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WO2020007186A1 - 一种带齿管悬提线 - Google Patents

一种带齿管悬提线 Download PDF

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Publication number
WO2020007186A1
WO2020007186A1 PCT/CN2019/091441 CN2019091441W WO2020007186A1 WO 2020007186 A1 WO2020007186 A1 WO 2020007186A1 CN 2019091441 W CN2019091441 W CN 2019091441W WO 2020007186 A1 WO2020007186 A1 WO 2020007186A1
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WO
WIPO (PCT)
Prior art keywords
toothed
lactide
tooth
tube
teeth
Prior art date
Application number
PCT/CN2019/091441
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English (en)
French (fr)
Inventor
包一红
徐秀忠
张志萍
Original Assignee
浙江中在医疗科技有限公司
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Publication of WO2020007186A1 publication Critical patent/WO2020007186A1/zh

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166Sutures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/06Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0446Means for attaching and blocking the suture in the suture anchor
    • A61B2017/0461Means for attaching and blocking the suture in the suture anchor with features cooperating with special features on the suture, e.g. protrusions on the suture
    • A61B2017/0462One way system, i.e. also tensioning the suture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0464Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors for soft tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B2017/06057Double-armed sutures, i.e. sutures having a needle attached to each end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166Sutures
    • A61B2017/06176Sutures with protrusions, e.g. barbs

Definitions

  • the invention relates to medical instruments, in particular to a suspension wire for plastic surgery.
  • Suspension of skin tissue with absorbable or non-absorbable threads to achieve facial rejuvenation has been used for many years.
  • the working principle is that the suspensory thread has a structural member that can generate resistance in the reverse direction. After it is introduced into the facial tissue by a suture needle, it is lifted in the opposite direction, and the generated reverse resistance will promote the tissue to improve. To achieve the goal of treating mild and moderate senile dysfunction.
  • This type of suspension line is mainly divided into three types in terms of its structure and method characteristics.
  • One type is a suspension line composed of teeth that can generate resistance in the reverse direction.
  • the second type is the whole.
  • Thermoplastic suspension lines, including the full length of the body and the structural components that can generate resistance in the reverse direction are all suspension lines formed by hot pressing or injection molding; the third type is the structural components that can generate resistance in the reverse direction.
  • a suspension line consisting of a hollow cone on a wire.
  • This type of suspension thread that is cut to form teeth is a single-stranded spinning thread that is strengthened by stretching and orientation.
  • the teeth are generated by cutting the thread itself in a certain direction to form many inverted teeth.
  • CN101027168A discloses Barbed suture. The lifting principle is: when the suspending line enters the tissue, the direction of the teeth conforms to the direction of travel. When the pulling direction is reversed, the tip of the teeth inserts into the tissue and generates a pulling force to lift the tissue.
  • thermoplastic suspension line is formed with many inverted teeth on the wire body by hot pressing or injection molding.
  • the teeth grow from the wire body and are integrated with the wire body without cutting, such as Johnson's fish bone line.
  • the lifting principle is the same as this type of suspension line that is cut to form teeth.
  • the hollow cone suspension thread is a hollow cone that is injection-molded and hung on a thread body.
  • the thread body can be a single-stranded spinning thread reinforced by stretching and orientation, or a multi-strand braided thread, and along this line
  • the body is knotted at regular intervals, and the hollow cone is fixed between every two knots, as disclosed in US7582105B2 and CN201404310Y.
  • the principle of lifting is that when the suspending line enters the tissue, the direction of the smaller tip of the cone conforms to the direction of travel, and when pulling in the opposite direction, the tail of the larger cone generates reverse resistance, which drives the tissue to lift.
  • Tooth suspension lines that are cut to form teeth Because the tooth body is not hard enough, it is easy to deform, flip or break when pulled in the opposite direction, so the pulling strength of the tooth is also the smallest. At the same time, because the wire body is damaged by cutting, its tensile strength is also small , Easy to be pulled off, only suitable for pulling small parts with small pull requirements.
