WO2021241657A1 - Cognitive function examination program and cognitive function examination system - Google Patents

Abstract

The present invention provides a cognitive function examination program and a cognitive function examination device whereby a decline in cognitive function can be perceived at an early stage. The present invention is a cognitive function examination program executed by a computer, the program causing the computer to execute a step for causing a game associated with tasks relating to a cognitive function examination to proceed, a step for receiving an input by an examination subject during play of the game, a step for measuring cognitive function on the basis of the input by the examination subject, and a step for outputting the measured result. The tasks include a recognition task.

Description

Cognitive function test program and cognitive function test system

The present invention relates to a cognitive function test program and a cognitive function test system for testing the cognitive function of a subject.

Conventionally, a cognitive function test device for testing the cognitive function of a subject has been known for diagnosing cognitive disorders such as dementia. For example, Patent Document 1 attempts to provide a cognitive function measuring system capable of evaluating a plurality of cognitive functions on the same scale.

Japanese Unexamined Patent Publication No. 2019-208758

However, in the cognitive function measurement system described in Patent Document 1, although a plurality of cognitive functions are evaluated on the same scale, the reproducibility of the test results is insufficient, and therefore the diagnostic accuracy supports the diagnosis by the doctor. There was a problem that it did not reach the level that can be utilized.

The present invention has been made to solve the above problems, and an object of the present invention is to provide a cognitive function test program and a cognitive function test device that can detect a decline in cognitive function at an early stage.

In order to solve the above problems, the present invention has the following features. (1) It has the task of evaluating orientation, attention, memory, visuospatial cognition, and executive function, which are the main elements of cognitive function, and enables early detection from the stage of mild cognitive impairment (MCI). .. In addition, it has a task to evaluate the executive function in comparison with MoCA-J (Montreal Cognitive Assessment Japanese version), which is conventionally used as one of the tests for screening MCI. (2) Measures are taken to prevent the score from decreasing due to factors other than cognitive function (for example, a simple operation error or delay due to unfamiliarity). (3) Measures have been taken to prevent fluctuations in the score due to different difficulty levels of the problem.
The present invention is a cognitive function test program executed by a computer, wherein the computer advances a game associated with a task related to the cognitive function test, and the inspected person at the time of playing the game. A step of accepting an input, a step of measuring a cognitive function based on the input by the subject, and a step of outputting the measured result are executed, and the task mainly evaluates the cognitive function of orientation. 5 tasks: a task that mainly evaluates the cognitive function of attention, a task that mainly evaluates the cognitive function of visuospatial cognition, a task that mainly evaluates the cognitive function of executive function, and a task that mainly evaluates the cognitive function of memory. Have at least three of the tasks.
In addition, the tasks that mainly evaluate the cognitive function of memory include at least the task of evaluating the cognitive function of immediate recognition and the task of evaluating the cognitive function of delayed recognition, and the task of evaluating the cognitive function of immediate recognition and delayed recognition. It is characterized by the presence of at least one other task with the task of assessing cognitive function.

According to the present invention, it is possible to provide a cognitive function test program and a cognitive function test device that can detect a decline in cognitive function at an early stage.

It is a figure which shows the hardware composition of the cognitive function test system 1. It is a figure which shows the functional structure of the cognitive function test system 1. It is a flowchart which shows the operation of the administrator client terminal 300 in the cognitive function test system 1. It is a flowchart which shows the operation of the user client terminal 100 (measurement account and doctor's account) in the cognitive function test system 1. It is a flowchart which shows the operation of the user client terminal 100 (administrative account) in the cognitive function test system 1. It is a table which shows the kind of each element of the cognitive function evaluated by the cognitive function test system 1 of a particularly preferable embodiment. It is a figure which shows the top screen. It is a figure which shows the operation start screen, and confirms how to use a touch pen here. It is a figure which shows the concrete game start screen associated with the task which mainly evaluates the cognitive function of orientation. It is a figure which shows the problem example of the specific game which mainly evaluates the cognitive function of orientation. It is a figure which shows the concrete game start screen associated with the task which mainly evaluates the cognitive function of memory (immediate recognition). It is a diagram showing an example of a specific game that mainly evaluates the cognitive function of memory (immediate recognition), and shows words to be memorized. It is a diagram showing an example of a specific game that mainly evaluates the cognitive function of memory (immediate recognition), and shows options. It is a figure which shows an example of the specific game which mainly evaluates the cognitive function of memory (immediate recognition), and is the screen which is displayed when it tries to select more than the number of words displayed in FIG. It is a figure which shows the screen which announces the selection again after the game which mainly evaluates the cognitive function of memory (immediate recognition). It is a figure which shows the concrete game start screen associated with the task which mainly evaluates the cognitive function of visuospatial cognition. It is a figure which shows the start screen of the practice problem of the specific game which mainly evaluates the cognitive function of visuospatial cognition. It is a figure which shows the explanation screen of the practice problem of the specific game which mainly evaluates the cognitive function of visuospatial cognition. It is a figure which shows an example of the practice problem of the specific game which mainly evaluates the cognitive function of visuospatial cognition. It is a figure which shows the screen which is displayed when the central figure is selected in the exercise of a specific game which mainly evaluates the cognitive function of visuospatial cognition. It is a figure which shows the screen which can select the repetition of the specific game practice exercise which mainly evaluates the cognitive function of visuospatial cognition. It is a figure which shows the start screen of the production problem of the specific game which mainly evaluates the cognitive function of visuospatial cognition. It is a figure which shows an example of the production problem of a concrete game which mainly evaluates the cognitive function of visuospatial cognition. It is a figure which shows the concrete game start screen associated with the task which mainly evaluates the cognitive function of memory (delay recognition). It is a figure which shows an example of a specific game which mainly evaluates the cognitive function of memory (delayed recognition). It is a figure which shows the start screen of a specific game associated with the task which mainly evaluates the cognitive function of memory (working memory / short-term memory). It is a figure which shows the start screen of the specific game practice problem which mainly evaluates the cognitive function of memory (working memory / short-term memory). It is a figure which shows an example of the practice problem of a specific game which mainly evaluates the cognitive function of memory (working memory / short-term memory). It is a figure which shows an example of the practice problem of a specific game which mainly evaluates the cognitive function of memory (working memory / short-term memory). It is a figure which shows an example of the practice problem of a specific game which mainly evaluates the cognitive function of memory (working memory / short-term memory). It is a figure which shows the screen which can select the repetition of the specific game practice exercise which mainly evaluates the cognitive function of memory (working memory / short-term memory). It is a figure which shows the start screen of the specific game production problem which mainly evaluates the cognitive function of memory (working memory / short-term memory). It is a figure which shows the concrete game start screen associated with the task which mainly evaluates the cognitive function of attention. It is a figure which shows the start screen of the exercise of a specific game which mainly evaluates the cognitive function of attention. It is a figure which shows an example of the practice problem of the specific game which mainly evaluates the cognitive function of attention. It is a figure which shows the screen which can select the repetition of the exercise of a specific game which mainly evaluates the cognitive function of attention. It is a figure which shows the start screen of a specific game production problem which mainly evaluates the cognitive function of attention. It is a figure which shows an example of the production problem of the specific game which mainly evaluates the cognitive function of attention. It is a figure which shows an example of the production problem of the specific game which mainly evaluates the cognitive function of attention. It is a figure which shows the concrete start screen of a game associated with the task which mainly evaluates the cognitive function of a performance function. It is a figure which shows the start screen of a specific game practice problem which mainly evaluates the cognitive function of a performance function. It is a figure which shows the explanation screen of the practice problem of the specific game which mainly evaluates the cognitive function of a performance function. It is a figure which shows an example of the practice problem of the specific game which mainly evaluates the cognitive function of the executive function. It is a figure which shows the screen which can select the repetition of the specific game practice exercise which mainly evaluates the cognitive function of a performance function. It is a figure which shows the start screen of the production problem of a specific game which mainly evaluates the cognitive function of a performance function. It is a figure which shows an example of the production problem of the specific game which mainly evaluates the cognitive function of the executive function. It is a figure which shows an example of the production problem of the specific game which mainly evaluates the cognitive function of the executive function. It is a figure which shows the end screen.

