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WO2022247175A1 - Mécanisme de poussée, et dispositif d'injection automatique l'utilisant et méthode d'utilisation associée - Google Patents

Mécanisme de poussée, et dispositif d'injection automatique l'utilisant et méthode d'utilisation associée Download PDF

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Publication number
WO2022247175A1
WO2022247175A1 PCT/CN2021/132032 CN2021132032W WO2022247175A1 WO 2022247175 A1 WO2022247175 A1 WO 2022247175A1 CN 2021132032 W CN2021132032 W CN 2021132032W WO 2022247175 A1 WO2022247175 A1 WO 2022247175A1
Authority
WO
WIPO (PCT)
Prior art keywords
sleeve
sounding
self
push rod
locking
Prior art date
Application number
PCT/CN2021/132032
Other languages
English (en)
Chinese (zh)
Inventor
王佩儿
Original Assignee
宁波易舒医疗科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 宁波易舒医疗科技有限公司 filed Critical 宁波易舒医疗科技有限公司
Publication of WO2022247175A1 publication Critical patent/WO2022247175A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3257—Semi-automatic sleeve extension, i.e. in which triggering of the sleeve extension requires a deliberate action by the user, e.g. manual release of spring-biased extension means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback

Definitions

  • the present invention relates to a new type of drug delivery device for self-management of diseases by patients, more specifically, it relates to a thrust mechanism with automatic feedback function, an automatic injection device using the thrust mechanism with automatic feedback function, and the automatic injection device usage method.
  • the invention patent with publication number CN101678168A disclosed an injection device on March 24, 210, comprising: a housing; The end of the rear end of the injection device is placed together on the patient's injection site; the injection needle, which in the piercing position protrudes beyond the end of the rear end of the injection device and can move back into the interior of the injection device a switching cam, which is axially fixedly arranged relative to the injection needle and engages in the locking window in the piercing position for preventing a retraction movement of the injection needle into the interior of the injection device; wherein , the switching cam can be moved out of engagement with the locking window by means of the actuating sleeve, so that the injection needle is released for a retraction movement.
  • the stopping elements used for vocal feedback are continuously distributed, and they are always vocal from the beginning of the injection to the end of the injection, and there is no obvious distinction, which is likely to cause confusion for the patient's hearing and identification, and the injection status cannot be accurately identified.
  • the auditory feedback provided by the existing automatic injection device during the working process lacks clear identifiability, and it is difficult to identify the start and end states of injection.
  • the present invention provides a thrust mechanism with automatic feedback function,
  • the automatic injection device using the thrust mechanism and its use method have simple structure, low cost, are more suitable for commercial production, are easy to use, have clear and obvious auditory feedback, and are easy to identify the injection state.
  • the technical solution of the present invention is: a thrust mechanism with automatic feedback function, including a push rod, a reciprocating sleeve, a return spring and a bottom cover, the return spring is sleeved outside the reciprocating sleeve, and an injection
  • the spring and the reciprocating sleeve can lock the push rod and release the push rod before the push rod is started to advance.
  • This thrust mechanism also includes a sounding guide assembly.
  • the push rod, the reciprocating sleeve and the sounding guide assembly are coaxially sliding and nested. When the propulsion begins and ends, the sound guide assembly and the push rod act to generate the start prompt sound and the end prompt sound respectively.
  • This thrust mechanism When the thrust mechanism is working, slide the reciprocating sleeve backward to release the push rod, at this time the push rod can be pushed forward to push other actuators to work. During the process from unlocking and starting to bottoming out of the push rod, the push rod can interact with the sounding guide assembly at the beginning and end to make sound. Through sound feedback, the user is reminded of the stage of the working process of the mechanism, and the auditory signal is clear, clear and concise. Indicates the start and end status of the thrust mechanism.
  • This thrust mechanism only integrates main functions such as release, propulsion, and reminder through a simple nested combination of a series of components. It can be used as the core mechanism for some devices that implement more specific operations, such as automatic injection devices, which can greatly simplify the device. The structure is beneficial to the device to be more compact, portable, easy to manufacture and convenient to use.
  • the sounding guide assembly is connected in the reciprocating sleeve, and the push rod is connected in the sounding guide assembly.
  • the sounding guide assembly includes a fixed guide sleeve, a rotating power element and a sounding ring, and a fixed guiding sleeve, a rotating power element and a sounding ring.
  • the rings are coaxially nested, and the fixed guide sleeve is movably connected with the sounding ring through the rotating power element.
  • the sounding ring can rotate around the axis of the fixed guide sleeve, and the rotating power element provides kinetic energy for the rotation of the sounding ring.
  • the fixed guide sleeve can guide the push rod to move and change posture according to the set path.
