WO2020007186A1 - 一种带齿管悬提线 - Google Patents
一种带齿管悬提线 Download PDFInfo
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- WO2020007186A1 WO2020007186A1 PCT/CN2019/091441 CN2019091441W WO2020007186A1 WO 2020007186 A1 WO2020007186 A1 WO 2020007186A1 CN 2019091441 W CN2019091441 W CN 2019091441W WO 2020007186 A1 WO2020007186 A1 WO 2020007186A1
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- WIPO (PCT)
- Prior art keywords
- toothed
- lactide
- tooth
- tube
- teeth
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06166—Sutures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
- A61B2017/0461—Means for attaching and blocking the suture in the suture anchor with features cooperating with special features on the suture, e.g. protrusions on the suture
- A61B2017/0462—One way system, i.e. also tensioning the suture
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0464—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors for soft tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B2017/06057—Double-armed sutures, i.e. sutures having a needle attached to each end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06166—Sutures
- A61B2017/06176—Sutures with protrusions, e.g. barbs
Definitions
- the invention relates to medical instruments, in particular to a suspension wire for plastic surgery.
- Suspension of skin tissue with absorbable or non-absorbable threads to achieve facial rejuvenation has been used for many years.
- the working principle is that the suspensory thread has a structural member that can generate resistance in the reverse direction. After it is introduced into the facial tissue by a suture needle, it is lifted in the opposite direction, and the generated reverse resistance will promote the tissue to improve. To achieve the goal of treating mild and moderate senile dysfunction.
- This type of suspension line is mainly divided into three types in terms of its structure and method characteristics.
- One type is a suspension line composed of teeth that can generate resistance in the reverse direction.
- the second type is the whole.
- Thermoplastic suspension lines, including the full length of the body and the structural components that can generate resistance in the reverse direction are all suspension lines formed by hot pressing or injection molding; the third type is the structural components that can generate resistance in the reverse direction.
- a suspension line consisting of a hollow cone on a wire.
- This type of suspension thread that is cut to form teeth is a single-stranded spinning thread that is strengthened by stretching and orientation.
- the teeth are generated by cutting the thread itself in a certain direction to form many inverted teeth.
- CN101027168A discloses Barbed suture. The lifting principle is: when the suspending line enters the tissue, the direction of the teeth conforms to the direction of travel. When the pulling direction is reversed, the tip of the teeth inserts into the tissue and generates a pulling force to lift the tissue.
- thermoplastic suspension line is formed with many inverted teeth on the wire body by hot pressing or injection molding.
- the teeth grow from the wire body and are integrated with the wire body without cutting, such as Johnson's fish bone line.
- the lifting principle is the same as this type of suspension line that is cut to form teeth.
- the hollow cone suspension thread is a hollow cone that is injection-molded and hung on a thread body.
- the thread body can be a single-stranded spinning thread reinforced by stretching and orientation, or a multi-strand braided thread, and along this line
- the body is knotted at regular intervals, and the hollow cone is fixed between every two knots, as disclosed in US7582105B2 and CN201404310Y.
- the principle of lifting is that when the suspending line enters the tissue, the direction of the smaller tip of the cone conforms to the direction of travel, and when pulling in the opposite direction, the tail of the larger cone generates reverse resistance, which drives the tissue to lift.
- Tooth suspension lines that are cut to form teeth Because the tooth body is not hard enough, it is easy to deform, flip or break when pulled in the opposite direction, so the pulling strength of the tooth is also the smallest. At the same time, because the wire body is damaged by cutting, its tensile strength is also small , Easy to be pulled off, only suitable for pulling small parts with small pull requirements.
- the overall thermoplastic suspension line has thicker teeth and higher pulling strength, but the tensile strength of the thread body is much smaller than that of a single-stranded spinning yarn of the same diameter.
- the same strength and processability of the strand spinning thread often requires increasing the diameter of the thread body, which may cause inflammatory reactions caused by too many implants or patient discomfort.
- Hollow cone suspension line its thread body is also a single-spun or multi-strand braided yarn reinforced by stretching orientation. The strength is greater, but the hollow cone has no tooth structure, but only depends on the reverse resistance of the cone. Pulling force is generated. If the pulling force is excessive, slipping may occur.
- an object of the present invention is to provide a toothed tube suspension line, which has a higher strength and does not break or slip off when pulled.