[Embodiment 1]
The cognitive function test system according to the present disclosure is a system for providing a game for testing cognitive function to a plurality of users. Hereinafter, the cognitive function test system will be described with reference to the drawings. It should be noted that the present invention is not limited to these examples, and is indicated by the scope of claims, and it is intended that all modifications within the meaning and scope equivalent to the scope of claims are included in the present invention. NS. In the following description, the same elements will be designated by the same reference numerals in the description of the drawings, and duplicate description will not be repeated.

<Hardware configuration of cognitive function test system 1>
FIG. 1 is a diagram showing a hardware configuration of the cognitive function test system 1. As shown in the figure, the cognitive function test system 1 includes a plurality of user client terminals 100, a cognitive function test diagnosis support server 200, and an administrator client terminal 300. The user client terminal 100 and the administrator client terminal 300 are connected to the cognitive function test diagnosis support server 200 via the network 2. The network 2 is a wired and wireless communication system such as the Internet. The cognitive function test program itself and the data necessary for executing the program according to the present embodiment are stored in the storage devices (not shown) of the user client terminal 100, the cognitive function test diagnosis support server 200, and the administrator client terminal 300. ..

The cognitive function test diagnosis support server 200 may be any computer such as a personal computer, a workstation, a general-purpose computer, or a combination thereof. The cognitive function test diagnosis support server 200 is associated with a Web server 201 that communicates via the network 2, a management server 202 that manages accounts of the cognitive function test system 1, and a task that evaluates each element of the cognitive function. It is configured to have an application server 203 that manages the games, and a database 204 that stores and manages various data. The cognitive function test diagnosis support server 200 may be one computer or a plurality of computers.

The database 204 of the cognitive function test diagnosis support server 200 contains facility information, which is information about the medical facility, and accounts of operators (doctors, subjects, medical facility managers, system managers, etc.) of the cognitive function test system 1. Account information that is information about, game registration information that is registered information such as the execution order of games related to cognitive function test, user log information that is operation history information of the operator of cognitive function test system 1, and cognitive function. Stores game application information, which is program and data necessary for the operation of the game related to the inspection.

The user client terminal 100 may be a mobile terminal such as a smartphone, a feature phone, a PDA (Personal Digital Assistant), or a tablet computer, or may be a desktop computer or the like. It is desirable that the user client terminal 100 can be operated with a touch panel. In FIG. 1, the user client terminal 100 is arranged in a medical facility. The user client terminal 100 may be located at the home of the inspected person, a nursing care facility, a pharmacy, a public hall, or a sports club.

The user client terminal 100 manages accounts of operators (doctors, examinees, medical facility managers, etc.) of the user client terminal 100, displays various reports such as test results by the cognitive function test system 1, and performs a cognitive function test. (Measurement of the cognitive function of the subject by the game application), transmission of the measurement result to the cognitive function test diagnosis support server 200, and the like are executed.

The administrator client terminal 300 may be a mobile terminal such as a smartphone, a feature phone, a PDA (Personal Digital Assistant), or a tablet computer, or may be a desktop computer or the like. The administrator client terminal 300 may have the same configuration as the user client terminal 100, or may have a different configuration. In FIG. 1, the administrator client terminal 300 is arranged in the server operation management facility.

The administrator client terminal 300 manages information on the facility where the user client terminal 100 is located, manages accounts of operators (system administrators, etc.) of the administrator client terminal 300, and operates the cognitive function test system 1. Display various reports of.

<Functional configuration of cognitive function test system 1>
FIG. 2 is a diagram showing a functional configuration of the cognitive function test system 1.

The user client terminal 100 includes a login unit 101 that logs in to the cognitive function test system 1, a user selection unit 102 that selects a user for using the cognitive function test system 1, and a game that executes a game related to the cognitive function test. The execution unit 103, the end confirmation unit 104 that confirms the end of evaluation (execution of various games) of each element of the cognitive function, which is a cognitive function test, and the user information display unit that displays the evaluation result of the cognitive function and outputs a report. 105, a report generation unit 106 that generates a report based on information from the user information display unit 105, a report printing unit 107 that prints a report generated by the report generation unit 106, and issuance of an account of a user in the facility. It has an account information management unit 108 for management, a screen display / voice output unit 109 for screen display and voice output, and a touch panel information input unit 110 for receiving an operator's input by a touch panel.

The cognitive function test system 1 has different accounts depending on the position of the operator, and the authority to the cognitive function test system 1 is different depending on this account. When the user client terminal 100 is used to log in with the "measurement" account (inspector's account) by the login unit 101, the user selection unit 102, the game execution unit 103, and the end confirmation unit 104 can be executed. Become. When logged in by the login unit 101 with a "doctor account" account (doctor account) using the user client terminal 100, the user selection unit 102, the user information display unit 105, the report generation unit 106, and the report printing unit 107 Becomes feasible. When the user client terminal 100 is used to log in with the "administrator" account (facility administrator account) by the login unit 101, the account information management unit 108 can be executed.

The administrator client terminal 300 is from a login unit 301 that logs in to the cognitive function test system 1, a facility / account information management unit 302 that issues and manages an account of a facility administrator, and a facility / account information management unit 302. It has a report generation unit 303 that generates a report based on information, and a report printing unit 304 that prints a report generated by the report generation unit 303.

When logged in by the login unit 301 with an "administrator" account (system administrator account) using the administrator client terminal 300, the facility / account information management unit 302, the report generation unit 303, and the report printing unit 304 Becomes feasible.

The Web server 201 of the cognitive function test diagnosis support server 200 cooperates with each server and performs network protocol processing for the network 2.

The management server 202 of the cognitive function test diagnosis support server 200 includes an account information processing unit 2021 that issues account authority for each account, and a facility / account information management processing unit 2022 that issues account issuance authority to the facility manager's account. And have.