  • the sounding ring has the function of interacting with the push rod to make a sound and locking the reciprocating sleeve after the reciprocating sleeve reciprocates once. Therefore, the sounding guide assembly has functions such as sounding, self-locking, state switching, and injection distance limit of the push rod. It integrates the main performance-related features of the product into one part, greatly reducing the parts required for product composition. Contribute to the improvement of product stability.
  • a propulsion guide groove is provided in the fixed guide sleeve along the axial direction
  • a pair of sound-producing flying wings is provided at the rear end of the push rod
  • a slant slot capable of accommodating the sound-producing flying wings is provided at the rear end of the groove wall on one side of the propulsion guide groove.
  • the front end of the inclined surface card slot is provided with a guide groove slope facing the propulsion guide groove, and the sounding flying wing is slidably connected in the propulsion guiding groove, and the sounding flying wing is blocked by the reciprocating sleeve in the inclined plane carding groove before the push rod starts to advance.
  • the sounding flying wing In the initial state, the sounding flying wing is blocked by the reciprocating sleeve and is restricted in the slot on the inclined plane, unable to enter the propulsion guide groove and slide along the propulsion guide groove, thereby locking the push rod and shielding the axial propulsion function of the push rod.
  • the thrust mechanism When the thrust mechanism is not activated; when the reciprocating sleeve retreats, the lock on the push rod can be released, and the injection spring provides power for the push rod to advance axially forward. It also produces a reaction force on the sounding flying wing.
  • the lateral component of the reaction force can push the sounding flying wing to rotate toward the advancing guiding groove, so that the sounding flying wing enters the advancing guiding groove, and then moves along the Push the guide groove to slide, and the push rod starts to advance axially forward.
  • the sounding flying wing hits the side wall of the propulsion guide groove, generating an initial prompt sound.
  • the rear end of the reciprocating sleeve is provided with an axial cantilever
  • the inner surface of the free end of the axial cantilever is provided with an inner stopper
  • the outer wall of the fixed guide sleeve is provided with a
  • the strip window in the initial state, the inner block is embedded in the strip window and the propulsion guide groove and is opposed to the sounding flying wing.
  • the initial state that is, when the thrust mechanism has not been activated, due to the blockage of the inner stop block, the sound-emitting flying wing is restricted in the slot on the inclined plane and cannot slide into the propulsion guide slot, so as to ensure that the position of the push rod is kept fixed, and the push rod is realized.
  • the lever activates propulsion to counteract the blocking action of the sleeve against the sounding flying wing.
  • the front end of the sound-emitting flying wing is provided with a flying wing slope that can fit and fit with the slope of the guide groove.
  • the face-to-face bonding between the sounding flying wing and the inclined surface of the guide groove can ensure the continuous and stable interaction force between the sounding flying wing and the inclined surface of the guiding groove.
  • the inner wall of the sounding ring is provided with an inner flying wing
  • the outer peripheral surface of the push rod is provided with a limit chute
  • the front end of the groove wall on one side of the limit chute is provided with a sounding groove that can accommodate the inner flying wing, and the push rod is pushed to the limit.
  • the front inner flying wing is adapted to be embedded in the limit chute, and the rotating power element is in a tensioned state at this time. When the push rod is pushed to the limit, the inner flying wing enters the sounding groove.
  • the inner flying wing Before the push rod is pushed to the limit, the inner flying wing is constrained by the limit chute to maintain a stable posture; when the push rod is pushed to the limit, the inner flying wing reaches the position of the sounding groove, and the sounding ring rotates under the action of the elastic force. The inner flying wing turns into the sounding groove, and hits the side wall of the sounding groove to make a sound, forming a termination prompt sound, reminding the user that the pushing of the push rod is completed.
  • the reciprocating sleeve, the fixed guide sleeve and the sounding ring are all integrally formed injection molded parts.
  • the axial cantilever on the reciprocating sleeve needs to have elastic reset ability, and injection molding method should be used.
  • the natural properties of plastic can endow the above structure with elastic reset ability.
  • An automatic injection device using a thrust mechanism with an automatic feedback function including a head-end protective cap, a safety sleeve, a shell assembly composed of a shell and a protective shell, and a prefilled syringe, and also includes a self-locking structure, which can After the safety sleeve reciprocates once, the safety sleeve is locked, the prefilled syringe and the thrust mechanism with automatic feedback function are arranged in the cavity of the housing assembly, and the output end of the thrust mechanism is connected with the prefilled syringe.
  • the present invention provides a safe automatic injection device in order to realize self-administration of patients in home care/first aid in the field and reduce unnecessary medical expenses.
  • the device is easy to use, small in size and easy to carry. Compliance, manual needle insertion and automatic injection, stable needle depth, needle shielding before and after use, eliminating the fear of patients.
