , does not constitute an improper limitation of the present invention. In the attached image:

1 is a schematic perspective view of the adjustable stent-type thrombectomy device disclosed in Embodiment 1 of the present invention;

2 is a schematic perspective view of the adjustable stent-type thrombectomy device disclosed in Embodiment 1 of the present invention;

Fig. 3 is a partial enlarged view of Fig. 2;

4A is a schematic diagram of the adjustable stent-type thrombectomy device disclosed in Embodiment 1 of the present invention in a retracted state;

4B is a schematic diagram of the adjustable stent-type thrombectomy device disclosed in Embodiment 1 of the present invention in an expanded state;

5 is a schematic diagram of the adjustable stent-type thrombectomy device disclosed in Embodiment 2 of the present invention;

6 is a schematic diagram of the adjustable stent-type thrombectomy device disclosed in Embodiment 3 of the present invention;

7 is a schematic diagram of the adjustable stent-type thrombectomy device disclosed in Embodiment 4 of the present invention;

8 is a schematic diagram of the adjustable stent-type thrombectomy device disclosed in Embodiment 4 of the present invention;

9 is a schematic diagram of the adjustable stent-type thrombectomy device disclosed in Embodiment 4 of the present invention;

10 is a schematic diagram of the adjustable stent-type thrombectomy device disclosed in Embodiment 4 of the present invention;

11 is a schematic diagram of the adjustable stent-type thrombectomy device disclosed in Embodiment 5 of the present invention;

12 is a schematic view of the operating state of the adjustable stent-type thrombectomy device disclosed in Embodiment 5 of the present invention;

FIG. 13 is a schematic diagram of the operation state of the adjustable stent-type thrombectomy device disclosed in Embodiment 5 of the present invention.

Description of reference numbers:

Expandable stent 10; expandable stent distal end 11; development spring 111; first operation wire 21; second operation wire 22; first operation wire proximal section 21'; second operation wire proximal section 22'; sleeve 30; sleeve distal end 31; first developing ring 112; second developing ring 113; connecting piece 32; perforation 321; catheter 40; third developing ring 411;

The first operating part 50; the first housing 51; the second housing 52; the first hinge 56; the first limiting part 57; the first rack 571;

The second operating part 60; the third housing 61; the fourth housing 62; the first fixing groove 63; the inserting part 64; 671; the second anti-skid handle portion 68.

The third operation part 70 ; the fifth casing 71 ; the sixth casing 72 .

Detailed ways

In order to make the objectives, technical solutions and advantages of the present invention clearer, the technical solutions of the present invention will be clearly and completely described below with reference to the specific embodiments of the present invention and the corresponding drawings. In the description of the present invention, it should be noted that the term "or" is generally used in its sense including "and/or" unless the content clearly dictates otherwise.

In the description of the present invention, those skilled in the art should understand that, unless otherwise expressly specified and limited, the terms "proximal end" and "distal end" are relative to the operator; "proximal end" refers to the After the thrombus stent enters the human blood vessel, it is closer to the user in the one-dimensional direction defined by the human blood vessel, and the "distal end" is farther away from the user in the one-dimensional direction defined by the human blood vessel. And those skilled in the art should understand that the far and near do not refer to the straight-line distance from the user in three-dimensional space.

Obviously, the described embodiments are only some, but not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

The present application provides an adjustable stent-type thrombectomy device, comprising: an expandable stent, including a proximal end and a distal end; a sleeve 30, the distal end of the sleeve 30 is connected to the proximal end of the expandable stent, and the proximal end of the sleeve 30 is connected to the proximal end of the sleeve 30. The end has a connecting piece 32; the connecting piece 32 has a fixing point and a through hole 321; the first operation wire 21 passes through the through hole 321 and can slide in the cannula 30, and the first operation wire 21 is fixed with the distal end of the expandable stent Connection; the second operation wire 22 is fixedly connected to the fixed point of the connector 32; the proximal ends of the first operation wire 21 and the second operation wire 22 are used for external hand-held operation.