The app server 203 of the cognitive function test diagnosis support server 200 includes a user measurement processing unit 2031 that performs cognitive function measurement processing, display of measurement results, and report generation, and a cognitive level evaluation unit 2032 that evaluates cognitive level. The recognition evaluation value calculation unit 2033 that calculates the recognition evaluation value, the game application information processing unit 2034 that executes each game on the user client terminal 100 side, the reference of the information of the game to be executed, and the game to be re-executed. It has a game registration information processing unit 2035 that registers information, and a game measurement processing unit 2036 that calls game applications in order based on the game registration information and executes them on the user client terminal 100. The game measurement processing unit 2036 mainly has a game selection unit 20361 for selecting a game for a task (smartness task) that evaluates the cognitive function of the knowledge, and a task (memory task) that mainly evaluates the cognitive function of the memory. ) Memory task game selection unit 20362 that selects a game, attention task game selection unit 20363 that mainly selects a task (attention task) game that evaluates the cognitive function of attention, and mainly evaluates the cognitive function of the execution function. Select the game of the task to be performed (executive function task) Select the game of the executive function task game selection unit 20364 and the task (visual space cognitive task) that mainly evaluates the cognitive function of the visual space cognition. It has a portion 20365 and. The game registration information processing unit 2035 adjusts the number of games executed by the inspected person based on the measurement result of the cognitive function by the game executed by the inspected person on the user client terminal 100, or is executed by the inspected person. You can adjust the difficulty of the game you play. For example, the same measurement result can be obtained regardless of whether the subject is already known to have a cognitive impairment or is already known to have no cognitive impairment. In this case, by increasing or decreasing the number of games or adjusting the difficulty level of the game, or by increasing or decreasing the number of games and adjusting the difficulty level of the game, it is possible to easily make a difference between the subjects to be inspected. The accuracy can be improved. In addition, this adjustment makes it possible to detect a subject with mild cognitive impairment, which can be useful for treatment by early detection.

The database 204 of the cognitive function test diagnosis support server 200 includes a facility ID that identifies each facility, facility information that is information about the facility, an administrator account ID that identifies the account of the facility administrator of the facility, and the facility. It has a facility information storage unit 2041 that stores the number of issued accounts in association with each other.

The database 204 of the cognitive function test diagnosis support server 200 obtains an account ID that identifies each account, a facility ID that identifies the facility to which the account belongs, account registration information that is information about the account, and the authority of the account. It has an account information storage unit 2042 that stores the account authority information, which is the information to be shown, in association with each other.

The database 204 of the cognitive function test diagnosis support server 200 stores the user ID assigned to each inspected person in association with the measurement information indicating the measurement result of the inspected person, that is, the user in each game. It has a user measurement information storage unit 2043.

The database 204 of the cognitive function test diagnosis support server 200 identifies the user ID assigned to each inspected person and the game execution order information (specifying each game) indicating the execution order of the games in the problem for the inspected person, that is, the user. It has a game registration information storage unit 2044 that stores data strings arranged in the execution order of game IDs in association with each other.

The database 204 of the cognitive function test diagnosis support server 200 has a game application storage unit 2045 that stores a game ID that identifies each game and the game program itself of the game or data necessary for executing the program in association with each other. ..

<Operation explanation of cognitive function test system 1>
FIG. 3 is a flowchart showing the operation of the administrator client terminal 300 in the cognitive function test system 1. When the operator, that is, the system administrator activates the administrator client terminal 300 and logs in with his / her own account (step S311), the administrator client terminal 300 displays the home screen which is the initial screen (step S312). On the home screen of the administrator client terminal 300, the system administrator selects an account management process (step S313) or a facility management process (step S319).

When the account management process (step S313) is selected, the administrator client terminal 300 accepts the input of the system administrator, and based on the input, newly registers the account (step S314) and generates a report about the account. And printing (steps S315 and S316), editing the account (step S317), and deleting the account (step S318).

When the facility management process (step S319) is selected, the administrator client terminal 300 accepts the input of the system administrator, and based on the input, newly registers the facility (step S320) and generates a report about the facility. And printing (steps S321 and S322), editing the facility (step S323), and deleting the facility (step S324).

FIG. 4 is a flowchart showing the operation of the user client terminal 100 in the cognitive function test system 1, showing the process when logging in with the measurement account, that is, the account for the inspected person, on the left side of the figure. The process when logging in with a doctor's account is shown on the right.

First, the process when logging in with the account for the inspected person will be described. When the inspected person activates the user client terminal 100 and logs in with the account of the facility to which he / she belongs (step S110), the user client terminal 100 displays the user selection screen which is the initial screen (step S111). On the user selection screen of the user client terminal 100, the inspected person selects his / her own account as a user (step S111). Subsequently, the game for the user starts, that is, the measurement of the cognitive function starts (step S112). The number and difficulty levels of the games to be executed here and the execution order of the games may be determined by the game registration information processing unit 2035 of the cognitive function test diagnosis support server 200. In this embodiment, execution of a game mainly for evaluating the cognitive function of sensibleness (step S113), execution of a game for mainly evaluating the cognitive function of memory (immediate recognition) (step S114), and mainly visual space cognition. Execution of the game to evaluate cognitive function (step S115), execution of the game to evaluate the cognitive function of memory (delayed recognition) mainly (step S116), evaluation of cognitive function of memory (working memory / short-term memory) mainly Cognitive function measurement is performed in the order of game execution (step S117), game execution that mainly evaluates the cognitive function of attention (step S118), and game execution that mainly evaluates the cognitive function of the executive function (step S119). Will be done. In any or all of steps S113 to S119, a tutorial screen for explaining the rules and operation method of the game, that is, explaining the play to the inspected person is displayed prior to the start of the game. In any or all of steps S113 to S119, exercises may be executed prior to the start of the game.
Although each game is associated with the task of evaluating each of the above cognitive functions, it may not strictly evaluate one type of cognitive function. For example, in a game for evaluating the cognitive function of the executive function, the cognitive function of visuospatial cognition may be evaluated in addition to the cognitive function of the executive function depending on the game. In this way, one game may be able to evaluate multiple types of cognitive functions. Therefore, even if the game is described as a game that evaluates a specific type of cognitive function, the game is different. It may be possible to evaluate a type of cognitive function. Further, in the case of a game in which a specific type of cognitive function and another type of cognitive function can be evaluated, the game may be described as a game that mainly evaluates a specific type of cognitive function. Therefore, the task may not strictly evaluate one type of cognitive function, and the task may be described as a task that mainly evaluates a specific type of cognitive function.

When the measurement is completed (step S120), this measurement result is transmitted from the user client terminal 100 to the cognitive function test diagnosis support server 200 via the network 2, and the user measurement in the database 204 of the cognitive function test diagnosis support server 200. It is stored in the information storage unit 2043. The measurement result when the measurement is completed in step S120 is the measurement result display in step S123 when the doctor logs in to the user client terminal 100 currently being operated by the inspected person with his / her own account. It may be displayed in the process of.

Next, the process when logging in with a doctor's account will be explained. When the doctor activates the user client terminal 100 and logs in with the account of the facility to which he / she belongs (step S121), the user client terminal 100 displays the user selection screen which is the initial screen (step S122). On the user selection screen of the user client terminal 100, the doctor selects his / her own account as a user (step S122). Subsequently, the measurement result of the cognitive function measurement of the subject belonging to the medical facility of the doctor is displayed (step S123). The measurement result displayed in step S123 may be the measurement result whose measurement is completed in step S119 of the account for the inspected person, or may be stored in the user measurement information storage unit 2043 in the database 204 of the cognitive function test diagnosis support server 200. A certain measurement result may be a measurement result received via the network 2. The doctor inputs the next process with reference to the measurement result displayed in step S123. The user client terminal 100 receives an input from a doctor, and based on the input, an instruction to execute remeasurement (step S124), selection of a game to be executed in the remeasurement (step S125), generation and printing of a report on the measurement result. (Steps S127 and S128) and end (step S129). If the user client terminal 100 currently being operated by a doctor is used to perform remeasurement following steps S124 and S125, the process may proceed from step S126 to step S112. Further, when the remeasurement is performed by another terminal, the process may be returned from step S126 to step S123, and the measurement result for another subject may be displayed, for example.