  • the overall thermoplastic suspension line has thicker teeth and higher pulling strength, but the tensile strength of the thread body is much smaller than that of a single-stranded spinning yarn of the same diameter.
  • the same strength and processability of the strand spinning thread often requires increasing the diameter of the thread body, which may cause inflammatory reactions caused by too many implants or patient discomfort.
  • Hollow cone suspension line its thread body is also a single-spun or multi-strand braided yarn reinforced by stretching orientation. The strength is greater, but the hollow cone has no tooth structure, but only depends on the reverse resistance of the cone. Pulling force is generated. If the pulling force is excessive, slipping may occur.
  • an object of the present invention is to provide a toothed tube suspension line, which has a higher strength and does not break or slip off when pulled.
  • a toothed pipe suspension line includes a wire body and a toothed pipe arranged in series on the wire body;
  • a wire knot for limiting the position of the toothed pipe is provided on the wire body
  • the toothed tube includes a hollow tube body and teeth provided on the outer wall of the hollow tube and protruding outward.
  • the toothed tube suspension line is mainly composed of a thread body and a toothed tube.
  • the thread body is a single-stranded spinning thread or a multi-strand braided wire reinforced by stretching and orientation, and has good thread body strength.
  • the pipe is made of thermoplastic. Through the tooth-shaped protrusions on the pipe body, good tooth strength is achieved, and no breakage or slippage occurs during pulling.
  • the diameters of the two ends of the hollow tube body are the same or close to each other, and the size of the knot is larger than the inner diameter of the hollow tube body.
  • a cross section of a tooth root to a tooth tip of the tooth gradually decreases, and the tooth tip is inclined to one side along an axis of the hollow pipe body.
  • each toothed tube is provided with three or more teeth, and the tip angles of all the teeth are the same.
  • the teeth are at any position on the hollow tube wall.
  • any two teeth are not on the same circumferential line of the hollow tube wall.
  • the two teeth of the toothed tube make an arbitrary angle along the circumferential direction.
  • the distance between two adjacent teeth (5) on the same hollow pipe body along the axial direction of the hollow pipe body is 0-5 mm.
  • the length from the root of the tooth to the tip of the tooth is not more than 5 mm, and the width of the root of the tooth along the axial direction of the hollow pipe body is 0.1-4 mm, and the tooth of the tooth The thickness of the root along the circumferential direction of the hollow pipe body is greater than 0.2 mm.
  • the inclination of the tooth tips of the teeth is 10-80 °, and the angle generally refers to an included angle between the tooth body and the axial direction of the hollow pipe.
  • the knots distributed on the wire body may be knots knotted by the wire body itself or welded knots, and the distance between the two knots may be arbitrarily adjusted.
  • the thread body is made of an absorbent material through stretch orientation or multi-strand braiding; the toothed pipe is made of an absorbable material by injection molding.
  • Absorbable materials include: L-lactide, DL-lactide, glycolide, caprolactone, trimethylene carbonate, homopolymers or copolymers, homopolymers or copolymers of dioxocyclohexanone Of blends.
  • the toothed pipe suspension line of the present invention wherein the material of the toothed pipe is an L-lactide / glycolide copolymer, and preferably, the molar percentage content of the L-lactide is 75% -95 %, The molar percentage content of glycolide is 5% -25%.
  • the toothed pipe suspension line of the present invention wherein the material of the toothed pipe is an L-lactide / DL-lactide-containing copolymer, and preferably, the molar percentage content of L-lactide is 60 % -95%, and the molar percentage of DL-lactide is 5% -40%.
  • the toothed pipe suspension line of the present invention has the following advantages:
  • the thread body of the suspension line with a toothed tube of the present invention is a single-stranded spinning line or a multi-strand braid reinforced by stretching orientation. Thread, its thread body has greater tensile strength.
  • the structure of the suspension pipe with toothed tube of the present invention can generate resistance in the reverse direction is an injection-molded toothed tube.