  • the self-locking structure is set on the thrust mechanism with automatic feedback function
  • the self-locking structure includes an anti-retreat stopper set on the sounding ring, and is set at the front end of the reciprocating sleeve and can be placed on the reciprocating sleeve.
  • a self-locking cantilever that is stopped by an anti-backstop after reciprocating once. Before the push rod is pushed to the limit, the anti-retreat stopper is not on the moving path of the self-locking cantilever, and the reciprocating sleeve can overlap with the sounding ring without hindrance; The barrel resets, the sounding ring rotates, and the anti-retraction block is transferred to the moving path of the self-locking cantilever.
  • the sounding guide assembly locks the reciprocating sleeve, realizing the one-time use of the automatic injection device, and meeting specific application fields safety requirements.
  • a slope surface is provided on the rear end surface of the anti-retraction block, and the slope surface faces the end where the bottom cover is located.
  • the front end surface of the anti-retraction stopper is a sloped surface of an inner buckle barb.
  • the slope of the inner buckle barb decomposes to form a lateral force that presses the self-locking cantilever downward, and the self-locking cantilever cannot expand Therefore, the self-locking cantilever cannot climb over the anti-retreat block, so as to reliably realize the self-locking after the reciprocating sleeve reciprocates once.
  • the front end surface of the anti-retraction block is a plane perpendicular to the axis of the sounding ring.
  • the self-locking cantilever will not generate lateral component force to expand the self-locking cantilever when it touches, and it can also prevent the self-locking cantilever from overturning the anti-retreat stopper, thereby realizing self-locking after the reciprocating sleeve reciprocates once.
  • the self-locking structure is provided on the housing assembly, and the self-locking structure includes a safety sleeve self-locking cantilever provided on the safety sleeve and a lock block provided on the shell, and the safety sleeve
  • the cylinder self-locking cantilever is provided with a self-locking convex point
  • the lock block is provided with a starting side wall and a reset side wall intersecting at the rear end of the lock block
  • a V-shaped groove is provided at the front end of the lock block.
  • the present invention can also realize the self-locking of the automatic injection device through the interlocking between the safety sleeve and the shell.
  • the self-locking protrusions of the safety sleeve can cling to the starting side wall and move without hindrance during the pressure retreat process of the safety sleeve, and the self-locking protrusions can cling to the safety sleeve during the reset process Start the barrier-free movement of the side wall.
  • the self-locking convex point falls into the V-shaped groove and is locked, thereby blocking the path of the safety sleeve to retreat again, and completing the self-locking of the automatic injection device.
  • the axial drive mechanism with dual visual feedback has many parts and small size, and its structure is extremely compact. Sometimes, if too many functional structures are given to it, it will cause certain manufacturing difficulties; while the size of the shell component parts is relatively simple in structure , The size is large, there is more space to arrange the functional structure more conveniently, and at the same time, it will not increase the number of parts.
  • the prefilled syringe includes a needle shield, a glass cylinder with a needle, an injection needle and a plunger.
  • the head-end protection cap is provided with claws, and the claws are stuck in the gap between the needle shield and the glass cylinder with needles.
  • the head-end protective cap is installed on the front end of the pre-filled syringe through the claw, which can effectively prevent the safety sleeve from being triggered and is easy to disassemble.
  • a sliding limit structure is provided between the safety sleeve and the housing. Under the action of the return spring, the safety sleeve can be pushed by the reciprocating sleeve to telescopically slide in the housing, and the sliding limit structure can limit the position of the safety sleeve to prevent the safety sleeve from detaching from the housing.
  • the housing is provided with a liquid medicine window.
  • the liquid medicine window is used to observe the remaining liquid medicine and the position of the piston to understand the injection process.
  • the working method of the described automatic injection device comprises the following steps:
  • Step 1 Pull out the head-end protective cap, and take the needle protective cap out of the prefilled syringe;
  • Step 2 Put the safety sleeve vertically on the skin surface of the injection site, press down on the shell, the safety sleeve shrinks back to the inside of the shell, and at the same time drives the reciprocating sleeve back and moves to the rear end, while the reciprocating sleeve moves Compression return spring;
  • Step 3 With the movement of the reciprocating sleeve, when the inner stopper crosses the top surface of the sounding flying wing, the inner stopper no longer blocks the sounding flying wing, and the push rod slides along the slope of the guide groove under the action of the energy released by the injection spring Enter the injection guide groove, under the action of inertia, the sounding flying wing hits the side wall of the injection guide groove, and an initial prompt sound is issued;
  • Step 4 The push rod starts to move from the rear end to the front end under the action of the injection spring, driving the piston forward to inject the liquid medicine;
  • Step 5 With the liquid medicine injection completed, push the push rod to the limit, and the inner sounding flying wing breaks away from the limit chute and enters the sounding groove. The limit chute no longer restricts the rotation of the inner sounding flying wing. Next, the sounding ring starts to rotate, and the inner sounding flying wing hits the side wall of the sounding groove, giving a termination prompt sound;
  • Step 6 After the user hears the prompt sound of injection termination, remove the safety sleeve from the surface skin of the injection site, move the rear end of the reciprocating sleeve to the front end, and drive the safety sleeve back to the initial position at the same time, and continue to shield the injection needle ;
  • Step 7 The automatic injection device completes self-locking, and the safety sleeve is prevented from retreating again.