- a toothed pipe suspension line includes a wire body and a toothed pipe arranged in series on the wire body;
- a wire knot for limiting the position of the toothed pipe is provided on the wire body
- the toothed tube includes a hollow tube body and teeth provided on the outer wall of the hollow tube and protruding outward.
- the toothed tube suspension line is mainly composed of a thread body and a toothed tube.
- the thread body is a single-stranded spinning thread or a multi-strand braided wire reinforced by stretching and orientation, and has good thread body strength.
- the pipe is made of thermoplastic. Through the tooth-shaped protrusions on the pipe body, good tooth strength is achieved, and no breakage or slippage occurs during pulling.
- the diameters of the two ends of the hollow tube body are the same or close to each other, and the size of the knot is larger than the inner diameter of the hollow tube body.
- a cross section of a tooth root to a tooth tip of the tooth gradually decreases, and the tooth tip is inclined to one side along an axis of the hollow pipe body.
- each toothed tube is provided with three or more teeth, and the tip angles of all the teeth are the same.
- the teeth are at any position on the hollow tube wall.
- any two teeth are not on the same circumferential line of the hollow tube wall.
- the two teeth of the toothed tube make an arbitrary angle along the circumferential direction.
- the distance between two adjacent teeth (5) on the same hollow pipe body along the axial direction of the hollow pipe body is 0-5 mm.
- the length from the root of the tooth to the tip of the tooth is not more than 5 mm, and the width of the root of the tooth along the axial direction of the hollow pipe body is 0.1-4 mm, and the tooth of the tooth The thickness of the root along the circumferential direction of the hollow pipe body is greater than 0.2 mm.
- the inclination of the tooth tips of the teeth is 10-80 °, and the angle generally refers to an included angle between the tooth body and the axial direction of the hollow pipe.
- the knots distributed on the wire body may be knots knotted by the wire body itself or welded knots, and the distance between the two knots may be arbitrarily adjusted.
- the thread body is made of an absorbent material through stretch orientation or multi-strand braiding; the toothed pipe is made of an absorbable material by injection molding.
- Absorbable materials include: L-lactide, DL-lactide, glycolide, caprolactone, trimethylene carbonate, homopolymers or copolymers, homopolymers or copolymers of dioxocyclohexanone Of blends.
- the toothed pipe suspension line of the present invention wherein the material of the toothed pipe is an L-lactide / glycolide copolymer, and preferably, the molar percentage content of the L-lactide is 75% -95 %, The molar percentage content of glycolide is 5% -25%.
- the toothed pipe suspension line of the present invention wherein the material of the toothed pipe is an L-lactide / DL-lactide-containing copolymer, and preferably, the molar percentage content of L-lactide is 60 % -95%, and the molar percentage of DL-lactide is 5% -40%.
- the toothed pipe suspension line of the present invention has the following advantages:
- the thread body of the suspension line with a toothed tube of the present invention is a single-stranded spinning line or a multi-strand braid reinforced by stretching orientation. Thread, its thread body has greater tensile strength.
- the structure of the suspension pipe with toothed tube of the present invention can generate resistance in the reverse direction is an injection-molded toothed tube.
- the tooth pull strength and the wire body tensile strength Both are larger, and at the same time, they have a stronger hooking force on soft tissues than the injection-molded hollow cone.
- the present invention combines the advantages of the overall thermoplastic suspension line with its strong pulling strength of the teeth and the strength of the hollow body of the hollow cone suspension line. Compared with the hollow cone suspension line, the tension strength of the two bodies is equivalent.
- the toothed tube suspension line of the present invention has a greater hooking and pulling force of the teeth on the tissue.
- FIG. 1 is a schematic diagram of a toothed pipe suspension line according to the present invention.
- FIG. 2 is a schematic view of a toothed tube on a toothed tube suspension line of the present invention.
- FIG. 1 is a toothed pipe suspension line of the present invention.
- the toothed pipe suspension line includes a woven or single-smooth smooth thread body 1, and a plurality of knots 2 are distributed on the thread body.
- a toothed tube 3 is connected in series between the wire knots on the thread body, the toothed tube is a hollow tube body 4, and the outer wall of the hollow tube is provided with teeth 5 protruding outside the tube body.
- the number of toothed pipes 3 is generally three or more (only two are shown in FIG. 1), and the diameters of the two ends of the hollow pipe body are the same or close to each other.
- the teeth 5 protruding from the outside of the tube are composed of two or more teeth whose tooth tips are inclined in one direction, and can be randomly distributed on the tube.
- FIG. 2 is a schematic structural diagram of a toothed pipe 3.