  • the tooth pull strength and the wire body tensile strength Both are larger, and at the same time, they have a stronger hooking force on soft tissues than the injection-molded hollow cone.
  • the present invention combines the advantages of the overall thermoplastic suspension line with its strong pulling strength of the teeth and the strength of the hollow body of the hollow cone suspension line. Compared with the hollow cone suspension line, the tension strength of the two bodies is equivalent.
  • the toothed tube suspension line of the present invention has a greater hooking and pulling force of the teeth on the tissue.
  • FIG. 1 is a schematic diagram of a toothed pipe suspension line according to the present invention.
  • FIG. 2 is a schematic view of a toothed tube on a toothed tube suspension line of the present invention.
  • FIG. 1 is a toothed pipe suspension line of the present invention.
  • the toothed pipe suspension line includes a woven or single-smooth smooth thread body 1, and a plurality of knots 2 are distributed on the thread body.
  • a toothed tube 3 is connected in series between the wire knots on the thread body, the toothed tube is a hollow tube body 4, and the outer wall of the hollow tube is provided with teeth 5 protruding outside the tube body.
  • the number of toothed pipes 3 is generally three or more (only two are shown in FIG. 1), and the diameters of the two ends of the hollow pipe body are the same or close to each other.
  • the teeth 5 protruding from the outside of the tube are composed of two or more teeth whose tooth tips are inclined in one direction, and can be randomly distributed on the tube.
  • FIG. 2 is a schematic structural diagram of a toothed pipe 3.
  • the relative positions of the two teeth on the pipe body are not on the same circumferential line;
  • the teeth are arranged at any angle along the circumferential direction.
  • the two teeth are arranged at an angle of 120 ° along the circumferential direction.
  • each of the teeth has an angle of 120 ° along the circumferential direction.
  • the toothed pipe suspension line of the present invention wherein the distance between each tooth of the teeth 5 protruding outside the pipe body along the longitudinal direction of the pipe body is 0-5 mm.
  • the inclination of the tooth tips of the teeth 5 protruding outside the pipe is 10-80 °.
  • the knots 2 distributed on the wire body can be knots welded by the wire body or welded knots, and the distance between the two knots can be arbitrarily adjusted;
  • the size is larger than the inner diameter of the tube.
  • the toothed pipe suspension line of the present invention wherein the thread body and the toothed pipe are made of an absorbable material, and the absorbable material includes: L-lactide, DL-lactide, glycolide, caprolactone Homopolymers or copolymers of esters, trimethylene carbonate, p-dioxane, blends of homopolymers or copolymers.
  • the toothed pipe suspension line of the present invention wherein the material of the toothed pipe is an L-lactide / glycolide copolymer, and preferably, the molar percentage content of the L-lactide is 75% -95 %, The molar percentage content of glycolide is 5% -25%.
  • the toothed pipe suspension line of the present invention wherein the material of the toothed pipe is an L-lactide / DL-lactide-containing copolymer, and preferably, the molar percentage content of L-lactide is 60 % -95%, and the molar percentage of DL-lactide is 5% -40%.
  • toothed pipe suspension line of the present invention is further described below in combination with specific embodiments.
  • PCL Poly ⁇ -caprolactone
  • Poly-L-lactide (PLLA) was made into a multi-strand braided wire body by melt spinning with a diameter of 0.30 mm, a wire body length of 10 cm, and a wire breaking force of 38 N (N).
  • Poly-L-lactide / glycolide copolymer was used to make a toothed pipe by injection molding.
  • the outer diameter of the pipe body was 0.70 mm, the inner diameter was 0.30 mm, and the length was 3 mm.
  • the height is 0.5mm, the distance between the two tooth tips is 0.7mm, and each tooth forms an angle of 120 ° along the circumferential direction.
  • poly-L-lactide / glycolide copolymer can be synthesized by published conventional methods. The proportion is adjusted according to actual needs.