Example 1

This example 1 will be described with reference to FIGS. 1-4B . This embodiment provides an adjustable stent-type thrombectomy device, including: an expandable stent 10, two ends of the expandable stent 10 can be defined as a proximal end and a distal end 11, corresponding to the right end and the left end in FIG. 2, respectively, The expandable stent 10 can radially expand or collapse when the distance between the proximal end and the distal end is compressed or stretched; the expandable stent 10 cannot self-expand, and the relative movement of the support wire and the traction wire needs to be controlled to achieve expansion and contraction . Specifically, when the distal end is close to the proximal end, the expandable stent 10 can convert the axial pressure into a radial expansion force, so that the expandable stent 10 is gradually expanded to a size matching the inner diameter of the blood vessel, so as to realize the intravascular pressure. thrombus extraction. Those skilled in the art should understand that the distance between the proximal end and the distal end 11 of the expandable stent 10 is generally inversely related to the diameter of the expandable stent 10 .

According to FIGS. 1-2 , the thrombectomy stent has a cannula 30 , the distal end of the cannula 30 is connected to the proximal end of the expandable stent 10 , and the proximal end of the cannula 30 has a connector 32 . According to FIG. 3 , the connecting piece 32 has a fixing point and a through hole 321 . Preferably, the length of the sleeve 30 is 100-500 mm, and in a preferred solution, the length of the sleeve 30 is 350 mm.

The first operating wire 21, preferably providing a traction function, passes through the hole 321 and can slide in the cannula 30, and the first operating wire 21 is fixedly connected with the distal end 11 of the expandable stent 10; through the movement of the first operating wire 21, The position of the distal end 11 of the expandable stent 10 can be changed; the second operation wire 22 preferably provides a supporting function, and is fixedly connected to the fixed point of the connecting piece 32 , and the proximal end of the expandable stent 10 can be changed through the movement of the second operation wire 22 s position.

According to FIG. 4A and FIG. 4B , by changing the relative positions of the first operating wire 21 and the second operating wire 22 , the expansion degree of the expandable stent 10 can be changed. The proximal ends of the first operating wire 21 and the second operating wire 22 are used for external hand-held operation without the need to use a handle for one-handed operation, which not only improves the doctor's hand feeling during operation with both hands, but also helps to maintain the catheter during thrombectomy. of negative pressure.

Preferably, according to FIGS. 1 , 12 and 13 , the expandable stent 10 includes a metal braided mesh stent, preferably a nickel-titanium wire braided mesh stent. As an alternative, the mesh stent may also include a non-metallic material. In another specific embodiment, according to FIG. 2 , the expandable stent 10 can be a metal laser engraved mesh stent, and its natural state can be a collapsed state or an expanded or semi-expanded state, preferably the metal laser engraved stent It has a lower elastic coefficient, preferably the stent mesh has a smaller size, so that it can realize the controllable adjustment of contraction and expansion under the control of the first operating wire 21 and the second operating wire 22, and at the same time, it can also obtain The expansion stent 10 has wider and more flexible outer diameter adjustment and reduces product specifications. The metal laser-engraved mesh stent can be made of memory alloy, but those skilled in the art should understand that its elasticity coefficient is lower than that of the conventional natural expansion memory alloy thrombectomy stent in the art.

Preferably, the expandable stent 10 converges at the distal end, and/or, the expandable stent 10 converges at the proximal end. According to Figure 1, the expandable stent 10 converges at both the proximal and distal ends.

Preferably, the distal end 11 of the expandable stent 10 has a developing spring 111 . So that the doctor who performs interventional surgery can obtain the distal position and state of the expandable stent 10 with the help of the X-ray machine. The developing spring 111 is preferably arc-shaped or curved, so as to facilitate the smooth passage of blood vessel branches.

Preferably, the distal end of the expandable stent 10 also has a first developing ring 112 at the position where the distal end of the expandable stent 10 engages with the developing spring 111 .

Preferably, the position where the proximal end of the expandable stent 10 engages with the sleeve 30 also has a second developing ring 113 , and the second developing ring 113 can also be regarded as being disposed at the proximal end of the expandable stent 10 where the proximal end converges. Considered to be disposed at the distal end of the cannula 30 .