- the relative positions of the two teeth on the pipe body are not on the same circumferential line;
- the teeth are arranged at any angle along the circumferential direction.
- the two teeth are arranged at an angle of 120 ° along the circumferential direction.
- each of the teeth has an angle of 120 ° along the circumferential direction.
- the toothed pipe suspension line of the present invention wherein the distance between each tooth of the teeth 5 protruding outside the pipe body along the longitudinal direction of the pipe body is 0-5 mm.
- the inclination of the tooth tips of the teeth 5 protruding outside the pipe is 10-80 °.
- the knots 2 distributed on the wire body can be knots welded by the wire body or welded knots, and the distance between the two knots can be arbitrarily adjusted;
- the size is larger than the inner diameter of the tube.
- the toothed pipe suspension line of the present invention wherein the thread body and the toothed pipe are made of an absorbable material, and the absorbable material includes: L-lactide, DL-lactide, glycolide, caprolactone Homopolymers or copolymers of esters, trimethylene carbonate, p-dioxane, blends of homopolymers or copolymers.
- the toothed pipe suspension line of the present invention wherein the material of the toothed pipe is an L-lactide / glycolide copolymer, and preferably, the molar percentage content of the L-lactide is 75% -95 %, The molar percentage content of glycolide is 5% -25%.
- the toothed pipe suspension line of the present invention wherein the material of the toothed pipe is an L-lactide / DL-lactide-containing copolymer, and preferably, the molar percentage content of L-lactide is 60 % -95%, and the molar percentage of DL-lactide is 5% -40%.
- toothed pipe suspension line of the present invention is further described below in combination with specific embodiments.
- PCL Poly ⁇ -caprolactone
- Poly-L-lactide (PLLA) was made into a multi-strand braided wire body by melt spinning with a diameter of 0.30 mm, a wire body length of 10 cm, and a wire breaking force of 38 N (N).
- Poly-L-lactide / glycolide copolymer was used to make a toothed pipe by injection molding.
- the outer diameter of the pipe body was 0.70 mm, the inner diameter was 0.30 mm, and the length was 3 mm.
- the height is 0.5mm, the distance between the two tooth tips is 0.7mm, and each tooth forms an angle of 120 ° along the circumferential direction.
- poly-L-lactide / glycolide copolymer can be synthesized by published conventional methods. The proportion is adjusted according to actual needs.
- the molar percentage of L-lactide is 75% -95%, and the molar percentage of glycolide is 5% -25%.
- a total of 5 toothed tubes in Example 3 were threaded on the thread body in Example 1, and the tooth directions on each toothed tube were the same, and then the toothed tubes were manually knotted to separate the toothed tubes.
- One end of the suspension thread prepared in Example 4 is connected with a straight puncture needle, and the other end can be connected with a curved surgical suture needle.
- Example 5 The suspension line of Example 5 was guided through the foam material of the simulated tissue through the puncture needle in accordance with the direction of the teeth. After all the toothed tubes entered the foam material, they were pulled outwards in the direction opposite to the teeth, using a mechanical testing machine The test pull strength was 21N.
- a cone wire is prepared.
- a hollow cone was made by injection molding, with a length of 3.0 mm, a large diameter of 1.42 mm, and a small diameter of 0.6 mm. Five of them were threaded on the thread body in Example 1, and the directions of the major and minor diameters of each cone were the same, and the hollow cones were separated by knotting manually.
- the puncture needle was connected according to Example 5 and tested according to the method of Example 6. The pulling force was 11N.
- Example 3 A total of eight toothed tubes in Example 3 were threaded on the thread body in Example 2. The teeth on each toothed tube were in the same direction, and the toothed tubes were manually knotted to separate the toothed tubes.
- the puncture needle was connected according to Example 5 and tested according to the method of Example 6. The pulling force was 35N.
- a cone wire is prepared.
- a hollow cone was made by injection molding, with a length of 3.0 mm, a large diameter of 1.42 mm, and a small diameter of 0.6 mm. Eight of them were threaded on the thread body in Example 2. The directions of the major and minor diameters of each cone were the same, and the hollow cones were separated by knotting.
- the puncture needle was connected according to Example 5 and tested according to the method of Example 6. The pulling force was 16N.