  • the molar percentage of L-lactide is 75% -95%, and the molar percentage of glycolide is 5% -25%.
  • a total of 5 toothed tubes in Example 3 were threaded on the thread body in Example 1, and the tooth directions on each toothed tube were the same, and then the toothed tubes were manually knotted to separate the toothed tubes.
  • One end of the suspension thread prepared in Example 4 is connected with a straight puncture needle, and the other end can be connected with a curved surgical suture needle.
  • Example 5 The suspension line of Example 5 was guided through the foam material of the simulated tissue through the puncture needle in accordance with the direction of the teeth. After all the toothed tubes entered the foam material, they were pulled outwards in the direction opposite to the teeth, using a mechanical testing machine The test pull strength was 21N.
  • a cone wire is prepared.
  • a hollow cone was made by injection molding, with a length of 3.0 mm, a large diameter of 1.42 mm, and a small diameter of 0.6 mm. Five of them were threaded on the thread body in Example 1, and the directions of the major and minor diameters of each cone were the same, and the hollow cones were separated by knotting manually.
  • the puncture needle was connected according to Example 5 and tested according to the method of Example 6. The pulling force was 11N.
  • Example 3 A total of eight toothed tubes in Example 3 were threaded on the thread body in Example 2. The teeth on each toothed tube were in the same direction, and the toothed tubes were manually knotted to separate the toothed tubes.
  • the puncture needle was connected according to Example 5 and tested according to the method of Example 6. The pulling force was 35N.
  • a cone wire is prepared.