The first developing circle 112 and the second developing circle 113 can be clearly seen under X-rays, and the distance between them can more accurately characterize the state of the expandable stent 10 and assist in judging the expansion state of the stent.

Preferably, the second operation wire 22 should have a higher mechanical strength than the first operation wire 21 because the second operation wire 22 has to bear against the retracting force during the pulling process of the first operation wire 21 . The way to increase the mechanical strength can be chosen by using different diameters or using different materials.

Preferably, the second manipulation wire 22 has a larger diameter than the first manipulation wire 21 . As a preferred solution, both the first operating wire 21 and the second operating wire 22 are made of nickel-titanium alloy wires. Preferably, the diameter of the first operation wire 21 is 0.1-0.3 mm, the diameter of the second operation wire 22 is 0.2-0.4 mm, and the diameter of the second operation wire 22 is larger than that of the first operation wire 21 . The selection of the diameters of the first operating wire 21 and the second operating wire 22 will greatly affect the doctor's operating feel. In a preferred embodiment, in order to be suitable for thrombectomy of cerebral blood vessels, the diameter of the first operation wire 21 is set to be 0.2 mm, and the diameter of the second operation wire 22 is set to be 0.25 mm.

Preferably, the second operating wire 22 is made of a material with higher mechanical strength than the first operating wire 21, such as a different kind of alloy material. Preferably, the expandable stent 10, and/or the first operating wire 21, and/or the second operating wire 22 can be made of nickel-titanium alloy material, or stainless steel, or can be made of or contain a developable alloy material, such as The metals platinum and iridium, or platinum-iridium alloys. The expandable stent 10 can also be selected from non-metallic materials, such as polylactic acid.

Preferably, the adjustable stent-type thrombectomy device of this embodiment further includes a catheter 40, and the catheter 40 can accommodate the expandable stent 10 in a collapsed state therein. Preferably, the inner diameter of the conduit 40 is 0.4-0.8 mm, and in a preferred solution, the inner diameter of the conduit 40 is 0.53 mm. Preferably, the distal end of the catheter 40 has a third imaging ring 411 for imaging and locating whether the catheter 40 passes through the thrombus. The catheter 40 can be selected from conventional microcatheters of 6F or greater than 6F, or can be an 8F balloon catheter.

The following describes the implementation method of the adjustable stent-type thrombectomy device of the present embodiment in conjunction with the implementation process of the interventional operation:

A guide catheter 40 with a thick guide wire is first delivered to the carotid artery, then the guide wire is delivered, followed by the catheter 40, to and through the distal end of the thrombus. After that, the adjustable stent-type thrombectomy device of this embodiment is delivered, and the position of the developing spring 111 of the adjustable stent-type thrombectomy device just reaches the position of the second developing ring at the distal end of the catheter 40, the catheter 40 is withdrawn, and then the expandable stent 10 is performed. expansion operation.

After the micro-guide wire passes through the distal end of the thrombus, the micro-catheter 40 follows the path established by the guide wire and also passes through the distal end of the thrombus, and then completely retracts the micro-guide wire, and then delivers the adjustable stent-type thrombectomy device of this embodiment. Until the position of the developing spring 111 of the adjustable stent-type thrombectomy device just reaches the position of the third developing ring 411 at the distal end of the microcatheter 40, then keep the position of the adjustable stent-type thrombectomy device still, and withdraw the catheter 40 until the adjustable stent-type thrombectomy device can be adjusted. The second developing ring 113 of the stent-type thrombectomy device has just completely exposed the distal end of the catheter 40 , and then the expansion operation of the expandable stent 10 is performed.

During the expansion operation, the position of the second operation wire 22 can be maintained, the first operation wire 21 can be pulled for expansion, and after the expansion is in place, the relative position of the first operation wire 21 and the second operation wire 22 can be maintained for a period of time, The adjustable stent-type thrombectomy device is retracted together with the catheter 40 to the vicinity of the guide tube orifice. Hold the position of the second operating wire 22 and push the first operating wire 21 to make the expandable stent 10 shrink slightly; or hold the position of the first operating wire 21 and pull the second operating wire 22 to make the expandable stent 10 shrink slightly. The expandable stent 10 can be contracted while the center of the stent is slightly displaced proximally. This process is different from the existing operation, and can ensure that the center of the stent and any part of the stent will only be displaced proximally during the contraction of the expandable stent 10, while Does not move to the far end.