  • This product has the function of automatic injection, and at the same time has the function of sound feedback and visual feedback during the injection process, which is convenient for patients to grasp the injection status, reduces the fear of injection, and is suitable for a wide range of people.
  • the product has fewer parts and a compact structure to achieve miniaturization, easy to carry, simple steps to use, easy for users to grasp, and good product compliance.
  • the product is safe and reliable. Patients will not see the needle tip during use. After use, the product is self-locking and cannot be used again. At the same time, the needle tip is covered to prevent damage caused by accidental touch.
  • the product can realize modular design, which is convenient for sales and transportation, and reduces production cost waste.
  • the product is composed of a mechanical structure, the reliability of the parts is high, the environmental change has little impact on its performance, and it is not easy to age.
  • each buckle of the product is firm to avoid deformation and failure of weak parts caused by stress concentration. Description of drawings
  • Fig. 1 is a kind of overall structure schematic diagram of the present invention
  • Fig. 2 is a kind of part explosion diagram of the present invention
  • Fig. 3 is a kind of structural representation of prefilled syringe among the present invention.
  • Fig. 4 is a schematic structural view of the sound guide assembly in the present invention.
  • Fig. 5 a is a kind of overall longitudinal sectional schematic view of the present invention.
  • Fig. 5b is a schematic diagram of the overall longitudinal section after the position shown in Fig. 5a is rotated by 90°;
  • Fig. 6a is a schematic structural view of a safety sleeve in the present invention.
  • Fig. 6b is a cross-sectional view of the safety sleeve in the present invention.
  • Fig. 7a is a schematic structural view of the shell in the present invention.
  • Fig. 7b is a partial structural schematic diagram of the shell in the present invention.
  • Figure 8a is a schematic structural view of the head-end protective cap in the present invention.
  • Fig. 8b is a cross-sectional view of the head-end protective cap in the present invention.
  • Fig. 9 is a schematic structural view of the present invention after pulling out the head-end protective cap
  • Fig. 10a is a schematic diagram of partial cooperation of the present invention when it is in an unactivated state
  • Figure 10b is a schematic structural view of the fixed guide sleeve in the present invention.
  • Figure 10c is a cross-sectional view of the fixed guide sleeve in the present invention.
  • Figure 10d is a schematic structural view of the push rod in the present invention.
  • Figure 10e is a front view of the push rod in the present invention.
  • Figure 10f is a side view of the push rod in the present invention.
  • Fig. 11a is the overall longitudinal sectional view when the present invention is activated
  • Figure 11b is a schematic diagram of partial cooperation when the present invention is activated
  • Figure 12a is a schematic diagram of a state during the injection process of the present invention.
  • Figure 12b is a schematic diagram of the partial cooperation of the present invention during the injection process
  • Fig. 13a is a schematic diagram of the sounding principle of the sounding ring at the end of the injection according to the present invention.
  • Figure 13b is a schematic diagram of the overall longitudinal section of the present invention at the end of the injection;
  • Fig. 14 is an overall longitudinal sectional schematic diagram of the present invention entering the self-locking state after the injection is completed;
  • Figure 15 is a schematic structural view of a reciprocating sleeve in the present invention.
  • Fig. 16 is a structural schematic diagram of the sounding ring in the present invention.
  • Fig. 17 is another structural schematic view of the safety sleeve in the present invention.
  • Figure 18a is a schematic structural view of the shell in the present invention.
  • Figure 18b is a schematic diagram of the position of the lock block on the shell in the present invention.
  • Figure 19a is a schematic diagram of the position of the safety sleeve self-locking cantilever when the automatic injection device is not activated in the present invention
  • Figure 19b is a schematic diagram of the position of the self-locking cantilever of the safety sleeve during the injection process of the automatic injection device in the present invention
  • Figure 19c is a schematic diagram of the position of the safety sleeve self-locking cantilever during the reset process of the safety sleeve in the present invention
  • Fig. 19d is a schematic diagram of the position of the safety sleeve self-locking cantilever when the automatic injection device is self-locking in the present invention.