  • a hollow cone was made by injection molding, with a length of 3.0 mm, a large diameter of 1.42 mm, and a small diameter of 0.6 mm. Eight of them were threaded on the thread body in Example 2. The directions of the major and minor diameters of each cone were the same, and the hollow cones were separated by knotting.
  • the puncture needle was connected according to Example 5 and tested according to the method of Example 6. The pulling force was 16N.

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Abstract

一种用于整形手术的带齿管悬提线,包括线体(1),线体(1)上分布多个线结(2),线体(1)上线结(2)间串有带齿管(3),带齿管(3)为中空管体(4),中空管体(4)外壁置有一个或一个以上、两个或两个以上、三个或三个以上径向突出于管体(4)外的齿(5);所述的线体(1)和带齿管(3)用可吸收材料制成。本发明的带齿管悬提线,它具有很好的线体强度,同时也具有很好的齿强度;通过带齿形的突出物,增加组织摩擦,使得提拉力大大提高。

Description

一种带齿管悬提线 技术领域
本发明涉及医疗器械,尤其涉及一种整形手术用的悬提线。
背景技术
用可吸收或不吸收线悬提皮肤组织达到面部年轻化已有多年的应用历史。其作用原理为,悬提线的线体上带有反向能产生阻力的结构件,经缝合针将其导入面部组织后,反向提拉,所产生的反向阻力会带动组织提升,以达到治疗面部轻度、中度衰老性损容病症的目的。
这类悬提线从其结构和方法特征来说主要分为三类,一类是反向能产生阻力的结构件为在线体上自身切割产生的齿所组成悬提线;第二类是整体热塑悬提线,包括全段线体和反向能产生阻力的结构件都是通过热压或注塑成型而形成的悬提线;第三类是反向能产生阻力的结构件为穿挂在线体上的空心锥体所组成的悬提线。
切割形成齿的这类悬提线,线体为经过拉伸取向而增强的单股纺丝线,其齿的产生是沿某个方向切割线体自身而形成许多倒齿,如CN101027168A 公开的有倒钩的缝合物。提拉原理是:当悬提线进入组织时,齿的方向顺应穿行方向,反向拽拉时齿尖插入组织并产生拽拉力可将组织提升。
整体热塑悬提线是通过热压或注塑方法在线体上形成许多倒齿,齿从线体上长出且和线体形成一体,没有切割,如强生公司的鱼骨线。提拉原理与切割形成齿的这类悬提线相同。
空心锥悬提线是将经注塑成型的空心锥体穿挂在线体上,线体可以是经过拉伸取向而增强的单股纺丝线,也可以是多股编织线,且沿这根线体均匀间隔打结,空心锥被固定在每两个线结之间,如US7582105B2和CN201404310Y公开的技术内容。提拉原理是,当悬提线进入组织时,锥体较小的尖部方向顺应穿行方向,反向拽拉时锥体较大的尾部产生反向阻力,带动组织提升。
不管是哪种结构的悬提线,对于提拉组织来说最重要的是提拉力的大小。
切割形成齿的悬提线,由于齿体不够坚硬,反向拽拉时容易变形、翻转或断裂,因此齿的提拉强度也最小;同时,线体由于被切割损伤,其张力强度也很小,容易被拉断,仅适用于拉力要求不大的细小部位提拉。
整体热塑悬提线,由于齿较厚实,提拉强度较大,但线体的张力强度与同直径的经过拉伸取向的单股纺丝线相比要小很多;同时,要想达到单股纺丝线同等强度以及可加工性,往往需要增大线体直径,这样可能会造 成植入物太多引起的炎性反应或患者的不舒适感。
空心锥悬提线,其线体也是为经过拉伸取向而增强的单股纺丝线或多股编织线,强度较大,但空心锥体没有齿的结构,只是靠锥体的反向阻力产生拽拉力,提拉力度过大时,有滑脱的可能。
发明内容
鉴于现有技术的以上不足,本发明的目的是提供一种带齿管悬提线,该带齿管悬提线具有更高的强度,在提拉时不会发生断裂或者滑脱。
一种带齿管悬提线,包括线体和串设在线体上的带齿管;
所述线体上设有用于限定带齿管位置的线结;
所述带齿管包括中空管体和设置在中空管体外壁并向外突出的齿。
该带齿管悬提线主要由线体和带齿管组成,其线体为经过拉伸取向而增强的单股纺丝线或多股编织线,具有很好的线体强度;其带齿管为热塑成型,通过管体上齿形的突出物,实现很好的齿强度,在提拉时不会发生断裂或者滑脱。