FIG. 5 is a flowchart showing the operation of the user client terminal 100 in the cognitive function test system 1, and shows the processing when logging in with the management account, that is, the facility manager account. When the operator, that is, the facility manager activates the user client terminal 100 and logs in with his / her own account (step S131), the user client terminal 100 displays the home screen which is the initial screen (step S132). On the home screen of the user client terminal 100, the facility manager selects the account management process (step S133).

When the account management process (step S133) is selected, the user client terminal 100 accepts the input of the facility manager, and based on the input, newly registers the account belonging to the facility (step S134). Generate and print a report for the account belonging to the facility (steps S135 and S136), edit the account belonging to the facility (step S137), and delete the account belonging to the facility (step S138).

<Details of tasks performed by cognitive function test system 1>
The cognitive function test system 1 executes a game associated with a task for evaluating a plurality of types of cognitive functions. FIG. 6 is a table showing the correspondence between the configuration of a task executed in a preferred embodiment of the present invention and the cognitive function mainly evaluated by the task. The system of the present invention has cognitive function (orientation, memory) evaluated by MMSE (Mini-Mental State Examination 1), which is conventionally used as a simple cognitive function test, and MoCA-J, which is used in a test for screening MCI. , Attention, visuospatial cognition), as well as tasks to evaluate the cognitive function of executive function.
Further, the system of the present invention has a task of evaluating at least two types of memory, immediate recognition and delayed recognition, as a task for evaluating the cognitive function of memory, and is between the task of immediate recognition and the task of delayed recognition. , Has at least one different task.
The following describes a particularly preferable combination of tasks and games to be executed in association with the tasks, but the system of the present invention is not limited thereto.
As task 1 for evaluating the cognitive function of orientation mainly in step S113, a game for answering a date and a day of the week is executed. Further, as task 2 for evaluating the cognitive function of mainly memory (immediate recognition) in step S114, a game is executed in which six words are memorized and the next memorized words are answered. Further, as the task 3 of mainly evaluating the cognitive function of visuospatial cognition in step S115, a game of selecting the same figure as the figure shown in the center is executed. Further, as task 4 for evaluating the cognitive function of mainly memory (delayed recognition) in step S116, a game for answering the six words learned in step 114 is executed. Further, as task 5 for evaluating the cognitive function of mainly memory (working memory / short-term memory) in step S117, a game for answering the order in which the displayed circles blink is executed. Further, as the task 6 for evaluating the cognitive function of attention mainly in step S118, a game in which numbers and / or Japanese syllabary are connected in a designated order is executed. Further, as task 7 for mainly evaluating the cognitive function of the executive function in step S119, a game in which a route is created in the order of the indicated numbers and the goal is reached is executed.
In all problems, it is more difficult than MMSE to screen patients with MCI and mild dementia, and there is no ceiling effect (the task is too easy for many subjects to get close to full marks). The difficulty level was set appropriately. In addition, for many questions, the correct or incorrect answer is displayed after the answer, and in the case of an incorrect answer, the correct answer is displayed so that the process can proceed without stress.

FIG. 7 is the top screen of the cognitive function test system 1. When the person to be inspected selects "Next" on this top screen, the operation start screen of FIG. 8 is displayed.

FIG. 8 is an operation start screen of the cognitive function test. When the person to be inspected selects "1", "2", and "Next" on this operation start screen, it is confirmed that there is no problem in operating the touch pen, and the screen transitions to the screen of FIG.

FIG. 9 is a specific game start screen associated with a task that mainly evaluates the cognitive function of orientation. This game is started when the inspected person selects "Start" on this start screen. In this embodiment, the explanation of the game rules and the operation method is displayed prior to the start of the game. FIG. 9 displays a description of the rules of the game and the operation method. The explanation of the rules and the operation method of the game may be given only by characters, may be given by letters and voice, or may be given only by voice.
Orientation is the ability to judge time, place, person, etc. and understand the situation in which one is present. Tasks for assessing orientation include time (season, month, date, day of the week, time), location (prefecture, city, building name, building floor), person (your name, family, friends), etc. There is a game to ask. Of these, it is preferable to ask time.

FIG. 10 is a diagram showing a problem example 1 in this game. FIG. 10 shows the problem of asking what month this month is. Mainly in order to accurately grasp the degree of deterioration of cognitive function of orientation, the difficulty of the problem was set to be gradually increased by asking questions in order from a broad concept to a narrow concept in terms of time. The concept of time includes season, current month, day of the week, current day, and time, and in addition to today, tomorrow, the day after tomorrow, yesterday, and the day of the day before yesterday. The number of questions is preferably 3 to 10, and more preferably 4 to 7.
As a typical example, all 5 questions were asked. The first to fourth questions are about the day of the implementation or the time during the implementation, the first question is the question of "month", the second question is the question of "date", and the third question is "day of the week". The question to ask, the fourth question is the question to ask "time". The fifth question is the question of "date" or "day of the week" of "Asatte" or "Ototoi". The choice for the third question was 7, and the choice for the other questions was 12. It is preferable to arrange these options in chronological order from the left side of the screen. When placed randomly, the contribution of other factors such as attention, perception, and judgment may be greater than orientation. It is expected that the accuracy and reproducibility of the measurement results will be improved by suppressing the learning effect and unifying the difficulty level by setting and devising these problems.
The number of choices can be changed as appropriate, with up to 4 seasons, up to 12 months, preferably 6-12, up to 31 days, preferably 6-20, up to 7 days of the week, preferably 6-30, more preferably. Is 12 to 24.

FIG. 11 is a specific game start screen associated with a task that mainly evaluates the cognitive function of memory (immediate recognition). This game is started when the inspected person selects "Start" on this start screen. In the present embodiment, prior to the start of the game, a description of the rules and operation method of the game is displayed. FIG. 11 displays a description of a game rule and an operation method. The explanation of the rules and the operation method of the game may be given only by characters, may be given by letters and voice, or may be given only by voice.

FIG. 12 is a diagram showing a first screen of problem example 1 in a specific game for mainly evaluating the cognitive function of memory (immediate recognition). As a game for evaluating the cognitive function of memory (immediate recognition), there is a game in which several series, words, pictures, etc. are memorized and answered immediately.
The following describes a preferable game for memorizing words. FIG. 12 displays the words memorized by the inspected person. The number of words to be memorized is preferably 4 to 8, more preferably 5 to 7. The type of word is usually selected from widely used words. Examples of the character type include katakana, hiragana, kanji, and alphabet in Japan, but katakana and hiragana are preferable. In addition, it is preferable that the number of memorized words of katakana and hiragana is as equal as possible. The number of characters is preferably 2 to 5 characters, more preferably 3 to 4 characters. The character type and the number of characters can be changed as appropriate depending on the mother tongue of English. For example, in the case of English, words having 3 to 6 letters of the alphabet are preferable.
As a typical example, the number of memorized words is 6, 6 words are set as 1 group, and 4 groups having different words are prepared and preset in the system (24 words in total). Then, one group is randomly set from four groups. The group preset in the system is preferably 3 to 10.
In word selection, candidate words are selected from Gakken's "Word New Density Basic Word Database by Semantics" based on the following selection criteria in order to maintain homogeneity between groups, and are finally displayed. The words in the group were selected so that they could be easily connected or the first letters of the words did not overlap (I tried to disperse them as much as possible until "A-wa").
[Selection criteria] (1) Nouns, existing ones (abstract words are not selected) (2) Number of characters: 3 and 4 characters (including yoon) (3) Intimacy: 6 or more (Animal and vehicle categories are 5.5) (4) Three words "Katakana" and three words "Hiragana". In addition, as the content of the words, we chose to include various things with different concepts in one group, such as animals, vehicles, food, and tools.
The words to be memorized are selected from, for example, words with an intimacy of 5.5 or more published in Gakken's "Word New Density Basic Word Database by Gakken".
When displaying 6 words, fix to 4 types of display patterns so that 3 words of "Katakana" or 3 words of "Hiragana" are not displayed unevenly in the vicinity, and one of them is randomly selected and displayed. I made it. It is expected that the accuracy and reproducibility of the measurement results will be improved by suppressing the learning effect and unifying the difficulty level by setting and devising these problems.
With the screen of FIG. 12 displayed, the screen of FIG. 13 is displayed after a predetermined time (30 seconds in this embodiment) has elapsed.

