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WO2022111613A9 - 基底及其制备方法以及基底的用途 - Google Patents

基底及其制备方法以及基底的用途 Download PDF

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WO2022111613A9
WO2022111613A9 PCT/CN2021/133358 CN2021133358W WO2022111613A9 WO 2022111613 A9 WO2022111613 A9 WO 2022111613A9 CN 2021133358 W CN2021133358 W CN 2021133358W WO 2022111613 A9 WO2022111613 A9 WO 2022111613A9
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substrate
alkyl
preparation
formula
independently selected
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PCT/CN2021/133358
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French (fr)
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WO2022111613A1 (zh
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林志峰
孙雷
王�琦
冯叠文
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深圳市真迈生物科技有限公司
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Priority to US18/037,423 priority Critical patent/US20230406983A1/en
Priority to EP21897113.3A priority patent/EP4253434A4/en
Publication of WO2022111613A1 publication Critical patent/WO2022111613A1/zh
Publication of WO2022111613A9 publication Critical patent/WO2022111613A9/zh

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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
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  • Chemical & Material Sciences (AREA)
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Abstract

本发明涉及一种基底及其制备方法及其应用。所称的基底，具有表面，该表面包含与之共价连接的聚合物包被，聚合物包被包含聚合物，聚合物包含如式I所示的重复单元A以及如式II或式III所示的重复单元B：(I), (II), (III) 其中，X选自-O-或-NH-， R 01'、R 01"和R 01"'各自独立地选自-H或C1～C3烷基，R 0选自C1～C10烷基或-(C1-C5烷基)-NH-NHS-PEG4，且R 0包含至少一个R 02取代，至少一个R 02取代各自独立地选自环氧基、氨基或叠氮基，R 03'、R 03"、R 03"'、R 03""、R 04'、R 04"、R 04" '、R 05'、R 05"和R 05"'各自独立地选自-H、C1～C3烷基、酰胺基或酯基，L 1选自C1～C3亚烷基或-C(O)-R 06-C(O)-，R 06选自PEG或烷基二胺。该表面能够更高密度地负载生物分子，满足不断发展的生物分子制备和/或分析需求，且稳定性好。
PCT/CN2021/133358 2020-11-30 2021-11-26 基底及其制备方法以及基底的用途 WO2022111613A1 (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US18/037,423 US20230406983A1 (en) 2020-11-30 2021-11-26 Substrate, and preparation method therefor and use of substrate
EP21897113.3A EP4253434A4 (en) 2020-11-30 2021-11-26 SUBSTRATE AND PRODUCTION METHOD THEREFOR AND USE OF THE SUBSTRATE

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202011375903.XA CN114573764B (zh) 2020-11-30 2020-11-30 聚合物、芯片及其制备方法和应用
CN202011375903.X 2020-11-30

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WO2022111613A1 WO2022111613A1 (zh) 2022-06-02
WO2022111613A9 true WO2022111613A9 (zh) 2022-06-30

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US (1) US20230406983A1 (zh)
EP (1) EP4253434A4 (zh)
CN (1) CN114573764B (zh)
WO (1) WO2022111613A1 (zh)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024093421A1 (zh) * 2022-10-31 2024-05-10 深圳市真迈生物科技有限公司 表面处理方法、测序方法和试剂盒
CN115850577B (zh) * 2023-02-17 2023-10-03 深圳赛陆医疗科技有限公司 一种高生物兼容的聚合物、芯片及其制备方法
CN116925284B (zh) * 2023-07-28 2024-08-02 深圳市大道测序生物科技有限公司 聚合物及其制备方法、基因测序芯片中的应用、测序芯片

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CA2335377C (en) * 2001-03-05 2010-12-14 Bioneer Corporation Bio-molecular microchip and manufacturing process thereof
KR100487167B1 (ko) * 2002-10-30 2005-05-03 (주)바이오니아 바이오칩 및 이의 제조방법
US9173943B2 (en) * 2009-01-12 2015-11-03 The Regents Of The University Of California Imprinted polymer nanoparticles
CN101560061B (zh) * 2009-05-27 2011-08-31 上海交通大学 图型化聚合物刷的制备方法
CN103233274B (zh) * 2013-05-06 2014-12-31 北京化工大学 一种聚合物基三维生物芯片的制备方法
PL3017065T3 (pl) * 2013-07-01 2019-03-29 Illumina, Inc. Funkcjonalizacja powierzchni i szczepienie polimeru bez użycia katalizatora
WO2016066586A1 (en) * 2014-10-31 2016-05-06 Illumina Cambridge Limited Novel polymers and dna copolymer coatings
CN104761745B (zh) * 2015-03-16 2017-11-24 北京化工大学 一种三维生物芯片基片制备方法
CN111171229B (zh) * 2020-02-12 2021-12-28 赛纳生物科技(北京)有限公司 一种核酸固载微球的制备方法
CN111426841A (zh) * 2020-03-31 2020-07-17 中科康磁医疗科技（苏州）有限公司 一种具有防污微凝胶芯片的制备方法、芯片，以及传感器

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US20230406983A1 (en) 2023-12-21
CN114573764B (zh) 2023-08-29
EP4253434A4 (en) 2024-10-30
CN114573764A (zh) 2022-06-03
EP4253434A1 (en) 2023-10-04
WO2022111613A1 (zh) 2022-06-02

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