作为优选,所述的带齿管为两个或两个以上,所述的中空管体两端的管径相同或接近,所述的线结的尺寸大于中空管体的内径。
作为优选,所述的齿的齿根到齿尖的截面逐渐减小,所述的齿尖沿着所述中空管体的轴线向一方倾斜。
作为优选,每个带齿管上设有三个或三个以上的齿,所有的齿的齿尖 倾斜方向相同。
本发明中,所述的齿在中空管壁的任意位置,作为优选,任意两个齿不在中空管壁同一个圆周线上。
在所述的带齿管中,其两个齿之间沿着圆周方向成任意角度。作为优选,所述的中空管体外的齿有三个,其每个齿之间沿着圆周方向成120°角度。
作为优选,同一个中空管体上相邻两个齿(5)之间沿着所述中空管体轴向方向的距离为0-5mm。
作为优选,所述的齿的齿根到齿尖的长度为不超过5mm,所述的齿的齿根沿着所述中空管体轴向的宽度为0.1-4mm,所述的齿的齿根沿着所述中空管体周向的厚度为大于0.2mm。
作为优选,所述的齿的齿尖的倾斜度为10-80°该角度大致指的是齿体与中空管提轴向的夹角。
作为优选,线体上分布的线结可以是线体自身打的结,或是焊接上去的结,两结之间的距离可以任意调整。
本发明的带齿管悬提线,其中,所述的线体用可吸收材料经过拉伸取向或多股编织而成;带齿管用可吸收材料经过注塑成型制成。可吸收材料包括:L-丙交酯、DL-丙交酯、乙交酯、己内酯、三亚甲基碳酸酯、对二氧环己酮的均聚物或共聚物、均聚物或共聚物的共混物。
本发明的带齿管悬提线,其中,所述的带齿管的材料为L-丙交酯/乙交酯共聚物,优先地,L-丙交酯摩尔百分含量为75%-95%,乙交酯摩尔百分含量为5%-25%。
本发明的带齿管悬提线,其中,所述的带齿管的材料为含L-丙交酯/DL-丙交酯共聚物,优先地,L-丙交酯摩尔百分含量为60%-95%,DL-丙交酯摩尔百分含量为5%-40%。
同现有技术相比,本发明的带齿管悬提线具有下列优点:
(1)与整体热塑悬提线比较,两者齿的提拉强度相当,本发明的带齿管悬提线的线体为经过拉伸取向而增强的单股纺丝线或多股编织线,其线体张力强度更大。
(2)与切割形成齿的悬提线比较,本发明的带齿管悬提线,反向能产生阻力的结构件为注塑成型的带齿管,其齿的提拉强度和线体张力强度都更大,同时,也比同样是注塑成型的空心锥体对软组织的钩挂力量大。
(3)本发明综合了整体热塑悬提线其齿的提拉强度大和空心锥悬提线的线体强度大的优点,与空心锥悬提线比较,两者的线体张力强度相当,本发明的带齿管悬提线,其齿对组织的钩挂提拉力更大。
附图说明
图1为本发明的带齿管悬提线示意图。
图2为本发明的带齿管悬提线上带齿管示意图。
主要附图标记说明如下:
1为线体;2为线结;3为带齿管,4为中空管体;5为突出于管体外的齿。
具体实施方式
下面通过具体的实施方式,并结合附图对本发明做进一步详细的描述。
图1为本发明的带齿管悬提线,由图1可知,该带齿管悬提线,包括一根编织的或单股光滑的线体1,线体上分布有多个线结2,线体上线结间串有带齿管3,带齿管为中空管体4,中空管体外壁置有突出于管体外的齿5。
带齿管3的数目一般为三个或三个以上(图1中仅仅画出两个),中空管体两端的管径相同或接近。突出于管体外的齿5由齿尖朝一个方向倾斜的两个或两个以上组成,可以在管体上任意分布。
图2为带齿管3的结构示意图,由图2可知,在中空管体4的表面,其两个齿之间在管体上的相对位置不在同一个圆周线上;其两个齿之间沿着圆周方向成任意角度,优选地,其两个齿之间沿着圆周方向成120°角度。
作为一种常用的情况,所述的管体外的齿5有三个,其每个齿之间沿着圆周方向成120°角度。
本发明的带齿管悬提线,其中,所述的突出于管体外的齿5,其每个齿之间沿着管体纵向方向距离为0-5mm。
本发明的带齿管悬提线,其中,所述的突出于管体外的齿5,其齿尖的倾斜度为10-80°。
本发明的带齿管悬提线,其中,线体上分布的线结2可以是线体自身打的结,或是焊接上去的结,两结之间的距离可以任意调整;线结2的尺寸大于管体内径。
本发明的带齿管悬提线,其中,所述的线体和带齿管用可吸收材料制成,可吸收材料包括:L-丙交酯、DL-丙交酯、乙交酯、己内酯、三亚甲基碳酸酯、对二氧环己酮的均聚物或共聚物、均聚物或共聚物的共混物。
本发明的带齿管悬提线,其中,所述的带齿管的材料为L-丙交酯/乙交酯共聚物,优先地,L-丙交酯摩尔百分含量为75%-95%,乙交酯摩尔百分含量为5%-25%。