FIG. 13 is a diagram showing a second screen of problem example 1 in a specific game for mainly evaluating the cognitive function of memory (immediate recognition). FIG. 13 shows the problem of selecting the words memorized in FIG. One group different from the one group to be memorized (6 words) is randomly selected from the remaining three groups, and 12 words including the memorized group are displayed. In the display of 12 words, there are 8 types so that the correct and incorrect words are not displayed in the vicinity and the 3 words "Katakana" or "Hiragana" are not displayed in the vicinity. It was fixed to the display pattern, and one of them was randomly selected and displayed. It is expected that the reproducibility of measurement results will be improved by setting and devising these problems.
In addition, when the subject selects 6 correct words from 12 words, only 6 words can be selected (7 words or more cannot be selected). It is expected that this device will improve the reproducibility of score calculation. If an attempt is made to select more words than the number of words displayed in FIG. 12, the screen of FIG. 14 is displayed.

FIG. 15 is a diagram showing a third screen of Problem Example 1 in this game. FIG. 15 shows that the words memorized in FIG. 12 are to be selected again later.
After this game, we will mainly play a specific game to evaluate the cognitive function of memory (delay recognition), but once we need to get rid of this game about memory, we will play about 60 seconds as the next game. We set up a specific game that mainly evaluates the cognitive function of visuospatial cognition, which takes about 90 seconds.
Insert at least one game between a specific game that mainly evaluates the cognitive function of memory (immediate recognition) and a specific game that mainly evaluates the cognitive function of memory (delayed recognition), but the time required. It is preferably 30 seconds to 300 seconds, more preferably 60 seconds to 120 seconds.

When "Next" is selected on the screen of FIG. 15, the screen of FIG. 16 is displayed. FIG. 16 is a specific game start screen associated with a task that mainly evaluates the cognitive function of visuospatial cognition. This game is started when the inspected person selects "Start" on this start screen. In this embodiment, the explanation of the game rules and the operation method is displayed prior to the start of the game. The explanation of the rules and the operation method of the game may be given only by characters, may be given by letters and voice, or may be given only by voice. In this game, in order to make the inspected person's understanding of this game uniform, practice questions are given before the actual questions are given. It is expected that the reliability and reproducibility of the measurement results will be improved by reducing the fluctuations in the number of correct answers and the required time due to factors other than the cognitive function such as operation mistakes.

When "Start" is selected on the screen of FIG. 16, the screen of FIG. 17 is displayed. FIG. 17 is a diagram showing a first screen of a specific game practice problem example 1 that mainly evaluates the cognitive function of visuospatial cognition. When "Start" is selected on the screen of FIG. 17, the screen of FIG. 18 is displayed. FIG. 18 is a diagram showing a second screen of practice problem example 1 of this game. In addition to the explanation of the text in FIG. 16, the screen of FIG. 18 was used to explain how to answer directly on the actual question screen, and by experiencing the question answer as a task, the degree of understanding was further improved. When "Start answer" is selected on the screen of FIG. 18, the screen of FIG. 19 is displayed. FIG. 19 is a diagram showing a third screen of practice problem example 1 of this game.
When the central figure is selected in the exercise of FIG. 19, the screen of FIG. 20 is displayed. The screen of FIG. 20 is a screen that guides the user to select from the surroundings when the figure in the middle is pressed by mistake. It is expected that the reproducibility of the measurement results will be improved by reducing the fluctuation of the required time by eliminating the operation error.

When the exercise of FIG. 19 is answered, the screen of FIG. 21 is displayed. FIG. 21 is a diagram showing a fifth screen of practice question example 1 in which a player selects whether to perform a practice question again or proceed to a real question. It is possible to repeat it in case the understanding is insufficient due to overlooking the practice method etc. at one time. However, in order to shorten the examination time, a limit may be set on the number of exercises that can be done, such as a limit of three exercises. When "Practice again" is selected on the screen of FIG. 21, the exercises of this game are displayed. When "Proceed to production" is selected on the screen of FIG. 21, the screen of FIG. 22 is displayed.
FIG. 22 is a diagram showing a first screen of a production problem example 1 of this game. In the actual problem, the difficulty level of the problem was set step by step, and all three problems were set, mainly in order to accurately grasp the degree of deterioration of the visual space recognition function. The first question is fixed to three types as low-difficulty figures (that is, figures that are clearly different from each other), and one type is randomly selected from the three types to be asked. In addition, 6 kinds of figures of choice are shown. The second question is fixed to three types of figures with medium difficulty (that is, figures similar to each other), and one type is randomly selected from the three types to be asked. Six types of figures are shown as choices. The third question is fixed to three types of figures with high difficulty (that is, including figures that are mirror images of each other), and one type is randomly selected from the three types to be asked. Six types are shown as options, but three types of mirror images of each other are included. In each problem, the rotation angle of each figure was fixed at 120 degrees or -120 degrees with respect to the reference central figure. It is expected that the accuracy and reproducibility of the measurement results will be improved by suppressing the learning effect and unifying the difficulty level by setting and devising these problems. When "Start" is selected on the screen of FIG. 22, the screen of FIG. 23 is displayed. FIG. 23 is a diagram showing a second screen of the actual problem example 1 of this game.
In the problem of each difficulty level, the number of figures to be set in advance is not particularly limited, but it is better not to be too large in order to make the difficulty levels uniform, preferably 2 to 5 types, and further preferably 2 to 3 types. It is a seed. The number of figures shown as options in the answer is preferably 4 to 10, and more preferably 5 to 8.
In addition, the figure to be selected has a rotation angle of preferably −150 ° to −30 ° and 30 ° to 150 °, more preferably −60 ° to −130 ° and 60 ° to 130 with respect to the figure shown in the center. °, and the rotation angle is fixed within this range.

When the question of FIG. 23 is answered, the screen of FIG. 24 is displayed. FIG. 24 is a specific game start screen associated with a task that mainly evaluates the cognitive function of memory (delayed recognition). This game is started when the person to be inspected selects to start on this start screen. In this embodiment, the explanation of the game rules and the operation method is displayed prior to the start of the game.
The specific game configuration that mainly evaluates the cognitive function of memory (delayed recognition) is the same as the specific game configuration that mainly evaluates the cognitive function of memory (immediate recognition), and is mainly the above-mentioned memory. It answers the same words memorized in a specific game that evaluates the cognitive function of (immediate recognition).