After that, partially withdraw the expandable stent 10 into the guide catheter, withdraw the adjustable stent-type thrombectomy device and the microcatheter 40 of this embodiment together, check the thrombus condition, and re-enter the thrombectomy operation as needed; When the expandable stent 10 is used, the possible accumulation phenomenon at the distal end is reduced, and the accidental fall of the thrombus on the expandable stent 10 is avoided.

Due to the operational flexibility of the adjustable stent-type thrombectomy device of this embodiment, an experienced interventional surgeon can even operate the first operating wire 21 and the second operating wire 22 simultaneously, respectively, providing flexibility for the expandable stent 10 . Control, and bring more operation possibilities to the doctor with a good operation feel, so as to avoid the doctor's operation idea being limited to the limited adjustment method of the existing operation handle.

Example 2

Embodiment 2 presents a preferred adjustable stent-type thrombectomy device. According to FIG. 5 , it is different from Embodiment 1 in that the distal end and proximal end of the second operating wire 22 have different diameters. Preferably, the distal end of the second operating wire 22 has a smaller diameter than the proximal end. The part of the second operation wire 22 that enters the body should have a smaller diameter, but in this embodiment, a variable diameter design is adopted, and the part of the second operation wire 22 outside the body has a larger diameter than the inner part, which makes this part The segment has higher mechanical strength, better grip, and is more conducive to locking the relative positions of the first operating wire 21 and the second operating wire 22 when necessary.

The proximal section 22' (ie the large diameter section) and the small diameter section of the second operating wire 22 may be a smooth transition, that is, a variable diameter wire made of the same material as a whole, or a wire of two diameters may be used to connect production.

As a preferred embodiment, the first operating wire 21 can also adopt the same design as the second operating wire 22 . The distal and proximal pages of the first operating wire 21 may have different diameters. Preferably, the distal end of the first operating wire 21 has a smaller diameter than the proximal end, as shown in FIG. 5 . In order to improve the operability of the hand-held operation part section, the operation experience is further improved.

Those skilled in the art should understand that the lengths of the proximal section 21 ′ of the first operation wire 21 and the proximal section 22 ′ of the second operation wire 22 shown in FIG. 5 are not actual lengths, and their actual lengths may be 200-500 mm , and preferably, in order to ensure support, the lengths of the proximal section 21 ′ of the first operation wire 21 and the proximal section 22 ′ of the second operation wire 22 with relatively larger diameters may be 200-1600 mm.

Example 3

Embodiment 3 On the basis of Embodiment 2, in order to improve the hand-held operability and recognizability of the first operating wire 21 and the second operating wire 22, various preferred adjustable stent-type thrombectomy devices are provided.

The distal portion sections of the first manipulation wire 21 and/or the second manipulation wire 22 have a smooth surface, preferably the smooth surface is a hydrophilic coating.

The proximal end section of the first operating wire 21 and/or the second operating wire 22 has a non-slip surface, preferably, the non-slip surface is a non-slip coating, or a non-slip score, or a non-slip glue layer.

Preferably, the proximal section 21' of the first operating wire 21 and/or the proximal section 22' of the second operating wire 22 form a non-slip surface.

According to FIG. 5 , in Embodiment 3, it is preferable that the proximal end portion of the first operating wire 21 and/or the second operating wire 22 has a color mark. Preferably, the proximal end sections of the first operation wire 21 and the second operation wire 22 have different color markings, for example, the proximal end section 21 ′ of the first operation wire 21 has a substantially darker color, and the second operation wire 22 has a substantially darker color. The proximal section 22' has a generally lighter color. It can also be different colors or color temperatures. For example, the proximal section 21' of the first operating wire 21 is a warm color, such as red, yellow, orange, etc., and the proximal section 22' of the second operating wire 22 is a cool color. such as blue, green, purple, etc. In a preferred embodiment, one of the proximal section 21' of the first operation wire 21 and the proximal section 22' of the second operation wire 22 is marked with a color, and the other is a metallic color.