  • an automatic injection device includes a head-end protective cap 1, a safety sleeve 3, a housing 2, a protective shell 4, a prefilled syringe 5, a push rod 6, a reciprocating sleeve 7, a reset
  • the spring 8, the sounding guide assembly 9 and the bottom cover 11, the injection spring 10 is arranged between the push rod 6 and the bottom cover 11, the head end protective cap 1, the safety sleeve 3, the shell 2 and the protective shell 4 constitute the shell assembly, the push rod 6.
  • the reciprocating sleeve 7, the return spring 8, the sounding guide assembly 9 and the bottom cover 11 form a thrust mechanism with an automatic feedback function.
  • the front end of the push rod 6, that is, the end facing the prefilled syringe 5 is the output end of the thrust mechanism , the prefilled syringe 5 and the thrust mechanism are located in the cavity of the housing assembly.
  • Safety sleeve 3, shell 2, protective shell 4, prefilled syringe 5, push rod 6, reciprocating sleeve 7, return spring 8, sounding guide assembly 9 and injection spring 10 are all coaxially nested together, and the condom
  • the barrel 3 is slidably embedded in the front end of the shell 2 and behind the head-end protective cap 1.
  • the pre-filled syringe 5, push rod 6, reciprocating sleeve 7 and sound-generating guide assembly 9 are arranged on the head-end protective cap 1, the shell 2 and the bottom.
  • the protective shell 4 is embedded in the outer shell 2 and socketed outside the prefilled syringe 5, the return spring 8 is socketed outside the reciprocating sleeve 7, and the reciprocating sleeve 7 can be pushed forward by the push rod 6
  • the front locking push rod 6 can be moved backward to release the push rod 6, the push rod 6, the reciprocating sleeve 7 and the sounding guide assembly 9 are coaxially slid and nested, and the sounding guide assembly 9 can lock the reciprocating sleeve 7 after the reciprocating sleeve 7 reciprocates once
  • the sound guide assembly 9 interacts with the push rod 6 to generate a start prompt sound and an end prompt sound respectively.
  • the sounding guide assembly 9 is connected in the reciprocating sleeve 7, and the push rod 6 is connected in the sounding guide assembly 9.
  • the sounding guide assembly 9 includes a fixed guide sleeve 91, a rotating power element 92 and a sound ring 93.
  • the fixed guide sleeve 91 1.
  • the rotating power element 92 and the sounding ring 93 are coaxially nested, and the fixed guide sleeve 91 and the sounding ring 93 are movably connected through the rotating power element 92 .
  • the rotating power element 92 is a torsion spring, and the rotating power element 92 provides kinetic energy for the rotation of the sounding ring 93 around the fixed guiding sleeve 91 .
  • the rear end of the fixed guiding sleeve 91 is provided with a pair of buckles 9101 for matching with the buckle grooves on the bottom cover 11 .
  • a propulsion guide groove 9103 is provided in the fixed guide sleeve 91 along the axial direction, a pair of sounding flying wings 62 are provided at the rear end of the push rod 6 , and an inclined surface capable of accommodating the sounding flying wings 62 is provided at the rear end of the groove wall on one side of the advancing guide groove 9103 Slot 9104, Slope
  • the front end of the slot 9104 is provided with a guide groove slope 9105 facing the propulsion guide groove 9103, and the sounding flying wing 62 is slidably connected in the propulsion guide groove 9103.
  • the rear end of the reciprocating sleeve 7 is provided with an axial cantilever 71, the inner surface of the free end of the axial cantilever 71 is provided with an inner stopper 72, and the outer wall of the fixed guide sleeve 91 is provided with an inner cavity that penetrates to the fixed guide sleeve 91 and is compatible with the propulsion guide.
  • the strip window 9102 corresponding to the position of the groove 9103, in the initial state, that is, before the push rod 6 starts to advance, the inner stopper 72 is embedded in the strip window 9102 and the advancing guide groove 9103 and resists the sounding flying wing 62, so that the sounding flying wing 62 is blocked in the inclined plane slot 9104.
  • the front end of the sound-emitting flying wing 62 is provided with a flying wing slope 63 that can be fitted to the guide groove slope 9105 .
  • An inner flying wing 931 is integrally formed on the inner wall of the sounding ring 93, and the outer peripheral surface of the push rod 6 is provided with a limiting chute 64, and the rear end of the side wall of the limiting chute 64 is provided with a sounding groove capable of accommodating the inner flying wing 931 65, the width of the sounding groove 65 is greater than the limit chute 64, and the inner flying wing 931 is adapted to be embedded in the limit chute 64 before the push rod 6 is advanced to the limit, and at this time the rotating power element 92 is in tension and energy storage state, when the push rod 6 was advanced to the limit, the inner flying wing 931 entered the sounding groove 65.