When "Start" is selected on the screen of FIG. 24, the screen of FIG. 25 is displayed. FIG. 25 is a diagram showing a first screen of problem example 1 of this game. FIG. 25 shows the problem of selecting the words memorized in FIG. One group different from the one group (6 words) to be memorized is randomly selected from the remaining 3 groups, and a total of 12 words are displayed. In the display of 12 words, there are 8 types so that the correct and incorrect words are not displayed in the vicinity and the 3 words "Katakana" or "Hiragana" are not displayed in the vicinity. It was fixed to the display pattern and displayed randomly from them. It is expected that the accuracy and reproducibility of the measurement results will be improved by suppressing the learning effect and unifying the difficulty level by setting and devising these problems.
When the subject selects 6 words from 12 words, only 6 words can be selected (7 words or more cannot be selected). It is expected that this device will improve the reproducibility of score calculation.

When the question in FIG. 25 is answered, the screen in FIG. 26 is displayed. FIG. 26 is a specific game start screen associated with a task that mainly evaluates the cognitive function of memory (working memory / short-term memory). This game is started when the inspected person selects "Start" on this start screen. In the present embodiment, prior to the start of the game, a description of the rules and operation method of the game is displayed. The explanation of the rules and operation method of the game may be given only by letters, may be given by letters and voice, or may be given only by voice. In this game, exercises are given before the actual questions are given in order to have the same level of understanding of the subject's tasks. It is expected that the reliability and reproducibility of the measurement results will be improved by reducing the fluctuations in the number of correct answers and the required time due to factors other than the cognitive function such as operation mistakes.

When "Start" is selected on the screen of FIG. 26, the screen of FIG. 27 is displayed. FIG. 27 is a diagram showing a first screen of a specific game practice problem example 1 that mainly evaluates the cognitive function of memory (working memory / short-term memory). When "Start" is selected on the screen of FIG. 27, the screen of FIG. 28 is displayed. FIG. 28 is a diagram showing a second screen of practice problem example 1 of this game. FIG. 29 is displayed without any operation. FIG. 29 is a diagram showing a third screen of practice problem example 1 of this game. In addition to the explanation of the text in FIG. 26, the screen of FIG. 29 was used to explain how to answer directly on the actual question screen, and by experiencing the question answer as a task, the degree of understanding was further improved. When "Start answer" is selected on the screen of FIG. 29, the screen of FIG. 30 is displayed. By setting this "start answer" button, the timing of the start of the answer was clarified and a device was devised to prevent erroneous operation. FIG. 30 is a diagram showing a fourth screen of practice problem example 1 of this game.

When the exercise of FIG. 30 is answered, the screen of FIG. 31 is displayed. FIG. 31 is a diagram showing a fifth screen of Exercise 1 Example 1, in which the user selects whether to perform the exercise again or proceed to the actual exercise. It is possible to repeat it in case the understanding is insufficient due to overlooking the practice method etc. at one time. However, in order to shorten the examination time, a limit may be set on the number of exercises that can be done, such as a limit of three exercises. When "Practice again" is selected on the screen of FIG. 31, the exercises of this game are displayed. When "Proceed to production" is selected on the screen of FIG. 31, the screen of FIG. 32 is displayed.
FIG. 32 is a diagram showing a first screen of a production problem example 1 of this game. In the actual problem, the difficulty level of the problem was set step by step in order to accurately grasp the degree of deterioration of the cognitive function of the memory (working memory / short-term memory), and all three problems were set. The number of questions is preferably 2 to 5 questions, and more preferably 3 to 4 questions. In each problem, the number of blinks is preferably 2 to 10, and more preferably 3 to 8. Also, it is preferable to increase the number of blinks as the problem progresses.
Typically, the first question is fixed to 3 as the number of blinks with a low difficulty level, and one type of blinking pattern is randomly selected from four types having the same difficulty level. In order to make the same difficulty, when there are four lights as shown in FIG. 30, the rotation target (0 °, 90 °, 180 °, 270 °) and the rotation target (0 °, 90 °, 180 °, 270 °) and the rotation target (0 °, 90 °, 180 °, 270 °) and the rotation target for one blinking pattern, and There are eight patterns of each mirror image. It is appropriately selected from these eight patterns and set in the system in advance.
The second question is fixed at 4 as the number of blinks with a medium difficulty level, and one type of blinking pattern is randomly selected from the four types having the same difficulty level. The third question is fixed at 5 as the number of blinks with a high degree of difficulty, and one type of blinking pattern is randomly selected from four types having the same difficulty level. Even if you make a mistake in the answer to each question, the answer is set so that you can answer until the end without ending the answer at the time of the mistake, and the number of answers by the implementers is the same. It is expected that the reproducibility of measurement results and score calculation will be improved by setting and devising these problems.
Further, as another typical example, the first question is fixed to 3 as the number of blinks with a low difficulty level, and one type of blinking pattern is randomly selected from four types having the same difficulty level. In order to make the same difficulty, when there are four lights as shown in FIG. 29, the rotation target (0 °, 90 °, 180 °, 270 °) and the rotation target (0 °, 90 °, 180 °, 270 °) and the rotation target (0 °, 90 °, 180 °, 270 °) and the rotation target for one blinking pattern, and There are eight patterns of each mirror image. It is appropriately selected from these eight patterns and set in the system in advance. If the answer is correct in the first question, the second question is set to 4 as the number of blinks with a medium difficulty level, and one type of blinking pattern is randomly selected from four types having the same difficulty level. If the first question is incorrect, 3 will be asked again as the number of blinks with the same difficulty and lower difficulty. Similarly, if the answer is correct, the number of blinks will increase by one from the previous question in the next question, and if the answer is incorrect, the number of blinks will be the same as in the previous question in the next question. As a result, the pattern of the number of blinks of all three questions is selected from the combination of 3-3-3, 3-3-4, 3-4-4, and 3-4-5. The number of blinks that increases with the correct answer is not particularly limited, but it is better not to be too large in order to sensitively grasp the deterioration of the cognitive function of memory (working memory / short-term memory), preferably 1 to 4, and further. It is preferably 1 to 2. Even if you make a mistake in the answer to each question, the answer is set so that you can answer until the end without ending the answer at the time of the mistake, and the number of answers by the implementers is the same. It is expected that the accuracy and reproducibility of measurement results will be improved by setting and devising these problems. If you select "Start" on the screen of FIG. 32, problems with this game will be displayed. The illustration of the actual question of this game is omitted because it is the same as the practice question.

When you answer the question of this game, the screen of FIG. 33 is displayed. FIG. 33 is a specific game start screen associated with a task that mainly evaluates the cognitive function of attention. This game is started when the inspected person selects "Start" on this start screen. In the present embodiment, prior to the start of the game, a description of the rules and operation method of the game is displayed. The explanation of the rules and the operation method of the game may be given only by characters, may be given by letters and voice, or may be given only by voice. In this game, exercises are given before the actual questions are given in order to have the same level of understanding of the subject's tasks. It is expected that the reliability and reproducibility of the measurement results will be improved by reducing the fluctuations in the number of correct answers and the required time due to factors other than the cognitive function such as operation mistakes.

When "Start" is selected on the screen of FIG. 33, the screen of FIG. 34 is displayed. FIG. 34 is a diagram showing a first screen of a specific game practice problem example 1 that mainly evaluates the cognitive function of attention. When "Start" is selected on the screen of FIG. 34, the screen of FIG. 35 is displayed. FIG. 35 is a diagram showing a second screen of practice problem example 1 of this game. By adding a dotted line between the circled numbers 1 and the circled numbers 2, we have devised a way to guide the first operation and promote understanding. In addition, if the progress is not in the correct order, an "x" is displayed to clearly indicate that it is a mistake, and by proceeding only in the correct order, a device to prevent erroneous operation was devised. By experiencing the question and answer as a work, I devised a way to align the understanding.