本发明的带齿管悬提线,其中,所述的带齿管的材料为含L-丙交酯/DL-丙交酯共聚物,优先地,L-丙交酯摩尔百分含量为60%-95%,DL-丙交酯摩尔百分含量为5%-40%。
下面结合具体实施例对本发明的带齿管悬提线做进一步的描述。
实施例1
用熔融纺丝法将聚ε-己内酯(PCL)制成单股线体,其直径为0.35mm之间,线体长度为10cm,线体的拉断力为26牛(N)。
实施例2
用熔融纺丝法将聚L-丙交酯(PLLA)制成多股编制线体,其直径为0.30mm之间,线体长度为10cm,线体的拉断力为38牛(N)。
实施例3
用聚L-丙交酯/乙交酯共聚物,注塑成型方法制成带齿管,管体的外径为0.70mm,内径为0.30mm,长度为3mm;管体上共有3齿,齿尖高度0.5mm,两个齿尖距离0.7mm,每个齿之间沿着圆周方向成120°角度。
聚L-丙交酯/乙交酯共聚物合成可以用公开常规方法合成,根据实际需要调整比例,L-丙交酯摩尔百分含量为75%-95%,乙交酯摩尔百分含量为5%-25%。
实施例4:
将实例3中的带齿管共5根,穿在实例1中的线体上,每根带齿管上齿的方向一致,再人工打结分隔带齿管。
实施例5
将实例4制得的悬提线一端连接直行的穿刺针,另一端可以连接弯型的手术缝合针。
实施例6
将实例5的悬提线,顺应齿的方向通过穿刺针引导穿过模拟组织的泡沫材料,当全部带齿管进入泡沫材料后,在反向逆着齿的方向往外拽拉,用力学测试机测试拽拉的力量为21N。
实施例7
按照US7582105B2的技术内容,制备锥体线。用注塑方法制得空心锥,其长度为3.0mm,大径为1.42mm,小径为0.6mm。将其5枚穿在实例1中的线体上,每个锥体大、小径方向都是一致,再人工打结分隔空心锥。再按照实例5连接上穿刺针,按照实例6方法进行测试,拽拉力为11N。
实施例6和7的结果表明,当采用的空心锥与带齿管尺寸大致相似时,数目相同时,本发明的带齿管悬提线可以明显提升拽拉力。
实施例8
将实例3中的带齿管共8根,穿在实例2中的线体上,每根带齿管上齿的方向一致,再人工打结分隔带齿管。再按照实例5连接上穿刺针,按照实例6方法进行测试,拽拉力为35N。
实施例9
按照US7582105B2的技术内容,制备锥体线。用注塑方法制得空心锥,其长度为3.0mm,大径为1.42mm,小径为0.6mm。将其8枚穿在实例2中的线体上,每个锥体大、小径方向都是一致,再人工打结分隔空心锥。再按照实例5连接上穿刺针,按照实例6方法进行测试,拽拉力为16N。
实施例8和9的结果表明,当采用的空心锥与带齿管尺寸大致相似时,数目相同时,本发明的带齿管悬提线可以明显提升拽拉力。

Claims (10)

  1. 一种带齿管悬提线,其特征在于,包括线体(1)和串设在线体(1)上的带齿管(3);
    所述线体(1)上设有用于限定带齿管(3)位置的线结(2);
    所述带齿管(3)包括中空管体(4)和设置在中空管体(4)外壁并向外突出的齿(5)。
  2. 根据权利要求1所述的带齿管悬提线,其特征在于,所述的带齿管(3)为两个或两个以上,所述的中空管体(4)两端的管径相同或接近,所述的线结(2)的尺寸大于中空管体(4)的内径。
  3. 根据权利要求1所述的带齿管悬提线,其特征在于,所述的齿(5)的齿根到齿尖的截面逐渐减小,所述的齿尖沿着所述中空管体(4)的轴线向一方倾斜。
  4. 根据权利要求3所述的带齿管悬提线,其特征在于,每个带齿管(3)上设有三个或三个以上的齿(5),所有的齿(5)的齿尖倾斜方向相同;
    任意两个齿(5)不在中空管壁同一个圆周线上。
  5. 根据权利要求4所述的带齿管悬提线,其特征在于,所述的中空管体外的齿(5)有三个,其每个齿之间沿着圆周方向成120°角度。
  6. 根据权利要求1~5任一项所述的带齿管悬提线,其特征在于,同一个中空管体(4)上相邻两个齿(5)之间沿着所述中空管体(4)轴向方向的距离为0-5mm。
  7. 根据权利要求1~5任一项所述的带齿管悬提线,其特征在于,所述的齿(5)的齿根到齿尖的长度为不超过5mm,所述的齿(5)的齿根 沿着所述中空管体(4)轴向的宽度为0.1-4mm,所述的齿(5)的齿根沿着所述中空管体(4)周向的厚度为大于0.2mm。
  8. 根据权利要求1~6任一项所述的带齿管悬提线,其特征在于,所述的齿(5)的齿尖的倾斜度为10-80°。
  9. 根据权利要求1所述的带齿管悬提线,其特征在于,所述的线体和带齿管用可吸收材料制成;