  • the sounding ring 93 is provided with an anti-retreat block 9302, and the front end of the reciprocating sleeve 7 is provided with a self-locking cantilever 73 that can be blocked by the anti-retreat block 9302 after the reciprocating sleeve 7 reciprocates once.
  • There is a slope surface 933 the slope surface 933 faces the end where the bottom cover 11 is located, and the front end surface 924 of the anti-retraction stopper is an inclined surface of an inner buckle barb.
  • the prefilled syringe 5 includes a needle protective cap 51, a glass cylinder 52 with a needle, an injection needle 521 and a piston 54.
  • the glass cylinder 52 with a needle contains a liquid medicine 53, and the head-end protective cap 1 is provided with a claw 101. 101 is stuck in the gap between the needle caps 51 and 52, the piston 54 is slidably embedded in the needled glass cylinder 52 and forms a dynamic seal with the inner wall of the needled glass cylinder 52, and the push rod 6 is inserted into the needled glass cylinder 52 to drive the piston 54.
  • the safety sleeve 3 includes a sleeve head and a pair of tile-shaped long cantilevers connected to the rear end of the sleeve head. The sleeve head and the tile-shaped long cantilever are integrally formed. A sliding limit structure is provided between the safety sleeve 3 and the casing 2.
  • the sliding limit structure includes clamping arms 31 integrally formed on both sides of the tile-shaped long cantilever and an inner wall boss 22 fixed on the inner wall of the housing 2.
  • the tile-shaped long cantilever is always in contact with a convex ring end surface on the reciprocating sleeve 7 .
  • the housing 2 is provided with a liquid medicine viewing window 21 and a buckle 23 located at the rear end of the housing 2 .
  • the bottom cover 11 is provided with a buckle groove 111 adapted to the buckle 23 .
  • the reciprocating sleeve 7, the fixed guiding sleeve 91 and the sounding ring 93 are all integrally formed injection moldings.
  • the reciprocating sleeve 7 When assembling, the reciprocating sleeve 7 is set outside the sounding guide assembly 9, the return spring 8 is set between the outer wall of the reciprocating sleeve and the bottom cover 11, and the bottom cover 11 and the fixed guide sleeve 91 are fixedly connected together by buckling, etc.
  • the injection spring 10 is placed in the inner hole 61 of the push rod 6, with one end abutting against the front end face of the inner hole, and the other end abutting against the end face of the bottom cover 11, and the push rod 6 and the injection spring 10 are pressed into the inner hole of the sound-generating guide assembly 9 Inside, the bottom cover 11, the injection spring 10, the sounding guide assembly 9, the return spring 8, the reciprocating sleeve 7, and the push rod 6 are connected into one body through the above methods.
  • the safety sleeve 3 is inserted into the inner hole of the housing 2. During the loading process, the locking arm 31 of the safety sleeve 3 encounters the obstruction of the inner wall boss 22 of the housing 2 and retracts.
  • the locking arm 31 Open and reset, the cantilever is embedded in the chute between the bosses. At this time, the movement of the safety sleeve 3 to the front is limited by the bosses. The rear end surface of the safety sleeve 3 is in contact with the front surface of the reciprocating sleeve 7. At this time, the full sleeve 3 directions The movement stroke of the front end is determined by the movement stroke of the reciprocating sleeve 7.
  • the head-end protective cap 1 is coaxially installed on the safety sleeve 3, and its internal convex point 102 is stuck on the annular lip 32 of the safety sleeve 3, pre-filled
  • the syringe 5 is inserted into the inner hole of the protective sleeve 4, and then inserted into the inner hole of the housing together, and is also located in the inner hole of the safety sleeve 3.
  • the hook claw 101 of the head-end protective cap 1 cantileverly inserts into the needle protective cap 51 In the assembly gap with the glass cylinder 52 with a needle, insert the assembled automatic injection part into the casing 2 along the axis of the casing, and the buckle 23 at the rear end of the casing 2 is buckled into the slot 111 of the bottom cover 11, so far the whole product is assembled as a whole .
  • the whole product is in an untriggered state, and the inner block 72 of the reciprocating sleeve 7 is embedded in the advancing guide groove 9103 through the strip window 9102 on the advancing guiding groove 9103 of the fixed guiding sleeve 91; 62 falls into the inclined plane slot 9104 at the rear end of the fixed guide sleeve 91, and the push guide slot 9102 communicates with the inclined plane slot 9104.
  • the injection spring 10 is in the state of energy storage, and a thrust from the rear end to the front end is applied to the push rod 6 , under the action of the thrust, the flying wing slope 63 at the front end of the sounding flying wing 62 is close to the guide groove slope 9105 of the slope card slot 9104, and the slope has a decomposing effect on the thrust, causing the sounding flying wing 62 to slide down along the guide groove slope 9105 and enter the propulsion guide
  • the groove 9103 tends, but due to the existence of the inner stopper 72, the sound-emitting flying wing 62 is prevented from sliding into the advancing guide groove 9103.