According to FIG. 6 , as a further preferred embodiment, the first operating wire 21 and the second operating wire 22 respectively have multiple sections of different color marks. Preferably, both the proximal end section 21' of the first operation wire 21 and the proximal end section 22' of the second operation wire 22 have multiple sections of different color marks. Preferably, both the proximal section 21' of the first operating wire 21 and the proximal section 22' of the second operating wire 22 are formed by alternately arranging light and dark blocks of the same color. Further preferably, the proximal section 21' of the first operation wire 21 is formed by, for example, alternating dark blue sections and light blue sections, and the proximal section 22' of the second operation wire 22 is, for example, alternating dark yellow sections and light yellow sections. arranged to form.

Preferably, the proximal section 21' of the first operating wire 21 and the proximal section 22' of the second operating wire 22 are formed by alternately arranging different color segments and white/metallic color segments. Preferably, the proximal section 21' of the first operating wire 21 is formed by, for example, a blue color section and a metallic natural color section being alternately arranged, and the proximal section 22' of the second operating wire 22 is, for example, a dark orange color section and a metallic natural color section. Alternately arranged.

In another preferred embodiment, the color signs of the proximal section 21' of the first operation wire 21 and the proximal section 22' of the second operation wire 22 are respectively continuous gradient or step gradient color of the same color system.

In the above specific embodiment, the alternately arranged different color segments can not only clearly distinguish the first operating wire 21 and the second operating wire 22, but also can indicate the relative position change relationship between the first operating wire 21 and the second operating wire 22 in real time, Assist doctors in operating perception.

Example 4

This embodiment 4 provides a preferred adjustable stand-type thrombus retrieval device, which provides an auxiliary component for hand-held operation according to FIGS. 7-11 . This solution is especially applicable to the adjustable stent-type thrombectomy device in Example 2. Under the condition that the proximal section 21' of the first operation wire 21 and the proximal section 22' of the second operation wire 22 have a certain mechanical strength, During the doctor's operation, the hand-held operation position does not need to be close to the catheter 40 or the sheath, and auxiliary parts can be used for fine operation and mutual positioning.

The auxiliary components include: a first operation part 50 , which is detachably fixed to the first operation wire 21 ; and a second operation part 60 , which is detachably fixed to the second operation wire 22 .

According to FIG. 8 , the first operating portion 50 includes a first housing 51 and a second housing 52 that are oppositely disposed and separable; the first housing 51 and the second housing 52 are defined between the first housing 51 and the second housing 52 to accommodate and fix the first operating wire 22 of the first fixing slot.

According to FIGS. 9-10 , preferably, the second operating portion 60 includes a third housing 61 and a fourth housing 62 that are oppositely disposed and separable; the third housing 61 and the fourth housing 62 define a receiving and The second fixing groove 63 for fixing the second operating wire 22; the third casing 61 and the fourth casing 62 each have a plurality of interlocking parts 64; the third casing 61 and the fourth casing 62 can surround the The two hinges 66 are opened and closed. After the third casing 61 and the fourth casing 62 are closed, the plug-in parts of the third casing 61 and the fourth casing 62 are plugged and locked with each other, so as to ensure that the third casing 61 and the fourth casing 62 are connected to each other. The connection state of the housing 62; the second fixing groove 63 has a plurality of mutually matched sliding-limiting parts to ensure that the second operating part 60 and the second operating wire 22 will not slide relative to each other after being clamped.

It should be understood by those skilled in the art that the first operation part 50 also has the same plug-in part and slip-limiting part as the second operation part 60 .

Preferably, the second operation part 60 has a larger size than the first operation part 50 .

According to FIGS. 8-10 , preferably, a side surface of the first operating portion 50 has a first limiting portion 57 ; a side surface of the second operating portion 60 has a second limiting portion 67 , and the second limiting portion 67 has a plurality of limiting portions. position; the first limiting portion 57 can be detachably connected to a plurality of limiting positions of the second limiting portion 67 .

Preferably, the first limiting portion 57 has a rack locking protrusion 571; the second limiting portion 67 has a rack locking groove 671, the rack locking groove 671 can define a plurality of limit positions; the rack locking protrusion 571 can be inserted into the tooth Multiple limit positions in the strip card slot 671 .