When the exercise of FIG. 35 is answered, the screen of FIG. 36 is displayed. FIG. 36 is a diagram showing a third screen of Exercise 1 Example 1, in which the user selects whether to perform the exercise again or proceed to the actual exercise. It is possible to repeat it in case the understanding is insufficient due to overlooking the practice method etc. at one time. However, in order to shorten the examination time, a limit may be set on the number of exercises that can be done, such as a limit of three exercises. When "Practice again" is selected on the screen of FIG. 36, the exercises of this game are displayed. When "Proceed to production" is selected on the screen of FIG. 36, the screen of FIG. 37 is displayed.
FIG. 37 is a diagram showing a first screen of a production problem example 1 of this game. In this game, letters and numbers are written in 〇 (hereinafter referred to as "balls"), and these balls are connected in order. Symbols used for balls in this game include those that everyone understands the ascending order, such as the Japanese syllabary (hiragana or katakana) alphabet and numbers (Arabic numerals, Roman numerals, etc.). In the actual problem, the difficulty level of the problem was set step by step, mainly in order to accurately grasp the degree of deterioration of the cognitive function of attention, and all three problems were set. The first question is a low-difficulty problem, where the number of balls connected by a line is 10 and the questions are fixed in the order of "numbers" such as "1 → 2 → 3 → 4 → 5 →". As for the arrangement pattern of, one type is randomly selected from four types having the same difficulty level and the question is given. As a pattern of the same difficulty, eight patterns of a rotation target (0 °, 90 °, 180 °, 270 °) and a mirror image thereof are typical, but the angle of the rotation target is limited. If not, there are more patterns. Some of these patterns are appropriately selected and preset in the system. The second question is a medium difficulty problem, and the number of balls connected by a line is fixed to 14 and the question content is fixed in the order of "Hiragana" with "A → I → U → E → O →". , One type of ball placement pattern is randomly selected from four types with the same difficulty level. In the third question, the difficulty is a problem, the number of balls connected by a line is 14, and the question content is fixed alternately as "number" and "hiragana" with "1 → a → 2 → i → 3 →". However, one of the four ball placement patterns with the same difficulty level is randomly selected and set. It is expected that the accuracy and reproducibility of the measurement results will be improved by suppressing the learning effect and unifying the difficulty level by setting and devising these problems.
The number of balls connected by a line is preferably 5 to 30, and more preferably 7 to 20.
When "Start" is selected on the screen of FIG. 37, the problem of this game is displayed. FIG. 38 is a diagram showing a first screen of a production problem example 1 of this game. FIG. 39 is a diagram showing a first screen of a production problem example 2 (problem example different from FIG. 38) of this game.

When you answer the question of this game, the screen of Fig. 40 is displayed. FIG. 40 is a specific game start screen associated with a task that mainly evaluates the cognitive function of the executive function. This game is started when the inspected person selects "Start" on this start screen. In the present embodiment, prior to the start of the game, a description of the rules and operation method of the game is displayed. The explanation of the rules and the operation method of the game may be given only by characters, may be given by letters and voice, or may be given only by voice. In this game, exercises are given before the actual questions are given in order to have the same level of understanding of the subject's tasks.

When "Start" is selected on the screen of FIG. 40, the screen of FIG. 41 is displayed. FIG. 41 is a diagram showing a first screen of practice problem example 1 of this game. When "Start" is selected on the screen of FIG. 41, the screen of FIG. 42 is displayed. FIG. 42 is a diagram showing a second screen of practice problem example 1 of this game. On the screen of FIG. 42, an easy-to-understand operation explanation is given by explaining using a moving image. When "Start" is selected on the screen of FIG. 42, the screen of FIG. 43 is displayed. FIG. 43 is a diagram showing a third screen of practice problem example 1 of this game, and by adding a gray guide line, it is easy to imagine the operation. By experiencing the question and answer as a work, I devised a way to align the understanding. It is expected that the reliability and reproducibility of the measurement results will be improved by reducing the fluctuations in the number of correct answers and the required time due to factors other than the cognitive function such as operation mistakes.

When the exercise of FIG. 43 is answered, the screen of FIG. 44 is displayed. FIG. 44 is a diagram showing a fourth screen of Exercise 1 Example 1, in which the user selects whether to perform the exercise again or proceed to the actual exercise. It is possible to repeat it in case the understanding is insufficient due to overlooking the practice method etc. at one time. However, in order to shorten the examination time, a limit may be set on the number of exercises that can be done, such as a limit of three exercises. When "Practice again" is selected on the screen of FIG. 44, the exercises of this game are displayed. When "Proceed to production" is selected on the screen of FIG. 44, the screen of FIG. 45 is displayed.
FIG. 45 is a diagram showing a first screen of a production problem example 1 of this game. In the actual problem, the difficulty level of the problem was set step by step, mainly in order to more accurately grasp the degree of deterioration of the executive function, and all three problems were set. The first question is a low-difficulty problem, with one place ("x" part) that cannot be passed by the number of squares (4 x 4), and the question pattern (arrangement of numbers and "x") is the same difficulty level. One type is randomly selected from two types and the question is given. In order to make the same difficulty, there are eight patterns of rotation targets (0 °, 90 °, 180 °, 270 °) and mirror images of each for one route pattern. From these, 2 to 8 are appropriately selected and set in the system in advance. If the start position and goal position are fixed, another pattern of the same difficulty level for one route (a line-symmetrical route with respect to the straight line connecting the start and goal: this is a target for 270 ° rotation). (Same as the root of the mirror image) exists, so it is preferable to set these two in the system in advance. The second question is a medium difficulty problem, with three places ("x" places) that cannot be passed by the number of squares (4 x 4), and the question pattern (arrangement of numbers and "x") is the same difficulty level. One type is randomly selected from the two types and the question is given. The third question is a high-difficulty problem, with four points (“x” points) that cannot be passed by the number of squares (6 × 6), and the question patterns (arrangement of numbers and “x”) are at the same difficulty level. One type is randomly selected from two types and the question is given. Further, in the second and third questions, when creating a route in the order of numbers, there is at least one place where the goal can be reached only by a detour route instead of the shortest route. It is expected that the accuracy and reproducibility of the measurement results will be improved by suppressing the learning effect and unifying the difficulty level by setting and devising these problems.
When "Start" is selected on the screen of FIG. 45, the problem of this game is displayed. FIG. 46 is a diagram showing a first screen of problem example 1 of this game. FIG. 47 is a diagram showing a first screen of problem example 2 (problem example different from FIG. 46) of this game.

When the question of this game is answered, the screen of FIG. 48 is displayed. FIG. 48 is an end screen. By selecting "End" on this end screen, the measurement in step S120 of FIG. 4 is completed.
In a preferred embodiment, for each of the above game questions, whether the subject's answer is correct or incorrect is displayed, and if the subject's answer is incorrect, the correct answer is displayed.
Depending on the type of game, even if the system does not explicitly indicate whether the answer is correct or incorrect, whether the subject's answer is practically correct or incorrect, such as reaching the goal (correct) or time out (error). It suffices if the subject can recognize.