  • the working method of this automatic injection device comprises the following steps:
  • Step 1 Pull out the head-end protective cap 1, and take the needle protective cap 51 out of the prefilled syringe 5, because the claw 101 on the head-end protective cap is hooked into the needle protective cap on the prefilled syringe 5 51 and the glass cylinder 52 with needle, so when the head-end protective cap 1 is pulled out, the needle protective cap 51 can be taken out. At this time, the injection needle 521 is exposed. Due to the shielding effect of the safety sleeve 3, the user is more ugly to the injection needle, thereby reducing the fear before use;
  • Step 2 Stick the safety sleeve 3 vertically on the skin surface of the injection site, press down on the outer shell 2, the safety sleeve 3 shrinks inwards to the inside of the outer shell 2, and at the same time drives the reciprocating sleeve 7 to move back, move to the rear end, and reciprocate
  • the return spring 8 is compressed while the sleeve 7 moves;
  • Step 3 With the movement of the reciprocating sleeve 7, when the inner stopper 72 crosses the top surface of the sounding flying wing 62, the inner stopper 72 no longer blocks the sounding flying wing 62, and the push rod 6 releases energy from the injection spring 10. Under the action, slide into the injection guide groove 9103 along the guide groove slope 9105, and under the action of inertia, the sounding flying wing 63 hits the side wall of the injection guide groove 9103, making a "click" impact sound, which becomes the initial prompt sound, prompting the user to inject start;
  • Step 4 The push rod 6 starts to move from the rear end to the front end under the action of the injection spring 10, and drives the piston 54 forward to inject the medicinal solution 53.
  • the patient can observe the position of the piston 54 through the observation window 21 and clearly understand the current position. Injection status;
  • Step 5 After the liquid medicine 53 is injected, the push rod 6 is pushed to the limit, the inner sounding flying wing 9301 breaks away from the limiting chute 64 and enters the sounding groove 65, and the limiting chute 64 no longer rotates to the inner sounding flying wing 9301 Limitation, driven by the rotating power element 92, the sounding ring 93 starts to rotate, and the inner sounding flying wing 9301 hits the side wall of the sounding groove 65, making a "click" sound, which becomes a termination prompt sound, reminding the user that the injection is completed;
  • Step 6 After the user hears the prompt sound of injection termination, remove the safety sleeve 3 from the surface skin of the injection site, move the rear end of the reciprocating sleeve 7 to the front for reset, and at the same time drive the safety sleeve 3 to return to the initial position, and continue to The injection needle 521 is covered, and it is still difficult for the user to observe the injection needle 521, thereby ensuring that the injection needle 521 will not be seen during the entire use process;
  • Step 7 Since the sounding ring 93 rotates at an angle when the injection is completed, the anti-retraction stopper 9302 on the sounding ring 93 is located on the movement path of the self-locking cantilever 73, and the self-locking cantilever 73 climbs over the anti-retraction when the reciprocating sleeve 7 is reset Stopper 9302, press the safety sleeve 3 again, the safety sleeve 3 will drive the reciprocating sleeve 7 to shrink back, the front end surface 924 of the anti-retraction stopper is attached to the rear end surface of the self-locking cantilever 73, because the sounding ring 93 can only move in the circumferential direction.
  • the anti-retraction block 9302 blocks the reciprocating sleeve 7 from retreating, the safety sleeve 3 and the reciprocating sleeve 7 are self-locked, and the product cannot be used again, preventing personnel from contacting the used needle tip and causing injury.
  • the tile-shaped long cantilever is provided with a hollow area, and a safety sleeve self-locking cantilever 33 is provided in the hollow area, and a self-locking protrusion 34 is provided on the safety sleeve self-locking cantilever 33, so
  • the self-locking structure is arranged on the housing assembly, and the self-locking structure includes a safety sleeve self-locking cantilever 33 arranged on the safety sleeve 2 and a lock block 24 arranged on the inner wall of the casing 3, and the lock block 24 is mounted on the casing 3.
  • the inner wall protrudes radially, and the lock block 24 is V-shaped as a whole.
  • the lock block 24 is provided with a start side wall 241 and a reset side wall 242 intersecting at the rear end of the lock block 24.
  • the start side wall 241 and the reset side wall 242 intersect to form a lock block
  • the rear sharp point 245 and the front end of the locking block 24 are provided with a V-shaped groove 243 .
  • the starting side wall 241 and the inner wall of the shell 3 opposite to it form the starting movement track 25 ; the reset side wall 242 and the inner wall of the shell 3 opposite to it form the reset moving track 26 .
  • a starting point 244 is provided at the front end of the starting side wall 241
  • a terminal point 246 is provided at the front end of the reset side wall 242 .