As another preferred embodiment, the second limiting portion 67 is a card slot, which can define multiple limiting positions; the first limiting portion 57 is a snap protrusion; the snap protrusion can be inserted into a plurality of limit positions in the card slot. Position, the two rely on the interference fit to engage with each other.

Preferably, the first operation part 50 and/or the second operation part 60 include scale marks, so as to facilitate the doctor to record and identify the current relative positions of the two. Those skilled in the art should understand that the scale can reflect the state of the expandable stent 10 to a certain extent.

Preferably, the first operating portion 50 and/or the second operating portion 60 have a first anti-slip gripping portion 58 and a second anti-slip gripping portion 68, respectively.

At a certain time point in the implementation of the interventional operation, the doctor may choose to introduce the auxiliary components of the fourth embodiment. 60 is clamped on the first operating wire 21 and the second operating wire 22 respectively, as shown in FIG. 11 , and the initial relative position is recorded, and then the operation method in Example 1 is continued.

Example 5

This Embodiment 5 provides a preferred adjustable stand-type bolt retrieval device, which provides a locking aid according to FIGS. 12-13 . This solution is especially suitable for the case where both the first operating wire 21 and the second operating wire 22 of the adjustable stent-type thrombectomy device are non-diameter-reducing wires.

The locking auxiliary component includes: a third operating part 70 ; the adjustable bracket-type third operating part 70 includes a fifth housing 71 and a sixth housing sleeved on the adjustable bracket-type first operating wire 21 and the second operating wire 22 In the body 72 , the adjustable bracket-type fifth housing 71 can rotate relative to the adjustable bracket-type sixth housing 72 to limit the relative movement of the adjustable bracket-type first operating wire 21 and the second operating wire 22 .

Preferably, one end of the sixth shell 72 has a plurality of elastic cards with threads, and the fifth shell 71 is rotatably sleeved on this end of the sixth shell 72. When the fifth shell 71 is relative to the sixth shell 71 When the casing 72 rotates clockwise or counterclockwise, the fifth casing 71 gradually approaches the sixth casing 72 and compresses a plurality of elastic cards, and the plurality of elastic cards all shrink toward the center and compress the first operating wire 21 and the second operating wire 21 Wire 22, so that the relative sliding of the two is restricted, and the locking function is realized.

The embodiments of the present invention have been described above in conjunction with the accompanying drawings, but the present invention is not limited to the above-mentioned specific embodiments, which are merely illustrative rather than restrictive. Under the inspiration of the present invention, without departing from the spirit of the present invention and the scope protected by the claims, many forms can be made, which all belong to the protection of the present invention.

Claims

An adjustable stent-type thrombectomy device, characterized in that it comprises:

An expandable stent comprising a proximal end and a distal end, the expandable stent being capable of radial expansion or radial collapse when the distance between the proximal end and the distal end is compressed or stretched;

a sleeve, the distal end of the sleeve is connected to the proximal end of the expandable stent, the proximal end of the sleeve is provided with a connecting piece; the connecting piece has a fixing point and a perforation;

a first operating wire, which passes through the perforation and can slide in the sleeve, the first operating wire is fixedly connected with the distal end of the expandable stent;

The second operating wire is fixedly connected to the fixing point of the connecting piece;

The proximal ends of the first operation wire and the second operation wire are used for external hand-held operation.
The adjustable stent-type thrombectomy device according to claim 1, wherein the expandable stent comprises a metal braided mesh stent or a laser engraved mesh stent.
The adjustable stent-type thrombectomy device according to claim 1, wherein the expandable stent converges on the distal end, and/or the expandable stent converges on the proximal end.
The adjustable stent-type thrombectomy device according to claim 1, wherein the second operating wire has a higher mechanical strength than the first operating wire.
The adjustable stent-type thrombectomy device of claim 4, wherein the second operating wire has a larger diameter than the first operating wire.
The adjustable stent-type thrombectomy device according to claim 4, wherein the second operation wire adopts a material with higher mechanical strength than the first operation wire.
The adjustable stent-type thrombectomy device according to claim 1, wherein the distal end and the proximal end of the first operating wire and/or the second operating wire have different diameters.
The adjustable stent-type thrombectomy device according to claim 7, wherein the distal end of the first operating wire and/or the second operating wire has a smaller diameter than the proximal end.
The adjustable stent-type thrombectomy device according to claim 1, wherein the proximal end portion of the first operating wire and/or the second operating wire has a non-slip surface;