    所述的可吸收材料为L-丙交酯、DL-丙交酯、乙交酯、己内酯、三亚甲基碳酸酯、对二氧环己酮的均聚物或共聚物、均聚物或共聚物的共混物制成。
  10. 根据权利要求1或9所述的带齿管悬提线,其特征在于,所述的带齿管的材料为L-丙交酯/乙交酯共聚物或L-丙交酯/DL-丙交酯共聚物;
    作为优选,在所述的L-丙交酯/乙交酯共聚物中,L-丙交酯摩尔百分含量为75%-95%,乙交酯摩尔百分含量为5%-25%;
    所述的L-丙交酯/DL-丙交酯共聚物中,L-丙交酯摩尔百分含量为60%-95%,DL-丙交酯摩尔百分含量为5%-40%。
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Publication number Priority date Publication date Assignee Title
CN108784766A (zh) * 2018-07-05 2018-11-13 义乌美伦医疗科技有限公司 一种带齿管悬提线
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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101296661A (zh) * 2005-06-29 2008-10-29 伊西康公司 带倒刺的编织缝合线
CN201404310Y (zh) * 2009-05-22 2010-02-17 浙江普洛医药科技有限公司 整形手术用的空心锥悬提线
CN103083050A (zh) * 2008-04-15 2013-05-08 伊西康有限责任公司 具有双向保持器或单向保持器的自保持缝合线
KR20130069172A (ko) * 2011-12-16 2013-06-26 주식회사 삼양바이오팜 수술용 봉합사
CN104023651A (zh) * 2011-12-27 2014-09-03 约翰雅各医学股份有限公司 没有结的缝合线以及包含此缝合线的套组
CN206745401U (zh) * 2016-12-30 2017-12-15 广州迈普再生医学科技有限公司 一种手术缝合线
CN108784766A (zh) * 2018-07-05 2018-11-13 义乌美伦医疗科技有限公司 一种带齿管悬提线

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007303137B2 (en) * 2006-10-03 2014-04-10 Sinclair Pharmaceuticals Limited Minimally invasive tissue support
CN209004091U (zh) * 2018-07-05 2019-06-21 浙江中在医疗科技有限公司 一种带齿管悬提线

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101296661A (zh) * 2005-06-29 2008-10-29 伊西康公司 带倒刺的编织缝合线
US20130066369A1 (en) * 2005-06-29 2013-03-14 Ethicon, Inc. Braided barbed suture
CN103083050A (zh) * 2008-04-15 2013-05-08 伊西康有限责任公司 具有双向保持器或单向保持器的自保持缝合线
CN201404310Y (zh) * 2009-05-22 2010-02-17 浙江普洛医药科技有限公司 整形手术用的空心锥悬提线
KR20130069172A (ko) * 2011-12-16 2013-06-26 주식회사 삼양바이오팜 수술용 봉합사
CN104023651A (zh) * 2011-12-27 2014-09-03 约翰雅各医学股份有限公司 没有结的缝合线以及包含此缝合线的套组
CN206745401U (zh) * 2016-12-30 2017-12-15 广州迈普再生医学科技有限公司 一种手术缝合线
CN108784766A (zh) * 2018-07-05 2018-11-13 义乌美伦医疗科技有限公司 一种带齿管悬提线

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