  • the starting point 244 and the rear sharp point 245 of the locking block are slightly deviated from the center line of the shell 3.
  • the position of the self-locking convex point 34 is lower than the starting point 244 and higher than the rear sharp point 245 of the locking block.
  • the self-locking cantilever 33 of the safety sleeve swings downward.
  • the self-locking cantilever 33 of the safety sleeve is elastically deformed, and the self-locking bump 34 falls into the starting motion track 25.
  • the self-locking bump 34 is in close contact with the starting side wall 241 under the action of the reset elastic force of the sleeve self-locking cantilever 33 .
  • the self-locking protruding point 34 moves close to the starting side wall 241 when the safety sleeve 2 is pushed back under pressure, and the self-locking protruding point 34 moves close to the starting side wall 241 during the reset process of the safety sleeve 2 .
  • step 2 stick the safety sleeve 2 vertically on the skin surface of the injection site, press down on the shell 3, the safety sleeve 2 retracts to the inside of the shell 3 at the rear end, and at the same time drives the release sleeve 7 back and moves to the rear end,
  • the release sleeve 7 moves, the return spring 6 is compressed; at the same time, the self-locking protrusion 34 is still close to the starting side wall 241 and moves toward the rear end of the automatic injection device when the safety sleeve 2 is pressed back.
  • the self-locking cantilever 33 of the safety sleeve resets, and the self-locking convex point 34 is separated from the locking block 24, and the preparation for injection is completed.
  • step 7 when the release sleeve 7 is reset, the self-locking protrusion 34 is in contact with the inclined reset side wall 242, and as the safety sleeve 2 moves to the front end, the self-locking protrusion 34 is in close contact with the reset side wall 242
  • the starting side wall 241 moves in the reset motion track 26, the self-locking cantilever 33 of the safety sleeve swings upward under the top pressure of the reset side wall 242, and the self-locking cantilever 33 of the safety sleeve is elastically deformed.
  • the self-locking protrusion 34 moves When it exceeds the position of the front end point of the reset side wall 242, the self-locking cantilever 33 of the safety sleeve resets, and the self-locking bump 34 climbs over the terminal sharp point 246 under the action of the reset elastic force of the self-locking cantilever 33 of the safety sleeve, and falls into the V-shaped groove 243 In this case, since the locking block 24 and the self-locking convex point 34 coincide at a certain distance in height, the retreat movement route of the self-locking convex point 34 is restricted by the V-shaped groove 243, and the safety sleeve 2 cannot retreat again, and the entire automatic injection device is self-locking. .
  • the front end surface 924 of the anti-retraction block is a plane perpendicular to the axis of the sounding ring 93 . All the other are with embodiment 1.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un mécanisme de poussée ayant une fonction de rétroaction automatique, un dispositif d'injection automatique utilisant le mécanisme de poussée ayant une fonction de rétroaction automatique, et une méthode d'utilisation du dispositif d'injection automatique. Le mécanisme de poussée comprend une tige de poussée (6), un manchon à va-et-vient (7), un ressort de rappel (8), et un couvercle inférieur (11), le ressort de rappel (8) étant emmanché à l'extérieur du manchon à va-et-vient (7) ; un ressort d'injection (10) est disposé entre la tige de poussée (6) et le couvercle inférieur (11) ; le manchon à va-et-vient (7) peut verrouiller la tige de poussée (6) avant que la tige de poussée (6) commence à pousser, et peut ensuite reculer pour libérer la tige de poussée (6) ; et le mécanisme de poussée comprend en outre un ensemble de guidage de production de son (9) ; la tige de poussée (6), le manchon à va-et-vient (7) et l'ensemble de guidage de production de son (9) sont emboîtés de manière coaxiale et coulissante les uns par rapport aux autres ; et l'ensemble de guidage de production de son (9) peut verrouiller le manchon à va-et-vient (7) après un mouvement de va-et-vient du manchon à va-et-vient (7), et l'ensemble de guidage de production de son (9) et la tige de poussée (6) agissent pour générer respectivement un son rapide de démarrage et un son rapide d'arrêt au début et à la fin de la poussée de la tige de poussée (6).
PCT/CN2021/132032 2021-05-26 2021-11-22 Mécanisme de poussée, et dispositif d'injection automatique l'utilisant et méthode d'utilisation associée WO2022247175A1 (fr)

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CN202110577683.7 2021-05-26
CN202110577683.7A CN113368343B (zh) 2021-05-26 2021-05-26 一种推力机构、应用该机构的自动注射装置及其使用方法

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CN113368343B (zh) * 2021-05-26 2022-06-10 宁波易舒医疗科技有限公司 一种推力机构、应用该机构的自动注射装置及其使用方法

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