In this embodiment,
1. 1. Tasks related to recent memory (immediate recognition and delayed recognition) that decline from the beginning in Alzheimer's disease were incorporated (task 2, task 4).
2. 2. Exercises were set (4 tasks: task 3, task 5, task 6, task 7). That is, by setting exercises, it is possible to make the test subject's understanding of the task uniform, and it is possible to prevent the score from fluctuating due to factors other than the deterioration of cognitive function.
3. 3. We devised tasks to prevent erroneous operations (2 tasks: task 5, task 6). That is, by modifying the question to prevent erroneous operation and changing the answering method, it is possible to suppress the fluctuation of the score due to factors other than the deterioration of cognitive function.
4. We devised a problem to improve reproducibility (all tasks). That is, the accuracy can be improved by fixing the number of questions and adjusting the difficulty level.
5. For all problems, the aim was to screen patients with mild cognitive impairment and mild dementia, and the difficulty was set appropriately so that the ceiling effect did not occur.
6. For all questions, an index (each score) that objectively evaluates the cognitive function of the corresponding task from the correct answer rate and answer time is created, and an index that objectively evaluates the cognitive function of the inspection system that integrates these indexes. (Total score) was created. Furthermore, by statistical processing, each more optimal score and total score can be calculated.

Based on the above, according to the present embodiment, the following effects can be obtained by a system that has a small stress load on the subject and can be inspected in a short time, and can be utilized for supporting the diagnosis of a doctor.
1. 1. Cognitive decline can be measured.
2. 2. You can screen for suspicion of dementia.

[Realization by software]
Each block having a functional configuration shown in FIG. 2 may be realized by a logic circuit (hardware) formed in an integrated circuit (IC chip) or the like, or by software using a CPU (Central Processing Unit). You may.

In the latter case, the user client terminal 100, the cognitive function test diagnosis support server 200, and the administrator client terminal 300 are a CPU that executes an instruction of a program that is software that realizes each function, and the above program and various data are computers (or). It is equipped with a ROM (ReadOnlyMemory) or a storage device (these are referred to as "recording media") readable by a CPU), a RAM (RandomAccessMemory) for expanding the above program, and the like. Then, the object of the present invention is achieved by the computer (or CPU) reading the program from the recording medium and executing the program. As the recording medium, a "non-temporary tangible medium", for example, a tape, a disk, a card, a semiconductor memory, a programmable logic circuit, or the like can be used. Further, the program may be supplied to the computer via any transmission medium (communication network, broadcast wave, etc.) capable of transmitting the program. It should be noted that one aspect of the present invention can also be realized in the form of a data signal embedded in a carrier wave, in which the above program is embodied by electronic transmission.

The present invention is not limited to the above-described embodiment, and various modifications can be made within the scope of the claims, and the embodiment obtained by appropriately combining the technical means disclosed in the different embodiments. Is also included in the technical scope of the present invention.

The embodiments disclosed this time should be considered to be exemplary in all respects and not restrictive. The scope of the present invention is shown by the scope of claims rather than the above description, and is intended to include all modifications within the meaning and scope equivalent to the scope of claims.

This application claims priority based on Japanese Patent Application No. 2020-94682 filed on May 29, 2020, and incorporates all the contents described in the Japanese patent application.

1 ... Cognitive function test system, 2 ... Network, 100 ... User client terminal, 200 ... Cognitive function test diagnosis support server, 300 ... Administrator client terminal.

Claims (18)

1. A cognitive function test program run by a computer
   To the computer
   Steps to progress the game associated with tasks related to cognitive function testing,
   The step of accepting the input by the inspected person at the time of playing the game, and
   The step of evaluating cognitive function based on the input by the subject and
   The step to output the evaluation result and
   To execute,
   The tasks include a task to evaluate cognitive function of orientation, a task to evaluate cognitive function of attention, a task to evaluate cognitive function of visuospatial cognition, a task to evaluate cognitive function of executive function, and a task of memory. Have at least 3 of the 5 tasks for assessing cognitive function,
   A cognitive function test program characterized by this.
2. The task of evaluating the cognitive function of memory includes at least a task of evaluating cognitive function of immediate recognition and a task of evaluating cognitive function of delayed recognition.
   There is at least one other task between the task of assessing cognitive function of immediate recognition and the task of assessing cognitive function of delayed recognition.
   The cognitive function test program according to claim 1.
3. Further steps to perform the exercises when playing the game,
   The cognitive function test program according to claim 1 or 2.
4. The task includes at least one task including a step to prevent erroneous operation.
   The cognitive function test program according to any one of claims 1 to 3.
5. The task comprises at least one task that includes a step to improve reproducibility.
   The cognitive function test program according to any one of claims 1 to 4.
6. The task to improve the reproducibility is
   There are 2 to 8 fixed question groups set, including a game in which one is randomly selected from the questions.
   The cognitive function test program according to claim 5.
7. The above 2 to 8 fixed problem groups are 8 of 0 ° rotation target (itself), 90 ° rotation target, 180 ° rotation target, 270 ° rotation target, and their mirror images for one problem pattern. Selected from the street,
   The cognitive function test program according to claim 6.
8. The reproducible task includes a game of memorizing words.
   The words to remember are selected from words with an intimacy of 5.5 or higher.
   The cognitive function test program according to claim 5.
9. The output step creates an evaluation index based on correct / incorrect information (correct answer rate) indicating the correctness of the input by the inspected person and time information (answer time) indicating the time required for the input by the inspected person.
   The cognitive function test program according to any one of claims 1 to 8.
10. It is a cognitive function test system
    The cognitive function test system is
    A memory unit that stores the cognitive function test program,
    A control unit that controls the operation of the cognitive function test system by executing the cognitive function test program is provided.
    The control unit
    Progress the game associated with the task related to cognitive testing,
    Accepting the input by the inspected person when playing the game,
    Cognitive function was evaluated based on the input by the subject and
    The result of the above evaluation is output.
    The tasks include a task to evaluate cognitive function of orientation, a task to evaluate cognitive function of attention, a task to evaluate cognitive function of visuospatial cognition, a task to evaluate cognitive function of executive function, and a task of memory. Have at least 3 of the 5 tasks for assessing cognitive function,
    A cognitive function test system characterized by this.
11. The task of evaluating the cognitive function of memory includes at least a task of evaluating cognitive function of immediate recognition and a task of evaluating cognitive function of delayed recognition.
    The cognitive function test system according to claim 10, wherein there is at least one other task between the task of evaluating the cognitive function of immediate recognition and the task of evaluating the cognitive function of delayed recognition.
12. Perform gameplay exercises,
    The cognitive function test system according to claim 10 or 11.
13. The task includes at least one task including a step to prevent erroneous operation.
    The cognitive function test system according to any one of claims 10 to 12, wherein the cognitive function test system is characterized.
14. The task comprises at least one task that includes a step to improve reproducibility.
    The cognitive function test system according to any one of claims 10 to 13.
15. The task to improve the reproducibility is
    There are 2 to 8 fixed question groups set, including a game in which one is randomly selected from the questions.
    The cognitive function test system according to claim 14.
16. The above 2 to 8 fixed problem groups are 0 ° rotation target (itself), 90 ° rotation target, 180 ° rotation target, 270 ° rotation target, and their mirror image corps for one problem pattern. The cognitive function test system according to claim 15, wherein the system is selected from eight ways.
17. The reproducible task includes a game of memorizing words.
    The words to remember are selected from words with an intimacy of 5.5 or higher.
    The cognitive function test system according to claim 14.
18. The output step creates an evaluation index based on correct / incorrect information (correct answer rate) indicating the correctness of the input by the inspected person and time information (answer time) indicating the time required for the input by the inspected person.
    The cognitive function test system according to any one of claims 10 to 17, wherein the cognitive function test system is characterized.

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