And/or, the distal portion section of the first and/or second manipulation wire has a smooth surface.
The adjustable stand-type bolt removal device according to claim 9, wherein the non-slip surface is an anti-slip coating, or an anti-slip scribe, or an anti-slip glue layer;

And/or, the smooth surface is a hydrophilic coating.
The adjustable stent-type thrombectomy device according to claim 1, wherein the proximal end portion of the first operating wire and/or the second operating wire has a color mark.
The adjustable stent-type thrombectomy device according to claim 11, wherein the proximal end portions of the first operating wire and the second operating wire have different color markings.
The adjustable stent-type thrombectomy device according to claim 12, wherein the first operating wire and the second operating wire respectively have a plurality of different color marks.
The adjustable stent-type thrombectomy device according to any one of claims 1 to 13, wherein the expandable stent, and/or the first operating wire, and/or the second operating wire, are made of nickel titanium Alloy material or developable alloy material.
The adjustable stent-type thrombectomy device according to any one of claims 1-13, wherein the distal end of the expandable stent has a developing spring.
The adjustable stent-type thrombectomy device according to any one of claims 1-13, wherein the distal end of the expandable stent has a first developing ring; and/or, the proximal end of the expandable stent has a first imaging ring; The end has a second developing ring.
The adjustable stent-type thrombectomy device according to any one of claims 1-13, further comprising a guide tube capable of accommodating the expandable stent in a collapsed state therein.
The adjustable stent-type thrombectomy device according to claim 17, wherein the distal end of the catheter has a third developing ring.
The adjustable stent-type thrombectomy device according to any one of claims 1-18, further comprising:

a first operating portion, detachably fixed to the first operating wire;

The second operation part is detachably fixed to the second operation wire.
The adjustable stand-type bolt removal device according to claim 19, wherein the first operation part comprises a first casing and a second casing that are oppositely disposed and separable; the first casing and the second casing are oppositely disposed. A first fixing groove for accommodating and fixing the first operating wire is defined between the two housings;

The second operation part includes a third casing and a fourth casing that are oppositely arranged and separable; a second casing for accommodating and fixing the second operating wire is defined between the third casing and the fourth casing. Fixed slot.
The adjustable stand-type bolt removal device according to claim 19, wherein the second operating portion has a larger size than the first operating portion.
The adjustable stand-type bolt removal device according to claim 19, wherein a side surface of the first operating portion has a first limiting portion; a side surface of the second operating portion has a second limiting portion, The second limiting portion has multiple limiting positions; the first limiting portion can be detachably connected with the multiple limiting positions of the second limiting portion.
The adjustable bracket-type bolt removal device according to claim 22, wherein the first limiting portion is a rack locking protrusion; the second limiting portion is a rack locking groove, and the rack locking The slot can define a plurality of limit positions; the rack locking protrusion can be inserted into the plurality of limit positions in the rack locking groove.
The adjustable bracket-type bolt removal device according to claim 22, wherein the second limiting portion is a slot, and the slot can define a plurality of limiting positions; the first limiting portion is a A card protrusion; the card protrusion can be inserted into a plurality of limit positions in the card slot.
The adjustable stand-type thrombus removal device according to claim 19, wherein the first operation part and/or the second operation part includes a scale mark.
The adjustable stand-type bolt removal device according to claim 19, wherein the first operation part and/or the second operation part has a non-slip gripping part.
The adjustable stand-type thrombus removal device according to any one of claims 1-18, characterized in that, further comprising: a third operation part;

The third operating part includes a fifth housing and a sixth housing sleeved on the first operating wire and the second operating wire, and the fifth housing can rotate relative to the sixth housing to The relative movement of the first operating wire and the second operating wire is restricted.