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Abstract
Description
Claims (10)
- 一种带齿管悬提线,其特征在于,包括线体(1)和串设在线体(1)上的带齿管(3);所述线体(1)上设有用于限定带齿管(3)位置的线结(2);所述带齿管(3)包括中空管体(4)和设置在中空管体(4)外壁并向外突出的齿(5)。
- 根据权利要求1所述的带齿管悬提线,其特征在于,所述的带齿管(3)为两个或两个以上,所述的中空管体(4)两端的管径相同或接近,所述的线结(2)的尺寸大于中空管体(4)的内径。
- 根据权利要求1所述的带齿管悬提线,其特征在于,所述的齿(5)的齿根到齿尖的截面逐渐减小,所述的齿尖沿着所述中空管体(4)的轴线向一方倾斜。
- 根据权利要求3所述的带齿管悬提线,其特征在于,每个带齿管(3)上设有三个或三个以上的齿(5),所有的齿(5)的齿尖倾斜方向相同;任意两个齿(5)不在中空管壁同一个圆周线上。
- 根据权利要求4所述的带齿管悬提线,其特征在于,所述的中空管体外的齿(5)有三个,其每个齿之间沿着圆周方向成120°角度。
- 根据权利要求1~5任一项所述的带齿管悬提线,其特征在于,同一个中空管体(4)上相邻两个齿(5)之间沿着所述中空管体(4)轴向方向的距离为0-5mm。
- 根据权利要求1~5任一项所述的带齿管悬提线,其特征在于,所述的齿(5)的齿根到齿尖的长度为不超过5mm,所述的齿(5)的齿根 沿着所述中空管体(4)轴向的宽度为0.1-4mm,所述的齿(5)的齿根沿着所述中空管体(4)周向的厚度为大于0.2mm。
- 根据权利要求1~6任一项所述的带齿管悬提线,其特征在于,所述的齿(5)的齿尖的倾斜度为10-80°。
- 根据权利要求1所述的带齿管悬提线,其特征在于,所述的线体和带齿管用可吸收材料制成;所述的可吸收材料为L-丙交酯、DL-丙交酯、乙交酯、己内酯、三亚甲基碳酸酯、对二氧环己酮的均聚物或共聚物、均聚物或共聚物的共混物制成。
- 根据权利要求1或9所述的带齿管悬提线,其特征在于,所述的带齿管的材料为L-丙交酯/乙交酯共聚物或L-丙交酯/DL-丙交酯共聚物;作为优选,在所述的L-丙交酯/乙交酯共聚物中,L-丙交酯摩尔百分含量为75%-95%,乙交酯摩尔百分含量为5%-25%;所述的L-丙交酯/DL-丙交酯共聚物中,L-丙交酯摩尔百分含量为60%-95%,DL-丙交酯摩尔百分含量为5%-40%。
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CN201810729346.3 | 2018-07-05 | ||
CN201810729346.3A CN108784766A (zh) | 2018-07-05 | 2018-07-05 | 一种带齿管悬提线 |
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CN (1) | CN108784766A (zh) |
TW (1) | TW202014152A (zh) |
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CN108784766A (zh) * | 2018-07-05 | 2018-11-13 | 义乌美伦医疗科技有限公司 | 一种带齿管悬提线 |
CN113274078A (zh) * | 2021-04-07 | 2021-08-20 | 长春圣博玛生物材料有限公司 | 一种医用缝合线及其制备方法 |
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2018
- 2018-07-05 CN CN201810729346.3A patent/CN108784766A/zh active Pending
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2019
- 2019-06-05 TW TW108119511A patent/TW202014152A/zh unknown
- 2019-06-15 WO PCT/CN2019/091441 patent/WO2020007186A1/zh active Application Filing
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CN103083050A (zh) * | 2008-04-15 | 2013-05-08 | 伊西康有限责任公司 | 具有双向保持器或单向保持器的自保持缝合线 |
CN201404310Y (zh) * | 2009-05-22 | 2010-02-17 | 浙江普洛医药科技有限公司 | 整形手术用的空心锥悬提线 |
KR20130069172A (ko) * | 2011-12-16 | 2013-06-26 | 주식회사 삼양바이오팜 | 수술용 봉합사 |
CN104023651A (zh) * | 2011-12-27 | 2014-09-03 | 约翰雅各医学股份有限公司 | 没有结的缝合线以及包含此缝合线的套组 |
CN206745401U (zh) * | 2016-12-30 | 2017-12-15 | 广州迈普再生医学科技有限公司 | 一种手术缝合线 |
CN108784766A (zh) * | 2018-07-05 | 2018-11-13 | 义乌美伦医疗科技有限公司 | 一种带齿管悬提线 |
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